Si mostrano 100 riferimenti a partire da 1 |
Per ulteriori informazioni selezionare i riferimenti di interesse.
Evolution of bone marrow transplantation - the original immunotherapy
TRENDS IN IMMUNOLOGY
Transgenic interleukin 2 secreted by CML dendritic cells stimulates autologous T(H)1 T cells
CYTOTHERAPY
Small molecule: large hopes
INTERNAL MEDICINE JOURNAL
Mechanisms of resistance imatinib (ST1571) in preclinical models and in leukemia patients
DRUG RESISTANCE UPDATES
13cis-and all-trans retinoic acid have antiproliferative effects on CML cells and render IFN alpha antiproliferative potency after combined treatmentin vitro
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
Model mice for BCR/ABL-positive leukemias
BLOOD CELLS MOLECULES AND DISEASES
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase
NATURE MEDICINE
Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: The first fusion gene involving BCR but not ABL
GENES CHROMOSOMES & CANCER
Nonrandom distribution of interspersed repeat elements in the BCR and ABLIgenes and its relation to breakpoint cluster regions
GENES CHROMOSOMES & CANCER
BCR-ABL fusion peptides and cytotoxic T cells in chronic myeloid leukaemia
LEUKEMIA & LYMPHOMA
Interferon-alpha combined with cytarabine in chronic myelogenous leukemia - Clinical benefits
LEUKEMIA & LYMPHOMA
Aberrant BCR-ABL transcript with intronic insertion in a patient with Philadelphia chromosome-positive chronic myeloid leukemia: Implications for disease progression
LEUKEMIA & LYMPHOMA
Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation
ONCOGENE
BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model
ONCOGENE
Philadelphia chromosome-positive acute lymphoblastic leukemia in Taiwan
ANNALS OF HEMATOLOGY
A variant form of myelodysplastic syndrome with Ph- minor-BCR/ABL transcript
INTERNATIONAL JOURNAL OF HEMATOLOGY
Molecular biology of chronic myeloid leukemia
INTERNATIONAL JOURNAL OF HEMATOLOGY
From xeroderma pigmentosum to the biological clock contributions of Dirk Bootsma to human genetics
MUTATION RESEARCH-DNA REPAIR
The biology and treatment of chronic myelogenous leukemia - The Brunstein/McGlave article reviewed
ONCOLOGY-NEW YORK
Role of the tyrosine phosphatase SHP-1 in K562 cell differentiation
LEUKEMIA
Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and gamma-irradiation
LEUKEMIA
Clinicopathologic characteristics of leukemia in Japanese children and young adults
LEUKEMIA
Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy
LEUKEMIA
International childhood Acute Lymphoblastic Leukemia workshop: Sausalito, CA, 30 November-1 December 2000
LEUKEMIA
Suppressed apoptosis of pre-B cells in bone marrow of pre-leukemic p190(bcr/abl) transgenic mice
LEUKEMIA
ABL1 methylation in Ph-positive ALL is exclusively associated with the P210 form of BCR-ABL
LEUKEMIA
Effect of a selective Abl tyrosine kinase inhibitor, STI571, on in vitro growth of BCR-ABL-positive acute lymphoblastic leukemia cells
LEUKEMIA
Adult precursor B-ALL with BCR/ABL gene rearrangements displays a unique immunophenotype based on the pattern of CD10, CD34, CD13 and CD38 expression
LEUKEMIA
Growth advantage of chronic myeloid leukemia CFU-GM in vitro: survival to growth factor deprivation, possibly related to autocrine stimulation, is a more common feature than hypersensitivity to GM-CSF/IL3 and is efficiently counteracted by retinoids +/- alpha-interferon
LEUKEMIA
The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome
LEUKEMIA
Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia
LEUKEMIA
BCR rearrangement-negative chronic myelogenous leukemia revisited
JOURNAL OF CLINICAL ONCOLOGY
Cepharanthine activates caspases and induces apoptosis in Jurkat and K562 human leukemia cell lines
JOURNAL OF CELLULAR BIOCHEMISTRY
Quantification of bcr/abl mRNA expression by a rapid real time reverse transcription-polymerase chain reaction assay in patients with chronic myeloidleukemia
HAEMATOLOGICA
Multiplex-polymerase chain reaction assay for the detection of prognostically significant translocations in acute lymphoblastic leukemia
HAEMATOLOGICA
Successful unrelated cord blood transplantation in Philadelphia chromosomepositive acute lymphoblastic leukemia during pulmonary aspergillosis treated by anti-fungal therapy, granulocyte colony-stimulating factor-mobilized granulocytes and surgical resection: Case report
JAPANESE JOURNAL OF CLINICAL ONCOLOGY
Human stem cell model to study signal transduction and molecular regulation mechanisms in CML
CHINESE MEDICAL JOURNAL
Engineering dendritic cell grafts for clinical trials in cellular immunotherapy of cancer: Example of chronic myelogenous leukemia
CROATIAN MEDICAL JOURNAL
CD80 (B7-1) expression on human acute myeloid leukaemic cells cultured with GM-CSF, IL-3 and IL-6
CANCER IMMUNOLOGY IMMUNOTHERAPY
Dendritic-cell-peptide immunization provides immunoprotection against bcr-abl-positive leukemia in mice
CANCER IMMUNOLOGY IMMUNOTHERAPY
Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity
NUCLEIC ACIDS RESEARCH
Bcr-Abl inhibition as a modality of CML therapeutics
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
A comparison of normal and leukemic stem cell biology in chronic myeloid leukemia
HEMATOLOGICAL ONCOLOGY
The NH2-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-Abl
MOLECULAR AND CELLULAR BIOLOGY
Tyrosine kinase inhibitors in the treatment of chronic myeloid leukaemia: so far so good?
BLOOD REVIEWS
Autologous reconstitution combined with durable leukemic remission after allogeneic BMT for CML: absence of persistence of a donor-derived T cell effector population
BONE MARROW TRANSPLANTATION
Chronic myelogenous leukemic and tyrosine kinase inhibitors.
REVUE DE MEDECINE INTERNE
Bone marrow engraftment: histopathology of hematopoietic reconstitution following allogeneic transplantation in CML patients
HISTOLOGY AND HISTOPATHOLOGY
Two step mechanism for formation of complex 9;22 chromosome translocation in chronic myelocytic leukemia detected by fluorescence in situ hybridization
EXPERIMENTAL ONCOLOGY
Deletion of BCR region 3 ' in chronic myelogenous leukemia
CANCER GENETICS AND CYTOGENETICS
Problems with interphase fluorescence in situ hybridization in detecting BCR/ABL-positive cells in some patients using a novel technique with extra signals
CANCER GENETICS AND CYTOGENETICS
Possible prediction of myeloid and lymphoid crises in chronic myelocytic leukemia at onset by determining the methylation status of the major breakpoint cluster region
CANCER GENETICS AND CYTOGENETICS
Complete karyotype characterization of the K562 cell line by combined application of G-banding, multiplex-fluorescence in situ hybridization, fluorescence in situ hybridization, and comparative genomic hybridization
LEUKEMIA RESEARCH
Allogeneic bone marrow transplantation in first remission rescues childrenwith Philadelphia chromosome-positive acute lymphoblastic leukemia: Tokyo Children's Cancer Study Group (TCCSG) studies L89-12 and L92-13
MEDICAL AND PEDIATRIC ONCOLOGY
Unusual cause of extradural haemorrhage
MEDICAL AND PEDIATRIC ONCOLOGY
Detection of trisomy 8 in Philadelphia chromosome-positive CML patients using conventional cytogenetic and interphase fluorescence in situ hybridization techniques and its relation to c-myc involvement
ANNALS OF CLINICAL AND LABORATORY SCIENCE
The role of Bcr-Abl in chronic myeloid leukemia and stem cell biology
SEMINARS IN HEMATOLOGY
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
SCIENCE
Deletion of the Src homology 3 domain and C-terminal proline-rich sequences in Bcr-Abl prevents Abl interactor 2 degradation and spontaneous cell migration and impairs leukemogenesis
JOURNAL OF BIOLOGICAL CHEMISTRY
BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27(Kip1) expression
JOURNAL OF BIOLOGICAL CHEMISTRY
Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes
JOURNAL OF BIOLOGICAL CHEMISTRY
Direct relation between BCR-ABL tyrosine kinase activity and cyclin D2 expression in lymphoblasts
CANCER RESEARCH
Requirement for Mdm2 in the survival effects of Bcr-Abl and interleukin 3 in hematopoietic cells
CANCER RESEARCH
Expression of a truncated first exon BCR sequence in chronic myelogenous leukemia cells blocks cell growth and induces cell death
CANCER RESEARCH
Leukemogenesis and new therapy development: the example of chronic myelogenous leukemia
BULLETIN DU CANCER
Early response to chemotherapy as a prognostic factor in childhood acute lymphoblastic leukaemia: a methodological review
BRITISH JOURNAL OF HAEMATOLOGY
The association of severe aplastic anaemia with the Philadelphia chromosome and the BCR/ABL transcript
BRITISH JOURNAL OF HAEMATOLOGY
Recent advances in the molecular and cellular biology of chronic myeloid leukaemia: Lessons to be learned from the laboratory
BRITISH JOURNAL OF HAEMATOLOGY
In vitro drug resistance and prognostic impact of p16(INK4A)/p15(INK4B) deletions in childhood T-cell acute lymphoblastic leukaemia
BRITISH JOURNAL OF HAEMATOLOGY
Adhesion to fibronectin selectively protects Bcr-Abl(+) cells from DNA damage-induced apoptosis
BLOOD
Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein
BLOOD
A model of human p210(bcr/ABL)-mediated chronic myelogenous leukemia by transduction of primary normal human CD34(+) cells with a BCR/ABL-containing retroviral vector
BLOOD
In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents
BLOOD
Comparison of effects of the tyrosine kinase inhibitors AG957, AG490, and STI571 on BCR-ABL-expressing cells, demonstrating synergy between AG490 andSTI571
BLOOD
Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia
BLOOD
Induction of myeloproliferative disease in mice by tyrosine kinase fusion oncogenes does not require granulocyte-macrophage colony-stimulating factoror interleukin-3
BLOOD
The SH2 domain of Bcr-Abl is not required to induce a murine myeloproliferative disease; however, SH2 signaling influences disease latency and phenotype
BLOOD
Preparation and application of antibodies to phosphoamino acid sequences
BIOPOLYMERS
Detection of cyclin D1 overexpression by real-time reverse-transcriptase-mediated quantitative polymerase chain reaction for the diagnosis of mantle cell lymphoma
AMERICAN JOURNAL OF PATHOLOGY
Masked antisense: a molecular configuration for discriminating similar RNAtargets
EMBO REPORTS
Allogeneic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
Retroviral coexpression of IFN-alpha and IFN-gamma genes and inhibitory effects in chronic myeloid leukemia cells
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
Detailed mapping of methylcytosine positions at the CpG island surroundingthe Pa promoter at the bcr-abl locus in CML patients and in two cell lines, K562 and BV173
BLOOD CELLS MOLECULES AND DISEASES
Effect of the bcr/abl kinase inhibitors AG957 and NSC 680410 on chronic myelogenous leukemia cells in vitro
CLINICAL CANCER RESEARCH
The effect of Bcr-Abl protein tyrosine kinase on maturation and proliferation of primitive haematopoietic cells
MOLECULAR MEDICINE
Consequences of BCR-ABL expression within the hematopoietic stem cell in chronic myeloid leukemia
STEM CELLS
Comparison of a multiplex reverse transcriptase-polymerase chain reaction for BCR-ABL to fluorescence in situ hybridization, southern blotting, and conventional cytogenetics in the monitoring of patients with Ph1-positive leukemias
DIAGNOSTIC MOLECULAR PATHOLOGY
Clinical and epidemiological features of acute lymphoblastic leukemia following a previous malignancy
LEUKEMIA & LYMPHOMA
An in vivo and in vitro comparison of the effects of b2-a2 and b3-a2 p210BCR-ABL splice variants on murine 32D cells
LEUKEMIA & LYMPHOMA
Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia
LEUKEMIA & LYMPHOMA
Working at the cutting edge: the creation of allosteric ribozymes
STRUCTURE
Early events in leukemogenesis in P190Bcr-abl transgenic mice
ONCOGENE
Progressive changes in the leukemogenic signaling in BCR/ABL-transformed cells
ONCOGENE
Altered natural killer cell differentiation in CD34(+) progenitors from chronic myeloid leukemia patients
ONCOGENE
The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive chronic myeloid leukemia correlates with the disease stage
ANNALS OF HEMATOLOGY
A case of chronic myeloid leukemia with minor bcr-abl transcript followingfluorouracil therapy for esophageal carcinoma
ANNALS OF HEMATOLOGY
Molecular cytogenetics of stem cells: Target cells of chromosome aberrations as revealed by the application of fluorescence in situ hybridization to fluorescence-activated cell sorting
INTERNATIONAL JOURNAL OF HEMATOLOGY
Morphological and cytogenetic changes in therapy-related leukemia developed in a t(8;21)-acute myeloid leukemia (M2) patient: Sequential cytogenetic and molecular analyses
INTERNATIONAL JOURNAL OF HEMATOLOGY
Acute lymphoblastic leukaemia in puberty and adolescence
ANNALS OF ONCOLOGY
Cytogenetic and FISH studies of a single center consecutive series of 152 childhood acute lymphoblastic leukemias
EUROPEAN JOURNAL OF HAEMATOLOGY