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Inhibition of aspartate transcarbamylase by a phenobarbital derivative
JOURNAL OF ENZYME INHIBITION
A duplicated HNF-3 binding site in the CYP2H2 promoter underlies the weak phenobarbital induction response
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Reversibility and persistence of di-2-ethylhexyl phthalate (DEHP)- and phenobarbital-induced hepatocellular changes in rodents
TOXICOLOGICAL SCIENCES
Antiepileptic hypersensitivity syndrome in children
ANNALS OF PHARMACOTHERAPY
Role reversal: new insights from new ligands for the xenobiotic receptor CAR
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Do fits really beget fits? The effect of previous epileptic activity on the subsequent induction of the tetanus toxin model of limbic epilepsy in therat
NEUROBIOLOGY OF DISEASE
Expression and regulation of CYP6D3 in the house fly, Musca domestica (L.)
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
Cytochrome P450s CYP6D3 and CYP6D1 are part of a P450 gene cluster on autosome 1 in the house fly
INSECT MOLECULAR BIOLOGY
Organization, structure and evolution of the CYP2 gene cluster on human chromosome 19
PHARMACOGENETICS
Selective pressure during tumor promotion by phenobarbital leads to clonaloutgrowth of beta-catenin-mutated mouse liver tumors
ONCOGENE
Para-nitropbenol glucuronidation and sulfation in rat and human liver slices
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
Cytochrome P450 (P450) isoforms expression, P450 concentration, monooxygenase activities, reactive oxygen species formation, lipid peroxidation, and glutathione content in wild catch carp and tench liver - influence of a twoweeks exposure to phenobarbital
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
Mechanism of carbon tetrachloride-induced hepatotoxicity. Hepatocellular damage by reactive carbon tetrachloride metabolites
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
Antiepileptic drugs as independent predictors of plasma total homocysteinelevels
EPILEPSY RESEARCH
Comparison the cognitive effect of anti-epileptic drugs in seizure-free children with epilepsy before and after drug withdrawal
EPILEPSY RESEARCH
Effect of experimental renal failure on the pharmacodynamics of cefoselis-induced seizures in rats
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Hair analysis for pharmaceutical drugs. I. Effective extraction and determination of phenobarbital, phenytoin and their major metabolites in rat and human hair
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Measures of psychopathology in children with complex partial seizures and primary generalized epilepsy with absence
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, andpregnane X receptor, from birds to humans
MOLECULAR ENDOCRINOLOGY
Differential induction of glutathione S-transferases in the clam Ruditapesdecussatus exposed to organic compounds
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
1 alpha,25-dihydroxyvitamin D-3 inhibits rat liver ultrastructural changesin diethylnitrosamine-initiated and phenobarbital promoted rat hepatocarcinogenesis
JOURNAL OF CELLULAR BIOCHEMISTRY
Involvement of mu class glutathione S-transferase subunit M-2 (rGST M-2) levels in the initiation and promotion of hepatocellular carcinogenesis in old rats
EXPERIMENTAL GERONTOLOGY
Phenobarbital determination and its kinetic analysis by a surface plasmon resonance sensor with an immobilized antibody
BUNSEKI KAGAKU
Carbamazepine in phenobarbital-nonresponders: experience with ten preterm infants
EUROPEAN JOURNAL OF PEDIATRICS
Cumulative exposure to tamoxifen: DNA adducts and liver cancer in the rat
ARCHIVES OF TOXICOLOGY
Morphology and cytochrome P450 isoforms expression in precision-cut rat liver slices
TOXICOLOGY
The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver
MOLECULAR AND CELLULAR BIOLOGY
Xenobiotic induction of cytochrome P4502B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1
BIOCHEMICAL JOURNAL
Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes
ATLA-ALTERNATIVES TO LABORATORY ANIMALS
Synergistic protection of allopregnanolone and phenobarbital against maximal electroshock seizures in mice
ACTA PHARMACOLOGICA SINICA
Influence of antioxydants and phenobarbital on enzymes of metabolic activation of cyclophosphamide in rats
EXPERIMENTAL ONCOLOGY
Effects of microsomal enzyme inducers on thyroid follicular cell proliferation and thyroid hormone metabolism
TOXICOLOGIC PATHOLOGY
Theoretical approaches to physical transformations of active pharmaceutical ingredients during manufacturing processes
ADVANCED DRUG DELIVERY REVIEWS
Pharmacokinetics of phenobarbital during certain enhanced elimination modalities to evaluate their clinical efficacy in management of drug overdose
THERAPEUTIC DRUG MONITORING
P-hydroxylation of phenobarbital: Relationship to (s)-mephenytoin hydroxylation (CYP2C19) polymorphism
THERAPEUTIC DRUG MONITORING
Role of transforming growth factor alpha and prostaglandins in preferential growth of preneoplastic rat hepatocytes
CARCINOGENESIS
Isolation and sequencing of the cDNA of a novel cytochrome P450 from rat oesophagus
CARCINOGENESIS
Management of paracetamol overdose - Current controversies
DRUG SAFETY
Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
The treatment of epilepsy in developing countries: where do we go from here?
BULLETIN OF THE WORLD HEALTH ORGANIZATION
Effect of hypophysectomy and growth hormone replacement on the modulation of P450 expression after treatment with the aromatic hydrocarbon ethylbenzene
TOXICOLOGY AND APPLIED PHARMACOLOGY
Feasibility of using isothermal microcalorimetry to evaluate the physical stability of amorphous nifedipine and phenobarbital
THERMOCHIMICA ACTA
Effect of phenobarbital on antioxidant enzyme activities and blood gas parameters in Balb/C mice
REVUE DE MEDECINE VETERINAIRE
No effect of phenobarbital pretreatment of rats on methotrexate pharmacokinetics in the isolated liver perfused in a single-pass way
PHARMACOLOGY
Drug-induced hypersensitivity syndrome in pediatric patients
PEDIATRICS
Multiple enhancer units mediate drug induction of CYP2H1 by xenobiotic-sensing orphan nuclear receptor chicken xenobiotic receptor
MOLECULAR PHARMACOLOGY
Orphan receptor promiscuity in the induction of cytochromes P450 by xenobiotics
JOURNAL OF BIOLOGICAL CHEMISTRY
Regulation of phenobarbital-mediated induction of CYP102 (Cytochrome P450(BM-3)) in Bacillus megaterium by phytochemicals from soy and green tea
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Brain responses to acute withdrawal in phenobarbital-dependent rats
EUROPEAN JOURNAL OF PHARMACOLOGY
Influence of phenobarbital on changes in Na+ handling, hemodynamics and liver function due to partial portal vein ligation in rats
EUROPEAN JOURNAL OF PHARMACOLOGY
Incidence of drug-induced aggravation in benign epilepsy with centrotemporal spikes
EPILEPSIA
Enhanced anticonvulsant activity of neuroactive steroids in a rat model ofcatamenial epilepsy
EPILEPSIA
Application of micro-column HPLC to the determination of phenobarbital andcarbamazepine in human blood serum
CHROMATOGRAPHIA
Phenobarbital inducibility and differences in protein expression of an animal model
CHEMICO-BIOLOGICAL INTERACTIONS
A clonal growth model: Time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay
CANCER RESEARCH
Differential effects of phenobarbital on the constitutive and inducible expression of P4502B and 3A subfamilies in sheep tissues
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Wyeth 14,643, at the lambda cII locus in Big Blue (R) transgenic mice
BIOCHEMICAL PHARMACOLOGY
Sex-associated expression of mouse hepatic and renal CYP2B enzymes by glucocorticoid hormones
BIOCHEMICAL PHARMACOLOGY
Functional analysis of the phenobarbital-responsive unit in rat CYP2B2
BIOCHEMICAL PHARMACOLOGY
Induction of cytochrome P4502B1 by pyrethroids in primary rat hepatocyte cultures
BIOCHEMICAL PHARMACOLOGY
Oxidative hydrolysis of scoparone by cytochrome P450CYP2C29 reveals a novel metabolite
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
cAMP mediated upregulation of CYP2A5 in mouse hepatocytes
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Perinatal factors associated with severe intracranial hemorrhage
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Immunoassay-based determination of phenobarbital using size-exclusion chromatography
JOURNAL OF CHROMATOGRAPHY B
Subchronic administration of phenobarbital alters the mutation spectrum oflacI in the livers of Big Blue (R) transgenic mice
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Early detection of carcinogenic substances and modifiers in rats
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
Differential effects of microsomal enzyme inducers on in vitro thyroxine (T-4) and triiodothyronine (T-3) glucuronidation
TOXICOLOGICAL SCIENCES
Xenobiotics modulate the p53 response to DNA damage in preneoplastic enzyme-altered foci in rat liver; Effects of diethylnitrosamine and phenobarbital
TOXICOLOGICAL SCIENCES
Results of barbiturate antiepileptic drug discontinuation on antipsychoticmedication dose in individuals with intellectual disability
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
Treatment of carbon tetrachloride and phenobarbital-induced chronic liver failure with intrasplenic hepatocyte transplantation
CELL TRANSPLANTATION
Oral bioavailability of phenobarbital: a comparison of a solution in myvacet 9-08, a suspension, and a tablet
PHARMACY WORLD & SCIENCE
Clinical pharmacokinetics of phenobarbital in neonates
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Induction of drug metabolism by nuclear receptor CAR: molecular mechanismsand implications for drug research
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Ketamine controls prolonged status epilepticus
EPILEPSY RESEARCH
The role of technical, biological, and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. VII. Seasonal influences on anticonvulsant drug actions in mouse models of generalized seizures
EPILEPSY RESEARCH
Amplifing effect of dietary taurine on the induction of cytochrome P-450 and on the urinary excretion of ascorbic acid in rats fed on phenobarbital-containing diets
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Thyroid hyperactivity induced by methimazole, spironolactone and phenobarbital in marmosets (Callithrix jacchus): Histopathology, plasma thyroid hormone levels and hepatic T-4 metabolism
JOURNAL OF VETERINARY MEDICAL SCIENCE
Establishment and characterization of a cell line from a chemically-induced mouse hepatoblastoma
JOURNAL OF VETERINARY MEDICAL SCIENCE
Apoptosis and cell proliferation in rat hepatocytes induced by barbiturates
JOURNAL OF VETERINARY MEDICAL SCIENCE
Effects of long-term phenobarbital treatment on the thyroid and adrenal axis and adrenal function tests in dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE
Effects of long-term phenobarbital treatment on the liver in dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE
Reciprocal activation of Xenobiotic response genes by nuclear receptors SXR/PXR and CAR
GENES & DEVELOPMENT
Estrogen activation of the nuclear orphan receptor CAR (Constitutive active receptor) in induction of the mouse Cyp2b10 gene
MOLECULAR ENDOCRINOLOGY
Phenobarbital induction of UDP-glucosyltransferase activity in Drosophila melanogaster Meigen
JOURNAL OF ENTOMOLOGICAL SCIENCE
Regulation of phenobarbital-induction of CYP2B and CYP3A genes in rat cultured hepatocytes: involvement of several serine/threonine protein kinases and phosphatases
CELL BIOLOGY AND TOXICOLOGY
Seizure-inducing paradoxical reaction to antiepileptic drugs
BRAIN & DEVELOPMENT
Prolonged phenobarbital pretreatment abolishes the early oxidative stress component induced in the liver by acute lindane intoxication
TOXICOLOGY LETTERS
Induction of drug metabolising enzymes - Pharmacokinetic and toxicologicalconsequences in humans
CLINICAL PHARMACOKINETICS
Functional interactions between an atypical NF-kappa B site from the rat CYP2B1 promoter and the transcriptional repressor RBP-J kappa/CBF1
NUCLEIC ACIDS RESEARCH
Barbiturates inhibit K+-evoked noradrenaline and dopamine release from ratstriatal slices - involvement of voltage sensitive Ca2+ channels
NEUROSCIENCE LETTERS
Induction of cytochrome P4502B1-mRNA and pentoxyresorufin O-depentylation after exposure of precision-cut rat liver slices to phenobarbital
TOXICOLOGY
Effectiveness of hemodialysis in the extracorporeal therapy of phenobarbital overdose
AMERICAN JOURNAL OF KIDNEY DISEASES
Metabolism of toluene and trichloroethylene in laboratory rats, pretreatedwith phenobarbital.
JOURNAL OF ENVIRONMENTAL BIOLOGY
Liver tumor-promoting effect of beta-naphthoflavone, a strong CYP 1A1/2 inducer, and the relationship between CYP 1A1/2 induction and Cx32 decrease in its hepatocarcinogenesis in the rat
TOXICOLOGIC PATHOLOGY
Paradoxical effects of phenobarbital on mouse hepatocarcinogenesis
TOXICOLOGIC PATHOLOGY
Neural grafting reverses prenatal drug-induced alterations in hippocampal PKC and related behavioral deficits
DEVELOPMENTAL BRAIN RESEARCH
Neurobehavioral damage to cholinergic systems caused by prenatal exposure to heroin or phenobarbital: Cellular mechanisms and the reversal of deficits by neural grafts
DEVELOPMENTAL BRAIN RESEARCH
Antiepileptogenic properties of phenobarbital: behavior and neurochemical analysis
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Comparison of effect of ethanol and anticonvulsants on cardiovascular drug-modified cocaine toxicity
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
Cell biology of cytochrome P-450 in the liver
INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 198