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Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1,2-dithiole-3-thione
MOLECULAR MEDICINE
Expression of recombinant zeta-crystallin in Escherichia coli with the help of GroEL/ES and its purification
PROTEIN EXPRESSION AND PURIFICATION
Quinone oxidoreductase message levels are differentially regulated in parasitic and non-parasitic plants exposed to allelopathic quinones
PLANT JOURNAL
The antioxidant enzyme quinone reductase is up-regulated in vivo followingcerebral ischemia
NEUROREPORT
Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544
TOXICOLOGY IN VITRO
Antimutagenicity and induction of anticarcinogenic phase II enzymes by basidiomycetes
JOURNAL OF ETHNOPHARMACOLOGY
Mechanism of increased renal gene expression during metabolic acidosis
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons
DRUG METABOLISM REVIEWS
Enzymes in pancreatic islets that use NADP(H) as a cofactor including evidence for plasma membrane aldehyde reductase
MOLECULAR AND CELLULAR BIOCHEMISTRY
Induction of cytochrome P450 and/or detoxication enzymes by various extracts of rosemary: description of specific patterns
FOOD AND CHEMICAL TOXICOLOGY
Effects of a water-soluble extract of rosemary and its purified component rosmarinic acid on xenobiotic-metabolizing enzymes in rat liver
FOOD AND CHEMICAL TOXICOLOGY
The carboxin-binding site on Paracoccus denitrificans succinate : quinone reductase identified by mutations
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
Oxidation of reduced inorganic sulfur compounds by bacteria: Emergence of a common mechanism?
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
The synergistic upregulation of phase II detoxification enzymes by glucosinolate breakdown products in cruciferous vegetables
TOXICOLOGY AND APPLIED PHARMACOLOGY
Potency of Michael reaction accepters as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Sensitivity to carcinogenesis is increased and chemoprotective efficacy ofenzyme inducers is lost in nrf2 transcription factor-deficient mice
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: Involvement of both the glucocorticoid and pregnane X receptors
MOLECULAR PHARMACOLOGY
Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism
JOURNAL OF NUTRITION
Preferential expression of antioxidant response element mediated gene expression in astrocytes
JOURNAL OF NEUROCHEMISTRY
Regulation of human apolipoprotein A-I gene expression by equine estrogens
JOURNAL OF LIPID RESEARCH
Chemolithoheterotrophy in a metazoan tissue: thiosulfate production matches ATP demand in ciliated mussel gills
JOURNAL OF EXPERIMENTAL BIOLOGY
Putative ACP phosphodiesterase gene (acpD) encodes an azoreductase
JOURNAL OF BIOLOGICAL CHEMISTRY
Membrane-associated quinoprotein formaldehyde dehydrogenase from Methylococcus capsulatus Bath
JOURNAL OF BACTERIOLOGY
Novel genes of the sox gene cluster, mutagenesis of the flavoprotein SoxF,and evidence for a general sulfur-oxidizing system in Paracoccus pantotrophus GB17
JOURNAL OF BACTERIOLOGY
FMN is covalently attached to a threonine residue in the NqrB and NqrC subunits of Na+-translocating NADH-quinone reductase from Vibrio alginolyticus
FEBS LETTERS
Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2
BIOCHEMICAL PHARMACOLOGY
Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Recent progress in the Na+-translocating NADH-quinone reductase from the marine Vibrio alginolyticus
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Role of sodium bioenergetics in Vibrio cholerae
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Plasma membrane electron transport coupled to Na+ extrusion in the halotolerant alga Dunaliella
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
Estrogen receptor transcription and transactivation Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer
BREAST CANCER RESEARCH
Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
Molecular modelling of human DT-Diaphorase for enzyme-directed bioreductive drug design
MOLECULAR SIMULATION
L-Dopa stimulates expression of the antioxidant enzyme NAD(P)H : quinone oxidoreductase (NQO) in cultured astroglial cells
FREE RADICAL BIOLOGY AND MEDICINE
Persuasive evidence that quinone reductase type 1 (DT diaphorase) protectscells against the toxicity of electrophiles and reactive forms of oxygen
FREE RADICAL BIOLOGY AND MEDICINE
Structures of mammalian cytosolic quinone reductases
FREE RADICAL BIOLOGY AND MEDICINE
Immunodetection of NAD(P)H : quinone oxidoreductase 1 (NQO1) in human tissues
FREE RADICAL BIOLOGY AND MEDICINE
Regulation of genes encoding NAD(P)H : quinone oxidoreductases
FREE RADICAL BIOLOGY AND MEDICINE
Conjugation position of quercetin glucuronides and effect on biological activity
FREE RADICAL BIOLOGY AND MEDICINE
Mouse NRH : quinone oxidoreductase (NQO2): cloning of cDNA and gene- and tissue-specific expression
GENE
Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells
CANCER LETTERS
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin
BIOCHEMICAL SOCIETY TRANSACTIONS
Molecular and structural aspects of xenobiotic carbonyl metabolizing enzymes. Role of reductases and dehydrogenases in xenobiotic phase I reactions
TOXICOLOGY
NAD(P)H : quinone oxidoreductase activity is increased in hippocampal pyramidal neurons of patients with Alzheimer's disease
NEUROBIOLOGY OF AGING
Functional detection of chemopreventive glucosinolates in Arabidopsis thaliana
PLANT SCIENCE
Is estradiol a genotoxic mutagenic carcinogen?
ENDOCRINE REVIEWS
7-methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes
CARCINOGENESIS
Redox enzymes in the plant plasma membrane and their possible roles
PLANT CELL AND ENVIRONMENT
Antioxidant regulation of genes encoding enzymes that detoxify xenobioticsand carcinogens
CURRENT TOPICS IN CELLULAR REGULATION, VOL 36
Induction of quinone reductase and glutathione transferase in rat tissues by juglone and plumbagin
PLANTA MEDICA
Bioenergetics of marine bacteria - Respiration-coupled Na+ pump
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ATP production from the oxidation of sulfide in gill mitochondria of the ribbed mussel Geukensia demissa
JOURNAL OF EXPERIMENTAL BIOLOGY
Identification of the melatonin-binding site MT3 as the quinone reductase 2
JOURNAL OF BIOLOGICAL CHEMISTRY
A membrane-bound flavocytochrome c-sulfide dehydrogenase from the purple phototrophic sulfur bacterium Ectothiorhodospira vacuolata
JOURNAL OF BACTERIOLOGY
Covalently bound flavin in the NqrB and NqrC subunits of Na+-translocatingNADH-quinone reductase from Vibrio alginolyticus
FEBS LETTERS
Purification of the 45 kDa, membrane bound NADH dehydrogenase of Escherichia coli (NDH-2) and analysis of its interaction with ubiquinone analogues
FEBS LETTERS
Progress in understanding structure-function relationships in respiratory chain complex II
FEBS LETTERS
A novel NADPH : diamide oxidoreductase activity in Arabidopsis thaliana P1zeta-crystallin
EUROPEAN JOURNAL OF BIOCHEMISTRY
NRH : quinone oxidoreductase2 (NQO2)
CHEMICO-BIOLOGICAL INTERACTIONS
Chemoprevention of aflatoxin B-1 hepatocarcinogenesis by coumarin, a natural benzopyrone that ls a potent inducer of aflatoxin B-1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H : quinone oxidoreductase in rat liver
CANCER RESEARCH
Detection of the Na+-translocating NADH-quinone reductase in marine bacteria using a PCR technique
CANADIAN JOURNAL OF MICROBIOLOGY
Drug treatment of Parkinson's disease - Time for phase II
BIOCHEMICAL PHARMACOLOGY
Estrogen receptor beta mRNA in colon cancer cells: Growth effects of estrogen and genistein
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors invivo
JOURNAL OF THE NATIONAL CANCER INSTITUTE
The estrogen receptor family
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
DT-diaphorase-like quinone reductase in rat plasma
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Antioxidant roles of cellular ubiquinone and related redox cycles: Potentiated resistance of rat hepatocytes having stimulated NADPH-dependent ubiquinone reductase against hydrogen peroxide toxicity
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Inhibitor studies of a new antibiotic, korormicin, 2-n-heptyl-4-hydroxyquinoline N-oxide and Ag+ toward the Na+-translocating NADH-quinone reductase from the marine Vibrio alginolyticus
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Coordinate regulation of NAD(P)H : Quinone oxidoreductase and glutathione-S-transferases in primary cultures of rat neurons and glia: Role of the antioxidant/electrophile responsive element
GLIA
Glutathione redox potential in response to differentiation and enzyme inducers
FREE RADICAL BIOLOGY AND MEDICINE
The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions
MOLECULAR ENDOCRINOLOGY
Nrf1 and Nrf2 regulate ARE-mediated expression and coordinated induction of a battery of genes encoding proteins that protect cells against oxidativestress
MOLECULAR MEDICINE: NOVEL FINDINGS OF GENE DIAGNOSIS, REGULATION OF GENE EXPRESSION, AND GENE THERAPY
Estrogen receptor and the SERM concept
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
Effects of sulindac, sulindac metabolites, and aspirin on the activity of detoxification enzymes in HT-29 human colon adenocarcinoma cells
CANCER LETTERS
Evidence that ferric nitrilotriacetate mediates oxidative stress by down-regulating DT-diaphorase activity: implications for carcinogenesis
CANCER LETTERS
Structure and mechanism of cytosolic quinone reductases
BIOCHEMICAL SOCIETY TRANSACTIONS
Antioxidant functions of sulforaphane: a potent inducer of phase II detoxication enzymes
FOOD AND CHEMICAL TOXICOLOGY
The expression and regulation of drug metabolism in human placenta
ADVANCED DRUG DELIVERY REVIEWS
Effects of changes in membrane sodium flux on virulence gene expression inVibrio cholerae
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H : quinone oxidoreductase 1 (NQO1) to benzene toxicity
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Dietary compounds that induce cancer preventive phase 2 enzymes activate apoptosis at comparable doses in HT29 colon carcinoma cells
JOURNAL OF NUTRITION
NOS- and non-NOS NADPH diaphorases in the insular cortex of the Syrian golden hamster
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
Activation of transcription by estrogen receptor alpha and beta is cell type- and promoter-dependent
JOURNAL OF BIOLOGICAL CHEMISTRY
A fission yeast gene for mitochondrial sulfide oxidation
JOURNAL OF BIOLOGICAL CHEMISTRY
The polar flagellar motor of Vibrio cholerae is driven by an Na+ motive force
JOURNAL OF BACTERIOLOGY
Cloning and heterologous expression of NAD(P)H : quinone reductase of Arabidopsis thaliana, a functional homologue of animal DT-diaphorase
FEBS LETTERS
The role of chloroplastic NAD(P)H dehydrogenase in photoprotection
FEBS LETTERS
Leads for the development of neuroprotective treatment in Parkinson's disease and brain imaging methods for estimating treatment efficacy
EUROPEAN JOURNAL OF PHARMACOLOGY
Effect of butylated hydroxyanisole on the toxicity of 2-hydroxy-1,4-naphthoquinone to rats
CHEMICO-BIOLOGICAL INTERACTIONS
Cancer chemopreventive activity mediated by 4 '-bromoflavone, a potent inducer of phase II detoxification enzymes'
CANCER RESEARCH
Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase
BRITISH JOURNAL OF CANCER
DT-diaphorase activity in NSCLC and SCLC cell lines: a role for fos/jun regulation
BRITISH JOURNAL OF CANCER
Sequencing and preliminary characterization of the Na+-translocating NADH : ubiquinone oxidoreductase from Vibrio harveyi
BIOCHEMISTRY
Crystal structure of human quinone reductase type 2, a metalloflavoprotein
BIOCHEMISTRY
Protective effect of ethanol against acetaminophen-induced hepatotoxicity in mice - Role of NADH : quinone reductase
BIOCHEMICAL PHARMACOLOGY
COMPARISON OF DNA ADDUCT LEVELS ASSOCIATED WITH OXIDATIVE STRESS IN HUMAN PANCREAS
Mutation research. Fundamental and molecular mechanisms of mutagenesis
CANCER CHEMOPREVENTIVE AGENTS DISCOVERED BY ACTIVITY-GUIDED FRACTIONATION - A REVIEW
Current organic chemistry
Induction of a cytosolic 54 kDa protein in rat liver that is highly homologous to selenium-binding protein
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
Effects of lead on glutathione S-transferase expression in rat kidney: A dose-response study
TOXICOLOGICAL SCIENCES