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Identification and characterization of mouse bone marrow stromal cell lines immortalized by temperature-sensitive SV40 T antigen: Supportive activityfor osteoclast differentiation
BONE
Transforming growth factor-beta 1 (TGF-beta) stimulates the osteoclast-forming potential of peripheral blood hematopoietic precursors in a lymphocyte-rich microenvironment
BONE
Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappa B ligand in generation of osteoclasts in stromal cell-depletedrat bone marrow cell culture
BONE
Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone
BONE
The endocytic pathway: A mosaic of domains
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Bone loss - Therapeutic approaches for preventing bone loss in inflammatory arthritis
ARTHRITIS RESEARCH
Peptide immunotherapy
NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
Combinatorial chemistry: A tool for the discovery of new catalysts
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
Virtual screening: An effective tool for lead structure discovery?
CURRENT PHARMACEUTICAL DESIGN
Bioadhesion and the dewetting transition
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE IV PHYSIQUE ASTROPHYSIQUE
Acute and chronic smooth muscle cell apoptosis after mechanical vascular injury can occur independently of the Fas-death pathway
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
P53, caspase 8, and regulation of apoptosis after ionizing radiation
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Chemosensitivity of TEL-AML1 fusion transcript positive acute lymphoblastic leukemia cells
LEUKEMIA & LYMPHOMA
Apoptosis and the response to anticancer therapy
CURRENT OPINION IN ONCOLOGY
Neuroepithelial bodies in mammalian lung express functional serotonin type3 receptor
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Virological and immunological connotations of apoptotic and anti-apoptoticforces in neoplasia
INTERNATIONAL JOURNAL OF ONCOLOGY
Bcl-2 modulates Fas-mediated apoptosis in human renal cell carcinoma cell lines
INTERNATIONAL JOURNAL OF ONCOLOGY
The physical chemistry of ligand-receptor binding identifies some limitations to the analysis of receptor images
NUCLEAR MEDICINE AND BIOLOGY
Synthesis and preliminary evaluation of a carbon-11-labeled adenosine transporter blocker [C-11]KF21652
NUCLEAR MEDICINE AND BIOLOGY
The role of peripheral T-cell deletion in transplantation tolerance
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
Biochemical engineering of the N-acyl side chain of sialic acid: biological implications
GLYCOBIOLOGY
Degeneracy and additional alloreactivity of drug-specific human alpha beta(+) T cell clones
INTERNATIONAL IMMUNOLOGY
Transactivation-deficient p73 alpha (p73 Delta exon2) inhibits apoptosis and competes with p53
ONCOGENE
Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells
ONCOGENE
Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation
ONCOGENE
New approaches to dissect degeneracy and specificity in T cell antigen recognition
JOURNAL OF MOLECULAR MEDICINE-JMM
Role of receptor activator of nuclear factor-kappa B ligand and osteoprotegerin in bone cell biology
JOURNAL OF MOLECULAR MEDICINE-JMM
Binding of human clusterin by Staphylococcus epidermidis
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
FILO (Field Interaction Ligand Optimization): A simplex strategy for searching the optimal ligand interaction field in drug design
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
SLATE: A method for the superposition of flexible ligands
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
Receptor mediated binding of avidin to polymer covered liposomes
JOURNAL OF LIPOSOME RESEARCH
In vivo blockade of the Fas-Fas ligand pathway inhibits cyclophosphamide-induced diabetes in NOD mice
JOURNAL OF AUTOIMMUNITY
p53 signaling and cell cycle checkpoints
CHEMICAL RESEARCH IN TOXICOLOGY
Molecular signals in anti-apoptotic survival pathways
LEUKEMIA
Tumor necrosis factor alpha-induced osteoclastogenesis requires tumor necrosis factor receptor-associated factor 6
JOURNAL OF BONE AND MINERAL RESEARCH
Expression profiles of receptor activator of nuclear factor kappa B ligand, receptor activator of nuclear factor kappa B, and osteoprotegerin messenger RNA in aged and ovariectomized rat bones
JOURNAL OF BONE AND MINERAL RESEARCH
Expression of osteoprotegerin, receptor activator of NF-kappa B ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracturehealing
JOURNAL OF BONE AND MINERAL RESEARCH
The ratio of messenger RNA levels of receptor activator of nuclear factor kappa B ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis
JOURNAL OF BONE AND MINERAL RESEARCH
T cell activation induces human osteoclast formation via receptor activator of nuclear factor kappa B ligand-dependent and -independent mechanisms
JOURNAL OF BONE AND MINERAL RESEARCH
Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions
JOURNAL OF BONE AND MINERAL RESEARCH
Osteosarcoma cell apoptosis induced by selenium
JOURNAL OF ORTHOPAEDIC RESEARCH
Utilization of a receptor reserve for effective amplification of mitogenicsignaling by an epidermal growth factor mutant deficient in receptor activation
JOURNAL OF CELLULAR BIOCHEMISTRY
Screening effect of PEG on avidin binding to liposome surface receptors
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Discriminative stimulus effects of panadiplon (U-78875), a partial agonistat the benzodiazepine site, in pentobarbital-trained rhesus monkeys
DRUG AND ALCOHOL DEPENDENCE
Antagonism of oestrogen action in human breast and endometrial cells in vitro: potential novel antitumour agents
CANCER CHEMOTHERAPY AND PHARMACOLOGY
Recognition force microscopy/spectroscopy of ion channels: applications tothe skeletal muscle Ca2+ release channel (RYR1)
ULTRAMICROSCOPY
Gene expression of glucocorticoid receptor alpha and beta in giant cell tumour of bone: evidence of glucocorticoid-stimulated osteoclastogenesis by stromal-like tumour cells
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Alterations in sperm protein phosphorylation in male infertility
ANDROLOGIA
Presence of osteoclast precursors in colonies cloned in the presence of hematopoietic colony-stimulating factors
EXPERIMENTAL HEMATOLOGY
Mechanisms of p53-dependent apoptosis
BIOCHEMICAL SOCIETY TRANSACTIONS
Osteoclastogenesis and osteoclast activation in dialysis-related amyloid osteopathy
AMERICAN JOURNAL OF KIDNEY DISEASES
Absolute quantification by positron emission tomography of the endogenous ligand
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Parametric images of the extrastriatal D2 receptor density obtained using a high-affinity ligand (FLB 457) and a double-saturation method
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Exogenous anandamide protects rat brain against acute neuronal injury in vivo
JOURNAL OF NEUROSCIENCE
Sevoflurane potentiates and blocks GABA-induced currents through recombinant alpha(1)ss(2)gamma(2) GABA(A) receptors: implications for an enhanced GABAergic transmission
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
Delivery of molecular and cellular medicine to solid tumors
ADVANCED DRUG DELIVERY REVIEWS
Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male componentof the self-incompatibility response
PLANT MOLECULAR BIOLOGY
A study on the density and distribution of uterine Natural Killer cells atmid pregnancy in mice genetically-ablated for CCR2, CCR 5 and the CCR5 receptor ligand, MIP-1 alpha
JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Water, treated as the continuous liquid in and around cells
CELLULAR AND MOLECULAR BIOLOGY
Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug- and Fas-induced apoptosis by a JNK independent pathway
LEUKEMIA RESEARCH
Selected concepts and investigations in compound classification, moleculardescriptor analysis, and virtual screening
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
Modeling of early events in T cell signal transduction after controlled T cell activation by peptide major histocompatibility complex
ANNALS OF BIOMEDICAL ENGINEERING
Controlled cell deformation produces defined areas of contact between cells and ligand-coated surfaces
ANNALS OF BIOMEDICAL ENGINEERING
A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease
KIDNEY INTERNATIONAL
Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides
VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 62
Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production
STROKE
Why do we need a three-dimensional architecture of the ligand-binding domain of the nuclear 1 alpha,25-dihydroxyvitamin D-3 receptor?
STEROIDS
Assessment of benzimidazole binding to individual recombinant tubulin isotypes from Haemonchus contortus
PARASITOLOGY
Effects of a novel, selective, sigma(1)-ligand, MS-377, on phencyclidine-induced behaviour
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
An endogenous cannabinoid (2-AG) is neuroprotective after brain injury
NATURE
Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The GDNF family: From neurotrophic factors to oncogenesis
MOLECULAR BIOLOGY
NMDA recepter-mediated neuroprotection by essential oils from the rhizomesof Acorus gramineus
LIFE SCIENCES
Mechanisms of endocannabinoid inactivation: Biochemistry and pharmacology
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Apoptotic events in a human ovarian cancer cell line exposed to anthracyclines
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Expression of tumour necrosis factor (TNF) ligand superfamily co-stimulatory molecules CD30L, CD27L, OX40L, and 4-I BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3
JOURNAL OF PATHOLOGY
Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration
JOURNAL OF NEUROCHEMISTRY
Expression of active protein kinase B in T cells perturbs both T and B cell homeostasis and promotes inflammation
JOURNAL OF IMMUNOLOGY
Immunosensitization of melanoma tumor cells to non-MHC Fas-mediated killing by MART-1-specific CTL cultures
JOURNAL OF IMMUNOLOGY
Localization of receptor activator of NF kappa B ligand, RANKL, in periodontal tissues during experimental movement of rat molars
JOURNAL OF ELECTRON MICROSCOPY
Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance
JOURNAL OF BIOLOGICAL CHEMISTRY
Neuroreceptor bindings and synaptic activity in visual system of monocularly enucleated rat
JAPANESE JOURNAL OF OPHTHALMOLOGY
Quantum chemical analysis of the interactions of transition state analogs with leucine aminopeptidase
INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
fMLP-induced respiratory burst and the intracellular Ca2+ signal are not interrelated in neutrophils
HAEMATOLOGIA
Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization
FEBS LETTERS
Ionizing radiation can overcome resistance to TRAIL in TRAIL-resistant cancer cells
FEBS LETTERS
Futile caspase-8 activation during the apoptotic cell death induced by DNAdamaging agents in human B-lymphoblasts
EXPERIMENTAL CELL RESEARCH
The neuropeptide FF analogue, 1DMe, acts as a functional opioid autoreceptor antagonist in the rat spinal cord
EUROPEAN JOURNAL OF PHARMACOLOGY
MS-377, a novel selective sigma(1) receptor ligand, reverses phencyclidine-induced release of dopamine and serotonin in rat brain
EUROPEAN JOURNAL OF PHARMACOLOGY
DNase I mediates internucleosomal DNA degradation in human cells undergoing drug-induced apoptosis
EUROPEAN JOURNAL OF IMMUNOLOGY
Metabolic characterization of sciadonic acid (5c,11c,14c-eicosatrienoic acid) as an effective substitute for arachidonate of phosphatidylinositol
EUROPEAN JOURNAL OF BIOCHEMISTRY
Early expression of pituitary adenylate cyclase-activating polypeptide andactivation of its receptor in chick neuroblasts
ENDOCRINOLOGY
Insulin binding monitored by fluorescence correlation spectroscopy
DIABETOLOGIA
Induction of apoptosis in 9-nitrocamptothecin-treated DU145 human prostatecarcinoma cells correlates with de novo synthesis of CD95 and CD95 ligand and down-regulation of c-FLIPshort
CANCER RESEARCH
The chemotherapeutic drug 5-fluorouracil induces apoptosis in mouse thymocytes in vivo via activation of the CD95(APO-1/Fas) system
CANCER RESEARCH
Receptor activator of nuclear factor-kappa B ligand and osteoprotegerin - Potential implications for the pathogenesis and treatment of malignant bonediseases
CANCER
Subcellular localization of thrombopoietin in human blood platelets and its release upon thrombin stimulation
BRITISH JOURNAL OF HAEMATOLOGY
Serum levels of soluble stem cell factor and soluble KIT are elevated in patients with atopic dermatitis and correlate with the disease severity
BRITISH JOURNAL OF DERMATOLOGY
Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediatekilling of B-chronic lymphocytic leukemia cells by cytotoxic drugs or gamma radiation
BLOOD
Signaling pathways activated by daunorubicin
BLOOD