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Phylogenetic relationships and biochemical properties of the duplicated cytosolic and mitochondrial isoforms of malate dehydrogenase from a teleost fish, Sphyraena idiastes
JOURNAL OF MOLECULAR EVOLUTION
SDR: Structure, mechanism of action, and substrate recognition
CURRENT ORGANIC CHEMISTRY
Effect of several anions on the activity of mitochondrial malate dehydrogenase from pig heart
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
Molecular mimicry of substrate oxygen atoms by water molecules in the beta-amylase active site
PROTEIN SCIENCE
Electrostatic contributions to protein-protein interactions: Fast energetic filters for docking and their physical basis
PROTEIN SCIENCE
Structures of porcine beta-trypsin-detergent complexes: the stabilization of proteins through hydrophilic binding of polydocanol
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Substrate and cofactor binding to fluorescently labeled cytoplasmic malatedehydrogenase
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
The relative catalytic efficiency of beta-lactamase catalyzed acyl and phosphyl transfer
BIOORGANIC CHEMISTRY
A role for the alpha 113 (GH1) amino acid residue in the polymerization ofsickle hemoglobin - Evaluation of its inhibitory strength and interaction linkage with two fiber contact sites (alpha 16/23) located in the AB regionof the alpha-chain
JOURNAL OF BIOLOGICAL CHEMISTRY
Kinetic and catalytic mechanisms of protein kinases
CHEMICAL REVIEWS
Sequence determination of reduction potentials by cysteinyl hydrogen bondsand peptide dipoles in [4Fe-4S] ferredoxins
BIOPHYSICAL JOURNAL
Solution NMR characterization of the thermodynamics of the disulfide bond orientational isomerism and its effect of cluster electronic properties forthe hyperthermostable three-iron cluster ferredoxin from the archaeon Pyrococcus furiosus
BIOCHEMISTRY
Molecular modeling of the Jak3 kinase domains and structural basis for severe combined immunodeficiency
CLINICAL IMMUNOLOGY
Structure of sickle cell hemoglobin fibers probed with UV resonance Raman spectroscopy
JOURNAL OF PHYSICAL CHEMISTRY B
beta-lactamase inhibitors
DRUG RESISTANCE UPDATES
Free energy calculations: Use and limitations in predicting ligand bindingaffinities
REVIEWS IN COMPUTATIONAL CHEMISTRY, VOL 16
Polymerization of deoxy-sickle cell hemoglobin in high-phosphate buffer
JOURNAL OF STRUCTURAL BIOLOGY
The atomic resolution structure of bucandin, a novel toxin isolated from the Malayan krait, determined by direct methods
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Protein structure alignment using a genetic algorithm
PROTEINS-STRUCTURE FUNCTION AND GENETICS
Metallocarboxypeptidases and their protein inhibitors - Structure, function and biomedical properties
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
How does light regulate chloroplast enzymes? Structure-function studies ofthe ferredoxin/thioredoxin system
QUARTERLY REVIEWS OF BIOPHYSICS
Protein-protein interaction revealed by NMR T-2 relaxation experiments: The lipoyl domain and E1 component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
JOURNAL OF MOLECULAR BIOLOGY
FAD insertion is essential for attaining the assembly competence of the dihydrolipoamide dehydrogenase (E3) monomer from Escherichia coli
JOURNAL OF BIOLOGICAL CHEMISTRY
Purification of the 45 kDa, membrane bound NADH dehydrogenase of Escherichia coli (NDH-2) and analysis of its interaction with ubiquinone analogues
FEBS LETTERS
Use of protein engineering methods for studies of calcium-binding proteins
BIOFIZIKA
Insights into the molecular relationships between malate and lactate dehydrogenases: Structural and biochemical properties of monomeric and dimeric intermediates of a mutant of tetrameric L-[LDH-like] malate dehydrogenase from the halophilic archaeon Holorcula marismortui
BIOCHEMISTRY
Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase
BIOCHEMISTRY
Diversity and origin of alternative NADH : ubiquinone oxidoreductases
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Residue determinants and sequence analysis of cold-adapted trypsins
EXTREMOPHILES
The reactivity of beta-lactams, the mechanism of catalysis and the inhibition of beta-lactamases
CURRENT PHARMACEUTICAL DESIGN
Structural and mechanistic aspects of evolution of beta-lactamases and penicillin-binding proteins
CURRENT PHARMACEUTICAL DESIGN
Melatonin biosynthesis: The structure of serotonin N-acetyltransferase at 2.5 angstrom resolution suggests a catalytic mechanism
MOLECULAR CELL
Site-directed mutagenesis of human dihydrolipoamide dehydrogenase: Role oflysine-54 and glutamate-192 in stabilizing the thiolate-FAD intermediate
PROTEIN EXPRESSION AND PURIFICATION
Chloroplast NADP-malate dehydrogenase: structural basis of light-dependentregulation of activity by thiol oxidation and reduction
STRUCTURE WITH FOLDING & DESIGN
Evaluation and improvement of multiple sequence methods for protein secondary structure prediction
PROTEINS-STRUCTURE FUNCTION AND GENETICS
Raman difference studies of protein-nucleic acid interactions
JOURNAL OF RAMAN SPECTROSCOPY
Analysis of a concerted mechanism in beta-lactam enzymatic hydrolysis. A quantum mechanics/molecular mechanics study
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
Inhibition of beta(S)-chain dependent polymerization by synergistic complementation of contact site perturbations of alpha-chain: application of semisynthetic chimeric alpha-chains
PROTEIN ENGINEERING
The beta-lactamase cycle: a tale of selective pressure and bacterial ingenuity
NATURAL PRODUCT REPORTS
Modeling beta-lactam interactions in aqueous solution through combined quantum mechanics-molecular mechanics methods
JOURNAL OF COMPUTATIONAL CHEMISTRY
Poisson-Boltzmann model studies of molecular electrostatic properties of the cAMP-dependent protein kinase
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
Conformational diversity of catalytic cores of protein kinases
PHARMACOLOGY & THERAPEUTICS
Calcium-binding proteins
ADVANCES IN INORGANIC CHEMISTRY, VOL 46
A natural grouping of motifs with an aspartate or asparagine residue forming two hydrogen bonds to residues ahead in sequence: Their occurrence at alpha-helical N termini and in other situations
JOURNAL OF MOLECULAR BIOLOGY
Solution-active structural alterations in liganded hemoglobins C (beta 6 Glu -> Lys) and S (beta 6 Glu -> Val)
JOURNAL OF BIOLOGICAL CHEMISTRY
Pyruvate dehydrogenase from Azotobacter vinelandii - Properties of the N-terminally truncated enzyme
EUROPEAN JOURNAL OF BIOCHEMISTRY
600 ps molecular dynamics reveals stable substructures and flexible hinge points in cAMP dependent protein kinase
BIOPOLYMERS
Determinants of ligand binding to cAMP-dependent protein kinase
BIOCHEMISTRY
Probing the affinity and specificity of yeast alcohol dehydrogenase I for coenzymes
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
CONFORMATION OF THE FLAVIN ADENINE-DINUCLEOTIDE COFACTOR FAD IN DNA-PHOTOLYASE - A MOLECULAR-DYNAMICS STUDY
JOURNAL OF MOLECULAR MODELING
CONFORMATIONAL-CHANGES IN FMETHBS PROBED WITH UV RESONANCE RAMAN AND FLUORESCENCE SPECTROSCOPIC METHODS
JOURNAL OF PHYSICAL CHEMISTRY B
THE MECHANISM OF CATALYSIS AND THE INHIBITION OF BETA-LACTAMASES
Chemical communications
Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B
IMMUNITY
CATALYTIC TRIADS AND THEIR RELATIVES
Trends in biochemical sciences
Structures of EF-hand Ca2+-binding proteins: Diversity in the organization, packing and response to Ca2+ binding
BIOMETALS
MOLECULAR MECHANISMS FOR THE CONVERSION OF ZYMOGENS TO ACTIVE PROTEOLYTIC-ENZYMES
Protein science
CRYSTALLIZATION AND PRELIMINARY-X-RAY ANALYSIS OF PIG E3, LIPOAMIDE DEHYDROGENASE
Acta crystallographica. Section D, Biological crystallography
1.85 A RESOLUTION STRUCTURE OF THE ZINC(II) BETA-LACTAMASE FROM BACILLUS-CEREUS
Acta crystallographica. Section D, Biological crystallography
FOLDING MOTIFS INDUCED AND STABILIZED BY DISTINCT CYSTINE FRAMEWORKS
Protein engineering (Print)
CATALYTIC PROPERTIES OF CLASS-A BETA-LACTAMASES - EFFICIENCY AND DIVERSITY
Biochemical journal
MALATE-DEHYDROGENASE - DISTRIBUTION, FUNCTION AND PROPERTIES
General physiology and biophysics
THE PYRUVATE-DEHYDROGENASE MULTIENZYME COMPLEX FROM GRAM-NEGATIVE BACTERIA
Biochimica et biophysica acta. Protein structure and molecular enzymology
KINSHIP AND DIVERSIFICATION OF BACTERIAL PENICILLIN-BINDING PROTEINS AND BETA-LACTAMASES
Antimicrobial agents and chemotherapy
CONSERVED WATER-MOLECULES CONTRIBUTE TO THE EXTENSIVE NETWORK OF INTERACTIONS AT THE ACTIVE-SITE OF PROTEIN-KINASE-A
Proceedings of the National Academy of Sciences of the United Statesof America
ELUCIDATION OF THE MODE OF INTERACTION OF THERMOLYSIN WITH A PROTEINACEOUS METALLOPROTEINASE INHIBITOR, SMPI, BASED ON A MODEL COMPLEX STRUCTURE AND A STRUCTURAL DYNAMICS ANALYSIS
Journal of Molecular Biology
STEREOCHEMICAL PUNCTUATION MARKS IN PROTEIN STRUCTURES - GLYCINE AND PROLINE-CONTAINING HELIX STOP SIGNALS
Journal of Molecular Biology
NOVEL RUBREDOXIN MODEL TETRATHIOLATO IRON(II) AND COBALT(II) COMPLEXES CONTAINING INTRAMOLECULAR SINGLE AND DOUBLE NH-CENTER-DOT-CENTER-DOT-CENTER-DOT-S HYDROGEN-BONDS
Inorganic chemistry
CONSERVED SUPERSECONDARY STRUCTURAL MOTIF IN NAD-DEPENDENT DEHYDROGENASES
FEBS letters
Expression of genes encoding the E2 and E3 components of the Bacillus stearothermophilus pyruvate dehydrogenase complex and the stoichiometry of subunit interaction in assembly in vitro
EUROPEAN JOURNAL OF BIOCHEMISTRY
ANALYSIS OF THE STABILITY OF HEMOGLOBIN-S DOUBLE STRANDS
Biophysical journal
THERMOPHILIC XYLANASE FROM THERMOMYCES-LANUGINOSUS - HIGH-RESOLUTION X-RAY STRUCTURE AND MODELING STUDIES
Biochemistry (Easton)
SPONTANEOUS INACTIVATION OF HUMAN TRYPTASE INVOLVES CONFORMATIONAL-CHANGES CONSISTENT WITH CONVERSION OF THE ACTIVE-SITE TO A ZYMOGEN-LIKE STRUCTURE
Biochemistry
CHARGE AND SOLVATION EFFECTS IN ANION RECOGNITION CENTERS - AN INQUIRY EXPLOITING REACTIVE ARGININES
Biochemistry
KINETIC ANALYSES OF MUTATIONS IN THE GLYCINE-RICH LOOP OF CAMP-DEPENDENT PROTEIN-KINASE
Biochemistry
ROLE OF THE OMEGA-LOOP IN THE ACTIVITY, SUBSTRATE-SPECIFICITY, AND STRUCTURE OF CLASS-A BETA-LACTAMASE
Biochemistry
Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly of a composite ligand-binding site
BIOCHEMISTRY
ATOMIC-STRUCTURE OF THE TRYPSIN-AERUGINOSIN 98-B COMPLEX
Journal of the American Chemical Society
STRUCTURE (1.3 ANGSTROM) AND CHARGE STATES OF A RIBONUCLEASE-A URIDINE VANADATE COMPLEX - IMPLICATIONS FOR THE PHOSPHATE ESTER HYDROLYSIS MECHANISM
Journal of the American Chemical Society
A TETRAMERIC MODEL OF THE DIHYDROLIPOAMIDE DEHYDROGENASE COMPONENT OFTHE PYRUVATE-DEHYDROGENASE COMPLEX - CONSTRUCTION AND EVALUATION BY MOLECULAR MODELING TECHNIQUES
JOURNAL OF MOLECULAR MODELING
2-OXO ACID DEHYDROGENASE MULTIENZYME COMPLEXES - THE CENTRAL ROLE OF THE LIPOYL DOMAIN
Biological chemistry
EVOLUTION AND DISSEMINATION OF BETA-LACTAMASES ACCELERATED BY GENERATIONS OF BETA-LACTAM ANTIBIOTICS
Clinical infectious diseases
STRUCTURAL AND SEQUENCE-BASED CLASSIFICATION OF GLYCOSIDE HYDROLASES
Current opinion in structural biology
DEFICIENCY OF DIHYDROLIPOAMIDE DEHYDROGENASE DUE TO 2 MUTANT ALLELES (E340K AND G101DEL) - ANALYSIS OF A FAMILY AND PRENATAL TESTING
Biochimica et biophysica acta. Molecular basis of disease
PENICILLIN-BINDING PROTEINS - WALL PEPTIDOGLYCAN ASSEMBLY AND RESISTANCE TO PENICILLIN - FACTS, DOUBTS AND HOPES
International journal of antimicrobial agents
X-RAY STRUCTURE OF A RIBONUCLEASE-A-URIDINE-VANADATE COMPLEX AT 1.3-ANGSTROM RESOLUTION
Acta crystallographica. Section D, Biological crystallography
STRUCTURAL TREES FOR PROTEIN SUPERFAMILIES
Proteins
[3FE-4S][--][4FE-4S] CLUSTER INTERCONVERSION IN DESULFOVIBRIO-AFRICANUS FERREDOXIN-III - PROPERTIES OF AN ASP(14)-]CYS MUTANT
Biochemical journal
THE 3-DIMENSIONAL STRUCTURE OF HUMAN PROCARBOXYPEPTIDASE A2 - DECIPHERING THE BASIS OF THE INHIBITION, ACTIVATION AND INTRINSIC ACTIVITY OFTHE ZYMOGEN
EMBO journal
SWISS-MODEL AND THE SWISS-PDBVIEWER - AN ENVIRONMENT FOR COMPARATIVE PROTEIN MODELING
Electrophoresis
RECEPTOR-SITE AND STEREOSPECIFICITY OF DIHYDROLIPOAMIDE DEHYDROGENASEFOR R-LIPOAMIDE AND S-LIPOAMIDE - A MOLECULAR MODELING STUDY
Journal of biotechnology
NOVEL STRUCTURAL MOTIFS IN ALPHA-HELICAL PROTEINS
Bioorganiceskaa himia
A LINK BETWEEN PROTEIN-STRUCTURE AND ENZYME-CATALYZED HYDROGEN TUNNELING
Proceedings of the National Academy of Sciences of the United Statesof America
MOLECULAR EVOLUTIONARY ANALYSIS OF THE THIAMINE-DIPHOSPHATE-DEPENDENTENZYME, TRANSKETOLASE
Journal of molecular evolution
MODELING PROTEIN DOCKING USING SHAPE COMPLEMENTARITY, ELECTROSTATICS AND BIOCHEMICAL INFORMATION
Journal of Molecular Biology
ANALYSIS OF PROTEIN-PROTEIN INTERACTION SITES USING SURFACE PATCHES
Journal of Molecular Biology
PREDICTION OF PROTEIN-PROTEIN INTERACTION SITES USING PATCH ANALYSIS
Journal of Molecular Biology
MOLECULAR-STRUCTURE OF THE LIPOAMIDE DEHYDROGENASE DOMAIN OF A SURFACE-ANTIGEN FROM NEISSERIA-MENINGITIDIS
Journal of Molecular Biology
THE 3-DIMENSIONAL STRUCTURE OF FLAVODOXIN REDUCTASE FROM ESCHERICHIA-COLI AT 1.7-ANGSTROM RESOLUTION
Journal of Molecular Biology
DEVELOPMENT AND VALIDATION OF A GENETIC ALGORITHM FOR FLEXIBLE DOCKING
Journal of Molecular Biology
SITE-DIRECTED MUTAGENESIS OF GLUTAMATE-166 IN 2 BETA-LACTAMASES - KINETIC AND MOLECULAR MODELING STUDIES
The Journal of biological chemistry