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Targeting polyamines of parasitic protozoa in chemotherapy
TRENDS IN PARASITOLOGY
New drugs for the treatment of human African trypanosomiasis: research anddevelopment
TRENDS IN PARASITOLOGY
A mammalian sequence-dependent upstream open reading frame mediates polyamine-regulated translation in yeast
RNA-A PUBLICATION OF THE RNA SOCIETY
Biochemical and ultrastructural features related to male sterility in the dioecious species Actinidia deliciosa
PLANT PHYSIOLOGY AND BIOCHEMISTRY
Expression of host S-adenosylmethionine decarboxylase gene and polyamine composition in aphid bacteriocytes
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
Novel alkylpolyamine analogues that possess both antitrypanosomal and antimicrosporidial activity
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Arabidopsis polyamine biosynthesis: absence of ornithine decarboxylase andthe mechanism of arginine decarboxylase activity
PLANT JOURNAL
Polyamine metabolism revisited
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Biosynthesis, oxidation and conjugation of aliphatic polyamines in higher plants
AMINO ACIDS
Effect of drugs inhibiting spermidine biosynthesis and metabolism on the in vitro development of Plasmodium falciparum
PARASITOLOGY RESEARCH
Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
Tumour promoter mediated altered expression and regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in H-ras-transformed fibrosarcoma cell lines
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
S-adenosytmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progression
JOURNAL OF CELLULAR BIOCHEMISTRY
Inhibition of CHOP translation by a peptide encoded by an open reading frame localized in the chop 5 ' UTR
NUCLEIC ACIDS RESEARCH
Importance of the 3 ' untranslated region of ornithine decarboxylase mRNA in the translational regulation of the enzyme
BIOCHEMICAL JOURNAL
Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
The early increase of S-adenosylmethionine decarboxylase activity is essential for the normal germination and tube growth in tomato (Lycopersicon esculentum Mill.) pollen
PLANT SCIENCE
Genetic analysis of spermidine synthase from Leishmania donovani
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Translational control in vertebrate development
INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 203
The regulation of ornithine decarboxylase gene expression by sucrose and small upstream open reading frame in tomato (Lycopersicon esculentum Mill)
PLANT AND CELL PHYSIOLOGY
Polyamine metabolism is upregulated in response to tobacco mosaic virus inhypersensitive, but not in susceptible, tobacco
NEW PHYTOLOGIST
Effect of spermidine on the in vivo degradation of ornithine decarboxylasein Saccharomyces cerevisiae
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Terminally alkylated polyamine analogues as chemotherapeutic agents
JOURNAL OF MEDICINAL CHEMISTRY
Antizyme regulates the degradation of ornithine decarboxylase in fission yeast Schizosaccharomyces pombe - Study in the spe2 knockout strains
JOURNAL OF BIOLOGICAL CHEMISTRY
Polyamine depletion in human melanoma cells leads to G(1) arrest associated with induction of p21(,)(WAF1/CIP1/SDI1) changes in the expression of p21-regulated genes, and a senescence-like phenotype
CANCER RESEARCH
Glutamate 47 in 1-aminocyclopropane-1-carboxylate synthase is a major specificity determinant
BIOCHEMISTRY
Hydroxylamine-containing inhibitors of polyamine biosynthesis and impairment of colon cancer cell growth
BIOCHEMICAL PHARMACOLOGY
Guanidino-containing drugs in cancer chemotherapy: biochemical and clinical pharmacology
BIOCHEMICAL PHARMACOLOGY
Polyamines: Biosynthesis, metabolism, and their role in ripening and postharvest handling of fruits
FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL
Phase I and pharmacological study of weekly administration of the polyamine synthesis inhibitor SAM 486A (CGP 48 664) in patients with solid tumors
CLINICAL CANCER RESEARCH
Characterization and translational regulation of the arginine decarboxylase gene in carnation (Dianthus caryophyllus L.)
PLANT JOURNAL
Acute glomerular upregulation of ornithine decarboxylase is not essential for mesangial cell proliferation and matrix expansion in anti-Thy-1-nephritis
NEPHROLOGY DIALYSIS TRANSPLANTATION
Insulin-mediated alterations in S-adenosylmethionine decarboxylase expression in H-ras transformed cells of varying degrees of malignancy
CELLULAR SIGNALLING
Isolation and characterization of human breast adenocarcinoma cells made resistant to alpha-difluoromethylornithine
CANCER INVESTIGATION
Oxidation of polyamines and brain injury
NEUROCHEMICAL RESEARCH
Maternal program of apoptosis activated shortly after midblastula transition by overexpression of S-adenosylmethionine decarboxylase in Xenopus earlyembryos
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Polyamine synthesis in plants: isolation and characterization of spermidine synthase from soybean (Glycine max) axes
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Altered ornithine decarboxylase and S-adenosylmethionine decarboxylase expression and regulation in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein (MAP) kinase kinase
MOLECULAR AND CELLULAR BIOCHEMISTRY
Upstream open reading frames as regulators of mRNA translation
MOLECULAR AND CELLULAR BIOLOGY
Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to1,3-bis-(2-chloroethyl)-N-nitrosourea
BIOCHEMICAL JOURNAL
Changes in gene expression in response to polyamine depletion indicates selective stabilization of mRNAs
BIOCHEMICAL JOURNAL
Putrescine does not support the migration and growth of IEC-6 cells
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Isolation and characterization of a salt- and drought-inducible gene for S-adenosylmethionine decarboxylase from wheat (Triticum aestivum L.)
JOURNAL OF PLANT PHYSIOLOGY
Growth inhibition in suspension-cultured soybean cells in the presence of ferulic acid is mediated through spermine accumulation
JOURNAL OF PLANT PHYSIOLOGY
Population pharmacokinetics/toxicodynamics (PK/TD) relationship of SAM486Ain phase I studies in patients with advanced cancers
JOURNAL OF CLINICAL PHARMACOLOGY
Differential accumulation of the S-adenosylmethionine decarboxylase transcript in rice seedlings in response to salt and drought stresses
THEORETICAL AND APPLIED GENETICS
Biosynthesis of spermidine, a direct precursor of pyrrolizidine alkaloids in root cultures of Senecio vulgaris L.
PLANTA
Cloning and expression of the S-adenosylmethionine decarboxylase gene of Neurospora crassa and processing of its product
MOLECULAR AND GENERAL GENETICS
Dietary soy protein is associated with reduced intestinal mucosal polyamine concentration in male Wistar rats
JOURNAL OF NUTRITION
c-Jun activation-dependent tumorigenic transformation induced paradoxically by overexpression or block of S-adenosylmethionine decarboxylase
JOURNAL OF CELL BIOLOGY
Effects of conditional overexpression of spermidine/spermine N-1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of an alternatively spliced seprase mRNA that encodes a novel intracellular isoform
JOURNAL OF BIOLOGICAL CHEMISTRY
Evolutionarily conserved features of the arginine attenuator peptide provide the necessary requirements for its function in translational regulation
JOURNAL OF BIOLOGICAL CHEMISTRY
Influence of physical exercise on polyamine synthesis in the rat skeletal muscle
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
A phase I study of a new polyamine biosynthesis inhibitor, SAM486A, in cancer patients with solid tumours
BRITISH JOURNAL OF CANCER
Translational pathophysiology: a novel molecular mechanism of human disease
BLOOD
Translational control: the cancer connection
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Biological effects of aminoguanidine: An update
INFLAMMATION RESEARCH
The crystal structure of human S-adenosylmethionine decarboxylase at 2.25 angstrom resolution reveals a novel fold
STRUCTURE WITH FOLDING & DESIGN
Mammalian Cu-containing amine oxidases (CAOs): New methods of analysis, structural relationships, and possible functions
APMIS
Topoisomerase II is nonfunctional in polyamine-depleted cells
JOURNAL OF CELLULAR BIOCHEMISTRY
Gene structure and chromosomal localization of mouse S-adenosylmethionine decarboxylase
GENE
The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems
PROGRESS IN NEUROBIOLOGY
Molecular cloning and characterization of coffee cDNA encoding spermidine synthase
PLANT SCIENCE
Differential expression of two spermidine synthase genes during early fruit development and in vegetative tissues of pea
PLANT MOLECULAR BIOLOGY
Cloning and kinetic characterization of the Trypanosoma cruzi S-adenosylmethionine decarboxylase
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
It all started on a streetcar in Boston
ANNUAL REVIEW OF BIOCHEMISTRY
On the possibility of carbamate-directed hydroboration. An approach to theasymmetric synthesis of 1-aminocyclopentane-1,3-dicarboxylic acid
TETRAHEDRON
Polyamine conjugate levels and ethylene biosynthesis: inverse relationshipwith vegetative bud formation in tobacco thin layers
PHYSIOLOGIA PLANTARUM
Effect of retinoic acid on proliferation and polyamine metabolism in cultured bovine retinal pigment epithelial cells
OPHTHALMIC RESEARCH
Blue- and red-light regulation and circadian control of gene expression ofS-adenosylmethionine decarboxylase in Pharbitis nil
JOURNAL OF EXPERIMENTAL BOTANY
Identification of functionally important residues of Arabidopsis thaliana S-adenosylmethionine decarboxylase
JOURNAL OF BIOCHEMISTRY
Coordinate changes of polyamine metabolism regulatory proteins during the cell cycle of normal human dermal fibroblasts
FEBS LETTERS
Metabolic effects of a methylthioadenosine phosphorylase substrate analog on African trypanosomes
BIOCHEMICAL PHARMACOLOGY
Half-lives of ornithine decarboxylase and S-adenosylmethionine decarboxylase activities during the cell cycle of Chinese hamster ovary cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Polyamines: agents with macrofilaricidal activity
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY
INTERACTION OF CATIONIC DIAMIDINES WITH LEISHMANIA-INFANTUM DNA
Biological chemistry
Control of translation initiation in animals
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
POLYAMINE POOLS IN HIV-INFECTED CELLS
Journal of acquired immune deficiency syndromes and human retrovirology
Retarded growth of an Escherichia coli mutant deficient in spermidine synthase can be unspecifically repaired by addition of various polyamines
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
EFFECTS OF POLYAMINE SYNTHESIS INHIBITION ON POLYAMINES, GROWTH AND MECHANICAL-PROPERTIES IN HYPERTROPHIC RAT URINARY-BLADDER
Pharmacology & toxicology
DEVELOPMENTAL REGULATION OF THE BRAIN POLYAMINE-STRESS-RESPONSE
International journal of developmental neuroscience
MOLECULAR-GENETIC ANALYSES OF PLANT POLYAMINES
Critical reviews in plant sciences
SPERMINE IS NOT ESSENTIAL FOR GROWTH OF SACCHAROMYCES-CEREVISIAE - IDENTIFICATION OF THE SPE4 GENE (SPERMINE SYNTHASE) AND CHARACTERIZATIONOF A SPE4 DELETION MUTANT
Gene
DIFFERENTIAL EFFECT ON POLYAMINE METABOLISM IN MITOGEN-ACTIVATED AND SUPERANTIGEN-ACTIVATED HUMAN T-CELLS
Biochimica et biophysica acta (G). General subjects
IN-VIVO MANIPULATION OF L1210 CELL-CYCLE PHASE DISTRIBUTION WITH ALPHA-DIFLUOROMETHYLORNITHINE, 4-AMIDINOINDAN-1-ONE 2'-AMIDINOHYDRAZONE AND N-1-ACETYLSPERMINE
Biochimica et biophysica acta (G). General subjects
IN-VITRO MANIPULATION OF L1210 CELL-CYCLE KINETICS WITH 4-AMIDINOINDAN-1-ONE 2'-AMIDINOHYDRAZONE, ALPHA-DIFLUOROMETHYLORNITHINE AND N-1-ACETYLSPERMINE
Biochimica et biophysica acta (G). General subjects
HUMAN PROSTATIC-CARCINOMA CELL-LINES DISPLAY ALTERED REGULATION OF POLYAMINE TRANSPORT IN RESPONSE TO POLYAMINE ANALOGS AND INHIBITORS
The Prostate
MGBG analogues as potent inhibitors of S-adenosylmethionine decarboxylase of Onchocerca volvulus
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
MOLECULAR-CLONING OF PLANT SPERMIDINE SYNTHASES
Plant and Cell Physiology
Photoinduction of arginine decarboxylase activity in leaves of Pharbitis nil
PHYTOCHEMISTRY
ORNITHINE DECARBOXYLASE IN HUMAN BRAIN - INFLUENCE OF AGING, REGIONALDISTRIBUTION, AND ALZHEIMERS-DISEASE
Journal of neurochemistry
LIGHT-REGULATED GENE-EXPRESSION OF S-ADENOSYLMETHIONINE DECARBOXYLASEIN PHARBITIS-NIL
Journal of Experimental Botany
The identification of a cis-element and a trans-acting factor involved in the response to polyamines and polyamine analogues in the regulation of thehuman spermidine/spermine N-1-acetyltransferase gene transcription
JOURNAL OF BIOLOGICAL CHEMISTRY
CONCOMITANT CHANGES IN POLYAMINE POOLS AND DNA METHYLATION DURING GROWTH-INHIBITION OF HUMAN COLONIC-CANCER CELLS
Experimental cell research
MOLECULAR ANALYSIS OF POLYAMINE BIOSYNTHESIS IN HIGHER-PLANTS
Current Science
SIGNIFICANT INCREASES IN THE STEADY-STATES OF PUTRESCINE AND SPERMIDINE SPERMINE N-1-ACETYLTRANSFERASE MESSENGER-RNA IN HELA-CELLS ACCOMPANIED BY GROWTH ARREST/
Biochemical and biophysical research communications
RECENT ADVANCES IN POLYAMINE RESEARCH
Trends in plant science
EFFECTS OF CARBOXYLMETHYLATION AND POLYAMINE SYNTHESIS INHIBITORS ON METHYLATION OF TRYPANOSOMA-BRUCEI CELLULAR PROTEINS AND LIPIDS
The Journal of eukaryotic microbiology