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La ricerca find articoli where soggetti phrase all words 'PHARMACOGENETICS' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 521 riferimenti
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    1. Evans, WE; Johnson, JA
      Pharmacogenomics: The inherited basis for interindividual differences in drug response

      ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS
    2. Bauman, JL
      The role of pharmacokinetics, drug interactions and pharmacogenetics in the acquired long QT syndrome

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    3. Pillans, PI
      Increasing relevance of pharmacogenetics of drug metabolism in clinical practice

      INTERNAL MEDICINE JOURNAL
    4. Saito, S; Iida, A; Sekine, A; Miura, Y; Sakamoto, T; Ogawa, C; Kawauchi, S; Higuchi, S; Nakamura, Y
      Identification of 197 genetic variations in six human methyltransferase genes in the Japanese population

      JOURNAL OF HUMAN GENETICS
    5. Pike, MG; Franklin, CL; Mays, DC; Lipsky, JJ; Lowry, PW; Sandborn, WJ
      Improved methods for determining the concentration of 6-thioguanine nucleotides and 6-methylmercaptopurine nucleotides in blood

      JOURNAL OF CHROMATOGRAPHY B
    6. Weber, WW
      The legacy of pharmacogenetics and potential applications

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    7. Tomlinson, IPM; Ilyas, M
      Molecular pathology of solid tumours: some practical suggestions for translating research into clinical practice

      JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
    8. Jazwinska, EC
      Exploiting human genetic variation in drug discovery and development

      DRUG DISCOVERY TODAY
    9. Arranz, MJ; Mancama, D; Kerwin, RW
      Neurotransmitter receptor variants and their influence on antipsychotic treatment (Review)

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    10. Raida, M; Schwabe, W; Hausler, P; Van Kuilenburg, ABP; Van Gennip, AH; Behnke, D; Hoffken, K
      Prevalence of a common point mutation in the Dihydropyrimidine dehydrogenase (DPD) gene within the 5 '-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls

      CLINICAL CANCER RESEARCH
    11. van Kuilenburg, ABP; Muller, EW; Haasjes, J; Meinsma, R; Zoetekouw, L; Waterham, HR; Baas, F; Richel, DJ; van Gennip, AH
      Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: Frequency of thecommon IVS14+1G > A mutation causing DPD deficiency

      CLINICAL CANCER RESEARCH
    12. Chang, CC; Hsieh, YY; Chung, JG; Tsai, HD; Tsai, CH
      Kinetics of acetyl coenzyme A: Arylamine N-acetyltransferase from human cumulus cells

      JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
    13. Zheng, W; Xie, DW; Cerhan, JR; Sellers, TA; Wen, WQ; Folsom, AR
      Sulfotransferase 1A1 polymorphism, endogenous estrogen exposure, well-donemeat intake, and breast cancer risk

      CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
    14. Thervet, E; Anglicheau, D; Toledano, N; Houllier, AM; Noel, LH; Kreis, H; Beaune, P; Legendre, C
      Long-term results of TPMT activity monitoring in azathioprine-treated renal allograft recipients

      JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
    15. Wang, L; Yan, L; McGuire, C; Kozak, CA; Wang, M; Kim, UJ; Siciliano, M; Weinshilboum, RM
      Mouse histamine N-methyltransferase: cDNA cloning, expression, gene cloning and chromosomal localization

      INFLAMMATION RESEARCH
    16. Horton, JR; Sawada, K; Nishibori, M; Zhang, X; Cheng, XD
      Two polymorphic forms of human histamine methyltransferase: Structural, thermal and kinetic comparisons

      STRUCTURE
    17. Lang, T; Klein, K; Fischer, J; Nussler, AK; Neuhaus, P; Hofmann, U; Eichelbaum, M; Schwab, M; Zanger, UM
      Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

      PHARMACOGENETICS
    18. Xie, HG; Dishy, V; Sofowora, G; Kim, RB; Landau, R; Smiley, RM; Zhou, HH; Wood, AJJ; Harris, P; Stein, CM
      Arg(389)Gly beta(1)-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo

      PHARMACOGENETICS
    19. Fretland, AJ; Leff, MA; Doll, MA; Hein, DW
      Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms

      PHARMACOGENETICS
    20. Ameyaw, MM; Regateiro, F; Li, T; Liu, XH; Tariq, M; Mobarek, A; Thornton, N; Folayan, GO; Githang'a, J; Indalo, A; Ofori-Adjei, D; Price-Evans, DA; McLeod, HL
      MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

      PHARMACOGENETICS
    21. Ando, M; Ando, Y; Hasegawa, Y; Sekido, Y; Shimokata, K; Horibe, K
      Genetic polymorphisms of thiopurine S-methyltransferase and 6-mercaptopurine toxicity in Japanese children with acute lymphoblastic leukaemia

      PHARMACOGENETICS
    22. Kumagai, K; Hiyama, K; Ishioka, S; Sato, H; Yamanishhi, Y; McLeod, HL; Konishi, F; Maeda, H; Yamakido, M
      Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese

      PHARMACOGENETICS
    23. Carlini, EJ; Raftogianis, RB; Wood, TC; Jin, F; Zheng, W; Rebbeck, TR; Weinshilboum, RM
      Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects

      PHARMACOGENETICS
    24. Nowotny, P; Kwon, JM; Goate, AM
      SNP analysis to dissect human traits

      CURRENT OPINION IN NEUROBIOLOGY
    25. Iacoviello, L; Donati, MB
      Gene-environment interactions: The example of coagulation factors

      NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
    26. Catalano, M
      Functionally gene-linked polymorphic regions and genetically controlled neurotransmitters metabolism

      EUROPEAN NEUROPSYCHOPHARMACOLOGY
    27. Lesch, KP
      Variation of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic drugs

      EUROPEAN NEUROPSYCHOPHARMACOLOGY
    28. Hurko, O
      Genetics and genomics in neuropsychopharmacology: the impact on drug discovery and development

      EUROPEAN NEUROPSYCHOPHARMACOLOGY
    29. Serretti, A; Zanardi, R; Cusin, C; Rossini, D; Lorenzi, C; Smeraldi, E
      Tryptophan hydroxylase gene associated with paroxetine antidepressant activity

      EUROPEAN NEUROPSYCHOPHARMACOLOGY
    30. Katsuya, T; Iwashima, Y; Sugimoto, K; Motone, M; Asai, T; Fukuda, M; Fu, YX; Hatanaka, Y; Ohishi, M; Rakugi, H; Higaki, J; Ogihara, T
      Effects of antihypertensive drugs and gene variants in the renin-angiotensin system

      Hypertension research
    31. Rodgers, HC; Knox, AJ
      Pharmacological treatment of the biochemical defect in cystic fibrosis airways

      EUROPEAN RESPIRATORY JOURNAL
    32. Weber, WW
      Effect of pharmacogenetics on medicine

      ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
    33. Dervieux, T; Medard, Y; Verpillat, P; Guigonis, V; Duval, M; Lescoeur, B; Suciu, S; Vilmer, E; Jacqz-Aigrain, E
      Possible implication of thiopurine S-methyltransferase in occurrence of infectious episodes during maintenance therapy for childhood lymphoblastic leukemia with mercaptopurine

      LEUKEMIA
    34. Wallace, TM; van Zanten, SJOV
      Frequency of use and standards of care for the use of azathioprine and 6-mercaptopurine in the treatment of inflammatory bowel disease: A systematic review of the literature and a survey of Canadian gastroenterologists

      CANADIAN JOURNAL OF GASTROENTEROLOGY
    35. Evans, WE; Hon, YY; Bomgaars, L; Coutre, S; Holdsworth, M; Janco, R; Kalwinsky, D; Keller, F; Khatib, Z; Margolin, J; Murray, J; Quinn, J; Ravindranath, Y; Ritchey, K; Roberts, W; Rogers, ZR; Schiff, D; Steuber, C; Tucci, F; Kornegay, N; Krynetski, EY; Relling, MV
      Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

      JOURNAL OF CLINICAL ONCOLOGY
    36. Ingelman-Sundberg, M
      Genetic variability in susceptibility and response to toxicants

      TOXICOLOGY LETTERS
    37. Park, BK; Pirmohamed, M
      Toxicogenetics in drug development

      TOXICOLOGY LETTERS
    38. Festing, MFW
      Experimental approaches to the determination of genetic variability

      TOXICOLOGY LETTERS
    39. Xie, HG; Kim, RB; Wood, AJJ; Stein, CM
      Molecular basis of ethnic differences in drug disposition and response

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    40. Quinzii, C; Belpinati, F; Pignatti, PF
      Predictive genetic testing - New possibilities in determination of risk ofcomplex diseases

      CROATIAN MEDICAL JOURNAL
    41. Saijo, N; Tamura, T; Yamamoto, N; Nishio, K
      New strategies for cancer therapy in the 21st century

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    42. Kocabas, NA; Karakaya, AE; Cholerton, S; Sardas, S
      Catechol-O-methyltransferase (COMT) genetic polymorphism in a Turkish population

      ARCHIVES OF TOXICOLOGY
    43. Meggitt, SJ; Reynolds, NJ
      Azathioprine for atopic dermatitis

      CLINICAL AND EXPERIMENTAL DERMATOLOGY
    44. Lennard, L; Chew, TS; Lilleyman, JS
      Human thiopurine methyltransferase activity varies with red blood cell age

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    45. Chan, E; Lee, HS; Hue, SS
      Population pharmacokinetics of carbamazepine in Singapore epileptic patients

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    46. Kubota, T; Chiba, K
      Frequencies of thiopurine S-methyltransferase mutant alleles (TPMT*2, *3A,*3B and *3C) in 151 healthy Japanese subjects and the inheritance of TPMT*3C in the family of a propositus

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    47. Busquets, X; Agusti, AGN
      Gene chip (DNA array): the future is now!

      ARCHIVOS DE BRONCONEUMOLOGIA
    48. Ozdemir, V; Kalow, W; Okey, AB; Lam, MSM; Albers, LJ; Reist, C; Fourie, J; Posner, P; Collins, EJ; Roy, R
      Treatment-resistance to clozapine in association with ultrarapid CYP1A2 activity and the C -> A polymorphism in intron 1 of the CYP1A2 gene: Effect of grapefruit juice and low-dose fluvoxamine

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    49. Mason, C; Krueger, GG
      Thioguanine for refractory psoriasis: A 4-year experience

      JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
    50. Evans, KL; Muir, WJ; Blackwood, DHR; Porteous, DJ
      Nuts and bolts of psychiatric genetics: building on the Human Genome Project

      TRENDS IN GENETICS
    51. Hall, AG; Hamilton, P; Minto, L; Coulthard, SA
      The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase

      JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS
    52. Ozdemir, V; Basile, VS; Masellis, M; Kennedy, JL
      Pharmacogenetic assessment of antipsychotic-induced movement disorders: contribution of the dopamine D3 receptor and cytochrome P450 1A2 genes

      JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS
    53. Menor, C; Fueyo, JA; Escribano, O; Cara, C; Fernandez-Moreno, MD; Roman, ID; Guijarro, LG
      Determination of thiopurine methyltransferase activity in human erythrocytes by high-performance liquid chromatography: Comparison with the radiochemical method

      THERAPEUTIC DRUG MONITORING
    54. Foster, MW; Sharp, RR; Mulvihill, JJ
      Pharmacogenetics, race, and ethnicity: Social identities and individualized medical care

      THERAPEUTIC DRUG MONITORING
    55. Conti, CR
      Drug therapy tailored for the individual patient - Search for the holy grail

      CLINICAL CARDIOLOGY
    56. Lin, KM
      Biological differences in depression and anxiety across races and ethnic groups

      JOURNAL OF CLINICAL PSYCHIATRY
    57. Meirhaeghe, A; Helbecque, N; Cottel, D; Arveiler, D; Ruidavets, JB; Haas, B; Ferrieres, J; Tauber, JP; Bingham, A; Amouyel, P
      Impact of sulfonylurea receptor 1 genetic variability on non-insulin-dependent diabetes mellitus prevalence and treatment: A population study

      AMERICAN JOURNAL OF MEDICAL GENETICS
    58. Linder, MW; Valdes, R
      Genetic mechanisms for variability in drug response and toxicity

      JOURNAL OF ANALYTICAL TOXICOLOGY
    59. Crabbe, JC
      Use of genetic analyses to refine phenotypes related to alcohol tolerance and dependence

      ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
    60. Butcher, J
      Neurogenomics - a capital investment?

      LANCET
    61. Szefler, SJ
      Challenges in assessing outcomes for pediatric asthma

      JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
    62. Nebert, DW; Roe, AL
      Ethnic and genetic differences in metabolism genes and risk of toxicity and cancer

      SCIENCE OF THE TOTAL ENVIRONMENT
    63. Weyer, N; Kroplin, T; Fricke, L; Iven, H
      Human thiopurine S-methyltransferase activity in uremia and after renal transplantation

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    64. Lowenthal, A; Meyerstein, N; Ben-Zvi, Z
      Thiopurine methyltransferase activity in the Jewish population of Israel

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    65. Rossi, AM; Bianchi, M; Guarnieri, C; Barale, R; Pacifici, GM
      Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    66. Leeder, JS
      Pharmacogenetics and pharmacogenomics

      PEDIATRIC CLINICS OF NORTH AMERICA
    67. Sandborn, WJ
      The role of genetics (pharmacogenetics) in the treatment of inflammatory bowel disease in the future

      DRUGS OF TODAY
    68. Rusnak, JM; Kisabeth, RM; Herbert, DP; McNeil, DM
      Pharmacogenomics: Aa clinician's primer on emerging technologies for improved patient care

      MAYO CLINIC PROCEEDINGS
    69. Thomas, FJ; Hughes, TAT; Anstey, A
      Azathioprine treatment in multiple sclerosis; pretreatment assessment of metaboliser status

      JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
    70. Pedro-Botet, J; Schaefer, EJ; Bakker-Arkema, RG; Black, DM; Stein, EM; Corella, D; Ordovas, JM
      Apolipoprotein E genotype affects plasma lipid response to atorvastatin ina gender specific manner

      ATHEROSCLEROSIS
    71. Kitanaka, J; Kitanaka, N; Tsujimura, T; Kakihana, M; Terada, N; Takemura, M
      Guinea pig histamine N-methyltransferase: cDNA cloning and mRNA distribution

      JAPANESE JOURNAL OF PHARMACOLOGY
    72. Lowry, PW; Franklin, CL; Weaver, AL; Szumlanski, CL; Mays, DC; Loftus, EV; Tremaine, WJ; Lipsky, JJ; Weinshilboum, RM; Sandborn, WJ
      Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

      GUT
    73. Lowry, PW; Franklin, CL; Weaver, AL; Pike, MG; Mays, DC; Tremaine, WJ; Lipsky, JJ; Sandborn, WJ
      Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease

      GUT
    74. Schwab, M; Schaeffeler, E; Marx, C; Zanger, U; Aulitzky, W; Eichelbaum, M
      Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only

      GASTROENTEROLOGY
    75. Ophoff, RA; van den Maagdenberg, AMJM; Roon, KI; Ferrari, MD; Frants, RR
      The impact of pharmacogenetics for migraine

      EUROPEAN JOURNAL OF PHARMACOLOGY
    76. Alves, S; Amorim, A; Ferreira, F; Prata, MJ
      Influence of the variable number of tandem repeats located in the promoterregion of the thiopurine methyltransferase gene on enzymatic activity

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    77. Loennechen, T; Utsi, E; Hartz, I; Lysaa, R; Kildalsen, H; Aarbakke, J
      Detection of one single mutation predicts thiopurine S-methyltransferase activity in a population of Saami in northern Norway

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    78. Boulieu, R; Sauviat, M; Dervieux, T; Bertocchi, M; Mornex, JF
      Phenotype determination of thiopurine methyltransferase in erythrocytes byHPLC

      CLINICAL CHEMISTRY
    79. Hersberger, M; Marti-Juan, J; Rentsch, K; Hanseler, E
      Two single-tube tetra-primer assays to detect the CYP2C19*2 and*3 alleles of S-mephenytoin hydroxylase

      CLINICAL CHEMISTRY
    80. Nauck, M; Gierens, H; Marz, W; Wieland, H
      Rapid detection of a common dihydropyrimidine dehydrogenase mutation associated with 5-fluorouracil toxicity and congenital thymine uraciluria using fluorogenic hybridization probes

      CLINICAL BIOCHEMISTRY
    81. Schur, BC; Bjerke, J; Nuwayhid, N; Wong, SH
      Genotyping of cytochrome P450 2D6*3 and*4 mutations using conventional PCR

      CLINICA CHIMICA ACTA
    82. Steimer, W; Muller, B; Leucht, S; Kissling, W
      Pharmacogenetics: a new diagnostic tool in the management of antidepressive drug therapy

      CLINICA CHIMICA ACTA
    83. Zambon, A; Deeb, SS; Brown, BG; Hokanson, JE; Brunzell, JD
      Common hepatic lipase gene promoter variant determines clinical response to intensive lipid-lowering treatment

      CIRCULATION
    84. Dawling, S; Roodi, N; Mernaugh, RL; Wang, XH; Parl, FF
      Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: Comparison of wild-type and variant COMT isoforms

      CANCER RESEARCH
    85. Guichard, S; Canal, P
      New techniques and methods in cancer chemotherapy

      BULLETIN DU CANCER
    86. Kirby, B; Griffiths, CEM
      Psoriasis: the future

      BRITISH JOURNAL OF DERMATOLOGY
    87. Cunliffe, M
      Codeine phosphate in children: time for re-evaluation?

      BRITISH JOURNAL OF ANAESTHESIA
    88. Zanardi, R; Serretti, A; Rossini, D; Franchini, L; Cusin, C; Lattuada, E; Dotoli, D; Smeraldi, E
      Factors affecting fluvoxamine antidepressant activity: Influence of pindolol and 5-HTTLPR in delusional and nondelusional depression

      BIOLOGICAL PSYCHIATRY
    89. Phillips, RM; Burger, AM; Fiebig, HH; Double, JA
      Genotyping of NAD(P)H : quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo

      BIOCHEMICAL PHARMACOLOGY
    90. Lysaa, RA; Warren, DJ; Sylte, I; Aarbakke, J
      Effect of the glutathione/glutathione disulfide redox couple on thiopurinemethyltransferase

      BIOCHEMICAL PHARMACOLOGY
    91. Meinl, W; Glatt, H
      Structure and localization of the human SULT1B1 gene: Neighborhood to SULT1E1 and a SULT1D pseudogene

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    92. Geese, WJ; Raftogianis, RB
      Biochemical characterization and tissue distribution of human SULT2B1

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    93. Pang, YP; Zheng, XE; Weinshilboum, RM
      Theoretical 3D model of histamine N-methyltransferase: Insights into the effects of a genetic polymorphism on enzymatic activity and thermal stability

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    94. Roses, AD
      2025: The practice of neurology - Back from the future

      ARCHIVES OF NEUROLOGY
    95. Ritchie, MD; Hahn, LW; Roodi, N; Bailey, LR; Dupont, WD; Parl, FF; Moore, JH
      Multifactor-dimensionality reduction reveals high-order interactions amongestrogen-metabolism genes in sporadic breast cancer

      AMERICAN JOURNAL OF HUMAN GENETICS
    96. Kirchheiner, J; Brosen, K; Dahl, ML; Gram, LF; Kasper, S; Roots, I; Sjoqvist, F; Spina, E; Brockmoller, J
      CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages

      ACTA PSYCHIATRICA SCANDINAVICA
    97. Fagerlund, TH; Braaten, O
      No pain relief from codeine ...? An introduction to pharmacogenomics

      ACTA ANAESTHESIOLOGICA SCANDINAVICA
    98. Upton, A; Johnson, N; Sandy, J; Sim, E
      Arylamine N-acetyltransferases - of mice, men and microorganisms

      TRENDS IN PHARMACOLOGICAL SCIENCES
    99. Lucki, I; Dalvi, A; Mayorga, AJ
      Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice

      PSYCHOPHARMACOLOGY
    100. Emilien, G; Ponchon, M; Caldas, C; Isacson, O; Maloteaux, JM
      Impact of genomics on drug discovery and clinical medicine

      QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS


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Documento generato il 18/02/20 alle ore 14:35:50