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La ricerca find articoli where soggetti phrase all words 'PKR' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 244 riferimenti
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    1. Dua, K; Williams, TM; Beretta, L
      Translational control of the proteome: Relevance to cancer

      PROTEOMICS
    2. Horng, T; Barton, GM; Medzhitov, R
      TIRAP: an adapter molecule in the Toll signaling pathway

      NATURE IMMUNOLOGY
    3. Farassati, F; Yang, AD; Lee, PWK
      Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1

      NATURE CELL BIOLOGY
    4. Lever, AML
      Gene therapy for HIV

      SEXUALLY TRANSMITTED INFECTIONS
    5. Iwamura, T; Yoneyama, M; Yamaguchi, K; Suhara, W; Mori, W; Shiota, K; Okabe, Y; Namiki, H; Fujita, T
      Induction of IRF-3/-7 kinase and NF-kappa B in response to double-strandedRNA and virus infection: common and unique pathways

      GENES TO CELLS
    6. Querenghi, F; Yu, Q; Billaud, G; Maertens, G; Trepo, C; Zoulim, F
      Evolution of hepatitis C virus genome in chronically infected patients receiving ribavirin monotherapy

      JOURNAL OF VIRAL HEPATITIS
    7. Tee, AR; Proud, CG
      Staurosporine inhibits phosphorylation of translational regulators linked to mTOR

      CELL DEATH AND DIFFERENTIATION
    8. Marcus, PI; Sekellick, MJ
      Combined sequential treatment with interferon and dsRNA abrogates virus resistance to interferon action

      JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
    9. Dagon, Y; Dovrat, S; Vilchik, S; Hacohen, D; Shlomo, G; Sredni, B; Salzberg, S; Nir, U
      Double-stranded RNA-dependent protein kinase, PKR, down-regulates CDC2/cyclin B1 and induces apoptosis in non-transformed but not in v-mos transformed cells

      ONCOGENE
    10. Regad, T; Chelbi-Alix, MK
      Role and fate of PML nuclear bodies in response to interferon and viral infections

      ONCOGENE
    11. Delhem, N; Sabile, A; Gajardo, R; Podevin, P; Abadie, A; Blaton, MA; Kremsdorf, D; Beretta, L; Brechot, C
      Activation of the interferon-inducible protein kinase PKR by Hepatocellular carcinoma derived-Hepatitis C virus core protein

      ONCOGENE
    12. Gil, J; Rullas, J; Garcia, MA; Alcami, J; Esteban, M
      The catalytic activity of dsRNA-dependent protein kinase, PKR, is requiredfor NF-kappa B activation

      ONCOGENE
    13. Essbauer, S; Bremont, M; Ahne, W
      Comparison of the eIF-2 alpha homologous proteins of seven ranaviruses (Iridoviridae)

      VIRUS GENES
    14. Saunders, LR; Jurecic, V; Barber, GN
      The 90-and 110-kDa human NFAR proteins are translated from two differentially spliced mRNAs encoded on chromosome 19p13

      GENOMICS
    15. Jammi, NV; Beal, PA
      Phosphorylation of the RNA-dependent protein kinase regulates its RNA-binding activity

      NUCLEIC ACIDS RESEARCH
    16. Mori, K; Yoshida, K; Tani, J; Nakagawa, Y; Hoshikawa, S; Ito, S
      Double-stranded RNA-induced interferon regulatory factor-1 gene expressionin FRTL-5 rat thyroid cells

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    17. Gimenez-Barcons, M; Franco, S; Suarez, Y; Forns, X; Ampurdanes, S; Puig-Basagoiti, F; Sanchez-Fueyo, A; Barrera, JM; Llovet, JM; Bruix, J; Sanchez-Tapias, JM; Rodes, J; Saiz, JC
      High amino acid variability within the NS5A of hepatitis C virus (HCV) is associated with hepatocellular carcinoma in patients with HCV-1b-related cirrhosis

      HEPATOLOGY
    18. Moradpour, D; Grabscheid, B; Kammer, AR; Schmidtke, G; Groettrup, M; Blum, HE; Cerny, A
      Expression of hepatitis C virus proteins does not interfere with major histocompatibility complex class I processing and presentation in vitro

      HEPATOLOGY
    19. Peters, GA; Hartmann, R; Qin, J; Sen, GC
      Modular structure of PACT: Distinct domains for binding and activating PKR

      MOLECULAR AND CELLULAR BIOLOGY
    20. Lu, LR; Han, AP; Chen, JJ
      Translation initiation control by heme-regulated eukaryotic initiation factor 2 alpha kinase in erythroid cells under cytoplasmic stresses

      MOLECULAR AND CELLULAR BIOLOGY
    21. Ung, TL; Cao, C; Lu, JM; Ozato, K; Dever, TE
      Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR

      EMBO JOURNAL
    22. Donze, O; Abbas-Terki, T; Picard, D
      The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR

      EMBO JOURNAL
    23. Deb, A; Zamanian-Daryoush, M; Xu, Z; Kadereit, S; Williams, BRG
      Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3

      EMBO JOURNAL
    24. Lo, SY; Lin, HH
      Variations within hepatitis C virus E2 protein and response to interferon treatment

      VIRUS RESEARCH
    25. Puig-Basagoiti, F; Saiz, JC; Forns, X; Ampurdanes, S; Gimenez-Barcons, M; Franco, S; Sanchez-Fueyo, A; Costa, J; Sanchez-Tapias, JM; Rodes, J
      Influence of the genetic heterogeneity of the ISDR and PePHD regions of hepatitis C virus on the response to interferon therapy in chronic hepatitis C

      JOURNAL OF MEDICAL VIROLOGY
    26. Witherell, GW; Beineke, P
      Statistical analysis of combined substitutions in nonstructural 5A region of hepatitis C virus and interferon response

      JOURNAL OF MEDICAL VIROLOGY
    27. Jessner, W; Gschwantler, M; Steindl-Munda, P; Hofer, H; Watkins-Riedel, T; Wrba, F; Mueller, C; Gangi, A; Ferenci, P
      Primary interferon resistance and treatment response in chronic hepatitis C infection: a pilot study

      LANCET
    28. Sen, GC
      Viruses and interferons

      ANNUAL REVIEW OF MICROBIOLOGY
    29. Diamond, MS; Harris, E
      Interferon inhibits dengue virus infection by preventing translation of viral RNA through a PKR-independent mechanism

      VIROLOGY
    30. Liu, Y; Wolff, KC; Jacobs, BL; Samuel, CE
      Vaccinia virus E3L interferon resistance protein inhibits the interferon-induced adenosine deaminase A-to-I editing activity

      VIROLOGY
    31. Sarrazin, C; Bruckner, M; Herrmann, E; Ruster, B; Bruch, K; Roth, WK; Zeuzem, S
      Quasispecies heterogeneity of the carboxy-terminal part of the E2 gene including the PePHD and sensitivity of hepatitis C virus 1b isolates to antiviral therapy

      VIROLOGY
    32. Oh, S; Belz, GT; Eichelberger, MC
      Viral neuraminidase treatment of dendritic cells enhances antigen-specificCD8(+) T cell proliferation, but does not account for the CD4(+) T cell independence of the CD8(+) T cell response during influenza virus infection

      VIROLOGY
    33. Tan, SL; Katze, MG
      How hepatitis C virus counteracts the interferon response: The jury is still out on NS5A

      VIROLOGY
    34. Alexopoulou, L; Holt, AC; Medzhitov, R; Flavell, RA
      Recognition of double-stranded RNA and activation of NF-kappa B by Toll-like receptor 3

      NATURE
    35. Cheng, GF; Gross, M; Brett, ME; He, B
      AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2 alpha

      JOURNAL OF VIROLOGY
    36. Balachandran, S; Porosnicu, M; Barber, GN
      Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or Myc function and involves the inductionof apoptosis

      JOURNAL OF VIROLOGY
    37. Burysek, L; Pitha, PM
      Latently expressed human herpesvirus 8-encoded interferon regulatory factor 2 inhibits double-stranded RNA-activated protein kinase

      JOURNAL OF VIROLOGY
    38. Taylor, DR; Tian, B; Romano, PR; Hinnebusch, AG; Lai, MMC; Mathews, MB
      Hepatitis C virus envelope protein E2 does not inhibit PKR by simple competition with autophosphorylation sites in the RNA-binding domain

      JOURNAL OF VIROLOGY
    39. Majumder, M; Ghosh, AK; Steele, R; Ray, R; Ray, RB
      Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner

      JOURNAL OF VIROLOGY
    40. Brandt, TA; Jacobs, BL
      Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model

      JOURNAL OF VIROLOGY
    41. Paludan, SR
      Requirements for the induction of interleukin-6 by herpes simplex virus-infected leukocytes

      JOURNAL OF VIROLOGY
    42. Hummer, BT; Li, XL; Hassel, BA
      Role for p53 in gene induction by double-stranded RNA

      JOURNAL OF VIROLOGY
    43. Hahn, H; Palmenberg, AC
      Deletion mapping of the encephalomyocarditis virus primary cleavage site

      JOURNAL OF VIROLOGY
    44. He, YP; Tan, SL; Tareen, SU; Vijaysri, S; Langland, JO; Jacobs, BL; Katze, MG
      Regulation of mRNA translation and cellular signaling by hepatitis C virusnonstructural protein NS5A

      JOURNAL OF VIROLOGY
    45. Schweizer, M; Peterhans, E
      Noncytopathic bovine viral diarrhea virus inhibits double-stranded RNA-induced apoptosis and interferon synthesis

      JOURNAL OF VIROLOGY
    46. Cristillo, AD; Mortimer, JR; Barrette, IH; Lillicrap, TP; Forsdyke, DR
      Double-stranded RNA as a not-self alarm signal: to evade, most viruses purine-load their RNAs, but some (HTLV-1, Epstein-Barr) pyrimidine-load

      JOURNAL OF THEORETICAL BIOLOGY
    47. Kumar, R; Azam, S; Sullivan, JM; Owen, C; Cavener, DR; Zhang, PC; Ron, D; Harding, HP; Chen, JJ; Han, AP; White, BC; Krause, GS; DeGracia, DJ
      Brain ischemia and reperfusion activates the eukaryotic initiation factor 2 alpha kinase, PERK

      JOURNAL OF NEUROCHEMISTRY
    48. Gil, J; Rullas, J; Alcami, J; Esteban, M
      MC159L protein from the poxvirus molluscum contagiosum virus inhibits NF-kappa B activation and apoptosis induced by PKR

      JOURNAL OF GENERAL VIROLOGY
    49. Saelens, X; Kalai, M; Vandenabeele, P
      Translation inhibition in apoptosis - Caspase-dependent PKR activation andeIF2-alpha phosphorylation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    50. Daher, A; Longuet, M; Dorin, D; Bois, F; Segeral, E; Bannwarth, S; Battisti, PL; Purcell, DF; Benarous, R; Vaquero, C; Meurs, EF; Gatignol, A
      Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression

      JOURNAL OF BIOLOGICAL CHEMISTRY
    51. Parker, LM; Fierro-Monti, I; Mathews, MB
      Nuclear factor 90 is a substrate and regulator of the eukaryotic initiation factor 2 kinase double-stranded RNA-activated protein kinase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    52. Geiss, G; Jin, G; Guo, JJ; Bumgarner, R; Katze, MG; Sen, GC
      A comprehensive view of regulation of gene expression by double-stranded RNA-mediated cell signaling

      JOURNAL OF BIOLOGICAL CHEMISTRY
    53. LaMonica, R; Kocer, SS; Nazarova, J; Dowling, W; Geimonen, E; Shaw, RD; Mackow, ER
      VP4 differentially regulates TRAF2 signaling, disengaging JNK activation while directing NF-kappa B to effect rotavirus-specific cellular responses

      JOURNAL OF BIOLOGICAL CHEMISTRY
    54. Li, SY; Koromilas, AE
      Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR

      JOURNAL OF BIOLOGICAL CHEMISTRY
    55. Ruvolo, PP; Gao, FQ; Blalock, WL; Deng, XM; May, WS
      Ceramide regulates protein synthesis by a novel mechanism involving the cellular PKR activator RAX

      JOURNAL OF BIOLOGICAL CHEMISTRY
    56. Heitmeier, MR; Arnush, M; Scarim, AL; Corbett, JA
      Pancreatic beta-cell damage mediated by beta-cell production of interleukin-1 - A novel mechanism for virus-induced diabetes

      JOURNAL OF BIOLOGICAL CHEMISTRY
    57. Robert, V; Prud'homme, N; Kim, A; Bucheton, A; Pelisson, A
      Characterization of the flamenco region of the Drosophila melanogaster genome

      GENETICS
    58. Conrad, C; Evguenieva-Hackenberg, E; Klug, G
      Both N-terminal catalytic and C-terminal RNA binding domain contribute to substrate specificity and cleavage site selection of RNase III

      FEBS LETTERS
    59. Vattem, KM; Staschke, KA; Zhu, SH; Wek, RC
      Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2 alpha (elF2 alpha)

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    60. Vattem, KM; Staschke, KA; Wek, RC
      Mechanism of activation of the double-stranded-RNA-dependent protein kinase PKR - Role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (elF2)

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    61. Blair, LA; Heitmeier, MR; Scarim, AL; Maggi, LB; Corbett, JA
      Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets

      DIABETES
    62. Rabinovici, R; Kabir, K; Chen, MH; Su, YJ; Zhang, DX; Luo, XX; Yang, JH
      ADAR1 is involved in the development of microvascular lung injury

      CIRCULATION RESEARCH
    63. Bergmann, M; Romirer, I; Sachet, M; Fleischhacker, R; Garcia-Sastre, A; Palese, P; Wolff, K; Pehamberger, H; Jakesz, R; Muster, T
      A genetically engineered influenza A virus with ras-dependent oncolytic properties

      CANCER RESEARCH
    64. Pang, QS; Keeble, W; Diaz, J; Christianson, TA; Fagerlie, S; Rathbun, K; Faulkner, GR; O'Dwyer, M; Bagby, GC
      Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA

      BLOOD
    65. Spanggord, RJ; Beal, PA
      Selective binding by the RNA binding domain of PKR revealed by affinity cleavage

      BIOCHEMISTRY
    66. Matsui, T; Tanihara, K; Date, T
      Expression of unphosphorylated form of human double-stranded RNA-activatedprotein kinase in Escherichia coli

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    67. Iwamura, T; Yoneyama, M; Koizumi, N; Okabe, Y; Namiki, H; Samuel, CE; Fujita, T
      PACT, a double-stranded RNA binding protein acts as a positive regulator for type 1 interferon gene induced by Newcastle disease virus

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    68. Kimball, SR; Clemens, MJ; Tilleray, VJ; Wek, RC; Horetsky, RL; Jefferson, LS
      The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    69. Scarim, AL; Arnush, M; Blair, LA; Concepcion, J; Heitmeier, MR; Scheuner, D; Kaufman, RJ; Ryerse, J; Buller, RM; Corbett, JA
      Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma - dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis

      AMERICAN JOURNAL OF PATHOLOGY
    70. Balachandran, S; Barber, GN
      Vesicular stomatitis virus (VSV) therapy of tumors

      IUBMB LIFE
    71. Melville, MW; Katze, MG; Tan, SL
      p58(IPK), novel cochaperone containing tetratricopeptide repeats and a J-domain with oncogenic potential

      CELLULAR AND MOLECULAR LIFE SCIENCES
    72. Thompson, SR; Sarnow, P
      Regulation of host cell translation by viruses and effects on cell function

      CURRENT OPINION IN MICROBIOLOGY
    73. Gil, J; Esteban, M
      Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action

      APOPTOSIS
    74. Voutsadakis, IA
      Interferon-alpha and the pathogenesis of myeloproliferative disorders

      MEDICAL ONCOLOGY
    75. Tian, B; White, RJ; Xia, TB; Welle, S; Turner, DH; Mathews, MB; Thornton, CA
      Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR

      RNA-A PUBLICATION OF THE RNA SOCIETY
    76. Smith, ER; Chiocca, EA
      Oncolytic viruses as novel anticancer agents: turning one scourge against another

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    77. Taylor, DR; Shi, ST; Lai, MMC
      Hepatitis C virus and interferon resistance

      MICROBES AND INFECTION
    78. Perea, SE; Massimi, P; Banks, L
      Human papillomavirus type 16 E7 impairs the activation of the interferon regulatory factor-1

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    79. Sen, GC
      Novel functions of interferon-induced proteins

      SEMINARS IN CANCER BIOLOGY
    80. Brizard, F; Luo, M; DesGroseillers, L
      Genomic organization of the human and mouse stau genes

      DNA AND CELL BIOLOGY
    81. Lu, C; Fedoroff, N
      A mutation in the arabidopsis HYL1 gene encoding a dsRNA binding protein affects responses to abscisic acid, auxin, and cytokinin

      PLANT CELL
    82. Duarte, M; Graham, K; Daher, A; Battisti, PL; Bannwarth, S; Segeral, E; Jeang, KT; Gatignol, A
      Characterization of TRBP1 and TRBP2 - Stable stem-loop structure at the 5 ' end of TRBP2 mRNA resembles HIV-1 TAR and is not found in its processed pseudogene

      JOURNAL OF BIOMEDICAL SCIENCE
    83. Bae, SH; Park, YM; Yoo, DG; Choi, JY; Byun, BH; Yang, JM; Lee, CD; Cha, SB; Park, DH; Kim, BS
      Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a predictive factor for response to interferon-alpha therapy and development of hepatocellular carcinoma

      JOURNAL OF KOREAN MEDICAL SCIENCE
    84. Fierro-Monti, I; Mathews, MB
      Proteins binding to duplexed RNA: one motif, multiple functions

      TRENDS IN BIOCHEMICAL SCIENCES
    85. Gil, J; Esteban, M
      The interferon-induced protein kinase (PKR), triggers apoptosis through FADD-mediated activation of caspase 8 in a manner independent of Fas and TNF-alpha receptors

      ONCOGENE
    86. Kim, SH; Forman, AP; Mathews, MB; Gunnery, S
      Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR

      ONCOGENE
    87. Gil, J; Alcami, J; Esteban, M
      Activation of NF-kappa B by the dsRNA-dependent protein kinase, PKR involves the I kappa B kinase complex

      ONCOGENE
    88. Taylor, DR
      Hepatitis C virus: evasion of the interferon-induced antiviral response

      JOURNAL OF MOLECULAR MEDICINE-JMM
    89. Zhou, Y; Wang, S; Gobl, A; Oberg, K
      The interferon-alpha regulation of interferon regulatory factor 1 (IRF-1) and IRF-2 has therapeutic implications in carcinoid tumors

      ANNALS OF ONCOLOGY
    90. Hariya, Y; Yokosawa, N; Yonekura, N; Kohama, G; Fujii, N
      Mumps virus can suppress the effective augmentation of HPC-induced apoptosis by IFN-gamma through disruption of IFN signaling in U937 cells

      MICROBIOLOGY AND IMMUNOLOGY
    91. Duchange, N; Pidoux, J; Camus, E; Sauvaget, D
      Alternative splicing in the human interleukin enhancer binding factor 3 (ILF3) gene

      GENE
    92. Tanaka, H; Samuel, CE
      Mouse interferon-inducible RNA-dependent protein kinase Pkr gene: cloning and sequence of the 5 '-flanking region and functional identification of the minimal inducible promoter

      GENE
    93. Spanggord, RJ; Beal, PA
      Site-specific modification and RNA crosslinking of the RNA-binding domain of PKR

      NUCLEIC ACIDS RESEARCH
    94. Coolidge, CJ; Patton, JG
      A new double-stranded RNA-binding protein that interacts with PKR

      NUCLEIC ACIDS RESEARCH
    95. Vuyisich, M; Beal, PA
      Regulation of the RNA-dependent protein kinase by triple helix formation

      NUCLEIC ACIDS RESEARCH
    96. Rehermann, B
      Interaction between the hepatitis C virus and the immune system

      SEMINARS IN LIVER DISEASE
    97. Berg, T; Marques, AM; Hohne, M; Wiedenmann, B; Hopf, U; Schreier, E
      Mutations in the E2-PePHD and NS5A region of hepatitis C virus type 1 and the dynamics of hepatitis C viremia decline during interferon alfa treatment

      HEPATOLOGY
    98. Yu, SH; Nagayama, K; Enomoto, N; Izumi, N; Marumo, F; Sato, C
      Intrahepatic mRNA expression of interferon-inducible antiviral genes in liver diseases: dsRNA-dependent protein kinase overexpression and RNase L inhibitor suppression in chronic hepatitis C

      HEPATOLOGY
    99. Sarrazin, C; Kornetsky, I; Ruster, B; Lee, JH; Kronenberger, B; Bruch, K; Roth, WK; Zeuzem, S
      Mutations within the E2 and NS5A protein in patients infected with hepatitis C virus type 3a and correlation with treatment response

      HEPATOLOGY
    100. Ramos, A; Grunert, S; Adams, J; Micklem, DR; Proctor, MR; Freund, S; Bycroft, M; St Johnston, D; Varani, G
      RNA recognition by a Staufen double-stranded RNA-binding domain

      EMBO JOURNAL


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Documento generato il 01/06/20 alle ore 00:52:36