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DNA recognition by the aberrant retinoic acid receptors implicated in human acute promyelocytic leukemia
CELL GROWTH & DIFFERENTIATION
Histone deacetylase as a therapeutic target
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Translocations of the RAR alpha gene in acute promyelocytic leukemia
ONCOGENE
Transcriptional regulation in acute promyelocytic leukemia
ONCOGENE
Common themes in the pathogenesis of acute myeloid leukemia
ONCOGENE
Avian erythroleukemia: a model for corepressor function in cancer
ONCOGENE
Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias?
ONCOGENE
Transcription therapy for cancer
ONCOGENE
Transcription factors and translocations in lymphoid and myeloid leukemia
LEUKEMIA
Genetic lesions and perturbation of chromatin architecture: A road to celltransformation
JOURNAL OF CELLULAR BIOCHEMISTRY
Identification and characterization of BTBD1, a novel BTB domain containing gene on human chromosome 15q24
GENE
Histone deacetylases and transcriptional therapy with their inhibitors
CANCER CHEMOTHERAPY AND PHARMACOLOGY
Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with its transcription factor partners, including the PML-retinoic acidreceptor alpha oncoprotein found in human acute promyelocytic leukemia
MOLECULAR AND CELLULAR BIOLOGY
Oligomerization of ETO is obligatory for corepressor interaction
MOLECULAR AND CELLULAR BIOLOGY
Cloning and characterization of a novel zinc finger protein (MDZF) that isassociated with monocytic differentiation of acute promyelocytic leukemia cells
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
A new functional domain of Bcl6 family that recruits histone deacetylases
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Future perspectives for acute promyelocytic leukemia therapy
SEMINARS IN HEMATOLOGY
The zinc finger domain of Tzfp binds to the tbs motif located at the upstream flanking region of the Aie1 (aurora-C) kinase gene
JOURNAL OF BIOLOGICAL CHEMISTRY
The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D-3-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D-3 receptor
BLOOD
Human endogenous retrovirus protein cORF supports cell transformation and associates with the promyelocytic leukemia zinc finger protein
ONCOGENE
A novel zinc finger gene is fused to EWS in small round cell tumor
ONCOGENE
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta 2 promoter in breast cancer cells
ONCOGENE
Co-repressors 2000
FASEB JOURNAL
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness
GENES & DEVELOPMENT
BCoR, a novel corepressor involved in BCL-6 repression
GENES & DEVELOPMENT
Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway
GENES & DEVELOPMENT
Isolation of a novel histone deacetylase reveals that class I and class IIdeacetylases promote SMRT-mediated repression
GENES & DEVELOPMENT
New agents for acute myelogenous leukemia
LEUKEMIA
Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins
NUCLEIC ACIDS RESEARCH
Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-Cell proto-oncogene product
MOLECULAR AND CELLULAR BIOLOGY
The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein
MOLECULAR AND CELLULAR BIOLOGY
mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor
MOLECULAR AND CELLULAR BIOLOGY
Sequestration and inhibition of Daxx-mediated transcriptional repression by PML
MOLECULAR AND CELLULAR BIOLOGY
In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions
MOLECULAR AND CELLULAR BIOLOGY
NAC-1 is a brain POZ/BTB protein that can prevent cocaine-induced sensitization in the rat
JOURNAL OF NEUROSCIENCE
The mechanism of action of thyroid hormones
ANNUAL REVIEW OF PHYSIOLOGY
Histone deacetylases, transcriptional control, and cancer
JOURNAL OF CELLULAR PHYSIOLOGY
The N-terminal BTB/POZ domain and C-terminal sequences are essential for Tramtrack69 to specify cell fate in the developing Drosophila eye
GENETICS
Gene expression networks underlying retinoic acid-induced differentiation of acute promyelocytic leukemia cells
BLOOD
AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocptic leukemia zinc finger protein
BLOOD
Leukemia initiated by PMLRAR alpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable
BLOOD
Molecular cloning and characterization of a novel human gene containing ankyrin repeat and double BTB/POZ domain
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Myoneurin, a novel member of the BTB/POZ-zinc finger family highly expressed in human muscle
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Methylation, gene expression and the chromatin connection in cancer (review)
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development
MOLECULAR CELL
Retinoid receptors in health and disease: co-regulators and the chromatin connection
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Nuclear hormone receptors: From molecules to diseases
JOURNAL OF INVESTIGATIVE MEDICINE
The PML nuclear bodies: actors or extras?
CURRENT OPINION IN GENETICS & DEVELOPMENT
Formation of PML/RAR alpha high molecular weight nuclear complexes throughthe PML coiled-coil region is essential for the PML/RAR alpha-mediated retinoic acid response
ONCOGENE
Leukemia translocation protein PLZF inhibits cell growth and expression ofcyclin A
ONCOGENE
Overexpressed BCL6 (LAZ3) oncoprotein triggers apoptosis, delays S phase progression and associates with replication foci
ONCOGENE
Deregulation of NPM and PLZF in a variant t(5;17) case of acute promyelocytic leukemia
ONCOGENE
Leukemia: the sophisticated subversion of hematopoiesis by nuclear receptor oncoproteins
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Neutrophil maturation and the role of retinoic acid
EXPERIMENTAL HEMATOLOGY
The zinc finger-associated SCAN box is a conserved oligomerization domain
MOLECULAR AND CELLULAR BIOLOGY
SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RAR alpha) and oncogenic RAR alpha fusion proteins
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: The case of HIC-1 and gamma FBP-B
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Structure-function studies of the BTB/POZ transcriptional repression domain from the promyelocytic leukemia zinc finger oncoprotein
CANCER RESEARCH
Frequent deletion of hSNF5/INI1, a component of the SWI/SNF complex, in chronic myeloid leukemia
CANCER RESEARCH
The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: Biology and clinical significance
BRITISH JOURNAL OF HAEMATOLOGY
HISTONE DEACETYLASE ASSOCIATED WITH MSIN3A MEDIATES REPRESSION BY THEACUTE PROMYELOCYTIC LEUKEMIA-ASSOCIATED PLZF PROTEIN
Oncogene
THE ACUTE PROMYELOCYTIC LEUKEMIA SPECIFIC PML AND PLZF PROTEINS LOCALIZE TO ADJACENT AND FUNCTIONALLY DISTINCT NUCLEAR-BODIES
Oncogene
ACUTE PROMYELOCYTIC LEUKEMIA WITH T(11-17)(Q23-Q12-21) AND A GOOD INITIAL RESPONSE TO PROLONGED ATRA AND COMBINATION CHEMOTHERAPY
British Journal of Haematology
THE RAR-ALPHA-PLZF CHIMERA ASSOCIATED WITH ACUTE PROMYELOCYTIC LEUKEMIA HAS RETAINED A SEQUENCE-SPECIFIC DNA-BINDING DOMAIN
Oncogene
SEQUENCE-SPECIFIC DNA-BINDING AND TRANSCRIPTIONAL REGULATION BY THE PROMYELOCYTIC LEUKEMIA ZINC-FINGER PROTEIN
The Journal of biological chemistry
ACUTE PROMYELOCYTIC LEUKEMIA - FROM CLINIC TO MOLECULAR-BIOLOGY
Stem cells
DEVELOPMENTAL ANALYSIS OF MURINE PROMYELOCYTE LEUKEMIA ZINC-FINGER (PLZF) GENE-EXPRESSION - IMPLICATIONS FOR THE NEUROMERIC MODEL OF THE FOREBRAIN ORGANIZATION
The Journal of neuroscience
TRANSLOCATION OF THE RAR-ALPHA LOCUS TO THE PML OR PLZF GENE IN ACUTEPROMYELOCYTIC LEUKEMIA
British Journal of Haematology