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Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire
IMMUNITY
Germinal center reaction
CURRENT OPINION IN HEMATOLOGY
The immunology of Epstein-Barr virus infection
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
Mechanisms of cytokine synergy essential for vaccine protection against viral challenge
INTERNATIONAL IMMUNOLOGY
Canonical germinal center B cells may not dominate the memory response to antigenic challenge
INTERNATIONAL IMMUNOLOGY
CD8(+) cytotoxic T lymphocyte responses to lentiviruses and herpesviruses
CURRENT OPINION IN IMMUNOLOGY
In vivo tracking of tumor-specific T cells
CURRENT OPINION IN IMMUNOLOGY
Stimulation of HIV gp120-specific cytolytic T lymphocyte responses in vitro and in vivo using a detoxified pertussis toxin vector
AIDS RESEARCH AND HUMAN RETROVIRUSES
Immunologic and virologic analyses of an acutely HIV type 1-infected patient with extremely rapid disease progression
AIDS RESEARCH AND HUMAN RETROVIRUSES
Spontaneous formation of germinal centers in autoimmune mice
JOURNAL OF LEUKOCYTE BIOLOGY
Kinetics of the T-cell receptor CD4 and CD8 V beta repertoire in HIV-1 vertically infected infants early treated with HAART
AIDS
Vaccination with autologous dendritic cells: from experimental autoimmune encephalomyelitis to multiple sclerosis
JOURNAL OF NEUROIMMUNOLOGY
Testing the reverse transcriptase model of somatic mutation
MOLECULAR IMMUNOLOGY
A role for secondary V(D)J recombination in oncogenic chromosomal translocations?
ADVANCES IN CANCER RESEARCH, VOL 81
Skewed maturation of memory HIV-specific CD8 T lymphocytes
NATURE
Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251-and simian-human immunodeficiency virus KU2-infected macaques
JOURNAL OF VIROLOGY
Emergence and kinetics of simian immunodeficiency virus-specific CD8(+) T cells in the intestines of macaques during primary infection
JOURNAL OF VIROLOGY
Toward quantitative simulation of germinal center dynamics: Biological andmodeling insights from experimental validation
JOURNAL OF THEORETICAL BIOLOGY
Recycling probability and dynamical properties of germinal center reactions
JOURNAL OF THEORETICAL BIOLOGY
Somatic hypermutation and selection of B cells in thymic germinal centers responding to acetylcholine receptor in myasthenia gravis
JOURNAL OF IMMUNOLOGY
Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus
JOURNAL OF IMMUNOLOGY
Development and maintenance of a B220(-) memory B cell compartment
JOURNAL OF IMMUNOLOGY
A pivotal role for DNase I-sensitive regions 3b and/or 4 in the induction of somatic hypermutation of IgH genes
JOURNAL OF IMMUNOLOGY
Extrafollicular plasmablast B cells play a key role in carrying retroviralinfection to peripheral organs
JOURNAL OF IMMUNOLOGY
A coordinated change in chemokine responsiveness guides plasma cell movements
JOURNAL OF EXPERIMENTAL MEDICINE
Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
JOURNAL OF EXPERIMENTAL MEDICINE
Rewiring of CD40 is necessary for delivery of rescue signals to B cells ingerminal centres and subsequent entry into the memory pool
IMMUNOLOGY
B cells activated via CD40 and IL-4 undergo a division burst but require continued stimulation to maintain division, survival and differentiation
EUROPEAN JOURNAL OF IMMUNOLOGY
Changing responsiveness to chemokines allows medullary plasmablasts to leave lymph nodes
EUROPEAN JOURNAL OF IMMUNOLOGY
Regulation of T-dependent humoral responses: The alternate paradigm
CURRENT SCIENCE
Increase in tonsillar germinal centre B-1 cell numbers in IgA nephropathy (IgAN) patients and reduced susceptibility to Fas-mediated apoptosis
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Inappropriate expression of IgD from a transgene inhibits the function of antigen-specific memory B cells
CELLULAR IMMUNOLOGY
HIV-1 transmission and acute HIV-1 infection
BRITISH MEDICAL BULLETIN
Asymptomatic primary Epstein-Barr virus infection occurs in the absence ofblood T-cell repertoire perturbations despite high levels of systemic viral load
BLOOD
CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus,and cytomegalovirus lack molecules for homing to lymphoid sites of infection
BLOOD
B-cell development in progressively transformed germinal centers: similarities and differences compared with classical germinal centers and lymphocyte-predominant Hodgkin disease
BLOOD
Characterization of the T cell receptor repertoire in patients with commonvariable immunodeficiency: Oligoclonal expansion of CD8(+) T cells
CLINICAL IMMUNOLOGY
Cell-cell interactions in synovitis - Interactions between T cells and B cells in rheumatoid arthritis
ARTHRITIS RESEARCH
Affinity maturation in the B-cell response to antigen
IMMUNOLOGIST
The contribution of somatic hypermutation to the diversity of serum immunoglobulin: Dramatic increase with age
IMMUNITY
B-cell memory and the persistence of antibody responses
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
Immunopathogenesis of HIV-1 infection
CLINICS IN DERMATOLOGY
Chemokines and dendritic cell traffic
JOURNAL OF CLINICAL IMMUNOLOGY
Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection
AIDS
Patterns of CD8 T cell clonal dominance in response to change in antiretroviral therapy in HIV-infected children
AIDS
Relative roles of somatic and darwinian evolution in shaping the antibody response
IMMUNOLOGIC RESEARCH
Dissecting affinity maturation: a model explaining selection of antibody-forming cells and memory B cells in the germinal centre
IMMUNOLOGY TODAY
Co-stimulation and selection for T-cell help for germinal centres: The role of CD28 and OX40
IMMUNOLOGY TODAY
Immunoglobulin gene joints compensate for reduced on-rates imposed by somatic mutations in a V-H gene
MOLECULAR IMMUNOLOGY
Kinetic and genetic bases for the heteroclitic recognition of mouse cytochrome c by mouse anti-pigeon cytochrome c monoclonal antibodies
MOLECULAR IMMUNOLOGY
A two-phase model of B-cell activation
IMMUNOLOGICAL REVIEWS
Dynamics of one-pass germinal center models: Implications for affinity maturation
BULLETIN OF MATHEMATICAL BIOLOGY
Immunological evaluation of human immunodeficiency virus infected individuals by flow cytometry
MEMORIAS DO INSTITUTO OSWALDO CRUZ
Differential dynamics of CD4(+) and CD8(+) T-lymphocyte proliferation and activation in acute simian immunodeficiency virus infection
JOURNAL OF VIROLOGY
Towards a quantitative model of immunogenicity: Counting pathways in sequence space
JOURNAL OF THEORETICAL BIOLOGY
Transient T cell receptor beta-chain variable region-specific expansions of CD4(+) and CD8(+) T cells during the early phase of pediatric human immunodeficiency virus infection: Characterization of expanded cell populations by T cell receptor phenotyping
JOURNAL OF INFECTIOUS DISEASES
Changing patterns of dominant TCR usage with maturation of an EBV-specificcytotoxic T cell response
JOURNAL OF IMMUNOLOGY
Impaired affinity maturation in Cr2(-/-) mice is rescued by adjuvants without improvement in germinal center development
JOURNAL OF IMMUNOLOGY
Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection
JOURNAL OF IMMUNOLOGY
The role of CD4(+) T cell help and CD40 ligand in the in vitro expansion of HIV-1-specific memory cytotoxic CD8(+) T cell responses
JOURNAL OF IMMUNOLOGY
Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo
JOURNAL OF IMMUNOLOGY
Analysis of the virus-specific and nonspecific B cell response to a persistent B-lymphotropic gammaherpesvirus
JOURNAL OF IMMUNOLOGY
Identification of murine germinal center B cell subsets defined by the expression of surface isotypes and differentiation antigens
JOURNAL OF IMMUNOLOGY
Rapid identification of local T cell expansion in inflammatory organ diseases by flow cytometric T cell receptor V beta analysis
JOURNAL OF IMMUNOLOGICAL METHODS
Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival
JOURNAL OF EXPERIMENTAL MEDICINE
Macrophage inflammatory protein 3 alpha is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors
JOURNAL OF EXPERIMENTAL MEDICINE
Virus-induced maturation and activation of autoreactive memory B cells
JOURNAL OF EXPERIMENTAL MEDICINE
Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children
JOURNAL OF EXPERIMENTAL MEDICINE
Antigen-specific B cell memory: Expression and replenishment of a novel B220(-) memory B cell compartment
JOURNAL OF EXPERIMENTAL MEDICINE
bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells
JOURNAL OF EXPERIMENTAL MEDICINE
Germinal centers without T cells
JOURNAL OF EXPERIMENTAL MEDICINE
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern
JOURNAL OF EXPERIMENTAL MEDICINE
CD8(+) T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained
EUROPEAN JOURNAL OF IMMUNOLOGY
The thalidomide analogue CC-3052 inhibits HIV-1 and tumour necrosis factor-alpha (TNF-alpha) expression in acutely and chronically infected cells in vitro
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Fas-mediated apoptosis eliminates B cells that acquire self-reactivity during the germinal center response to NP
CELLULAR IMMUNOLOGY
Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor beta chain repertoire and reduces the level of T-cell oligoclonality
BLOOD
Telomere loss in peripheral blood mononuclear cells may be moderately accelerated during highly active antiretroviral therapy (HAART)
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
The importance of lymphocyte trafficking in regulating blood lymphocyte levels during HIV and SIV infections
SEMINARS IN IMMUNOLOGY
7 beta-OH-DHEA counteracts dexamethasone induced suppression of primary immune response in murine spleenocytes
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
B cell memory and the long-lived plasma cell
CURRENT OPINION IN IMMUNOLOGY
V(D)J hypermutation and receptor revision: coloring outside the lines
CURRENT OPINION IN IMMUNOLOGY
Selection in a T-dependent primary humoral response: new insights from polypeptide models
APMIS
Positive and negative regulation of the myeloid dendritic cell lineage
JOURNAL OF LEUKOCYTE BIOLOGY
T cell receptor usage in infectious disease
SPRINGER SEMINARS IN IMMUNOPATHOLOGY
Contributions of CD4(+), CD8(+), and CD4(+)CD8(+) T cells to skewing within the peripheral T cell receptor beta chain repertoire of healthy macaques
HUMAN IMMUNOLOGY
Anti-DNA autoantibodies and systemic lupus erythematosus
PHARMACOLOGY & THERAPEUTICS
A quantitative, single-cell PCR analysis of an antigen-specific TCR repertoire selected during an in vivo CD8 response: direct evidence for a wide range of clone sizes with uniform tissue distribution
MOLECULAR IMMUNOLOGY
Cytotoxic T lymphocytes and viral evolution in primary HIV-I infection
CLINICAL SCIENCE
Broad, intense anti-human immunodeficiency virus (HIV) ex vivo CD8(+) responses in HIV type 1-infected patients: Comparison with anti-Epstein-Barr virus responses and changes during antiretroviral therapy
JOURNAL OF VIROLOGY
Simian immunodeficiency virus disease course is predicted by the extent ofvirus replication during primary infection
JOURNAL OF VIROLOGY
Hierarchal utilization of different T-cell receptor V beta gene segments in the CD8(+)-T-cell response to an immunodominant Moloney leukemia virus-encoded epitope in vivo
JOURNAL OF VIROLOGY
A mathematical model on germinal center kinetics and termination
JOURNAL OF IMMUNOLOGY
Reconciling repertoire shift with affinity maturation: The role of deleterious mutations
JOURNAL OF IMMUNOLOGY
Clonal dominance patterns of CD8 T cells in relation to disease progression in HIV-infected children
JOURNAL OF IMMUNOLOGY
Biased TCR repertoire in HIV-1-infected patients due to clonal expansion of HIV-1-reverse transcriptase-specific CTL clones
JOURNAL OF IMMUNOLOGY
A member of the dendritic cell family that enters B cell follicles and stimulates primary antibody responses identified by a mannose receptor fusion protein
JOURNAL OF EXPERIMENTAL MEDICINE
Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-x(L) transgenic mice
JOURNAL OF EXPERIMENTAL MEDICINE
Lymph node germinal centers form in the absence of follicular dendritic cell networks
JOURNAL OF EXPERIMENTAL MEDICINE
MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells
JOURNAL OF EXPERIMENTAL MEDICINE
The composition of a primary T cell response is largely determined by the timing of recruitment of individual T cell clones
JOURNAL OF EXPERIMENTAL MEDICINE