Si mostrano 100 riferimenti a partire da 1 |
Per ulteriori informazioni selezionare i riferimenti di interesse.
E5 protein of human papillomavirus type 16 protects human foreskin keratinocytes from UVB-irradiation-induced apoptosis
JOURNAL OF VIROLOGY
Biosynthesis and processing of cathepsin K in cultured human osteoclasts
BONE
Time course of the MAPK and PI3-kinase response within 24 h of skeletal muscle overload
JOURNAL OF APPLIED PHYSIOLOGY
Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles
JOURNAL OF APPLIED PHYSIOLOGY
Signal transduction in smooth muscle - Invited review: The circle of life:cell cycle regulation in airway smooth muscle
JOURNAL OF APPLIED PHYSIOLOGY
Differential effects of exercise on insulin-signaling gene expression in human skeletal muscle
JOURNAL OF APPLIED PHYSIOLOGY
Exercise training increases ERK2 activity in skeletal muscle of obese Zucker rats
JOURNAL OF APPLIED PHYSIOLOGY
Insulin-sensitive phospholipid signaling systems and glucose transport. Update II
EXPERIMENTAL BIOLOGY AND MEDICINE
Insulin resistance: Cellular and clinical concepts
EXPERIMENTAL BIOLOGY AND MEDICINE
Proteolysis-independent regulation of P13K by Cbl-b-mediated ubiquitination in T cells
NATURE IMMUNOLOGY
A point mutation in CD28 distinguishes proliferative signals from survivalsignals
NATURE IMMUNOLOGY
On guard - activating NK cell receptors
NATURE IMMUNOLOGY
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not T(H)2 cytokines
NATURE IMMUNOLOGY
Downregulation of Akt1 inhibits anchorage-independent cell growth and induces apoptosis in cancer cells
NEOPLASIA
Differential effect of PKC isoform on insulin- and phorbol ester-stimulated glucose uptake mechanism in rat adipocytes
IUBMB LIFE
Prostaglandylinositol cyclic phosphate (cPIP): a novel second messenger ofinsulin action. Comparative analysis of two kinds of 'insulin mediators'
DIABETES-METABOLISM RESEARCH AND REVIEWS
Phosphoinositide 3-kinases in the gut: a link between inflammation and cancer?
TRENDS IN MOLECULAR MEDICINE
Tie receptors: New modulators of angiogenic and lymphangiogenic responses
NATURE REVIEWS MOLECULAR CELL BIOLOGY
SNX3 regulates endosomal function through its PX-domain-mediated interaction with Ptdlns(3)P
NATURE CELL BIOLOGY
The PX domains of p47phox and p40phox bind to lipid products of Pl(3)K
NATURE CELL BIOLOGY
Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain
NATURE CELL BIOLOGY
Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?
BREAST CANCER RESEARCH
Effect of vanadate on glycogen synthesis in dexamethasone-treated 3T3 adipocytes: evidence for a novel insulin sensitizing action
DIABETES OBESITY & METABOLISM
The Akt/PKB pathway is constitutively activated in Theileria-transformed leucocytes, but does not directly control constitutive NF-kappa B activation
CELLULAR MICROBIOLOGY
Insulin resistance induced by loop diuretics and hyperosmolarity in perfused rat liver
BIOLOGICAL CHEMISTRY
GLUT4 - At the cross roads between membrane trafficking and signal transduction
TRAFFIC
Pharmacology of phosphoinositides, regulators of multiple cellular functions
CURRENT PHARMACEUTICAL DESIGN
IGF-I receptor signalling in transformation and differentiation
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
Early decrease of survival signal-related proteins in spinal motor neuronsof presymptomatic transgenic mice with a mutant SOD1 gene
APOPTOSIS
Anti-apoptotic action of macrophage stimulating protein (MSP)
APOPTOSIS
Role of apoptosis of renal tubular cells in acute renal failure: Therapeutic implications
APOPTOSIS
Stimulation of tetrahydrobiopterin synthesis induced by insulin: possible involvement of phosphatidylinositol 3-kinase
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Regulation of insulin-stimulated tyrosine phosphorylation of Shc and Shc/Grb2 association in liver, muscle, and adipose tissue of epinephrine- and streptozotocin-treated rats
ENDOCRINE
Phosphoinositide 3-kinase inhibition in cancer treatment
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Prospects for phosphoinositide 3-kinase inhibition as a cancer treatment
ENDOCRINE-RELATED CANCER
Rac1 regulates heat shock responses by reorganization of vimentin filaments: Identification using MALDI-TOF MS
CELL DEATH AND DIFFERENTIATION
Role of IL-10 in allergen-specific immunotherapy and normal response to allergens
MICROBES AND INFECTION
Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons
NATURE NEUROSCIENCE
PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation
NATURE NEUROSCIENCE
Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle
MOLECULAR CELL
The class II phosphoinositide 3-kinase C2 alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking
MOLECULAR CELL
Dehydroepiandrosterone (DHEA) stimulates glucose uptake in rat adipocytes:activation of phospholipase D
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Insulin-like growth factor-I augments prolactin and inhibits growth hormone release through distinct as well as overlapping cellular signaling pathways
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
In vitro hormone induction of final oocyte maturation in striped bass (Morone saxatilis) follicles is inhibited by blockers of phosphatidylinositol 3-kinase activity
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress
PHYSIOLOGICAL GENOMICS
Skeletal muscle and insulin sensitivity: Pathophysiological alterations
FRONTIERS IN BIOSCIENCE
Hypoosmotic stress stimulates growth in HepG2 cells via protein kinase B-dependent activation of activator protein-1
JOURNAL OF GASTROINTESTINAL SURGERY
Cellular function of phosphoinositide 3-kinases: Implications for development, immunity, homeostasis, and cancer
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
Rapamycin blocks IL-2-driven T cell cycle progression while preserving T cell survival
BLOOD CELLS MOLECULES AND DISEASES
Cell cycle protein expression in vascular smooth muscle cells in vitro andin vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Exercise training eliminates age-related differences in skeletal muscle insulin receptor and IRS-1 abundance in rats
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
Disruption of Akt kinase activation is important for immunosuppression induced by measles virus
NATURE MEDICINE
HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals
NATURE MEDICINE
Inhibition of insulin-like growth factor signaling pathways in mammary gland by pure antiestrogen ICI 182,780
CLINICAL CANCER RESEARCH
Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression
CLINICAL CANCER RESEARCH
Antiapoptotic activity is dispensable for insulin-like growth factor I receptor-mediated clonogenic radioresistance after gamma-irradiation
CLINICAL CANCER RESEARCH
Wortmannin inhibits PKB/Akt phosphorylation and promotes gemeitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice
CLINICAL CANCER RESEARCH
Wortmannin inhibits platelet aggregation produced by interaction of gamma-aminobutyric acid and the calcium ionophore, A23187
RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY
The small GTPase Rac suppresses apoptosis caused by serum deprivation in fibroblasts
MOLECULAR MEDICINE
Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK
MOLECULAR MEDICINE
Regulation of laminin 1-induced pancreatic beta-cell differentiation by alpha(6) integrin and alpha-dystroglycan
MOLECULAR MEDICINE
Molecular competition for NKG2D: H60 and RAE1 compete unequally for NKG2D with dominance of H60
IMMUNITY
Active site labeling of the gentamicin resistance enzyme AAQ6 ')-APH(2 '')by the lipid kinase inhibitor wortmannin
CHEMISTRY & BIOLOGY
Effect of wortmannin on human eosinophil responses in vitro and on bronchial inflammation and airway hyperresponsiveness in guinea pigs in vivo
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Activation of endothelial cell mitogen activated protein kinase ERK1/2 by extracellular HIV-1 Tat protein
ENDOTHELIUM-NEW YORK
Sequential activities of phosphoinositide 3-kinase, PKB/Akt, and Rab7 during macropinosome formation in Dictyostelium
MOLECULAR BIOLOGY OF THE CELL
Src family kinases are required for prolactin induction of cell proliferation
MOLECULAR BIOLOGY OF THE CELL
Tumor necrosis factor-alpha induces stress fiber formation through ceramide production: Role of sphingosine kinase
MOLECULAR BIOLOGY OF THE CELL
Dual role of H-Ras in regulation of lymphocyte function antigen-1 activityby stromal cell-derived factor-1 alpha: Implications for leukocyte transmigration
MOLECULAR BIOLOGY OF THE CELL
Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells
MOLECULAR BIOLOGY OF THE CELL
Ethnicity and type 2 diabetes - Focus on Asian Indians
JOURNAL OF DIABETES AND ITS COMPLICATIONS
ATM as a target for novel radiosensitizers
SEMINARS IN RADIATION ONCOLOGY
Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance
TRENDS IN CARDIOVASCULAR MEDICINE
Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals
CELL GROWTH & DIFFERENTIATION
PTEN/MMAC1 overexpression decreases insulin-like growth factor-I-mediated protection from apoptosis in neuroblastoma cells
CELL GROWTH & DIFFERENTIATION
Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells
CELL GROWTH & DIFFERENTIATION
Requirement of tyrosine-phosphorylated Vav for morphological differentiation of all-trans-retinoic acid-treated HL-60 cells
CELL GROWTH & DIFFERENTIATION
Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells
CELL GROWTH & DIFFERENTIATION
Regulation of extracellular signal-regulated kinase activity by p120 RasGAP does not involve its pleckstrin homology or calcium-dependent lipid binding domains but does require these domains to regulate cell proliferation
CELL GROWTH & DIFFERENTIATION
The FLT3 tyrosine kinase receptor inhibits neural stem/progenitor cell proliferation and collaborates with NGF to promote neuronal survival
MOLECULAR AND CELLULAR NEUROSCIENCE
Role of STAT3 and Pl 3-Kinase/Akt in mediating the survival actions of cytokines on sensory neurons
MOLECULAR AND CELLULAR NEUROSCIENCE
Analysis of the NF-kappa B and Pl 3-kinase/Akt survival pathways in nerve growth factor-dependent neurons
MOLECULAR AND CELLULAR NEUROSCIENCE
Neuregulin signaling through a PI3K/Akt/Bad pathway in Schwann cell survival
MOLECULAR AND CELLULAR NEUROSCIENCE
Akt1/PKB alpha protects PC12 cells against the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium and reduces the levels of oxygen-free radicals
MOLECULAR AND CELLULAR NEUROSCIENCE
Signalling events regulating lymphoid growth and survival
SEMINARS IN CANCER BIOLOGY
Scatter factors and invasive growth
SEMINARS IN CANCER BIOLOGY
Activation of class IA PI3K stimulates DNA synthesis in human airway smooth muscle cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
ERK activation and mitogenesis in human airway smooth muscle cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Reactive oxygen species stimulate VEGF production from C2C12 skeletal myotubes through a PI3K/Akt pathway
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Selective protection of mitogenically stimulated human lymphocytes but notleukemic cells from cytosine arabinoside-induced apoptosis by LY294002, a phosphoinositol-3 kinase inhibitor
INTERNATIONAL JOURNAL OF ONCOLOGY
Involvement of PI3K in PKC epsilon-mediated oncogenic signal in rat colonic epithelial cells
INTERNATIONAL JOURNAL OF ONCOLOGY
Trans-resveratrol, a grapevine-derived polyphenol, blocks hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells
INTERNATIONAL JOURNAL OF ONCOLOGY
Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGFreceptors in human skin in vivo
INTERNATIONAL JOURNAL OF ONCOLOGY
Increased activity and nuclear localisation of inositol lipid signal transduction enzymes in rat hepatoma cells
INTERNATIONAL JOURNAL OF ONCOLOGY
Extracellular signal-regulated kinase and the small GTP-binding protein p21Rac1 are involved in the regulation of gene transcription by angiotensin II
EXPERIMENTAL NEPHROLOGY
Tyrosine phosphorylation-dependent yeast two-hybrid system for the identification of the SH2 domain-binding proteins
MOLECULES AND CELLS
Phosphorylated map kinase (ERK1, ERK2) expression is associated with earlytau deposition in neurones and glial cells, but not with increased nuclearDNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
BRAIN PATHOLOGY
Insulin-like growth factor-I in muscle metabolism and myotherapies
NEUROBIOLOGY OF DISEASE
Alterations of Akt1 (PKB alpha) and p70(S6K) in transient focal ischemia
NEUROBIOLOGY OF DISEASE
Molecular machinery involved in the insulin-regulated fusion of GLUT4-containing vesicles with the plasma membrane
MOLECULAR MEMBRANE BIOLOGY