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La ricerca find articoli where soggetti phrase all words 'PROTEIN ENGINEERING' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 588 riferimenti
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    1. Rotticci, D; Rotticci-Mulder, JC; Denman, S; Norin, T; Hult, K
      Improved enantioselectivity of a lipase by rational protein engineering

      CHEMBIOCHEM
    2. Yan, LZ; Dawson, PE
      Design and synthesis of a protein catenane

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    3. Chatani, E; Hayashi, R
      Functional and structural roles of constituent amino acid residues of bovine pancreatic ribonuclease A

      JOURNAL OF BIOSCIENCE AND BIOENGINEERING
    4. Murooka, Y; Yamashita, M
      Genetic and protein engineering of diagnostic enzymes, cholesterol oxidaseand xylitol oxidase

      JOURNAL OF BIOSCIENCE AND BIOENGINEERING
    5. Sidhu, SS
      Engineering M13 for phage display

      BIOMOLECULAR ENGINEERING
    6. van den Heuvel, RHH; Fraaije, MW; Mattevi, A; Laane, C; van Berkel, WJH
      Vanillyl-alcohol oxidase, a tasteful biocatalyst

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    7. Williams, LE; Wu, AM; Yazaki, PJ; Liu, A; Raubitschek, AA; Shively, JE; Wong, JYC
      Numerical selection of optimal tumor imaging agents with application to engineered antibodies

      CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
    8. Schwarzer, D; Mootz, HD; Marahiel, MA
      Exploring the impact of different thioesterase domains for the design of hybrid peptide synthetases

      CHEMISTRY & BIOLOGY
    9. Liang, TB; Tan, KH; Chong, K; Zhu, ZQ; Pongor, S; Simoncsits, A
      Selection and design of high affinity DNA ligands for mutant single-chain derivatives of the bacteriophage 434 repressor

      SCIENCE IN CHINA SERIES C-LIFE SCIENCES
    10. Budisa, N; Alefelder, S; Bae, JH; Golbik, R; Minks, C; Huber, R; Moroder, L
      Proteins with beta-(thienopyrrolyl)alanines as alternative chromophores and pharmaceutically active amino acids

      PROTEIN SCIENCE
    11. Torrent, J; Rubens, P; Ribo, M; Heremans, K; Vilanova, M
      Pressure versus temperature unfolding of ribonuclease A: An FTIR spectroscopic characterization of 10 variants at the carboxy-terminal site

      PROTEIN SCIENCE
    12. Ni, XH; Schachman, HK
      In vivo assembly of aspartate transcarbamoylase from fragmented and circularly permuted catalytic polypeptide chains

      PROTEIN SCIENCE
    13. Beernink, PT; Yang, YR; Graf, R; King, DS; Shah, SS; Schachman, HK
      Random circular permutation leading to chain disruption within and near alpha helices in the catalytic chains of aspartate transcarbamoylase: Effectson assembly, stability, and function

      PROTEIN SCIENCE
    14. Luong, TN; Kirsch, JF
      A general method for the quantitative analysis of functional chimeras: Applications from site-directed mutagenesis and macromolecular association

      PROTEIN SCIENCE
    15. Brych, SR; Blaber, SI; Logan, TM; Blaber, M
      Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil

      PROTEIN SCIENCE
    16. Vogt, M; Skerra, A
      Bacterially produced apolipoprotein D binds progesterone and arachidonic acid, but not bilirubin or E-3M2H

      JOURNAL OF MOLECULAR RECOGNITION
    17. Inanaga, H; Kobayasi, D; Kouzuma, Y; Aoki-Yasunaga, C; Iiyama, K; Kimura, M
      Protein engineering of novel proteinase inhibitors and their effects on the growth of Spodoptera exigua larvae

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    18. Methot, D; vanKats, JP; Lochard, N; Tremblay, F; Silversides, DW; Reudelhuber, TL
      Development and application of a biological peptide pump for the study of the in vivo actions of angiotensin peptides

      AMERICAN JOURNAL OF HYPERTENSION
    19. Selzer, T; Schreiber, G
      New insights into the mechanism of protein-protein association

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    20. Reddy, BVB; Li, WW; Shindyalov, IN; Bourne, PE
      Conserved key amino acid positions (CKAAPs) derived from the analysis of common substructures in proteins

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    21. Parrish, JC; Guillemette, JG; Wallace, CJA
      Contribution of leucine 85 to the structure and function of Saccharomyces cerevisiae iso-1 cytochrome c

      BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
    22. Damborsky, J; Rorije, E; Jesenska, A; Nagata, Y; Klopman, G; Peijnenburg, WJGM
      Structure-specificity relationships for haloalkane dehalogenases

      ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
    23. Fiedler, M; Skerra, A
      proBA complementation of an auxotrophic E-coli strain improves plasmid stability and expression yield during fermenter production of a recombinant antibody fragment

      GENE
    24. Daff, S; Noble, MA; Craig, DH; Rivers, SL; Chapman, SK; Munro, AW; Fujiwara, S; Rozhkova, E; Sagami, I; Shimizu, T
      Control of electron transfer in neuronal NO synthase

      BIOCHEMICAL SOCIETY TRANSACTIONS
    25. Kim, GJ; Cheon, YH; Park, MS; Park, HS; Kim, HS
      Generation of protein lineages with new sequence spaces by functional salvage screen

      PROTEIN ENGINEERING
    26. Gesell, JJ; Liu, DJ; Madison, VS; Hesson, T; Wang, YS; Weber, PC; Wyss, DF
      Design, high-level expression, purification and characterization of soluble fragments of the hepatitis C virus NS3 RNA helicase suitable for NMR-based drug discovery methods and mechanistic studies

      PROTEIN ENGINEERING
    27. Liang, TB; Chen, JQ; Tjornhammar, ML; Pongor, S; Simoncsits, A
      Modular construction of extended DNA recognition surfaces: mutant DNA-binding domains of the 434 repressor as building blocks

      PROTEIN ENGINEERING
    28. Jonson, PH; Petersen, SB
      A critical view on conservative mutations

      PROTEIN ENGINEERING
    29. Pedone, E; Saviano, M; Rossi, M; Bartolucci, S
      A single point mutation (Glu85Arg) increases the stability of the thioredoxin from Escherichia coli

      PROTEIN ENGINEERING
    30. Turner, NA; Gaskin, DJH; Yagnik, AT; Littlechild, JA; Vulfson, EN
      Enantioselectivity of recombinant Rhizomucor miehei lipase in the ring opening of oxazolin-5(4H)-ones

      PROTEIN ENGINEERING
    31. Gianese, G; Argos, P; Pascarella, S
      Structural adaptation of enzymes to low temperatures

      PROTEIN ENGINEERING
    32. Narhi, LO; Arakawa, T; Aoki, K; Wen, J; Elliott, S; Boone, T; Cheetham, J
      Asn to Lys mutations at three sites which are N-glycosylated in the mammalian protein decrease the aggregation of Escherichia coli-derived erythropoietin

      PROTEIN ENGINEERING
    33. Black, KM; Clark-Lewis, I; Wallace, CJA
      Conserved tryptophan in cytochrome c: importance of the unique side-chain features of the indole moiety

      BIOCHEMICAL JOURNAL
    34. Ren, XJ; Gao, SJ; You, DL; Huang, HL; Liu, Z; Mu, Y; Liu, JQ; Zhang, Y; Yan, GL; Luo, GM; Yang, TS; Shen, JC
      Cloning and expression of a single-chain catalytic antibody that acts as aglutathione peroxidase mimic with high catalytic efficiency

      BIOCHEMICAL JOURNAL
    35. Labrou, NE; Mello, LV; Clonis, YD
      Functional and structural roles of the glutathione-binding residues in maize (Zea mays) glutathione S-transferase I

      BIOCHEMICAL JOURNAL
    36. Di Gaetano, S; D'Alessio, G; Piccoli, R
      Second generation antitumour human RNase: significance of its structural and functional features for the mechanism of antitumour action

      BIOCHEMICAL JOURNAL
    37. Labrou, NE; Rigden, DJ
      Active-site characterization of Candida boidinii formate dehydrogenase

      BIOCHEMICAL JOURNAL
    38. Lietha, D; Chirgadze, DY; Mulloy, B; Blundell, TL; Gherardi, E
      Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor

      EMBO JOURNAL
    39. Kliche, W; Fujita-Becker, S; Kollmar, M; Manstein, DJ; Kull, FJ
      Structure of a genetically engineered molecular motor

      EMBO JOURNAL
    40. Carter, PH; Gardella, TJ
      Zinc(II)-mediated enhancement of the agonist activity of histidine-substituted parathyroid hormone(1-14) analogues

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
    41. Wintrode, PL; Miyazaki, K; Arnold, FH
      Patterns of adaptation in a laboratory evolved thermophilic enzyme

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    42. Scarafoni, A; Carzaniga, R; Harris, N; Croy, RRD
      Manipulation of the napin primary structure alters its packaging and deposition in transgenic tobacco (Nicotiana tabacum L.) seeds

      PLANT MOLECULAR BIOLOGY
    43. Cazorla, D; Ferrer-Miralles, N; Feliu, JX; Carbonell, X; Villaverde, A
      Plasmid maintenance and recombinant cell fitness explored in bacterial colonies

      BIOTECHNOLOGY LETTERS
    44. Chakrabarti, P; Pal, D
      The interrelationships of side-chain and main-chain conformations in proteins

      PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
    45. Hiipakka, M; Huotari, P; Manninen, A; Renkema, GH; Saksela, K
      Inhibition of cellular functions of HIV-1 Nef by artificial SH3 domains

      VIROLOGY
    46. Craik, DJ
      Plant cyclotides: circular, knotted peptide toxins

      TOXICON
    47. Wurth, C; Thomas, RM; Folkers, G; Scapozza, L
      Folding and self-assembly of herpes simplex virus type 1 thymidine kinase

      JOURNAL OF MOLECULAR BIOLOGY
    48. Arndt, KM; Muller, KM; Pluckthun, A
      Helix-stabilized Fv (hsFv) antibody fragments: Substituting the constant domains of a Fab fragment for a heterodimeric coiled-coil domain

      JOURNAL OF MOLECULAR BIOLOGY
    49. Honegger, A; Pluckthun, A
      Yet another numbering scheme for immunoglobulin variable domains: An automatic modeling and analysis tool

      JOURNAL OF MOLECULAR BIOLOGY
    50. Honegger, A; Pluckthun, A
      The influence of the buried glutamine or glutamate residue in position 6 on the structure of immunoglobulin variable domains

      JOURNAL OF MOLECULAR BIOLOGY
    51. Frank, S; Kammerer, RA; Mechling, D; Schulthess, T; Landwehr, R; Bann, J; Guo, Y; Lustig, A; Bachinger, HP; Engel, J
      Stabilization of short collagen-like triple helices by protein engineering

      JOURNAL OF MOLECULAR BIOLOGY
    52. Frisch, C; Fersht, AR; Schreiber, G
      Experimental assignment of the structure of the transition state for the association of barnase and barstar

      JOURNAL OF MOLECULAR BIOLOGY
    53. Sam, MD; Horton, NC; Nissan, TA; Perona, JJ
      Catalytic efficiency and sequence selectivity of a restriction endonuclease modulated by a distal manganese ion binding site

      JOURNAL OF MOLECULAR BIOLOGY
    54. Archontis, G; Simonson, T; Karplus, M
      Binding free energies and free energy components from molecular dynamics and Poisson-Boltzmann calculations. Application to amino acid recognition byaspartyl-tRNA synthetase

      JOURNAL OF MOLECULAR BIOLOGY
    55. Griffin, MD; Holman, PO; Tang, QZ; Ashourian, N; Korthauer, U; Kranz, DM; Bluestone, JA
      Development and applications of surface-linked single chain antibodies against T-cell antigens

      JOURNAL OF IMMUNOLOGICAL METHODS
    56. Takahashi, M; Hasuura, Y; Nakamori, S; Takagi, H
      Improved autoprocessing efficiency of mutant subtilisins E with altered specificity by engineering of the pro-region

      JOURNAL OF BIOCHEMISTRY
    57. Shimotohno, A; Oue, S; Yano, T; Kuramitsu, S; Kagamiyama, R
      Demonstration of the importance and usefulness of manipulating non-active-site residues in protein design

      JOURNAL OF BIOCHEMISTRY
    58. Roesler, KR; Rao, AG
      Rapid gastric fluid digestion and biochemical characterization of engineered proteins enriched in essential amino acids

      JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
    59. Tabuchi, I; Soramoto, S; Nemoto, N; Husimi, Y
      An in vitro DNA virus for in vitro protein evolution

      FEBS LETTERS
    60. Nelson, SW; Honzatko, RB; Fromm, HJ
      Spontaneous subunit exchange in porcine liver fructose-1,6-bisphosphatase

      FEBS LETTERS
    61. Jones, JP; O'Hare, EJ; Wong, LL
      Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cytochrome P450(cam))

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    62. Labrou, NE; Mello, LV; Clonis, YD
      The conserved Asn49 of maize glutathione S-transferase I modulates substrate binding, catalysis and intersubunit communication

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    63. Carmichael, AB; Wong, LL
      Protein engineering of Bacillus megaterium CYP102 - The oxidation of polycyclic aromatic hydrocarbons

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    64. Viti, F; Pedrioli, P; Mitta, B; Neri, D
      Phage display libraries as a source of tumour-targeting agents

      CHIMIA
    65. Penning, TM; Ma, HC; Jez, JM
      Engineering steroid hormone specificity into aldo-keto reductases

      CHEMICO-BIOLOGICAL INTERACTIONS
    66. Barriault, D; Simard, C; Chatel, H; Sylvestre, M
      Characterization of hybrid biphenyl dioxygenases obtained by recombining Burkholderia sp strain LB400 bphA with the homologous gene of Comamonas testosteroni B-356

      CANADIAN JOURNAL OF MICROBIOLOGY
    67. Hansson, T; Kaper, T; van der Oost, J; de Vos, WM; Adlercreutz, P
      Improved oligosaccharide synthesis by protein engineering of beta-glucosidase CelB from hyperthermophilic Pyrococcus furiosus

      BIOTECHNOLOGY AND BIOENGINEERING
    68. Pan, YP; Daggett, V
      Direct comparison of experimental and calculated folding free energies forhydrophobic deletion mutants of chymotrypsin inhibitor 2: Free energy perturbation calculations using transition and denatured states from molecular dynamics simulations of unfolding

      BIOCHEMISTRY
    69. Kong, XD; Liu, YM; Gou, XJ; Zhu, SH; Zhang, HY; Wang, XP; Zhang, J
      Directed evolution of alpha-aspartyl dipeptidase from Salmonella typhimurium

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    70. Takeda, S; Kamiya, N; Arai, R; Nagamune, T
      Design of an artificial light-harvesting unit by protein engineering: Cytochrome b(562)-green fluorescent protein chimera

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    71. Volpicella, M; Ceci, LR; Gallerani, R; Jongsma, MA; Beekwilder, J
      Functional expression on bacteriophage of the mustard trypsin inhibitor MTI-2

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    72. Clerico, EM; Ermacora, MR
      Tryptophan mutants of intestinal fatty acid-binding protein: Ultraviolet absorption and circular dichroism studies

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    73. Karlstrom, A; Nygren, PA
      Dual labeling of a binding protein allows for specific fluorescence detection of native protein

      ANALYTICAL BIOCHEMISTRY
    74. McGregor, DP; Robins, SP
      External surface display of proteins linked to DNA-binding domains

      ANALYTICAL BIOCHEMISTRY
    75. Nishiya, Y; Yamamoto, K; Kawamura, Y; Emi, S
      Development of creatinine-degrading enzymes for application to clinical assays

      NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY
    76. Lynch, TJ
      Biotechnology: alternatives to human plasma-derived therapeutic proteins

      BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
    77. Nixon, AE; Firestine, SM
      Rational and "irrational" design of proteins and their use in biotechnology

      IUBMB LIFE
    78. Pilone, MS
      D-Amino acid oxidase: new findings

      CELLULAR AND MOLECULAR LIFE SCIENCES
    79. Pleiss, J; Fischer, M; Peiker, M; Thiele, C; Schmid, RD
      Lipase engineering database - Understanding and exploiting sequence-structure-function relationships

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    80. Richter, LJ; Thanavala, Y; Arntzen, CJ; Mason, HS
      Production of hepatitis B surface antigen in transgenic plants for oral immunization

      NATURE BIOTECHNOLOGY
    81. Movileanu, L; Howorka, S; Braha, O; Bayley, H
      Detecting protein analytes that modulate transmembrane movement of a polymer chain within a single protein pore

      NATURE BIOTECHNOLOGY
    82. Cotton, GJ; Muir, TW
      Generation of a dual-labeled fluorescence biosensor for Crk-II phosphorylation using solid-phase expressed protein ligation

      CHEMISTRY & BIOLOGY
    83. Elliott, RJ; Bennet, AJ; Braun, CA; MacLeod, AM; Borgford, TJ
      Active-site variants of Streptomyces griseus protease B with peptide-ligation activity

      CHEMISTRY & BIOLOGY
    84. Bishop, A; Buzko, O; Heyeck-Dumas, S; Jung, I; Kraybill, B; Liu, Y; Shah, K; Ulrich, S; Witucki, L; Yang, F; Zhang, C; Shokat, KM
      Unnatural ligands for engineered proteins: New tools for chemical genetics

      ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE
    85. Morea, V; Lesk, AM; Tramontano, A
      Antibody modeling: Implications for engineering and design

      METHODS-A COMPANION TO METHODS IN ENZYMOLOGY
    86. Liang, SD; Xiao, L; Mao, FL; Jiang, L; Han, YZ; Lai, LH
      Grafting of protein-protein binding sites

      CHINESE SCIENCE BULLETIN
    87. Thoma, R; Hennig, M; Sterner, R; Kirschner, K
      Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima

      STRUCTURE WITH FOLDING & DESIGN
    88. Schymkowitz, JWH; Rousseau, F; Irvine, LR; Itzhaki, LS
      The folding pathway of the cell-cycle regulatory protein p13suc1: clues for the mechanism of domain swapping

      STRUCTURE WITH FOLDING & DESIGN
    89. Roesler, KR; Rao, AG
      A single disulfide bond restores thermodynamic and proteolytic stability to an extensively mutated protein

      PROTEIN SCIENCE
    90. Villegas, V; Zurdo, J; Filimonov, VV; Aviles, FX; Dobson, CM; Serrano, L
      Protein engineering as a strategy to avoid formation of amyloid fibrils

      PROTEIN SCIENCE
    91. Weiss, GA; Wells, JA; Sidhu, SS
      Mutational analysis of the major coat protein of M13 identifies residues that control protein display

      PROTEIN SCIENCE
    92. Burton, RE; Hunt, JA; Fierke, CA; Oas, TG
      Novel disulfide engineering in human carbonic anhydrase II using the PAIRWISE side-chain geometry database

      PROTEIN SCIENCE
    93. Vindigni, A; Winfield, M; Ayala, YM; Di Cera, E
      Role of residue Y99 in tissue plasminogen activator

      PROTEIN SCIENCE
    94. Rath, A; Davidson, AR
      The design of a hyperstable mutant of the Abp1p SH3 domain by sequence alignment analysis

      PROTEIN SCIENCE
    95. Lehmann, M; Lopez-Ulibarri, R; Loch, C; Viarouge, C; Wyss, M; Van Loon, APGM
      Exchanging the active site between phytases for altering the functional properties of the enzyme

      PROTEIN SCIENCE
    96. Engel, J; Kammerer, RA
      What are oligomerization domains good for?

      MATRIX BIOLOGY
    97. Nolting, B; Andert, K
      Mechanism of protein folding

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    98. Lehtio, J; Teeri, TT; Nygren, PA
      Alpha-amylase inhibitors selected from a combinatorial library of a cellulose binding domain scaffold

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    99. Pitera, JW; Kollman, PA
      Exhaustive mutagenesis in silico: Multicoordinate free energy calculationson proteins and peptides

      PROTEINS-STRUCTURE FUNCTION AND GENETICS
    100. Woodley, JM
      Advances in enzyme technology - UK contributions

      HISTORY OF MODERN BIOTECHNOLOLGY II


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Documento generato il 29/10/20 alle ore 11:18:42