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Usefulness of biochemical markers of bone turnover in assessing response to the treatment of Paget's disease
BONE
Synthesis and post-translational processing of surfactant protein C
PEDIATRIC PATHOLOGY & MOLECULAR MEDICINE
Biosynthesis, processing and secretion of von Willebrand factor: biological implications
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
Type 2 von Willebrand disease causing defective von Willebrand factor-dependent platelet function
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
Fetal bone metabolism in normal and rhesus isoimmunised pregnancies
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
An inner membrane platform in the type II secretion machinery of Gram-negative bacteria
EMBO REPORTS
Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma)
ARTHRITIS RESEARCH
Cathepsins X and B display distinct activity profiles that can be exploited for inhibitor design
BIOLOGICAL CHEMISTRY
Folding incompetence of cathepsin L-like cysteine proteases may be compensated by the highly conserved, domain-building N-terminal extension of the proregion
BIOLOGICAL CHEMISTRY
Oesophageal pressure-cross-sectional area distributions and secondary peristalsis in relation to subclassification of systemic sclerosis
NEUROGASTROENTEROLOGY AND MOTILITY
The balance between collagen synthesis and degradation in diffuse lung disease
SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES
The relationship between abdominal aortic aneurysm distensibility and serum markers of elastin and collagen metabolism
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
Substrate-induced activation of a trapped IMC-medateed protein folding intermediate
NATURE STRUCTURAL BIOLOGY
Structures and functions of precursors of bacterial proteases
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
Deletions and duplications of Gly-Xaa-Yaa triplet repeats in the triple helical domains of type I collagen chains disrupt helix formation and result in several types of osteogenesis imperfecta
HUMAN MUTATION
Type IIA procollagen: Expression in developing chicken limb cartilage and human osteoarthritic articular cartilage
DEVELOPMENTAL DYNAMICS
Type IIA procollagen in development of the human intervertebral disc: Regulated expression of the NH2-propeptide by enzymic processing reveals a unique developmental pathway
DEVELOPMENTAL DYNAMICS
Refolding and purification of yeast carboxypeptidase Y expressed as inclusion bodies in Escherichia coli
PROTEIN EXPRESSION AND PURIFICATION
Demonstration in yeast of the function of BP-80, a putative plant vacuolarsorting receptor
PLANT CELL
Molecular cloning of kpcA gene encoding a Kex2p-like endoprotease from Aspergillus nidulans
MOLECULES AND CELLS
Extracellular matrix in development of the early embryo
MICRON
STEM/TEM studies of collagen fibril assembly
MICRON
Folding defects in fibrillar collagens
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
Serum pro-collagen III peptide levels are related to lobular necrosis in untreated patients with chronic hepatitis C
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Vasoactive peptides and procollagen propeptides in patients with hypertension in relation to cardiac hypertrophy and diastolic heart failure: design of the study and patient characteristics
JOURNAL OF HUMAN HYPERTENSION
Differential expression of two exons of the alpha 1(XI) collagen gene (Col11a1) in the mouse embryo
MATRIX BIOLOGY
GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding
GROWTH FACTORS
Canine COL1A2 mutation resulting in C-terminal truncation of pro-alpha 2(I) and severe osteogenesis imperfecta
JOURNAL OF BONE AND MINERAL RESEARCH
Functional impact of human collagen alpha 2(XI) gene polymorphism in pathogenesis of ossification of the posterior longitudinal ligament of the spine
JOURNAL OF BONE AND MINERAL RESEARCH
Serum amino-terminal propeptide of type III procollagen and 7S domain of type IV collagen correlate with hepatic iron concentration in patients with chronic hepatitis C following alpha-interferon therapy
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
A new and accurate prediction model for growth response to growth hormone treatment in children with growth hormone deficiency
EUROPEAN JOURNAL OF ENDOCRINOLOGY
pN collagen type III within tendon grafts used for anterior cruciate ligament reconstruction
JOURNAL OF ORTHOPAEDIC RESEARCH
Healing of full-thickness tears of avian supracoracoid tendons: in situ hybridization of alpha 1(I) and alpha 1(III) procollagen mRNA
JOURNAL OF ORTHOPAEDIC RESEARCH
Effect of sucrose on collagen metabolism in keloid, hypertrophic scar, andgranulation tissue fibroblast cultures
WORLD JOURNAL OF SURGERY
In vivo evaluation of In-111-DTPA-N-TIMP-2 in Kaposi sarcoma associated with HIV infection
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
Abnormal propeptide processing resulting in the presence of two abnormal species of protein C in plasma - Characterization of the dysfunctional protein C Padua(3) (Protein CR-1L/propeptide)
THROMBOSIS AND HAEMOSTASIS
Von Willebrand factor propeptide in vascular disorders
THROMBOSIS AND HAEMOSTASIS
Genetic predisposition to bleeding during oral anticoagulant therapy: Evidence for common founder mutations (FIXVal-10 and FIXThr-10) and an independent CpG hotspot mutation (FIXThr-10)
THROMBOSIS AND HAEMOSTASIS
Secretion of human growth hormone by the food-grade bacterium Staphylococcus carnosus requires a propeptide irrespective of the signal peptide used
ARCHIVES OF MICROBIOLOGY
Activation of latent protease function of Pro-HK2, but not Pro-PSA, involves autoprocessing
PROSTATE
Clinical aspects of hypertensive myocardial fibrosis
CURRENT OPINION IN CARDIOLOGY
Postoperative PINP in serum reflects metastatic potential and poor survival in node-positive breast cancer
ANTICANCER RESEARCH
Metastatic colorectal cancer stimulates collagen synthesis by fibroblasts
ANTICANCER RESEARCH
Biochemical assessment of myocardial fibrosis in hypertensive heart disease
HYPERTENSION
Increased bone turnover is associated with protein and energy metabolism in adolescents with sickle cell anemia
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
The C-terminal tetrapeptide of phaseolin is sufficient to target green fluorescent protein to the vacuole
JOURNAL OF PLANT PHYSIOLOGY
Baseline expression and effect of TGF-beta 1 on type I and III collagen mRNA and protein synthesis in human odontoblasts and pulp cells in vitro
CALCIFIED TISSUE INTERNATIONAL
Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alpha 1(I) and TIMP-1
JOURNAL OF HEPATOLOGY
Type I collagen turnover and cross-linking are increased in irradiated skin of breast cancer patients
RADIOTHERAPY AND ONCOLOGY
Identification of peptides inhibitory to recombinant cysteine proteinase, CPB, of Leishmania mexicana
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Plasma levels of cellular fibronectin in diabetes
DIABETES CARE
Double heterozygosity for pseudoachondroplasia and spondyloepiphyseal dysplasia congenita
AMERICAN JOURNAL OF MEDICAL GENETICS
Therapeutic time-window of a group IIA phospholipase A(2) inhibitor in rabbit acute lung injury: Correlation with lung surfactant protection
CRITICAL CARE MEDICINE
Collagen metabolites in the peripheral and splanchnic circulation of patients with Crohn disease
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
Biochemical markers of bone metabolism in growing thoroughbreds: a longitudinal study
RESEARCH IN VETERINARY SCIENCE
The internal propeptide of the ricin precursor carries a sequence-specificdeterminant for vacuolar sorting
PLANT PHYSIOLOGY
The endomembrane system and the problem of protein sorting
PLANT PHYSIOLOGY
Isolation of a putative receptor for KDEL-tailed cysteine proteinase (SH-EP) from cotyledons of Vigna mungo seedlings
PLANT AND CELL PHYSIOLOGY
Markers of type I and type III collagen turnover, insulin-like growth factors, and their binding proteins in cord plasma of small premature infants: Relationships with fetal growth, gestational age, preeclampsia, and antenatal glucocorticoid treatment
PEDIATRIC RESEARCH
A recessive form of the Ehlers-Danlos syndrome caused by tenascin-X deficiency.
NEW ENGLAND JOURNAL OF MEDICINE
Crystal structure of the precursor of galactose oxidase: An unusual self-processing enzyme
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Pyridinoline cross-linked carboxyterminal telopeptide of type I collagen as a useful marker for monitoring metastatic bone activity in men with prostate cancer
JOURNAL OF UROLOGY
Training-induced changes in peritendinous type I collagen turnover determined by microdialysis in humans
JOURNAL OF PHYSIOLOGY-LONDON
Disruption of one intra-chain disulphide bond in the carboxyl-terminal propeptide of the pro alpha 1(I) chain of type I procollagen permits slow assembly and secretion of overmodified, but stable procollagen trimers and results in mild osteogenesis imperfecta
JOURNAL OF MEDICAL GENETICS
Biosynthesis of surfactant protein C: characterization of aggresome formation by EGFP chimeras containing propeptide mutants lacking conserved cysteine residues
JOURNAL OF CELL SCIENCE
Collagenous sequence governs the trimeric assembly of collagen XII
JOURNAL OF BIOLOGICAL CHEMISTRY
Maturation of Pseudomonas aeruginosa elastase - Formation of the disulfidebonds
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of fibrosurfin, an interfibrillar component of sea urchincatch connective tissues
JOURNAL OF BIOLOGICAL CHEMISTRY
The Pro domain of beta-secretase does not confer strict zymogen-like properties but does assist proper folding of the protease domain
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of internal autoproteolytic cleavage sites within the prosegments of recombinant procathepsin B and procathepsin S - Contribution of aplausible unimolecular autoproteolytic event for the processing of zymogens belonging to the papain family
JOURNAL OF BIOLOGICAL CHEMISTRY
Bombyx cysteine proteinase inhibitor (BCPI) homologous to propeptide regions of cysteine proteinases is a strong, selective inhibitor of cathepsin L-like cysteine proteinases
JOURNAL OF BIOCHEMISTRY
Accelerated refolding of subtilisin BPN ' by tertiary-structure-forming mutants of its propeptide
JOURNAL OF BIOCHEMISTRY
Improved autoprocessing efficiency of mutant subtilisins E with altered specificity by engineering of the pro-region
JOURNAL OF BIOCHEMISTRY
Cellular trafficking in trypanosomatids: a new target for therapies?
INTERNATIONAL JOURNAL FOR PARASITOLOGY
Mechanism of Kex2p inhibition by its proregion
FEBS LETTERS
Functional analysis of the propeptides of subtilisin E and aqualysin I as intramolecular chaperones
FEBS LETTERS
C-terminal propeptide of the Caldariomyces fumago chloroperoxidase: an intramolecular chaperone?
FEBS LETTERS
Membrane type 1 matrix metalloproteinase and gelatinase A synergistically degrade type 1 collagen in a cell model
FEBS LETTERS
Type I collagen markers in cord serum of appropriate vs. small for gestational age infants born during the second half of pregnancy
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
A basic residue at position 36p of the propeptide is not essential for thecorrect folding and subsequent autocatalytic activation of prochymosin
EUROPEAN JOURNAL OF BIOCHEMISTRY
The pro-sequence facilitates folding of human nerve growth factor from Escherichia coli inclusion bodies
EUROPEAN JOURNAL OF BIOCHEMISTRY
Effect of electromagnetic fields on bone mineral density and biochemical markers of bone turnover in osteoporosis: A single-blind, randomized pilot study
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
Combined effects of estrogen and progesterone on the anterior cruciate ligament
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
Diurnal variations in serum and urine markers of type I and type III collagen turnover in children
CLINICAL CHEMISTRY
Pravastatin therapy increases procollagen IN-terminal propeptide (PINP), amarker of bone formation in post-menopausal women
CLINICA CHIMICA ACTA
The value of amino-terminal propeptide of type III procollagen in routine screening for methotrexate-induced liver fibrosis: a 10-year follow-up
BRITISH JOURNAL OF DERMATOLOGY
Cathepsins X and B can be differentiated through their respective mono- and dipeptidyl carboxypeptidase activities
BIOCHEMISTRY
Tethered processivity of the vitamin K-dependent carboxylase: Factor IX isefficiently modified in a mechanism which distinguishes Gla's from Glu's and which accounts for comprehensive carboxylation in vivo
BIOCHEMISTRY
Characterization of the maturation of human pro-apolipoprotein A-I in an in vitro model
BIOCHEMISTRY
Alteration of inhibitory properties of Pleurotus ostreatus proteinase A inhibitor 1 by mutation of its C-terminal region
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis
ARTHRITIS AND RHEUMATISM
Matrix turnover in human cartilage repair tissue in autologous chondrocyteimplantation
ARTHRITIS AND RHEUMATISM
Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after anterior myocardial infarction
AMERICAN HEART JOURNAL
Serum and urine markers of bone metabolism during the year after hip fracture
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
An uncommon cause of severe bleeding during phenprocoumon treatment
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT
Components of biological variation of biochemical markers of bone turnoverin Paget's bone disease
BONE
Bone mineral density and serum levels of aminoterminal propeptides and cross-linked N-telopeptides of type I collagen in elderly men
BONE
Sorting of soluble proteins in the secretory pathway of plants
CURRENT OPINION IN PLANT BIOLOGY
Vacuoles and prevacuolar compartments
CURRENT OPINION IN PLANT BIOLOGY
The efficacy of biochemical markers in patients with ossification of posterior longitudinal ligament of the spine
SPINAL CORD