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La ricerca find articoli where soggetti phrase all words 'RECOMBINANT HIRUDIN' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 388 riferimenti
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    1. Stone, D; Phaneuf, M; Sivamurthy, N; LoGerfo, FW; Quist, WC
      A biologically active VEGF construct in vitro: Implications for bioengineering-improved prosthetic vascular grafts

      JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
    2. Manfredi, JA; Wall, RP; Sane, DC; Braden, GA
      Lepirudin as a safe alternative for effective anticoagulation in patients with known heparin-induced thrombocytopenia undergoing percutaneous coronary intervention: Case reports

      CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
    3. Levin, LA; Bergqvist, D
      Cost effectiveness of desirudin compared with a low molecular weight heparin in the prevention of deep vein thrombosis after total hip replacement surgery

      PHARMACOECONOMICS
    4. Deitcher, SR
      Heparin-induced thrombocytopenia: Pathogenesis, management, and prevention

      FORMULARY
    5. Grassegger, A; Fritsch, P; Reider, N
      Delayed-type hypersensitivity and cross-reactivity to heparins and danaparoid: A prospective study

      DERMATOLOGIC SURGERY
    6. Van Aken, H; Bode, C; Darius, H; Diehm, C; Encke, M; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schror, K; Schulte, KL; Tebbe, U
      Anticoagulation: The present and future

      CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
    7. Demir, M; Iqbal, O; Untch, B; Hoppensteadt, DA; Gaikwad, BS; Fareed, J
      Ecarin clotting time is sensitive to heparinoids: Comparison of two different techniques

      CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
    8. Axelrod, DA; Wakefield, TW
      Future directions in antithrombotic therapy: Emphasis on venous thromboembolism

      JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
    9. Dager, WE; White, RH
      Use of lepirudin in patients with heparin-induced thrombocytopenia and renal failure requiring hemodialysis

      ANNALS OF PHARMACOTHERAPY
    10. Kondo, LM; Wittkowsky, AK; Wiggins, BS
      Argatroban for prevention and treatment of thromboembolism in heparin-induced thrombocytopenia

      ANNALS OF PHARMACOTHERAPY
    11. Hoffmann, JJML; Janssen, WCM
      Comparison of three methods for measuring PEG-hirudin in blood

      BLOOD COAGULATION & FIBRINOLYSIS
    12. Sheffield, WP; Smith, IJ; Syed, S; Bhakta, V
      Prolonged in vivo anticoagulant activity of a hirudin-albumin fusion protein secreted from Pichia pastoris

      BLOOD COAGULATION & FIBRINOLYSIS
    13. Chern, I; Sharma, A; Dennis, D
      Concurrent use of reteplase and lepirudin in the treatment of acute anterior wall myocardial infarction

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    14. Weitz, JI
      New anticoagulant drugs

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    15. Chi, LG; Mertz, TE; Rogers, KL; Janiczek, N; Peng, YW; Saganek, L; Bousley, RF; Juneau, PL; Uprichard, ACG; Gallagher, KP
      Antithrombotic effect of LB-30057 (CI-1028), a new synthetic thrombin inhibitor, in a rabbit model of thrombosis: Comparison with inogatran

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    16. Andreescu, ACM; Cushman, M; Hammond, JM; Wood, ME
      Trousseau's syndrome treated with long-term subcutaneous lepirudin (case report and review of the literature)

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    17. Salmi, L; Leroy-Matheron, C; LeBesnerais, P; Rosanval, O; Duvaldestin, P; Gouault-Heilmann, M
      Coronary bypass with sodic danaparold for value replacement during thrombocytopenia due to type II heparin.

      ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION
    18. Billett, HH
      Direct and indirect antithrombins - Heparins, low molecular weight heparins, heparinoids, and hirudin

      CLINICS IN GERIATRIC MEDICINE
    19. Mudaliar, JH; Liem, TK; Nichols, WK; Spadone, DP; Silver, D
      Lepirudin is a safe and effective anticoagulant for patients with heparin-associated antiplatelet antibodies

      JOURNAL OF VASCULAR SURGERY
    20. Jakobs, D
      Heparin-induced thrombocytopenia, left ventricular thrombus and cerebral embolism in the course of myocardial infarction

      MEDIZINISCHE KLINIK
    21. Hein, OV; von Heymann, C; Lipps, M; Ziemer, S; Ronco, C; Neumayer, HH; Morgera, S; Welte, M; Kox, WJ; Spies, C
      Hirudin versus heparin for anticoagulation in continuous renal replacementtherapy

      INTENSIVE CARE MEDICINE
    22. Chong, BH; Gallus, AS; Cade, JF; Magnani, H; Manoharan, A; Oldmeadow, M; Arthur, C; Rickard, K; Gallo, J; Lloyd, J; Seshadri, P; Chesterman, CN
      Prospective randomised open-label comparison of danaparoid with dextran 70in the treatment of heparin-induced thrombocytopaenia with thrombosis - A clinical outcome study

      THROMBOSIS AND HAEMOSTASIS
    23. Warkentin, TE
      Heparin-induced thrombocytopenia: Yet another treatment paradox?

      THROMBOSIS AND HAEMOSTASIS
    24. Farner, B; Eichler, P; Kroll, H; Greinacher, A
      A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia

      THROMBOSIS AND HAEMOSTASIS
    25. Huhle, G; Liebe, V; Hudek, R; Heene, DL
      Anti-r-hirudin antibodies reveal clinical relevance through direct functional inactivation of r-hirudin or prolongation of r-hirudin's plasma halflife

      THROMBOSIS AND HAEMOSTASIS
    26. Bi, Q; Zhang, JS; Huang, YX; Su, HJ; Zhou, XW; Zhu, SG
      Construction, expression, and characterization of recombinant hirudin in Escherichia coli

      APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
    27. Chuang, P; Parikh, C; Reilly, RF
      A case review: Anticoagulation in hemodialysis patients with heparin-induced thrombocytopenia

      AMERICAN JOURNAL OF NEPHROLOGY
    28. Markwardt, F
      Development of direct thrombin inhibitors in comparison with glycosaminoglycans

      SEMINARS IN THROMBOSIS AND HEMOSTASIS
    29. Prisco, D; Falciani, M; Antonucci, E; Gensini, GF
      Hirudins for prophylaxis and treatment of venous thromboembolism

      SEMINARS IN THROMBOSIS AND HEMOSTASIS
    30. Severin, T; Sutor, AH
      Heparin-induced thrombocytopenia in pediatrics

      SEMINARS IN THROMBOSIS AND HEMOSTASIS
    31. Lee, AYY
      Treatment of venous thromboembolism in cancer patients

      THROMBOSIS RESEARCH
    32. Wille-Jorgensen, P
      The potential role of new therapies in deep-vein thrombosis prophylaxis

      SEMINARS IN HEMATOLOGY
    33. Faaij, RA; van Griensven, JMT; Schoemaker, RC; Goggin, T; Guenzi, A; Kroon, JM; Burggraaf, J; Cohen, AF
      The effect of warfarin on the pharmacokinetics and pharmacodynamics of napsagatran in healthy male volunteers

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    34. Eriksson, BI; Bauer, KA; Lassen, MR; Turpie, AGG
      Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery.

      NEW ENGLAND JOURNAL OF MEDICINE
    35. Rocha, E; Panizo, C; Lecumberri, R
      Direct thrombin inhibitors: their role in the treatment of arterial and venous thrombosis

      MEDICINA CLINICA
    36. Echtenacher, B; Weigl, K; Lehn, N; Mannel, DN
      Tumor necrosis factor-dependent adhesions as a major protective mechanism early in septic peritonitis in mice

      INFECTION AND IMMUNITY
    37. Kleinschmidt, S; Mertzlufft, F; Bach, F; Plinkert, RK
      Heparin-induced thrombocytopenia (HIT) - Problem and their importance for ENT medicine

      HNO
    38. Salzet, M
      Anticoagulants and inhibitors of platelet aggregation derived from leeches

      FEBS LETTERS
    39. Lewis, BE; Wallis, DE; Berkowitz, SD; Matthai, WH; Fareed, J; Walenga, JM; Bartholomew, J; Sham, R; Lerner, RG; Zeigler, ZR; Rustagi, PK; Jang, IK; Rifkin, SD; Moran, J; Hursting, MJ; Kelton, JG
      Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia

      CIRCULATION
    40. Greinacher, A; Lubenow, N
      Recombinant hirudin in clinical practice - Focus on lepirudin

      CIRCULATION
    41. Heit, JA; Colwell, CW; Francis, CW; Ginsberg, JS; Berkowitz, SD; Whipple, J; Peters, G
      Comparison of the oral direct thrombin inhibitor ximelagatran with enoxaparin as prophylaxis against venous thromboembolism after total knee replacement - A phase 2 dose-finding study

      ARCHIVES OF INTERNAL MEDICINE
    42. Konkle, BA; Bauer, TL; Arepally, G; Cines, DB; Poncz, M; McNulty, S; Edie, RN; Mannion, JD
      Heparin-induced thrombocytopenia: Bovine versus porcine heparin in cardiopulmonary bypass surgery

      ANNALS OF THORACIC SURGERY
    43. Aouifi, A; Blanc, P; Piriou, V; Bastien, OH; Ffrench, P; Hanss, M; Lehot, JJ
      Cardiac surgery with cardiopulmonary bypass in patients with type II heparin-induced thrombocytopenia

      ANNALS OF THORACIC SURGERY
    44. Koster, A; Kulucka, M; Bach, F; Meyer, O; Fischer, T; Mertzlufft, F; Loebe, M; Hetzer, R; Kuppe, H
      Anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia type II and renal impairment using heparin and the platelet glycoprotein IIb-IIIa antagonist tirofiban

      ANESTHESIOLOGY
    45. Despotis, GJ; Hogue, CW; Saleem, R; Bigham, M; Skubas, N; Apostolidou, I; Qayum, A; Joist, JH
      The relationship between hirudin and activated clotting time: Implicationsfor patients with heparin-induced thrombocytopenia undergoing cardiac surgery

      ANESTHESIA AND ANALGESIA
    46. Sun, Y; Greilich, PE; Wilson, SIO; Jackson, MR; Whitten, CW
      The use of lepirudin for anticoagulation in patients with heparin-induced thrombocytopenia during major vascular surgery

      ANESTHESIA AND ANALGESIA
    47. Horne, MK
      The dark side of deep venous thrombosis: The failure of anticoagulation

      AMERICAN JOURNAL OF MEDICINE
    48. Levy, JP
      Novel intravenous antithrombins

      AMERICAN HEART JOURNAL
    49. Kumura, T; Hino, M; Yamane, T; Tatsumi, N
      Hirudin as an anticoagulant for both haematology and chemistry tests

      JOURNAL OF AUTOMATED METHODS & MANAGEMENT IN CHEMISTRY
    50. Reilly, MP; Weiss, R; Askenase, A; Tuite, C; Soulen, M; Mohler, ER
      Hirudin therapy during thrombolysis for venous thrombosis in heparin-induced thrombocytopenia

      VASCULAR MEDICINE
    51. Gordon, MB; Beckman, JA
      Successful anticoagulation with hirudin in a patient with mesenteric venous thrombosis and multiple coagulation abnormalities

      VASCULAR MEDICINE
    52. Basu, S; Larsson, A; Mattsson, C; Eriksson, O; Kiiski, R; Nordgren, A; Eriksson, M
      Effects of melagatran, a novel direct thrombin inhibitor, during experimental septic shock

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    53. Tardey-Poncet, B; Tardy, B
      Heparin-induced thrombocytopenia - Minimising the risks in the elderly patient

      DRUGS & AGING
    54. Hoffmann, JN; Vollmar, B; Inthorn, D; Schildberg, FW; Menger, MD
      The thrombin antagonist hirudin fails to inhibit endotoxin-induced leukocyte/endothelial cell interaction and microvascular perfusion failure

      SHOCK
    55. Pamboukian, SV; Ignaszewski, AP; Ross, HJ
      Management strategies for heparin-induced thrombocytopenia in heart-transplant candidates: Case report and review of the literature

      JOURNAL OF HEART AND LUNG TRANSPLANTATION
    56. Koster, A; Hansen, R; Grauhan, O; Hausmann, H; Bauer, M; Hetzer, R; Kuppe, H; Mertzlufft, F
      Hirudin monitoring using the TAS ecarin clotting time in patients with heparin-induced thrombocytopenia type II

      JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
    57. Koster, A; Crystal, GJ; Kuppe, H; Mertzlufft, F
      Acute heparin-induced thrombocytopenia type II during cardiopulmonary bypass

      JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
    58. Mertzlufft, F; Kuppe, H; Koster, A
      Management of urgent high-risk cardiopulmonary bypass in patients with heparin-induced thrombocytopenia type II and coexisting disorders of renal function: Use of heparin and epoprostenol combined with on-line monitoring of platelet function

      JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
    59. Xue, MZ; Fenton, JW; Shen, GX
      Hirulog-1 reduces expression of platelet-derived growth factor in neointima of rat carotid artery induced by balloon catheter injury

      JOURNAL OF VASCULAR RESEARCH
    60. Koster, A; Meyer, O; Hausmann, H; Kuppe, H; Hetzer, R; Mertzlufft, F
      In vitro cross-reactivity of danaparoid sodium in patients with heparin-induced thrombocytopenia type II undergoing cardiovascular surgery

      JOURNAL OF CLINICAL ANESTHESIA
    61. Warkentin, TE
      Heparin-induced thrombocytopenia and its treatment

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    62. Vermeer, F; Vahanian, A; Fels, PW; Besse, P; Muller, E; Van de Werf, F; Fitzgerald, D; Darius, H; Puel, J; Garrigou, D; Simoons, ML
      Argatroban and alteplase in patients with acute myocardial infarction: TheARGAMI study

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    63. Becker, RC
      Hirudin-based anticoagulant strategies for patients with suspected heparin-induced thrombocytopenia undergoing percutaneous coronary interventions and bypass grafting

      JOURNAL OF THROMBOSIS AND THROMBOLYSIS
    64. Gietz, U; Arvinte, T; Haner, M; Aebi, U; Merkle, HP
      Formulation of sustained release aqueous Zn-hirudin suspensions

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    65. Komatsu, Y; Hayashi, H
      Most clot-bound thrombin activity is inhibited by plasma antithrombin during clot aging, but a very small fraction survives

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    66. Ouseph, R; Ward, RA
      Anticoagulation for intermittent hemodialysis

      SEMINARS IN DIALYSIS
    67. Huhle, G; Geberth, M; Hoffmann, U; Heene, DL; Harenberg, J
      Management of heparin-associated thrombocytopenia in pregnancy with subcutaneous r-hirudin

      GYNECOLOGIC AND OBSTETRIC INVESTIGATION
    68. Friederich, PW; Keller, TT; Biemond, BJ; Peters, RJG; Hornberger, W; Buller, HR; Levi, M
      Successful attenuation of venous thrombus growth in rabbits after the administration of a novel oral thrombin inhibitor

      THROMBOSIS AND HAEMOSTASIS
    69. Berry, CN; Lunven, C; Lecoffre, C; Lainee, P; O'Connor, SE; Andre, F; Roger, B; Garrigou-Gadenne, D; Rouchouse, A; Roome, NO; Vivan, N
      Anticoagulant activity and pharmacokinetic properties of a sub-cutaneouslyadministered mixed micellar formulation of argatroban in experimental animals

      THROMBOSIS AND HAEMOSTASIS
    70. Berry, CN; Visconte, C; Lecoffre, C; Lochot, S; Girard, D
      Activity of a sub-cutaneously administered novel mixed micellar formulation of argatroban in rat and rabbit models of venous thrombosis

      THROMBOSIS AND HAEMOSTASIS
    71. Zeymer, U; Neuhaus, KL
      Thrombolysis and percutaneous transluminal coronary angioplasty in patients with acute myocardial infarction

      ZEITSCHRIFT FUR KARDIOLOGIE
    72. Wittkowsky, AK; Kondo, LM
      Lepirudin dosing in dialysis-dependent renal failure

      PHARMACOTHERAPY
    73. Richardson, JL; Kroger, B; Hoeffken, W; Sadler, JE; Pereira, P; Huber, R; Bode, W; Fuentes-Prior, P
      Crystal structure of the human alpha-thrombin-haemadin complex: an exositeII-binding inhibitor

      EMBO JOURNAL
    74. Wille-Jorgensen, P
      New therapeutic options in DVT prophylaxis

      ORTHOPEDICS
    75. Poschel, KA; Bucha, E; Esslinger, HU; Nortersheuser, P; Jansa, U; Schindler, S; Nowak, G; Stein, G
      Pharmacodynamics and pharmacokinetics of polyethylene glycol-hirudin in patients with chronic renal failure

      KIDNEY INTERNATIONAL
    76. Huhle, G; Hoffmann, U; Hoffmann, I; Liebe, V; Harenberg, JF; Heene, DL
      A new therapeutic option by subcutaneous recombinant hirudin in patients with heparin-induced thrombocytopenia type II: A pilot study

      THROMBOSIS RESEARCH
    77. Song, XH; Huhle, G; Wang, LC; Harenberg, J
      Quantitative determination of PEG-hirudin in human plasma using a competitive enzyme-linked immunosorbent assay

      THROMBOSIS RESEARCH
    78. van Zyl, WB; Pretorius, GHJ; Lamprecht, S; Roodt, JP; Kotze, HF
      PLATSAK, a potent antithrombotic and fibrinolytic protein, inhibits arterial and venous thrombosis in a baboon model

      THROMBOSIS RESEARCH
    79. Suzuki, S; Matsuo, T; Kobayashi, H; Matsuo, M; Shimamo, C; Koide, M; Sakamoto, S
      Antithrombotic treatment (argatroban vs. heparin) in coronary angioplasty in angina pectoris: Effects on inflammatory, hemostatic, and endothelium-derived parameters

      THROMBOSIS RESEARCH
    80. Lubenow, N; Eichler, P; Albrecht, D; Carlsson, LE; Kothmann, J; Rossocha, WR; Hahn, M; Quitmann, H; Greinacher, A
      Very low platelet counts in post-transfusion purpura falsely diagnosed as heparin-induced thrombocytopenia: Report of four cases and review of literature

      THROMBOSIS RESEARCH
    81. Leblond, L; Grouix, B; Boudreau, C; Yang, Q; Siddiqui, MA; Winocour, PD
      In vitro and in vivo properties of bicyclic lactam inhibitors: A novel class of low molecular weight peptidomimetic thrombin inhibitors

      THROMBOSIS RESEARCH
    82. Lindhoff-Last, E; Piechottka, GP; Rabe, F; Bauersachs, R
      Hirudin determination in plasma can be strongly influenced by the prothrombin level

      THROMBOSIS RESEARCH
    83. Pakala, R; Liang, CT; Benedict, CR
      Inhibition of arterial thrombosis by a peptide ligand of the thrombin receptor

      THROMBOSIS RESEARCH
    84. Schneider, T; Heuer, B; Deller, A; Boesken, WH
      Continuous haemofiltration with r-hirudin (lepirudin) as anticoagulant in a patient with heparin induced thrombocytopenia (HIT II)

      WIENER KLINISCHE WOCHENSCHRIFT
    85. Salzet, M; Chopin, V; Baert, JL; Matias, I; Malecha, J
      Theromin, a novel leech thrombin inhibitor

      JOURNAL OF BIOLOGICAL CHEMISTRY
    86. Matheson, AJ; Goa, KL
      Desirudin - A review of its use in the management of thrombotic disorders

      DRUGS
    87. Peter, K; Graeber, J; Kipriyanov, S; Zewe-Welschof, M; Runge, MS; Kubler, W; Little, M; Bode, C
      Construction and functional evaluation of a single-chain antibody fusion protein with fibrin targeting and thrombin inhibition after activation by factor Xa

      CIRCULATION
    88. Gandossi, E; Lunven, C; Berry, CN
      Role of clot-associated (-derived) thrombin in cell proliferation induced by fibrin clots in vitro

      BRITISH JOURNAL OF PHARMACOLOGY
    89. Harenberg, J; Hoffmann, U; Huhle, G; Song, XH; Wang, LC
      Treatment of an acute flush reaction caused by subcutaneous r-hirudin withpegylated hirudin

      BRITISH JOURNAL OF HAEMATOLOGY
    90. Eichler, P; Friesen, HJ; Lubenow, N; Jaeger, B; Greinacher, A
      Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: incidence, effects on aPTT, and clinical relevance

      BLOOD
    91. Greinacher, A; Eichler, P; Lubenow, N; Kwasny, H; Luz, M
      Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatmentwith lepirudin and its therapeutic aPTT range

      BLOOD
    92. Pernerstorfer, T; Hollenstein, U; Hansen, JB; Stohlawetz, P; Eichler, HG; Handler, S; Speiser, W; Jilma, B
      Lepirudin blunts endotoxin-induced coagulation activation

      BLOOD
    93. Fabris, F; Ahmad, S; Cella, G; Jeske, WP; Walenga, JM; Fareed, J
      Pathophysiology of heparin-induced thrombocytopenia clinical and diagnostic implications - A review

      ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
    94. Maeno, T; Tano, Y; Mano, T; Takenaka, H
      Argatroban inhibits intraocular fibrin formation after vitrectomy in rabbits

      ARCHIVES OF OPHTHALMOLOGY
    95. Follis, F; Schmidt, CA
      Cardiopulmonary bypass in patients with heparin-induced thrombocytopenia and thrombosis

      ANNALS OF THORACIC SURGERY
    96. Frederiksen, JW
      Cardiopulmonary bypass in humans: Bypassing unfractionated heparin

      ANNALS OF THORACIC SURGERY
    97. Koster, A; Pasic, M; Bauer, M; Kuppe, H; Hetzer, R
      Hirudin as anticoagulant for cardiopulmonary bypass: Importance of preoperative renal function

      ANNALS OF THORACIC SURGERY
    98. Eikelboom, JW; Ginsburg, JS
      Preventing thromboembolic complications in older orthopaedic surgery patients - Interventions and outcomes

      DRUGS & AGING
    99. Weltermann, A; Wolzt, M; Petersmann, K; Czerni, C; Graselli, U; Lechner, K; Kyrle, PA
      Large amounts of vascular endothelial growth factor at the site of hemostatic plug formation in vivo

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    100. Dickneite, G; Leithauser, B
      Influence of antithrombin III on coagulation and inflammation in porcine septic shock

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY


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Documento generato il 02/06/20 alle ore 21:40:55