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Transforming growth factor: signal transduction pathways, cell cycle mediation, and effects on hematopoiesis
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
The INK4a/ARF network in tumour suppression
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Crosstalk between cell cycle regulators and the myogenic factor MyoD in skeletal myoblasts
CELLULAR AND MOLECULAR LIFE SCIENCES
Alteration of pRb expression in the development of rat tongue carcinoma induced by 4-nitroquinoline 1-oxide
ORAL ONCOLOGY
A high degree of chromosomal instability at 13q14 in cutaneous squamous cell carcinomas: indication for a role of a tumour suppressor gene other thanRb
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
Interplay between the antimetastatic nm23 and the Retinoblastoma-related Rb2/p130 genes in promoting neuronal differentiation of PC12 cells
CELL DEATH AND DIFFERENTIATION
Retinoids: New insight into smooth muscle cell growth inhibition
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Synchronous oral leiomyosarcoma and squamous cell carcinoma
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS
Sarcomatoid renal cell carcinoma: basic biology, clinical behavior and response to therapy
UROLOGIC ONCOLOGY
UCN-01 suppresses E2F-1 mediated by ubiquitin-proteasome-dependent degradation
CLINICAL CANCER RESEARCH
Differential control of transcription by DNA-bound cyclins
MOLECULAR BIOLOGY OF THE CELL
Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
MOLECULAR BIOLOGY OF THE CELL
NUP98 gene rearrangements and the clonal evolution of chronic myelogenous leukemia
GENES CHROMOSOMES & CANCER
Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres
CELL GROWTH & DIFFERENTIATION
Cellular transformation by SV40 large T antigen: interaction with host proteins
SEMINARS IN CANCER BIOLOGY
SV40 and cell cycle perturbations in malignant mesothelioma
SEMINARS IN CANCER BIOLOGY
Hepatitis B viral X protein overcomes inhibition of E2F1 activity by pRb on the human Rb gene promoter
DNA AND CELL BIOLOGY
Retinoblastoma gene product and p21 (WAF1, CIP1) protein expression in nonHodgkin's lymphomas: A multivariate survival analysis
LEUKEMIA & LYMPHOMA
Estrogenic effects on prostatic differentiation and carcinogenesis
REPRODUCTION FERTILITY AND DEVELOPMENT
Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU
INTERNATIONAL JOURNAL OF ONCOLOGY
Tumor suppressor loss in pituitary tumors
BRAIN PATHOLOGY
Transgenic and knockout mouse models clarify pituitary development, function and disease
BRAIN PATHOLOGY
Transcriptional control at regulatory checkpoints by histone deacetylases:molecular connections between cancer and chromatin
HUMAN MOLECULAR GENETICS
The Rb/E2F pathway and cancer
HUMAN MOLECULAR GENETICS
Hormonal regulation of tumor suppressor proteins in breast cancer cells
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
Biology of human papillomaviruses
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
pRb-expressing adenovirus Ad5-Rb attenuates the p53-induced apoptosis in cervical cancer cell lines
EUROPEAN JOURNAL OF CANCER
The Rb pathway in neurogenesis
NEUROREPORT
Thymic hyperplasia and lung carcinomas in a line of mice transgenic for keratin 5-driven HPV16 E6/E7 oncogenes
ONCOGENE
Adenovirus E1A: remodelling the host cell, a life or death experience
ONCOGENE
Oncogenic transformation by the human polyomaviruses
ONCOGENE
The HPV-16 E7 oncoprotein binds Skip and suppresses its transcriptional activity
ONCOGENE
The proliferative and apoptotic activities of E2F1 in the mouse retina
ONCOGENE
p202, an interferon-inducible negative regulator of cell growth, is a target of the adenovirus E1A protein
ONCOGENE
Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130
ONCOGENE
Ras adenoviruses modulate cyclin E protein expression and DNA synthesis after partial hepatectomy
ONCOGENE
Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression
ONCOGENE
Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells
ONCOGENE
Differential post-translational modification of the tumour suppressor proteins Rb and p53 modulate the rates of radiation-induced apoptosis in vivo
ONCOGENE
The p107 tumor suppressor induces stable E2F DNA binding to repress targetpromoters
ONCOGENE
lin-35 Rb and cki-1 Cip/Kip cooperate in developmental regulation of G1 progression in C-elegans
DEVELOPMENT
Replicating adenoviral vector-mediated transfer of a heat-inducible doublesuicide gene for gene therapy
CANCER GENE THERAPY
Aberrant expression of pRb, p16, p14ARF, MDM2, p21 and p53 in squamous cell carcinomas of lung
JAPANESE JOURNAL OF CANCER RESEARCH
An 800-kb region of deletion at 13q14 in human prostate and other carcinomas
GENOMICS
Cell cycle regulatory protein expression in fresh acute myeloid leukemia cells and after drug exposure
LEUKEMIA
Deletion of chromosomal region 13q14.3 in childhood acute lymphoblastic leukemia
LEUKEMIA
Mutation of the p51/p63 gene is associated with blastic crisis in chronic myelogenous leukemia
LEUKEMIA
Biological methods for cell-cycle synchronization of mammalian cells
BIOTECHNIQUES
Alterations in the regulatory pathway involving p16, pRb and cdk4 in humanchondrosarcoma
JOURNAL OF ORTHOPAEDIC RESEARCH
Simian virus 40 large tumor antigen forms specific complexes with p53 and pRb in human brain tumors
CHINESE MEDICAL JOURNAL
Targets for molecular intervention in multistep pulmonary carcinogenesis
WORLD JOURNAL OF SURGERY
Centrosome abnormalities, genomic instability and carcinogenic progression
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Alteration of cyclin D1 and CDK4 gene in carcinoma of uterine cervix
CANCER LETTERS
Neuronal apoptosis at the G1/S cell cycle checkpoint
CELL AND TISSUE RESEARCH
Distinct clonal composition of primary and metastatic adrencorticotrophic hormone-producing pituitary carcinoma
CLINICAL ENDOCRINOLOGY
Loss of heterozygosity at the RB-1 locus and pRB immunostaining in epithelial ovarian tumors: A molecular, immunohistochemical, and clinicopathologicstudy
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
Mpe1, a zinc knuckle protein, is an essential component of yeast cleavage and polyadenylation factor required for the cleavage and polyadenylation ofmRNA
MOLECULAR AND CELLULAR BIOLOGY
Molecular basis for impaired muscle differentiation in myotonic dystrophy
MOLECULAR AND CELLULAR BIOLOGY
MAT1-modulated CAK activity regulates cell cycle G(1) exit
MOLECULAR AND CELLULAR BIOLOGY
Loss of heterozygosity at 13q14 and 13q21 in high grade, high stage prostate cancer
PROSTATE
TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1
EMBO JOURNAL
LOH analyses in the region of the putative tumour suppressor gene C13 on chromosome 13q13
ANTICANCER RESEARCH
Immunohistochemical expression of the p53, mdm2, p21/Waf-1, Rb, p16, Ki67,cyclin D1, cyclin A and cyclin B1 proteins and apoptotic index in T-cell lymphomas
HISTOLOGY AND HISTOPATHOLOGY
Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II
LUNG CANCER
Oral gossypol in the treatment of patients with refractory metastatic breast cancer: A phase I/II clinical trial
BREAST CANCER RESEARCH AND TREATMENT
Cell cycle regulators (p21, p53, pRb) in oligodendrocytic tumors: A study by novel tumor microarray technique
JOURNAL OF NEURO-ONCOLOGY
Thyrotropin-secreting pituitary adenomas. Clinical and biological heterogeneity and current treatment
JOURNAL OF NEURO-ONCOLOGY
Genetic basis of pituitary adenoma invasiveness: A review
JOURNAL OF NEURO-ONCOLOGY
Integration of the PRB and p53 cell cycle control pathways
JOURNAL OF NEURO-ONCOLOGY
Rb and E2F-1 regulate telomerase activity in human cancer cells
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Gain of chromosome 3 and loss of 13q are frequent alterations in pituitaryadenomas
CANCER GENETICS AND CYTOGENETICS
The developmental biology of brain tumors
ANNUAL REVIEW OF NEUROSCIENCE
Ethanol decreases expression of p21 and increases hyperphosphorylated pRb in cell lines of squamous cell carcinomas of the head and neck
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
Abbreviated cell cycle progression induced by the serine/threonine proteinphosphatase inhibitor okadaic acid at concentrations that promote neoplastic transformation
CARCINOGENESIS
Molecular abnormalities in B-cell chronic lymphocytic leukaemia
CLINICAL AND LABORATORY HAEMATOLOGY
RB1 genetic testing as a clinical service: A follow-up study
MEDICAL AND PEDIATRIC ONCOLOGY
Molecular genetics of small cell lung carcinoma
SEMINARS IN ONCOLOGY
Expression of the cell cycle proteins p2l, p27, and pRb in clear cell renal cell carcinoma and their prognostic significance
UROLOGY
Rb activation and repression of c-myc transcription precede apoptosis of human prostate epithelial cells
UROLOGY
Expression of the retinoblastoma-related gene Rb2/p130 is downregulated inatypical endometrial hyperplasia and adenocarcinoma
HUMAN PATHOLOGY
Binding of PKA-RII alpha to the adenovirus E1A(12S) oncoprotein correlateswith its nuclear translocation and an increase in PKA-dependent promoter activity
VIROLOGY
Histone deacetylase-dependent transcriptional repression by pRB in yeast occurs independently of interaction through the LXCXE binding cleft
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Promoter hypermethylation of the RB1 gene in glioblastomas
LABORATORY INVESTIGATION
Human papillomavirus E6E7-mediated adenovirus cell killing: Selectivity ofmutant adenovirus replication in organotypic cultures of human keratinocytes
JOURNAL OF VIROLOGY
Trilateral retinoblastoma variant indicative of the relevance of the retinoblastoma tumor-suppressor pathway to medulloblastomas in humans - Case report
JOURNAL OF NEUROSURGERY
Parathyroid carcinoma
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
pRb2/p130 and p107 control cell growth by multiple strategies and in association with different compartments within the nucleus
JOURNAL OF CELLULAR PHYSIOLOGY
Sp1 and kruppel-like factor family of transcription factors in cell growthregulation and cancer
JOURNAL OF CELLULAR PHYSIOLOGY
Characterization of SWI/SNF protein expression in human breast cancer celllines and other malignancies
JOURNAL OF CELLULAR PHYSIOLOGY
Nuclear membrane protein LAP2 beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less)
JOURNAL OF CELL SCIENCE
RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control
JOURNAL OF BIOLOGICAL CHEMISTRY
The ink4/arf tumor suppressors cooperate with p21(cip1/waf) in the processes of mouse epidermal differentiation, senescence, and carcinogenesis
JOURNAL OF BIOLOGICAL CHEMISTRY
RACK1 interacts with E1A and rescues E1A-induced yeast growth inhibition and mammalian cell apoptosis
JOURNAL OF BIOLOGICAL CHEMISTRY
Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes
JOURNAL OF BIOLOGICAL CHEMISTRY
Dual level inhibition of E2F-1 activity by adeno-associated virus Rep78
JOURNAL OF BIOLOGICAL CHEMISTRY
Involvement of pRB-related p107 protein in the inhibition of S phase progression in response to genotoxic stress
JOURNAL OF BIOLOGICAL CHEMISTRY
Regulation of RNA polymerase III transcription during cell cycle entry
JOURNAL OF BIOLOGICAL CHEMISTRY
The nuclear death domain protein p84N5 activates a G(2)/M cell cycle checkpoint prior to the onset of apoptosis
JOURNAL OF BIOLOGICAL CHEMISTRY
Collective inhibition of pRB family proteins by phosphorylation in cells with p16(INK4a) loss or cyclin E overexpression
JOURNAL OF BIOLOGICAL CHEMISTRY
Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecologic cancer cells
INTERNATIONAL JOURNAL OF CANCER