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Prevalence and spectrum of rheumatic diseases associated with proteinase 3-antineutrophil cytoplasmic antibodies (ANCA) and myeloperoxidase-ANCA
RHEUMATOLOGY
Serine proteases increase oxidative stress in lung cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Inhibition of serine proteases by functionalized sulfonamides coupled to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold
BIOORGANIC & MEDICINAL CHEMISTRY
Gene polymorphisms of immunoregulatory cytokines and angiotensin-converting enzyme in Wegener's granulomatosis
JOURNAL OF MOLECULAR MEDICINE-JMM
Henoch-Schonlein purpura with IgG PR3-ANCA in a PiZZ alpha 1-antitrypsin deficient patient
NEPHROLOGY DIALYSIS TRANSPLANTATION
Analysis of anti-neutrophil cytoplasmic antibodies (ANCA): frequency and specificity in a sample of 191 homozygous (PiZZ) alpha1-antitrypsin-deficient subjects
NEPHROLOGY DIALYSIS TRANSPLANTATION
Antigenic specificity of anti-neutrophil cytoplasmic antibody
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
Anti-neutrophil cytoplasmic antibodies tests: Which tests should be used in practice?
INTERNAL MEDICINE
A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schonlein purpura
INTERNAL MEDICINE
Are antineutrophil cytoplasmic antibodies pathogenic? Experimental approaches to understand the antineutrophil cytoplasmic antibody phenomenon
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
Are antineutrophil cytoplasmic antibody-associated vasculitides pauci-immune?
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
Proteinase 3, Wegener's autoantigen: from gene to antigen
JOURNAL OF LEUKOCYTE BIOLOGY
More than destructive: neutrophil-derived serine proteases in cytokine bioactivity control
JOURNAL OF LEUKOCYTE BIOLOGY
An SV40 large T-antigen immortalized human umbilical vein endothelial cellline for anti-endothelial cell antibody detection
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Epitope mapping on Wegener's granulomatosis autoantigen proteinase 3
CHINESE MEDICAL JOURNAL
Cellular aspects of vasculitis - T cell-mediated aspects
SPRINGER SEMINARS IN IMMUNOPATHOLOGY
Comparison of anti-PR3 capture and anti-PR3 direct ELISA for detection of antineutrophil cytoplasmic antibodies (ANCA) in long-term clinical follow-up of PR3-ANCA-associated vasculitis patients
CLINICAL NEPHROLOGY
Colocalization of ANCA-antigens and fibrinoid necrosis in ANCA-associated vasculitis
KIDNEY INTERNATIONAL
ANCA signaling: Not just a matter of respiratory burst
KIDNEY INTERNATIONAL
Anti-neutrophil cytoplasmic antibodies (ANCA) from patients with systemic vasculitis recognize restricted epitopes of proteinase 3 involving the catalytic site
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Antineutrophil cytoplasmic antibodies induce human monocytes to produce oxygen radicals in vitro
ARTHRITIS AND RHEUMATISM
1,2,5-Thiadiazolidin-3-one 1,1 dioxide: A powerful scaffold for probing the S ' subsites of (chymo)trypsin-like serine proteases
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Clinical and immunological aspects of Wegener's Granulomatosis (WG) and other syndromes resembling WG
ISRAEL MEDICAL ASSOCIATION JOURNAL
On the origin of surface proteinase 3 of nonmyeloid cells: Evidence favoring an exogenous source
CLINICAL IMMUNOLOGY
What you should know about PR3-ANCA - An introduction
ARTHRITIS RESEARCH
What you should know about PR3-ANCA - Structural aspects of antibodies to proteinase 3 (PR3)
ARTHRITIS RESEARCH
What you should know about PR3-ANCA - Evidence for the role of T cells in the pathogenesis of systemic vasculitis
ARTHRITIS RESEARCH
What you should know about PR3-ANCA - Conformational requirements of proteinase 3 (PR3) for enzymatic activity and recognition by PR3-ANCA
ARTHRITIS RESEARCH
Activation of progelatinase B by membranes of human polymorphonuclear granulocytes
BIOLOGICAL CHEMISTRY
Activation of neutrophils, eosinophils, and lymphocytes in the lower respiratory tract in Wegener's granulomatosis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Upregulation of CD14 and CD18 on monocytes in vitro by antineutrophil cytoplasmic autoantibodies
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Proteinase 3 interacts with a 111-kD membrane molecule of human umbilical vein endothelial cells
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Potent inhibition of serine proteases by heterocyclic sulfide derivatives of 1,2,5-thiadiazolidin-3-one 1,1 dioxide
BIOORGANIC & MEDICINAL CHEMISTRY
6-Acylamino-2-[(alkylsulfonyl)oxy]-1H-isoindole-1,3-dione mechanism-based inhibitors of human leukocyte elastase
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Vasculitic Wallenberg syndrome with detection of anti-proteinase 3 antibodies in the cerebrospinal fluid of a patient with severe Wegener's granulomatosis and only mild kidney involvement
NEPHROLOGY DIALYSIS TRANSPLANTATION
Neutrophil polynuclear anticytoplasm antibodies in systemic vaculitides
REVUE DES MALADIES RESPIRATOIRES
How and why should we detect ANCA?
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
De novo synthesis of proteinase 3 by cytokine primed circulating human polymorphonuclear neutrophils and mononuclear cells
JOURNAL OF RHEUMATOLOGY
Cigarette smoking and pauci-immune extracapillary glomerulonephritis with ANCA-associated idiopathic systemic vasculitis - A retrospective study
CIGARETTE SMOKING AND THE KIDNEY
T cell activation in patients with ANCA-associated vasculitis: inefficientimmune suppression by therapy
CLINICAL NEPHROLOGY
Epitope analysis of myeloperoxidase(MPO) specific anti-neutrophil cytoplasmic autoantibodies (ANCA) in MPO-ANCA-associated glomerulonephritis
CLINICAL NEPHROLOGY
Pulmonary giant bulla in Wegener's granulomatosis
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
Simultaneous presence of C-ANCA and P-ANCA in a patient with concurrent Churg-Strauss syndrome and giant cell temporal arteritis
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY
Identification and structural analysis of four serine proteases in a monotreme, the platypus, Ornithorhynchus anatinus
IMMUNOGENETICS
Antiproteinase 3-and antimyeloperoxidase-associated vasculitis
KIDNEY INTERNATIONAL
Antineutrophil cytoplasmic antibodies (ANCA) and systemic vasculitis: Update of assays, immunopathogenesis, controversies, and report of a novel de novo ANCA-associated vasculitis after kidney transplantation
SEMINARS IN ARTHRITIS AND RHEUMATISM
ANCA-associated vasculitis - an autopsy study
WIENER KLINISCHE WOCHENSCHRIFT
Heterogeneity of anti-PR3 associated disease in Hong Kong
POSTGRADUATE MEDICAL JOURNAL
Mutagenesis of the signal sequence of yellow fever virus prM protein: Enhancement of signalase cleavage in vitro is lethal for virus production
JOURNAL OF VIROLOGY
Recombinant proteinase 3 produced in different expression systems: recognition by anti-PR3 antibodies
JOURNAL OF IMMUNOLOGICAL METHODS
Effect of DNase on the activity of neutrophil elastase, cathepsin G and proteinase 3 in the presence of DNA
FEBS LETTERS
In vitro T lymphocyte responses to proteinase 3 (PR3) and linear peptides of PR3 in patients with Wegener's granulomatosis (WG)
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Granulocyte-macrophage colony-stimulating factor (GM-CSF) but not granulocyte colony-stimulating factor (G-CSF) induces plasma membrane expression ofproteinase 3 (PR3) on neutrophils in vitro
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Staphylococcal acid phosphatase binds to endothelial cells via charge interaction; a pathogenic role in Wegener's granulomatosis?
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Induction of neutrophil responsiveness to myeloperoxidase antibodies by their exposure to supernatant of degranulated autologous neutrophils
BLOOD
Prediction of relapses in Wegener's granulomatosis by measurement of antineutrophil cytoplasmic antibody levels - A prospective study
ARTHRITIS AND RHEUMATISM
Donor-recipient polymorphism of the proteinase 3 gene: A potential target for T-cell alloresponses to myeloid leukemia
JOURNAL OF IMMUNOTHERAPY
Rapidly progressive glomerulonephritis
JOURNAL OF NEPHROLOGY
The prevalence and clinical significance of alpha(1)-antitrypsin deficiency (PiZ) and ANCA specificities (Proteinase 3, BPI) in patients with ulcerative colitis
INFLAMMATORY BOWEL DISEASES
Immunopathology of ANCA-associated vasculitis
INTERNAL MEDICINE
In vitro up-regulation of E-selectin and induction of interleukin-6 in endothelial cells by autoantibodies in Wegener's granulomatosis and microscopic polyangiitis
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Irregular cytokine pattern of CD4(+) T lymphocytes in response to Staphylococcus aureus in patients with Wegener's granulomatosis
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
Treatment of acute c-ANCA-positive vasculitis with mycophenolate mofetil
AMERICAN JOURNAL OF KIDNEY DISEASES
Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (Caspase-1)
JOURNAL OF CLINICAL IMMUNOLOGY
Regulation of production of soluble Fc gamma receptors type III in normal and pathological conditions
IMMUNOLOGY LETTERS
Expression of major histocompatibility class II antigens on polymorphonuclear neutrophils in patients with Wegener's granulomatosis
KIDNEY INTERNATIONAL
The inhibition of myeloperoxidase by ceruloplasmin can be reversed by anti-myeloperoxidase antibodies
KIDNEY INTERNATIONAL
ANCA: Fuel for the fire or the spark that ignites the flame?
KIDNEY INTERNATIONAL
Wegener's granulomatosis
THORAX
A comparison of commercial and in-house ELISAs for antineutrophil cytoplasmic antibodies directed against proteinase 3 and myeloperoxidase
PATHOLOGY
Evidence for a crucial role of neutrophil-derived serine proteases in the inactivation of interleukin-6 at sites of inflammation
FEBS LETTERS
Proteinase 3 mRNA expression is induced in monocytes but not in neutrophils of patients with cystic fibrosis
FEBS LETTERS
Anti-PR-3 antibodies induce endothelial IL-8 release
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
Interaction of purified human proteinase 3 (PR3) with reconstituted lipid bilayers
EUROPEAN JOURNAL OF BIOCHEMISTRY
Characterization of monoclonal antibodies to proteinase 3 (PR3) as candidate tools for epitope mapping of human anti-PR3 autoantibodies
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
C3 and C4 allotypes in anti-neutrophil cytoplasmic autoantibody (ANCA)-positive vasculitis
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Anti-proteinase-3 (PR3) antibodies (C-ANCA) recognize various targets on the human umbilical vein endothelial cell (HUVEC) membrane
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia
CANCER RESEARCH
Changes in chromatin organization at the neutrophil elastase locus associated with myeloid cell differentiation
BLOOD
Biochemical characterization of alpha-ketooxadiazoie inhibitors of elastases
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Identification and characterization of Spodoptera frugiperda furin: A thermostable subtilisin-like endoprotease
BIOLOGICAL CHEMISTRY
FUNCTIONAL-PROPERTIES OF ANTIENDOTHELIAL CELL ANTIBODIES
Clinical reviews in allergy and immunology
PRODUCTION OF RECOMBINANT HUMAN MONOCYTE NEUTROPHIL ELASTASE INHIBITOR (RM NEI)/
Protein expression and purification (Print)
POTENT AND SPECIFIC-INHIBITION OF HUMAN-LEUKOCYTE ELASTASE, CATHEPSIN-G AND PROTEINASE-3 BY SULFONE DERIVATIVES EMPLOYING THE 1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE SCAFFOLD
Bioorganic & medicinal chemistry
PATHOGENESIS OF VASCULITIS
Lupus
DISEASE SPECTRUM OF PATIENTS WITH ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES OF DEFINED SPECIFICITY - DISTINCT DIFFERENCES BETWEEN PATIENTS WITH ANTIPROTEINASE 3 AND ANTIMYELOPEROXIDASE AUTOANTIBODIES
Journal of internal medicine
AUTOANTIBODIES TO MYELOPEROXIDASE - CLINICAL AND PATHOPHYSIOLOGICAL SIGNIFICANCE
Journal of molecular medicine
CYCLOSPORINE FOR THE PREVENTION OF DISEASE REACTIVATION IN RELAPSING ANCA-ASSOCIATED VASCULITIS
Nephrology, dialysis, transplantation
COINCIDENCE OF HEMOLYTIC-UREMIC SYNDROME AND C-ANCA-ASSOCIATED RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS
Nephrology, dialysis, transplantation
PATHOGENESIS OF THE VASCULAR AND GLOMERULAR DAMAGE IN ANCA-POSITIVE VASCULITIS
Nephrology, dialysis, transplantation
ANTI-PHAGOCYTE ANTIBODIES AND INFECTION
Autoimmunity (Print)
ANTINEUTROPHIL CYTOPLASM AUTOANTIBODIES (ANCA) - THE NEED FOR SPECIFIC AND SENSITIVE ASSAYS
Autoimmunity
ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN CHILDHOOD SYSTEMIC LUPUS-ERYTHEMATOSUS
Clinical rheumatology
STRUCTURE AND SEQUENCE OF HUMAN M NEI (MONOCYTE/NEUTROPHIL ELASTASE INHIBITOR), AN OV-SERPIN FAMILY GENE/
Gene
Clinical immunology - are there new results? ANCA-associated vasculitis: new aspects of nomenclature, epidemiology and etiopathogenesis
ALLERGOLOGIE
THE PRESENCE OF CYTOPLASMIC ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES (C-ANCA) IN THE COURSE OF SUBACUTE BACTERIAL-ENDOCARDITIS WITH GLOMERULARINVOLVEMENT, COINCIDENCE OR ASSOCIATION
Clinical nephrology
STUDY OF ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN PATIENTS WITH THROMBOANGIITIS-OBLITERANS (BUERGERS-DISEASE)
Scandinavian journal of immunology
Antineutrophil cytoplasmic antibodies as markers for systemic autoimmune disease
CLINICS IN CHEST MEDICINE
DETERMINATION OF PRIMARY AMINO-ACID-SEQUENCE AND UNIQUE 3-DIMENSIONALSTRUCTURE OF WGH1, A MONOCLONAL HUMAN-IGM ANTIBODY WITH ANTI-PR3 SPECIFICITY
Clinical immunology and immunopathology (Print)
DIAGNOSTIC-VALUE OF STANDARDIZED ASSAYS FOR ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN IDIOPATHIC SYSTEMIC VASCULITIS
Kidney international