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Nonisotopic methods for detecting activation of small G proteins
G PROTEIN PATHWAYS: PT C, EFFECTOR MECHANISMS
Antisense properties of 2 '-O-dimethylaminooxyethyl (2 '-O-DMAOE) oligonucleotides
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1 (vol 3, 550, 2001)
NEOPLASIA
Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1
NEOPLASIA
Rap1 signalling: Adhering to new models
NATURE REVIEWS MOLECULAR CELL BIOLOGY
GTP-dependent segregation of H-ras from lipid rafts is required for biological activity
NATURE CELL BIOLOGY
Phase I trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer
CLINICAL CANCER RESEARCH
Corticosterone supplementation reduced selective protein kinase C isoform expression in the epidermis of adrenalectomized mice
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
Discovery and analysis of antisense oligonucleotide activity in cell culture
METHODS
Control of oocyte recruitment: Regulative role of follicle cells through the release of a diffusible factor
MOLECULAR REPRODUCTION AND DEVELOPMENT
Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Upregulation of non-mutated H-ras and its upstream and downstream signaling proteins in colorectal cancer
ONCOLOGY REPORTS
Establishment and characterization of a murine mast cell line derived fromNC/Nga mice
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Ras effectors: Buying shares in Ras plc
CURRENT BIOLOGY
Regulating c-Ras function: cholesterol depletion affects caveolin association, GTP loading, and signaling
CURRENT BIOLOGY
Nod factor-induced phosphatidic acid and diacylglycerol pyrophosphate formation: a role for phospholipase C and D in root hair deformation
PLANT JOURNAL
Phase II trial with ISIS 5132 in patients with small-cell (SCLC) and non-small cell (NSCLC) lung cancer. A European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Studies Group Report
EUROPEAN JOURNAL OF CANCER
Increased sensitivity to cytosine arabinoside in human leukemia by c-raf-1antisense oligonucleotides
ANTI-CANCER DRUGS
Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria
ONCOGENE
P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells
ONCOGENE
Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions
ONCOGENE
Sustained activation of the Raf/MEK/Erk pathway in response to EGF in stable cell lines expressing the Hepatitis C Virus (HCV) core protein
ONCOGENE
Role of the EGFR/Ras/Raf pathway in specification of photoreceptor cells in the Drosophila retina
DEVELOPMENT
Encapsulation of c-myc antisense oligodeoxynucleotides in lipid particles improves antitumoral efficacy in vivo in a human melanoma line
CANCER GENE THERAPY
The cAMP-dependent protein kinase substrate Rap1 in platelets from patients with obsessive compulsive disorder or schizophrenia
EUROPEAN NEUROPSYCHOPHARMACOLOGY
UV-A-induced AP-1 activation requires the Raf/ERK pathway in human NCTC 2544 keratinocytes
EXPERIMENTAL DERMATOLOGY
Activation of Ras, Raf-1 and protein kinase C in differentiating human neuroblastoma cells after treatment with phorbolester and NGF
CELLULAR SIGNALLING
Mechanisms of inhibition of the Ras-MAP kinase signaling pathway in 30.7b Ras 12 cells by tea polyphenols (-)-epigallocatechin-3-gallate and theaflavin-3,3 '-digallate
FASEB JOURNAL
Analysis of the transcriptional program induced by Raf in epithelial cells
GENES & DEVELOPMENT
Activation of extracellular signal-regulated kinases and CREB/ATF-1 mediate the expression of CCAAT/enhancer binding proteins beta and -delta in preadipocytes
MOLECULAR ENDOCRINOLOGY
Unwinding the loop of Bcl-2 phosphorylation
LEUKEMIA
Phosphorylation of Bcl2 and regulation of apoptosis
LEUKEMIA
Additional copies of virG from pTiBo542 provide a super-transformation ability to Agrobacterium tumefaciens in citrus
PHYSIOLOGICAL AND MOLECULAR PLANT PATHOLOGY
Composition of the essential oil of Erechtites hieracifolia from Bolivia
FLAVOUR AND FRAGRANCE JOURNAL
Phosphorylation by PKA of a site unique to B-Raf kinase
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES
Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Pertussis toxin directly activates endothelial cell p42/p44 MAP kinases via a novel signaling pathway
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Molecular mechanisms of ATP and insulin synergistic stimulation of coronary artery smooth muscle growth
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Interactions between the PI3K and Raf signaling pathways can result in thetransformation of hematopoietic cells
CANCER DETECTION AND PREVENTION
Regulation of the p53 pathway by Ras, the plot thickens
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Ras and Rho regulation of the cell cycle and oncogenesis
CANCER LETTERS
The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D-3 in skeletal muscle cells is mediated by protein kinase C and calcium
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Retinoic acid causes MEK-dependent RAF phosphorylation through RAR alpha plus RXR activation in HL-60 cells
DIFFERENTIATION
Arsenic-induced NF kappa beta transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells
MOLECULAR AND CELLULAR BIOCHEMISTRY
Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1-and Rap1-B-Raf-dependent pathways
MOLECULAR AND CELLULAR BIOLOGY
S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3
MOLECULAR AND CELLULAR BIOLOGY
A Ras by any other name
MOLECULAR AND CELLULAR BIOLOGY
ZAP-70-independent Ca2+ mobilization and Erk activation in Jurkat T cells in response to T-Cell antigen receptor ligation
MOLECULAR AND CELLULAR BIOLOGY
Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt
MOLECULAR AND CELLULAR BIOLOGY
Cyclic AMP-mediated inhibition of cell growth requires the small G proteinRap1
MOLECULAR AND CELLULAR BIOLOGY
Stimulation of endothelin B receptors in astrocytes induces cAMP response element-binding protein phosphorylation and c-fos expression via multiple mitogen-activated protein kinase signaling pathways
JOURNAL OF NEUROSCIENCE
Nociceptor sensitization by extracellular signal-regulated kinases
JOURNAL OF NEUROSCIENCE
Design of inhibitors of Ras-Raf interaction using a computational combinatorial algorithm
PROTEIN ENGINEERING
Angiotensin subtype-2 receptor (AT(2)) negatively regulates subtype-1 receptor (AT(1)) in signal transduction pathways in cultured porcine adrenal medullary chromaffin cells
JOURNAL OF HYPERTENSION
MEK kinase activity is not necessary for Raf-1 function
EMBO JOURNAL
Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene
EMBO JOURNAL
Phospholipase C epsilon: a novel Ras effector
EMBO JOURNAL
Positive and negative regulation of Raf kinase activity and function by phosphorylation
EMBO JOURNAL
Role of MAP kinase pathways in primitive neuroectodermal tumors
ANTICANCER RESEARCH
Regulation of the Raf kinase by phosphorylation
EXPERIMENTAL LUNG RESEARCH
Nicotinic receptor-mediated activation by the tobacco-specific nitrosamineNNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmonary neuroendocrine cells
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Apoptosis inhibition mediated by medroxyprogesterone acetate treatment of breast cancer cell lines
BREAST CANCER RESEARCH AND TREATMENT
Parathyroid hormone activation of map kinase in rat duodenal cells is mediated by 3 ',5 '-cyclic AMP and Ca2+
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Ras activation of the Raf kinase: Tyrosine kinase recruitment of the MAP kinase cascade
RECENT PROGRESS IN HORMONE RESEARCH, VOL 56
Integrin regulation of receptor tyrosine kinase and G protein-coupled receptor signaling to mitogen-activated protein kinases
REGULATORS AND EFFECTORS OF SMALL GTPASES, PT G
RAS interaction with effector target RIN 1
REGULATORS AND EFFECTORS OF SMALL GTPASES, PT F, RAS FAMILY I
Scaffold protein regulation of mitogen-activated protein kinase cascade
REGULATORS AND EFFECTORS OF SMALL GTPASES, PT F, RAS FAMILY I
Steroid receptor fusion proteins for conditional activation of Raf-MEK-ERKsignaling pathway
REGULATORS AND EFFECTORS OF SMALL GTPASES, PT F, RAS FAMILY I
Comparative rates of density change in declining populations of the blackheaded budworm Acleris gloverana (Lepidoptera : Tortricidae) among differentsites on Vancouver Island
ENVIRONMENTAL ENTOMOLOGY
Radicicol and geldanamycin prevent neurotoxic effects of anti-cancer drugson cultured embryonic sensory neurons
NEUROPHARMACOLOGY
Spred is a Sprouty-related suppressor of Ras signalling
NATURE
Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Selective potentiation of paclitaxel (Taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines
MOLECULAR PHARMACOLOGY
Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway
MOLECULAR PHARMACOLOGY
Paclitaxel-induced immune suppression is associated with NF-kappa B activation via conventional PKC isotypes in lipopolysaccharide-stimulated 70Z/3 pre-B-lymphocyte tumor cells
MOLECULAR PHARMACOLOGY
A dynamical systems model to simulate the perturbation kinetics of gene expression by antisense oligonucleotides
JOURNAL OF THEORETICAL BIOLOGY
Extracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte cultures
JOURNAL OF NEUROCHEMISTRY
Domain shuffling as a tool for investigation of protein function: substitution of the cysteine-rich region of raf kinase and PKC eta for that of yeast Pkc1p
JOURNAL OF MOLECULAR BIOLOGY
Crystal structures of YBHB and YBCL from Escherichia coli, two bacterial homologues to a Raf kinase inhibitor protein
JOURNAL OF MOLECULAR BIOLOGY
Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Respiratory syncytial virus infection results in activation of multiple protein kinase C isoforms leading to activation of mitogen-activated protein kinase
JOURNAL OF IMMUNOLOGY
Surface glycoproteins bearing alpha-GalNAc terminated chains accompany pyriform cell differentiation in lizards
JOURNAL OF EXPERIMENTAL ZOOLOGY
Cell cycle roles for two 14-3-3 proteins during Drosophila development
JOURNAL OF CELL SCIENCE
Glial cell line-derived neurotrophic factor-stimulated phosphatidylinositol 3-kinase and Akt activities exert opposing effects on the ERK pathway - Importance for the rescue of neuroectodermic cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Neurotrophin receptor-interacting mage homologue is an inducible inhibitorof apoptosis protein-interacting protein that augments cell death
JOURNAL OF BIOLOGICAL CHEMISTRY
Cyclic AMP inhibits extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways by inhibiting Rap1
JOURNAL OF BIOLOGICAL CHEMISTRY
Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf
JOURNAL OF BIOLOGICAL CHEMISTRY
Sequential activation of protein kinase C (PKC)-alpha and PKC-epsilon contributes to sustained Raf/ERK1/2 activation in endothelial cells under mechanical strain
JOURNAL OF BIOLOGICAL CHEMISTRY
Constitutive association of c-N-Ras with c-Raf-1 and protein kinase C epsilon in latent signaling modules
JOURNAL OF BIOLOGICAL CHEMISTRY
Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin
JOURNAL OF BIOLOGICAL CHEMISTRY
Microtubule integrity regulates pak leading to ras-independent activation of Raf-1 - Insights into mechanisms of Raf-1 activation
JOURNAL OF BIOLOGICAL CHEMISTRY
A Ca1DAG-GEFI/Rap1/B-Raf cassette couples M-1 muscarinic acetylcholine receptors to the activation of ERK1/2
JOURNAL OF BIOLOGICAL CHEMISTRY
Effects of stimulation of AMP-activated protein kinase on insulinlike growth factor 1-and epidermal growth factor-dependent extracellular signal-regulated kinase pathway
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of the mechanisms regulating the differential activation ofthe MAPK cascade by epidermal growth factor and nerve growth factor in PC12 cells
JOURNAL OF BIOLOGICAL CHEMISTRY
cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons
JOURNAL OF BIOLOGICAL CHEMISTRY
Kinase suppressor of ras signals through Thr(269) of c-Raf-1
JOURNAL OF BIOLOGICAL CHEMISTRY
Regulation of adipogenesis by a transcriptional repressor that modulates MAPK activation
JOURNAL OF BIOLOGICAL CHEMISTRY
ERK5 and ERK2 cooperate to regulate NF-kappa B and cell transformation
JOURNAL OF BIOLOGICAL CHEMISTRY