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1. Dessauer, CW
   Kinetic analysis of the action of P-site analogs
   G PROTEIN PATHWAYS: PT C, EFFECTOR MECHANISMS
   
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2. Rowland, TL; McHugh, SM; Deighton, J; Ewan, PW; Dearman, RJ; Kimber, I
   Differential effect of thalidomide and dexamethasone on the transcription factor NF-kappa B
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3. Owens, TD; Semple, JE
   Atom-economical synthesis of the N(10)-C(17) fragment of cyclotheonamides via a novel passerini reaction-deprotection-acyl migration strategy
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   T.D. Owens e J.E. Semple, "Atom-economical synthesis of the N(10)-C(17) fragment of cyclotheonamides via a novel passerini reaction-deprotection-acyl migration strategy", ORG LETT, 3(21), 2001, pp. 3301-3304
4. Tamaki, K; Shotwell, JB; White, RD; Drutu, I; Petsch, DT; Nheu, TV; He, H; Hirokawa, Y; Maruta, H; Wood, JL
   Efficient syntheses of novel C2 '-alkylated (+/-)-K252a analogues
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5. Linker-Israeli, M; Elstner, E; Klinenberg, JR; Wallace, DJ; Koeffler, HP
   Vitamin D-3 and its synthetic analogs inhibit the spontaneous in vitro immunoglobulin production by SLE-derived PBMC
   CLINICAL IMMUNOLOGY
   
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6. Bondzio, A; Abraham-Podgornik, A; Blankenstein, P; Risse, S
   Involvement of intracellular Ca2+ in the regulation of bovine leukemia virus expression
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7. Lung, FDT; Lang, YQ; King, CR; Varady, J; Wu, XW; Wang, S; Roller, PP
   Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain
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8. Thorson, JS; Hosted, TJ; Jiang, JQ; Biggins, JB; Ahlert, J
   Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites
   CURRENT ORGANIC CHEMISTRY
   
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9. Gobran, LI; Rooney, SA
   Regulation of SP-B and SP-C secretion in rat type II cells in primary culture
   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
   
   L.I. Gobran e S.A. Rooney, "Regulation of SP-B and SP-C secretion in rat type II cells in primary culture", AM J P-LUNG, 281(6), 2001, pp. L1413-L1419
10. Hwang, DJ; Kim, SN; Choi, JH; Lee, YS
    Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors
    BIOORGANIC & MEDICINAL CHEMISTRY
    
    D.J. Hwang et al., "Dicaffeoyl- or digalloyl pyrrolidine and furan derivatives as HIV integrase inhibitors", BIO MED CH, 9(6), 2001, pp. 1429-1437
11. Groutas, WC; He, S; Kuang, RZ; Ruan, S; Tu, J; Chan, HK
    Inhibition of serine proteases by functionalized sulfonamides coupled to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold
    BIOORGANIC & MEDICINAL CHEMISTRY
    
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12. Venkatachalam, TK; Sudbeck, EA; Mao, C; Uckun, FM
    Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    T.K. Venkatachalam et al., "Anti-HIV activity of aromatic and heterocyclic thiazolyl thiourea compounds", BIOORG MED, 11(4), 2001, pp. 523-528
13. Robina, I; Moreno-Vargas, AJ; Fernandez-Bolanos, JG; Fuentes, J; Demange, R; Vogel, P
    New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    I. Robina et al., "New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives", BIOORG MED, 11(18), 2001, pp. 2555-2559
14. Schiodt, CB; Buchardt, J; Terp, GE; Christensen, U; Brink, M; Larsen, YB; Meldal, M; Foged, NT
    Phosphinic peptide inhibitors of macrophage metalloelastase (MMP-12). Selectivity and mechanism of binding
    CURRENT MEDICINAL CHEMISTRY
    
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15. Garcia-Echeverria, C
    Antagonists of the Src homology 2 (SH2) domains of Grb2, Src, Lck and ZAP-70
    CURRENT MEDICINAL CHEMISTRY
    
    C. Garcia-Echeverria, "Antagonists of the Src homology 2 (SH2) domains of Grb2, Src, Lck and ZAP-70", CURR MED CH, 8(13), 2001, pp. 1589-1604
16. Lee, CC; Huang, TS
    A novel topoisomerase II poison GL331 preferentially induces DNA cleavage at (C/G)T sites and can cause telomere DNA damage
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17. d'Angelo, J; Mouscadet, JF; Desmaele, D; Zouhiri, F; Leh, H
    HIV-1 integrase: the next target for AIDS therapy?
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18. Waldmann, H; Thutewohl, M
    Ras-farnesyltransferase-inhibitors as promising anti-tumor drugs
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19. Kirk, CJ; Harris, RM; Wood, DM; Waring, RH; Hughes, PJ
    Do dietary phytoestrogens influence susceptibility to hormone-dependent cancer by disrupting the metabolism of endogenous oestrogens?
    BIOCHEMICAL SOCIETY TRANSACTIONS
    
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20. Cousson, A
    Pharmacological evidence for the implication of both cyclic GMP-dependent and -independent transduction pathways within auxin-induced stomatal opening in Commelina communis (L.)
    PLANT SCIENCE
    
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21. Abe, I; Kashiwagi, Y; Noguchi, H; Tanaka, T; Ikeshiro, Y; Kashiwada, Y
    Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase
    JOURNAL OF NATURAL PRODUCTS
    
    I. Abe et al., "Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase", J NAT PROD, 64(8), 2001, pp. 1010-1014
22. Matsunaga, S; Nishimura, S; Fusetani, N
    Two new antimicrobial lysoplasmanylinositols from the marine sponge Theonella swinhoei
    JOURNAL OF NATURAL PRODUCTS
    
    S. Matsunaga et al., "Two new antimicrobial lysoplasmanylinositols from the marine sponge Theonella swinhoei", J NAT PROD, 64(6), 2001, pp. 816-818
23. Husoy, T; Cruciani, V; Sanner, T; Mikalsen, SO
    Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 fibroblasts: minor role of protein kinase C beta I and mu
    CARCINOGENESIS
    
    T. Husoy et al., "Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 fibroblasts: minor role of protein kinase C beta I and mu", CARCINOGENE, 22(2), 2001, pp. 221-231
24. D'Amato, RJ; Lentzsch, S; Anderson, KC; Rogers, MS
    Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma
    SEMINARS IN ONCOLOGY
    
    R.J. D'Amato et al., "Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma", SEMIN ONCOL, 28(6), 2001, pp. 597-601
25. Stirling, D
    Thalidomide: A novel template for anticancer drugs
    SEMINARS IN ONCOLOGY
    
    D. Stirling, "Thalidomide: A novel template for anticancer drugs", SEMIN ONCOL, 28(6), 2001, pp. 602-606
26. Coughtrie, MWH; Johnston, LE
    Interactions between dietary chemicals and human sulfotransferases - Molecular mechanisms and clinical significance
    DRUG METABOLISM AND DISPOSITION
    
    M.W.H. Coughtrie e L.E. Johnston, "Interactions between dietary chemicals and human sulfotransferases - Molecular mechanisms and clinical significance", DRUG META D, 29(4), 2001, pp. 522-528
27. Holz-Smith, SL; Sun, IC; Jin, L; Matthews, TJ; Lee, KH; Chen, CH
    Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIVactivity of the betulinic acid derivative IC9564
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    
    S.L. Holz-Smith et al., "Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIVactivity of the betulinic acid derivative IC9564", ANTIM AG CH, 45(1), 2001, pp. 60-66
28. Bossart, KN; Wang, LF; Eaton, BT; Broder, CC
    Functional expression and membrane fusion tropism of the envelope glycoproteins of Hendra virus
    VIROLOGY
    
    K.N. Bossart et al., "Functional expression and membrane fusion tropism of the envelope glycoproteins of Hendra virus", VIROLOGY, 290(1), 2001, pp. 121-135
29. McGinnes, LW; Sergel, T; Chen, H; Hamo, L; Schwertz, S; Li, DH; Morrison, TG
    Mutational analysis of the membrane proximal heptad repeat of the Newcastle disease virus fusion protein
    VIROLOGY
    
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30. McGinnes, L; Sergel, T; Reitter, J; Morrison, T
    Carbohydrate modifications of the NDV fusion protein heptad repeat domainsinfluence maturation and fusion activity
    VIROLOGY
    
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31. Dutch, RE; Hagglund, RN; Nagel, MA; Paterson, RG; Lamb, RA
    Paramyxovirus fusion (F) protein: A conformational change on cleavage activation
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32. Zouhiri, F; Desmaele, D; d'Angelo, J; Ourevitch, M; Mouscadet, JF; Leh, H; Le Bret, M
    HIV-1 replication inhibitors of the styrylquinoline class: incorporation of a masked diketo acid pharmacophore
    TETRAHEDRON LETTERS
    
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33. Slanina, J; Taborska, E; Bochorakova, H; Slaninova, I; Humpa, O; Robinson, WE; Schram, KH
    New and facile method of preparation of the anti-HIV-1 agent, 1,3-dicaffeoylquinic acid
    TETRAHEDRON LETTERS
    
    J. Slanina et al., "New and facile method of preparation of the anti-HIV-1 agent, 1,3-dicaffeoylquinic acid", TETRAHEDR L, 42(19), 2001, pp. 3383-3385
34. Root, MJ; Kay, MS; Kim, PS
    Protein design of an HIV-1 entry inhibitor
    SCIENCE
    
    M.J. Root et al., "Protein design of an HIV-1 entry inhibitor", SCIENCE, 291(5505), 2001, pp. 884-888
35. Marquina, S; Maldonado, N; Garduno-Ramirez, ML; Aranda, E; Villarreal, ML; Navarro, V; Bye, R; Delgado, G; Alvarez, L
    Bioactive oleanolic acid saponins and other constituents from the roots ofViguiera decurrens
    PHYTOCHEMISTRY
    
    S. Marquina et al., "Bioactive oleanolic acid saponins and other constituents from the roots ofViguiera decurrens", PHYTOCHEM, 56(1), 2001, pp. 93-97
36. D'Acquisto, F; Ianaro, A; Ialenti, A; Maffia, P; Maiuri, MC; Carnuccio, R
    Transcription factor decoy oligodeoxynucleotides to nuclear factor-kappa Binhibit reverse passive Arthus reaction in rat
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    
    F. D'Acquisto et al., "Transcription factor decoy oligodeoxynucleotides to nuclear factor-kappa Binhibit reverse passive Arthus reaction in rat", N-S ARCH PH, 364(5), 2001, pp. 422-429
37. Yi, M; Ruoslahti, E
    A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    M. Yi e E. Ruoslahti, "A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis", P NAS US, 98(2), 2001, pp. 620-624
38. Sergel, TA; McGinnes, LW; Morrison, TG
    Mutations in the fusion peptide and adjacent heptad repeat inhibit foldingor activity of the Newcastle disease virus fusion protein
    JOURNAL OF VIROLOGY
    
    T.A. Sergel et al., "Mutations in the fusion peptide and adjacent heptad repeat inhibit foldingor activity of the Newcastle disease virus fusion protein", J VIROLOGY, 75(17), 2001, pp. 7934-7943
39. Hillier, MC; Davidson, JP; Martin, SF
    Cyclopropane-derived peptidomimetics. Design, synthesis, and evaluation ofnovel Ras farnesyltransferase inhibitors
    JOURNAL OF ORGANIC CHEMISTRY
    
    M.C. Hillier et al., "Cyclopropane-derived peptidomimetics. Design, synthesis, and evaluation ofnovel Ras farnesyltransferase inhibitors", J ORG CHEM, 66(5), 2001, pp. 1657-1671
40. Salmon-Chemin, L; Buisine, E; Yardley, V; Kohler, S; Debreu, MA; Landry, V; Sergheraert, C; Croft, SL; Krauth-Siegel, RL; Davioud-Charvet, E
    2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity
    JOURNAL OF MEDICINAL CHEMISTRY
    
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41. Clare, BW; Scozzafava, A; Supuran, CT
    Protease inhibitors: Synthesis of a series of bacterial collagenase inhibitors of the sulfonyl amino acyl hydroxamate type
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42. Charitos, C; Kokotos, G; Tzougraki, C
    Bifunctional coumarin derivatives in solution and solid phase synthesis offluorogenic enzyme substrates
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43. LaRochelle, O; Gagne, V; Charron, J; Soh, JW; Seguin, C
    Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions
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44. Kosuge, S; Maekawa, T; Saito, C; Tanaka, T; Kouno, I; Ohtsuki, K
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45. Kohda, Y; Gemba, M
    Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices
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46. Blaser, A; Reymond, JL
    Aminocyclopentitol inhibitors of alpha-L-fucosidases
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47. Cruciani, V; Husoy, T; Mikalsen, SO
    Pharmacological evidence for system-dependent involvement of protein kinase C isoenzymes in phorbol ester-suppressed gap junctional communication
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48. Hisatake, J; O'Kelly, J; Uskokovic, MR; Tomoyasu, S; Koeffler, HP
    Novel vitamin D-3 analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D-3, that modulates cell growth, differentiation, apoptosis, cell cycle, and inductionof PTEN in leukemic cells
    BLOOD
    
    J. Hisatake et al., "Novel vitamin D-3 analog, 21-(3-methyl-3-hydroxy-butyl)-19-nor D-3, that modulates cell growth, differentiation, apoptosis, cell cycle, and inductionof PTEN in leukemic cells", BLOOD, 97(8), 2001, pp. 2427-2433
49. Velazhahan, R; Radhajeyalakshmi, R; Thangavelu, R; Muthukrishnan, S
    An antifungal protein purified from pearl millet seeds shows sequence homology to lipid transfer proteins
    BIOLOGIA PLANTARUM
    
    R. Velazhahan et al., "An antifungal protein purified from pearl millet seeds shows sequence homology to lipid transfer proteins", BIOL PLANT, 44(3), 2001, pp. 417-421
50. Koch, E; Klaas, CA; Rungeler, P; Castro, V; Mora, G; Vichnewski, W; Merfort, I
    Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-kappa B
    BIOCHEMICAL PHARMACOLOGY
    
    E. Koch et al., "Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-kappa B", BIOCH PHARM, 62(6), 2001, pp. 795-801
51. Billack, B; Heck, DE; Porterfield, DM; Malchow, RP; Smith, PJS; Gardner, CR; Laskin, DL; Laskin, DJ
    Minimal amidine structure for inhibition of nitric oxide biosynthesis
    BIOCHEMICAL PHARMACOLOGY
    
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52. Pai, TG; Suiko, M; Sakakibara, Y; Liu, MC
    Sulfation of flavonoids and other phenolic dietary compounds by the human cytosolic sulfotransferases
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    
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53. Supuran, CT; Briganti, F; Mincione, G; Scozzafava, A
    Protease inhibitors: Synthesis of L-alanine hydroxamate sulfonylated derivatives as inhibitors of Clostridium histolyticum collagenase
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54. Buchardt, J; Schiodt, CB; Krog-Jensen, C; Delaisse, JM; Foged, NT; Meldal, M
    Solid phase combinatorial library of phosphinic peptides for discovery of matrix metalloproteinase inhibitors
    JOURNAL OF COMBINATORIAL CHEMISTRY
    
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55. Buchardt, J; Meldal, M
    Novel methodology for the solid-phase synthesis of phosphinic peptides
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    
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56. Dal Pozzo, A; Fagnoni, N; Bergonzi, R; Vanini, L; de Castiglione, R; Aglio, C; Colli, S
    Synthesis and anti-aggregatory activity of linear retro-inverso RGD peptides
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57. Fretz, H; Furet, P; Garcia-Echeverria, C; Rahuel, J; Schoepfer, J
    Structure-based design of compounds inhibiting Grb2-SH2 mediated protein-protein interactions in signal transduction pathways
    CURRENT PHARMACEUTICAL DESIGN
    
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58. Vilella, D; Sanchez, M; Platas, G; Salazar, O; Genilloud, O; Royo, I; Cascales, C; Martin, I; Diez, T; Silverman, KC; Lingham, RB; Singh, SB; Jayasuriya, H; Pelaez, F
    Inhibitors of farnesylation of Ras from a microbial natural products screening program
    JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
    
    D. Vilella et al., "Inhibitors of farnesylation of Ras from a microbial natural products screening program", J IND MIC B, 25(6), 2000, pp. 315-327
59. Hogberg, M; Morrison, I
    HIV-1 non-nucleoside reverse transcriptase inhibitors
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60. 
    Compounds for the treatment of oestrogen-dependent illnesses
    EXPERT OPINION ON THERAPEUTIC PATENTS
    
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61. Cooper, DR; Hanson-Painton, O
    Protein kinases: Receptors of external signals
    JOURNAL OF CLINICAL LIGAND ASSAY
    
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62. Pastey, MK; Gower, TL; Spearman, PW; Crowe, JE; Graham, BS
    A RhoA-derived peptide inhibits syncytium formation induced by respiratorysyncytial virus and parainfluenza virus type 3
    NATURE MEDICINE
    
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63. Deadman, J
    Proteinase inhibitors and activators strategic targets for therapeutic intervention - Preface
    JOURNAL OF PEPTIDE SCIENCE
    
    J. Deadman, "Proteinase inhibitors and activators strategic targets for therapeutic intervention - Preface", J PEPT SCI, 6(9), 2000, pp. 421-431
64. D'Acquisto, F; Ialenti, A; Ianaro, A; Di Vaio, R; Carnuccio, R
    Local administration of transcription factor decoy oligonucleotides to nuclear factor-kappa B prevents carrageenin-induced inflammation in rat hind paw
    GENE THERAPY
    
    F. D'Acquisto et al., "Local administration of transcription factor decoy oligonucleotides to nuclear factor-kappa B prevents carrageenin-induced inflammation in rat hind paw", GENE THER, 7(20), 2000, pp. 1731-1737
65. Young, RJ; Beams, RM; Carter, K; Clark, HAR; Coe, DM; Chambers, CL; Davies, PI; Dawson, J; Drysdale, MJ; Franzman, KW; French, C; Hodgson, ST; Hodson, HF; Kleanthous, S; Rider, P; Sanders, D; Sawyer, DA; Scott, KJ; Shearer, BG; Stocker, R; Smith, S; Tackley, MC; Knowles, RG
    Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    R.J. Young et al., "Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine", BIOORG MED, 10(6), 2000, pp. 597-600
66. Egbertson, MS; Bednar, B; Askew, BC; Bednar, RA; Brashear, K; Breslin, MJ; Duggan, ME; Fisher, TE; Halczenko, W; Hutchinson, JH; Ihle, N; Prugh, JD; Wai, JS; Gould, RJ; Hartman, GD
    Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    M.S. Egbertson et al., "Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors", BIOORG MED, 10(17), 2000, pp. 1943-1948
67. Kim, SN; Lee, JY; Kim, HJ; Shin, CG; Park, H; Lee, YS
    Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    S.N. Kim et al., "Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides", BIOORG MED, 10(16), 2000, pp. 1879-1882
68. Dragovich, PS; Zhou, R; Webber, SE; Prins, TJ; Kwok, AK; Okano, K; Fuhrman, SA; Zalman, LS; Maldonado, FC; Brown, EL; Meador, JW; Patick, AK; Ford, CE; Brothers, MA; Binford, SL; Matthews, DA; Ferre, RA; Worland, ST
    Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    
    P.S. Dragovich et al., "Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors", BIOORG MED, 10(1), 2000, pp. 45-48
69. Tachibana, Y; Zhu, XK; Krishnan, P; Lee, KH; Bastow, KF
    Characterization of human lung cancer cells resistant to 4 '-O-demethyl-4 beta-(2 ''-nitro-4 ''-fluoroanilino)-4-desoxypodophyllotoxin, a unique compound in the epipodophyllotoxin antitumor class
    ANTI-CANCER DRUGS
    
    Y. Tachibana et al., "Characterization of human lung cancer cells resistant to 4 '-O-demethyl-4 beta-(2 ''-nitro-4 ''-fluoroanilino)-4-desoxypodophyllotoxin, a unique compound in the epipodophyllotoxin antitumor class", ANTI-CANC D, 11(1), 2000, pp. 19-28
70. Luscher-Mattli, M
    Polyanions - a lost chance in the fight against HIV and other virus diseases?
    ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
    
    M. Luscher-Mattli, "Polyanions - a lost chance in the fight against HIV and other virus diseases?", ANTIVIR CHE, 11(4), 2000, pp. 249-259
71. Campbell, MJ; Gombart, AF; Kwok, SH; Park, S; Koeffler, HP
    The anti-proliferative effects of 1 alpha,25(OH)(2)D-3 on breast and prostate cancer cells are associated with induction of BRCA1 gene expression
    ONCOGENE
    
    M.J. Campbell et al., "The anti-proliferative effects of 1 alpha,25(OH)(2)D-3 on breast and prostate cancer cells are associated with induction of BRCA1 gene expression", ONCOGENE, 19(44), 2000, pp. 5091-5097
72. Wang, W; Borchardt, RT; Wang, B
    Orally active peptidomimetic RGD analogs that are glycoprotein IIb/IIIa antagonists
    CURRENT MEDICINAL CHEMISTRY
    
    W. Wang et al., "Orally active peptidomimetic RGD analogs that are glycoprotein IIb/IIIa antagonists", CURR MED CH, 7(4), 2000, pp. 437-453
73. Lebon, F; Ledecq, M
    Approaches to the design of effective HIV-1 protease inhibitors
    CURRENT MEDICINAL CHEMISTRY
    
    F. Lebon e M. Ledecq, "Approaches to the design of effective HIV-1 protease inhibitors", CURR MED CH, 7(4), 2000, pp. 455-477
74. Supuran, CT; Scozzafava, A
    Protease inhibitors. Part 7 Inhibition of Clostridium histolyticum collagenase with sulfonylated derivatives of L-valine hydroxamate
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    
    C.T. Supuran e A. Scozzafava, "Protease inhibitors. Part 7 Inhibition of Clostridium histolyticum collagenase with sulfonylated derivatives of L-valine hydroxamate", EUR J PH SC, 10(1), 2000, pp. 67-76
75. Kim, HJ; Evers, BM; Litvak, DA; Hellmich, MR; Townsend, CM
    Signaling mechanisms regulating bombesin-mediated AP-1 gene induction in the human gastric cancer SIIA
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    
    H.J. Kim et al., "Signaling mechanisms regulating bombesin-mediated AP-1 gene induction in the human gastric cancer SIIA", AM J P-CELL, 279(2), 2000, pp. C326-C334
76. Ashour, OM; Al Safarjalani, ON; Naguib, FNM; Goudgaon, NM; Schinazi, RF; el Kouni, MH
    Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy
    CANCER CHEMOTHERAPY AND PHARMACOLOGY
    
    O.M. Ashour et al., "Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy", CANC CHEMOT, 45(5), 2000, pp. 351-361
77. Barth, A; Romer, W; Oettel, M
    Influence of subchronic administration of oestrone-3-O-sulphamate on oestrone sulphatase activity in liver, spleen and white blood cells of ovariectomized rats
    ARCHIVES OF TOXICOLOGY
    
    A. Barth et al., "Influence of subchronic administration of oestrone-3-O-sulphamate on oestrone sulphatase activity in liver, spleen and white blood cells of ovariectomized rats", ARCH TOXIC, 74(7), 2000, pp. 366-371
78. Dive, V; Lucet-Levannier, K; Georgiadis, D; Cotton, J; Vassiliou, S; Cuniasse, P; Yiotakis, A
    Phosphinic peptide inhibitors as tools in the study of the function of zinc metallopeptidases
    BIOCHEMICAL SOCIETY TRANSACTIONS
    
    V. Dive et al., "Phosphinic peptide inhibitors as tools in the study of the function of zinc metallopeptidases", BIOCH SOC T, 28, 2000, pp. 455-460
79. Davies, SP; Reddy, H; Caivano, M; Cohen, P
    Specificity and mechanism of action of some commonly used protein kinase inhibitors
    BIOCHEMICAL JOURNAL
    
    S.P. Davies et al., "Specificity and mechanism of action of some commonly used protein kinase inhibitors", BIOCHEM J, 351, 2000, pp. 95-105
80. Chen, SY; Yu, YP; You, JZ; Chen, YZ
    Two new methods for synthesis of 4 beta-amino-4-deoxypodophyllotoxin and 4beta-amino-4 '-demethyl-4-deoxypodophyllotoxin
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
    
    S.Y. Chen et al., "Two new methods for synthesis of 4 beta-amino-4-deoxypodophyllotoxin and 4beta-amino-4 '-demethyl-4-deoxypodophyllotoxin", CHEM J CH U, 21(7), 2000, pp. 1064-1066
81. Teller, S; Eluwa, S; Koller, M; Uecker, A; Beckers, T; Baasner, S; Bohmer, FD; Mahboobi, S
    Pyrrolo[3,4-c]-beta-carboline-diones as a novel class of inhibitors of theplatelet-derived growth factor receptor kinase
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    
    S. Teller et al., "Pyrrolo[3,4-c]-beta-carboline-diones as a novel class of inhibitors of theplatelet-derived growth factor receptor kinase", EUR J MED C, 35(4), 2000, pp. 413-427
82. Scozzafava, A; Supuran, CT
    Protease inhibitors - Part 5. Alkyl/arylsulfonyl- and arylsulfonylureido-/arylureido- glycine hydroxamate inhibitors of Clostridium histolyticum collagenase
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
    
    A. Scozzafava e C.T. Supuran, "Protease inhibitors - Part 5. Alkyl/arylsulfonyl- and arylsulfonylureido-/arylureido- glycine hydroxamate inhibitors of Clostridium histolyticum collagenase", EUR J MED C, 35(3), 2000, pp. 299-307
83. Choi, SH; Cho, JY; Chung, YS; Hong, EK; Han, YB; Kim, SG
    Inhibition of lipopolysaccharide-induced I-kappa B degradation and tumor necrosis factor-alpha expression by acriflavine, an antimicrobial agent
    INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY
    
    S.H. Choi et al., "Inhibition of lipopolysaccharide-induced I-kappa B degradation and tumor necrosis factor-alpha expression by acriflavine, an antimicrobial agent", INT J IMMUN, 22(10), 2000, pp. 775-787
84. Pommier, Y; Marchand, C; Neamati, N
    Retroviral integrase inhibitors year 2000: update and perspectives
    ANTIVIRAL RESEARCH
    
    Y. Pommier et al., "Retroviral integrase inhibitors year 2000: update and perspectives", ANTIVIR RES, 47(3), 2000, pp. 139-148
85. Liu, YJ; Nakagawa, Y; Toya, K; Wang, Y; Saegusa, H; Nakanishi, T; Ohzeki, T
    Effects of spironolactone on systolic blood pressure in experimental diabetic rats
    KIDNEY INTERNATIONAL
    
    Y.J. Liu et al., "Effects of spironolactone on systolic blood pressure in experimental diabetic rats", KIDNEY INT, 57(5), 2000, pp. 2064-2071
86. Shayman, JA; Abe, A
    1-O-acylceramide synthase
    SPHINGOLIPID METABOLISM AND CELL SIGNALING, PT A
    
    J.A. Shayman e A. Abe, "1-O-acylceramide synthase", METH ENZYM, 311, 2000, pp. 105-117
87. Shayman, JA; Lee, L; Abe, A; Shu, LM
    Inhibitors of glucosylceramide synthase
    SPHINGOLIPID METABOLISM AND CELL SIGNALING, PT A
    
    J.A. Shayman et al., "Inhibitors of glucosylceramide synthase", METH ENZYM, 311, 2000, pp. 373-387
88. Wang, ZX; Li, SM; Heide, L
    Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    
    Z.X. Wang et al., "Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489", ANTIM AG CH, 44(11), 2000, pp. 3040-3048
89. Fernandez, JMG; Mellet, CO
    Chemistry and developments of N-thiocarbonyl carbohydrate derivatives: Sugar isothiocyanates, thioamides, thioureas, thiocarbamates, and their conjugates
    ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL 55
    
    J.M.G. Fernandez e C.O. Mellet, "Chemistry and developments of N-thiocarbonyl carbohydrate derivatives: Sugar isothiocyanates, thioamides, thioureas, thiocarbamates, and their conjugates", ADV CARB C, 55, 2000, pp. 35-135
90. De Santi, C; Pietrabissa, A; Spisni, R; Mosca, F; Pacifici, GM
    Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids
    XENOBIOTICA
    
    C. De Santi et al., "Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids", XENOBIOTICA, 30(9), 2000, pp. 857-866
91. Capriati, V; Florio, S; Luisi, R; Russo, V; Salomone, A
    Oxiranyllithium based synthesis of alpha-keto-2-oxazolines
    TETRAHEDRON LETTERS
    
    V. Capriati et al., "Oxiranyllithium based synthesis of alpha-keto-2-oxazolines", TETRAHEDR L, 41(45), 2000, pp. 8835-8838
92. Lee, NE; Williard, PG; Brown, AJ; Campbell, MJ; Koeffler, HP; Peleg, S; Rao, DS; Reddy, GS
    Synthesis and biological activities of the two C(23) epimers of 1 alpha,23,25-trihydroxy-24-oxo-19-nor-vitamin D-3: novel analogs of 1 alpha,23(S),25-trihydroxy-24-oxo-vitamin D-3, a natural metabolite of 1 alpha,25-dihydroxyvitamin D-3
    STEROIDS
    
    N.E. Lee et al., "Synthesis and biological activities of the two C(23) epimers of 1 alpha,23,25-trihydroxy-24-oxo-19-nor-vitamin D-3: novel analogs of 1 alpha,23(S),25-trihydroxy-24-oxo-vitamin D-3, a natural metabolite of 1 alpha,25-dihydroxyvitamin D-3", STEROIDS, 65(5), 2000, pp. 252-265
93. Ludwig-Muller, J; Schubert, B; Rademacher, W; Hilgenberg, W
    Indole-3-butyric acid biosynthesis in maize is enhanced by cyclohexanedione herbicides
    PHYSIOLOGIA PLANTARUM
    
    J. Ludwig-Muller et al., "Indole-3-butyric acid biosynthesis in maize is enhanced by cyclohexanedione herbicides", PHYSL PLANT, 110(4), 2000, pp. 544-550
94. Witvrouw, M; Fikkert, V; Pluymers, W; Matthews, B; Mardel, K; Schols, D; Raff, J; Debyser, Z; De Clercq, E; Holan, G; Pannecouque, C
    Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (Reverse transcriptase/integrase) in the virus replicative cycle
    MOLECULAR PHARMACOLOGY
    
    M. Witvrouw et al., "Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (Reverse transcriptase/integrase) in the virus replicative cycle", MOLEC PHARM, 58(5), 2000, pp. 1100-1108
95. Pluymers, W; Neamati, N; Pannecouque, C; Fikkert, V; Marchand, C; Burke, TR; Pommier, Y; Schols, D; De Clercq, E; Debyser, Z; Witvrouw, M
    Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters
    MOLECULAR PHARMACOLOGY
    
    W. Pluymers et al., "Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters", MOLEC PHARM, 58(3), 2000, pp. 641-648
96. Watanabe, S; Takada, A; Watanabe, T; Ito, H; Kida, H; Kawaoka, Y
    Functional importance of the coiled-coil of the Ebola virus glycoprotein
    JOURNAL OF VIROLOGY
    
    S. Watanabe et al., "Functional importance of the coiled-coil of the Ebola virus glycoprotein", J VIROLOGY, 74(21), 2000, pp. 10194-10201
97. Mathews, JM; Young, TF; Tucker, SP; Mackay, JP
    The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil
    JOURNAL OF VIROLOGY
    
    J.M. Mathews et al., "The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil", J VIROLOGY, 74(13), 2000, pp. 5911-5920
98. Sergel, TA; McGinnes, LW; Morrison, TG
    A single amino acid change in the Newcastle disease virus fusion protein alters the requirement for HN protein in fusion
    JOURNAL OF VIROLOGY
    
    T.A. Sergel et al., "A single amino acid change in the Newcastle disease virus fusion protein alters the requirement for HN protein in fusion", J VIROLOGY, 74(11), 2000, pp. 5101-5107
99. Martin, SF; Follows, BC; Hergenrother, PJ; Franklin, CL
    A novel class of zinc-binding inhibitors for the phosphatidylcholine-preferring phospholipase C from Bacillus cereus
    JOURNAL OF ORGANIC CHEMISTRY
    
    S.F. Martin et al., "A novel class of zinc-binding inhibitors for the phosphatidylcholine-preferring phospholipase C from Bacillus cereus", J ORG CHEM, 65(15), 2000, pp. 4509-4514
100. Giraud, E; Luttmann, C; Lavelle, F; Riou, JF; Mailliet, P; Laoui, A
     Multivariate data analysis using D-optimal designs, partial least squares,and response surface modeling: A directional approach for the analysis of farnesyltransferase inhibitors
     JOURNAL OF MEDICINAL CHEMISTRY
     
     E. Giraud et al., "Multivariate data analysis using D-optimal designs, partial least squares,and response surface modeling: A directional approach for the analysis of farnesyltransferase inhibitors", J MED CHEM, 43(9), 2000, pp. 1807-1816