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La ricerca find articoli where soggetti phrase all words 'PANCREATIC LIPASE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 476 riferimenti
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    1. Schulz, T; Schmid, RD; Pleiss, J
      Structural basis of stereoselectivity in Candida rugosa lipase-catalyzed hydrolysis of secondary alcohols

      JOURNAL OF MOLECULAR MODELING
    2. Beisson, F; Ferte, N; Bruley, S; Voultoury, R; Verger, R; Arondel, V
      Oil-bodies as substrates for lipolytic enzymes

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
    3. Lopez-Lopez, A; Castellote-Bargallo, AI; Lopez-Sabater, MC
      Direct determination by high-performance liquid chromatography of sn-2 monopalmitin after enzymatic lipase hydrolysis

      JOURNAL OF CHROMATOGRAPHY B
    4. Miled, N; Beisson, F; de Caro, J; de Caro, A; Arondel, V; Verger, R
      Interfacial catalysis by lipases'

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    5. Borreguero, I; Sanchez-Montero, JM; Sinisterra, JV; Rumbero, A; Hermoso, JA; Alcantara, AR
      Regioselective resolution of 1,n-diols catalysed by lipases: a rational explanation of the enzymatic selectivity

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    6. Zhu, K; Jutila, A; Tuominen, EKJ; Kinnunen, PKJ
      Effects of i-propanol on the structural dynamics of Thermomyces lanuginosalipase revealed by tryptophan fluorescence

      PROTEIN SCIENCE
    7. Zangenberg, NH; Mullertz, A; Kristensen, HG; Hovgaard, L
      A dynamic in vitro lipolysis model I. Controlling the rate of lipolysis bycontinuous addition of calcium

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    8. Sharma, S; Gupta, MN
      Alginate as a macroaffinity ligand and an additive for enhanced activity and thermostability of lipases

      BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
    9. Sek, L; Porter, CJH; Charman, WN
      Characterisation and quantification of medium chain and long chain triglycerides and their in vitro digestion products, by HPTLC coupled with in situdensitometric analysis

      JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    10. Bauer, VW; Squire, TL; Lowe, ME; Andrews, MT
      Expression of a chimeric retroviral-lipase mRNA confers enhanced lipolysisin a hibernating mammal

      AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
    11. Bruna, JM; Ordonez, JA; Fernandez, M; Herranz, B; de la Hoz, L
      Microbial and physico-chemical changes during the ripening of dry fermented sausages superficially inoculated with or having added an intracellular cell-free extract of Penicillium aurantiogriseum

      MEAT SCIENCE
    12. Han, LK; Kimura, Y; Kawashima, M; Takaku, T; Taniyama, T; Hayashi, T; Zheng, YN; Okuda, H
      Anti-obesity effects in rodents of dietary teasaponin, a lipase inhibitor

      INTERNATIONAL JOURNAL OF OBESITY
    13. Sayari, A; Agrebi, N; Jaoua, S; Gargouri, Y
      Biochemical and molecular characterization of Staphylococcus simulans lipase

      BIOCHIMIE
    14. van Dijk-van Aalst, K; Van Den Driessche, M; van der Schoor, S; Schiffelers, S; van't Westeinde, T; Ghoos, Y; Veereman-Wauters, G
      C-13 mixed triglyceride breath test: A noninvasive method to assess lipaseactivity in children

      JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
    15. Straarup, EM; Hoy, CE
      Lymphatic transport of fat in rats with normal- and malabsorption following intake of fats made from fish oil and decanoic acid. Effects of triacylglycerol structure

      NUTRITION RESEARCH
    16. Lombard, S; Helmy, ME; Pieroni, G
      Lipolytic activity of ricin from Ricinus sanguineus and Ricinus communis on neutral lipids

      BIOCHEMICAL JOURNAL
    17. Carriere, F; Renou, C; Ransac, S; Lopez, V; De Caro, J; Ferrato, F; De Caro, A; Fleury, A; Sanwald-Ducray, P; Lengsfeld, H; Beglinger, C; Hadvary, P; Verger, R; Laugier, R
      Inhibition of gastrointestinal lipolysis by Orlistat during digestion of test meals in healthy volunteers

      AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    18. Borel, P; Pasquier, B; Armand, M; Tyssandier, V; Grolier, P; Alexandre-Gouabau, MC; Andre, M; Senft, M; Peyrot, J; Jaussan, V; Lairon, D; Azais-Braesco, V
      Processing of vitamin A and E in the human gastrointestinal tract

      AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    19. Porter, CJH; Charman, WN
      In vitro assessment of oral lipid based formulations

      ADVANCED DRUG DELIVERY REVIEWS
    20. Chiou, A; Verger, R; Kokotos, G
      Synthetic routes and lipase-inhibiting activity of long-chain alpha-keto amides

      LIPIDS
    21. Goese, M; Eisenreich, W; Kupfer, E; Stohler, P; Weber, W; Leuenberger, HG; Bacher, A
      Biosynthesis of lipstatin. Incorporation of multiply deuterium-labeled (5Z,8Z)-tetradeca-5,8-dienoic acid and octanoic acid

      JOURNAL OF ORGANIC CHEMISTRY
    22. Jiang, YZ; Noh, SK; Koo, SI
      Egg phosphatidylcholine decreases the lymphatic absorption of cholesterol in rats

      JOURNAL OF NUTRITION
    23. Harrison, EH; Hussain, MM
      Mechanisms involved in the intestinal digestion and absorption of dietary vitamin A

      JOURNAL OF NUTRITION
    24. Koo, SI; Noh, SK
      Phosphatidylcholine inhibits and lysophosphatidylcholine enhances the lymphatic absorption of alpha-tocopherol in adult rats

      JOURNAL OF NUTRITION
    25. Keiper, T; Schneider, JG; Dugi, KA
      Novel site in lipoprotein lipase (LPL415-438) essential for substrate interaction and dimer stability

      JOURNAL OF LIPID RESEARCH
    26. Ikeda, Y; Takagi, A; Nakata, Y; Sera, Y; Hyoudou, S; Hamamoto, K; Nishi, Y; Yamamoto, A
      Novel compound heterozygous mutations for lipoprotein lipase deficiency: aG-to-T transversion at the first position of exon 5 causing G154V missensemutation and a 5 ' splice site mutation of intron 8

      JOURNAL OF LIPID RESEARCH
    27. Peelman, F; Vanloo, B; Verschelde, JL; Labeur, C; Caster, H; Taveirne, J; Verhee, A; Duverger, N; Vandekerckhove, J; Tavernier, J; Rosseneu, M
      Effect of mutations of N- and C-terminal charged residues on the activity of LCAT

      JOURNAL OF LIPID RESEARCH
    28. Dahim, M; Momsen, WE; Momsen, MM; Brockman, HL
      Specificity of the lipid-binding domain of apoC-II for the substrates and products of lipolysis

      JOURNAL OF LIPID RESEARCH
    29. Crandall, WV; Lowe, ME
      Colipase residues Glu(64) and Arg(65) are essential for normal lipase-mediated fat digestion in the presence of bile salt micelles

      JOURNAL OF BIOLOGICAL CHEMISTRY
    30. Ciuffreda, P; Loseto, A; Manzocchi, A; Santaniello, E
      Lipolytic activity of porcine pancreas lipase on fatty acid esters of dialkylglycerols: a structural basis for the design of new substrates for the assay of pancreatic lipases activity

      CHEMISTRY AND PHYSICS OF LIPIDS
    31. Tiss, A; Ransac, S; Lengsfeld, H; Hadvary, P; Cagna, A; Verger, R
      Surface behaviour of bile salts and tetrahydrolipstatin at air/water and oil/water interfaces

      CHEMISTRY AND PHYSICS OF LIPIDS
    32. Turner, NA; Needs, EC; Khan, JA; Vulfson, EN
      Analysis of conformational states of Candida rugosa lipase in solution: Implications for mechanism of interfacial activation and separation of open and closed forms

      BIOTECHNOLOGY AND BIOENGINEERING
    33. Peters, GH; Bywater, RP
      Influence of a lipid interface on protein dynamics in a fungal lipase

      BIOPHYSICAL JOURNAL
    34. Sugar, IP; Mizuno, NK; Momsen, MM; Brockman, HL
      Lipid lateral organization in fluid interfaces controls the rate of colipase association

      BIOPHYSICAL JOURNAL
    35. Lu, T; Ito, M; Tchoua, U; Takemori, H; Okamoto, M; Tojo, H
      Identification of essential residues for catalysis of rat intestinal phospholipase B/lipase

      BIOCHEMISTRY
    36. Gonzalez-Navarro, H; Bano, MC; Abad, C
      The closed/open model for lipase activation. Addressing intermediate active forms of fungal enzymes by trapping of conformers in water-restricted environments

      BIOCHEMISTRY
    37. Falt, H; Hernell, O; Blackberg, L
      Do human bile salt stimulated lipase and colipase-dependent pancreatic lipase share a common heparin-containing receptor?

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    38. Tiss, A; Carriere, F; Verger, R
      Effects of gum Arabic on lipase interfacial binding and activity

      ANALYTICAL BIOCHEMISTRY
    39. Augarten, A; Shmilovich, H; Doolman, R; Aviram, M; Akons, H; Ben Tur, L; Blau, H; Kerem, E; Rivlin, J; Sela, BA; Szeinberg, A; Yahav, Y
      Serum lipase levels as a diagnostic marker in cystic fibrosis patients with normal or borderline sweat tests

      PEDIATRIC PULMONOLOGY
    40. Ghosh, AK; Fidanze, S
      Asymmetric synthesis of (-)-tetrahydrolipstatin: An anti-aldol-based strategy

      ORGANIC LETTERS
    41. Billek, G
      Health aspects of thermoxidized oils and fats

      EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
    42. Beisson, F; Tiss, A; Riviere, C; Verger, R
      Methods for lipase detection and assay: a critical review

      EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
    43. Kovac, A; Scheib, H; Pleiss, J; Schmid, RD; Paltauf, F
      Molecular basis of lipase stereoselectivity

      EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
    44. Carrea, G; Riva, S
      Properties and synthetic applications of enzymes in organic solvents

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    45. Abousalham, A; Verger, R
      Egg yolk lipoproteins as substrates for lipases

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
    46. Villeneuve, P; Muderhwa, JM; Graille, J; Haas, MJ
      Customizing lipases for biocatalysis: a survey of chemical, physical and molecular biological approaches

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    47. Pogorevc, M; Faber, K
      Biocatalytic resolution of sterically hindered alcohols, carboxylic acids and esters containing fully substituted chiral centers by hydrolytic enzymes

      JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
    48. Carpino, PA
      Patent focus on new anti-obesity agents: September 1999-February 2000

      EXPERT OPINION ON THERAPEUTIC PATENTS
    49. Sanchez-Muniz, FJ; Arroyo, R; Sanchez-Montero, JM; Cuesta, C
      In vitro digestibility study of thermal oxidized palm oleins

      FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL
    50. Ronning, DR; Klabunde, T; Besra, GS; Vissa, VD; Belisle, JT; Sacchettini, JC
      Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines

      NATURE STRUCTURAL BIOLOGY
    51. Stobiecka, A
      The conformational changes of the fungal lipase from Humicola lanuginosa induced by the formation of bile salt and mixed micelles

      JOURNAL OF FLUORESCENCE
    52. Palekar, AA; Vasudevan, PT; Yan, S
      Purification of lipase: A review

      BIOCATALYSIS AND BIOTRANSFORMATION
    53. Miyazawa, T; Iwanaga, H; Ueji, S; Yamada, T
      Optical resolution of non-protein amino acids by lipase-catalyzed ester hydrolysis

      BIOCATALYSIS AND BIOTRANSFORMATION
    54. Schulz, T; Pleiss, J; Schmid, RD
      Stereoselectivity of Pseudomonas cepacia lipase toward secondary alcohols:A quantitative model

      PROTEIN SCIENCE
    55. Kokotos, G; Kotsovolou, S; Constantinou-Kokotou, V; Wu, GS; Olivecrona, G
      Inhibition of lipoprotein lipase by alkanesulfonyl fluorides

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    56. Whalen, LJ; Morrow, CJ
      Resolution of a chiral alcohol through lipase-catalyzed transesterification of its mixed carbonate by poly(ethylene glycol) in organic media

      TETRAHEDRON-ASYMMETRY
    57. Juhel, C; Armand, M; Pafumi, Y; Rosier, C; Vandermander, J; Lairon, D
      Green tea extract (AR25 (R)) inhibits lipolysis of triglycerides in gastric and duodenal medium in vitro

      JOURNAL OF NUTRITIONAL BIOCHEMISTRY
    58. Parsons, PJ; Cowell, JK
      A rapid synthesis of (-)-tetrahydrolipstatin

      SYNLETT
    59. Takagi, A; Ikeda, Y; Takeda, E; Yamamoto, A
      A newly identified lipoprotein lipase (LPL) gene mutation (F270L) in a Japanese patient with familial LPL deficiency

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    60. O'Connor, CJ; Manuel, RD
      Inhibiting the activity of calf pregastric lipase: Effect of bile salts, lecithin, liposomes, phenyl boronic acid and diethyl 4-nitrophenyl phosphate

      JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
    61. Peters, GH; Dahmen-Levison, U; de Meijere, K; Brezesinski, G; Toxvaerd, S; Mohwald, H; Svendsen, A; Kinnunen, PKJ
      Influence of surface properties of mixed monolayers on lipolytic hydrolysis

      LANGMUIR
    62. Hagen, BF; Naes, H; Holck, AL
      Meat starters have individual requirements for Mn2+

      MEAT SCIENCE
    63. Bruna, JR; Fernandez, M; Hierro, EM; Ordonez, JA; de la Hoz, L
      Combined use of Pronase E and a fungal extract (Penicillium aurantiogriseum) to potentiate the sensory characteristics of dry fermented sausages

      MEAT SCIENCE
    64. Han, LK; Sumiyoshi, M; Takeda, T; Chihara, H; Nishikiori, T; Tsujita, T; Kimura, Y; Okuda, H
      Inhibitory effects of chondroitin sulfate prepared from salmon nasal cartilage on fat storage in mice fed a high-fat diet

      INTERNATIONAL JOURNAL OF OBESITY
    65. Yamamoto, M; Shimura, S; Itoh, Y; Ohsaka, T; Egawa, M; Inoue, S
      Anti-obesity effects of lipase inhibitor CT-II, an extract from edible herbs, Nomame Herba, on rats fed a high-fat diet

      INTERNATIONAL JOURNAL OF OBESITY
    66. Sayari, A; Mejdoub, H; Gargouri, Y
      Characterization of turkey pancreatic lipase

      BIOCHIMIE
    67. Miled, N; Canaan, S; Dupuis, L; Roussel, A; Riviere, M; Carriere, F; de Caro, A; Cambillau, C; Verger, R
      Digestive lipases: From three-dimensional structure to physiology

      BIOCHIMIE
    68. Brockman, HL
      Kinetic behavior of the pancreatic lipase-colipase-lipid system

      BIOCHIMIE
    69. Fojan, P; Jonson, PH; Petersen, MTN; Petersen, SB
      What distinguishes an esterase from a lipase: A novel structural approach

      BIOCHIMIE
    70. Cajal, Y; Svendsen, A; De Bolos, J; Patkar, SA; Alsina, MA
      Effect of the lipid interface on the catalytic activity and spectroscopic properties of a fungal lipase

      BIOCHIMIE
    71. Heck, AM; Yanovski, JA; Calis, KA
      Orlistat, a new lipase inhibitor for the management of obesity

      PHARMACOTHERAPY
    72. Tan, S; Hooi, SC
      Syncollin is differentially expressed in rat proximal small intestine and regulated by feeding behavior

      AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    73. Minato, K; Shiroya, Y; Nakae, Y; Kondo, T
      The effect of chronic exercise on the rat pancreas

      INTERNATIONAL JOURNAL OF PANCREATOLOGY
    74. Svendsen, A
      Lipase protein engineering

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    75. Manetti, F; Mileto, D; Corelli, F; Soro, S; Palocci, C; Cernia, E; D'Acquarica, I; Lotti, M; Alberghina, L; Botta, M
      Design and realization of a tailor-made enzyme to modify the molecular recognition of 2-arylpropionic esters by Candida rugosa lipase

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    76. Miled, N; De Caro, A; De Caro, J; Verger, R
      A conformational transition between an open and closed form of human pancreatic lipase revealed by a monoclonal antibody

      BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
    77. Ikeda, Y; Goji, K; Takagi, A
      A compound heterozygote for a novel missense mutation (G 105R) in exon 3 and a missense mutation (D204E) in exon 5 of the lipoprotein lipase gene in a Japanese infant with hyperchylomicronaemia

      CLINICAL SCIENCE
    78. Paiva, AL; Balcao, VM; Malcata, FX
      Kinetics and mechanisms of reactions catalyzed by immobilized lipases

      ENZYME AND MICROBIAL TECHNOLOGY
    79. Szeto, TH; Wang, XH; Smith, R; Connor, M; Christie, MJ; Nicholson, GM; King, GF
      Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1

      TOXICON
    80. Liang, XF; Lohse, A; Bols, M
      Chemoenzymatic synthesis of isogalactofagomine

      JOURNAL OF ORGANIC CHEMISTRY
    81. Tafi, A; van Almsick, A; Corelli, F; Crusco, M; Laumen, KE; Schneider, MP; Botta, M
      Computer simulations of enantioselective ester hydrolyses catalyzed by Pseudomonas cepacia lipase

      JOURNAL OF ORGANIC CHEMISTRY
    82. Porsgaard, T; Hoy, CE
      Lymphatic transport in rats of several dietary fats differing in fatty acid profile and triacylglycerol structure

      JOURNAL OF NUTRITION
    83. Martin, JC; Sebedio, JL; Caselli, C; Pimont, C; Martine, L; Bernard, A
      Lymphatic delivery and in vitro pancreatic lipase hydrolysis of glycerol esters of conjugated linoleic acids in rats

      JOURNAL OF NUTRITION
    84. Han, LK; Xu, BJ; Kimura, Y; Zheng, YN; Okuda, H
      Platycodi radix affects lipid metabolism in mice with high fat diet-induced obesity

      JOURNAL OF NUTRITION
    85. Yang, YQ; Lowe, ME
      The open lid mediates pancreatic lipase function

      JOURNAL OF LIPID RESEARCH
    86. Bruna, JM; Fernandez, M; Hierro, EM; Ordonez, JA; De la Hoz, L
      Improvement of the sensory properties of dry fermented sausages by the superficial inoculation and/or the addition of intracellular extracts of Mucorracemosus

      JOURNAL OF FOOD SCIENCE
    87. Das, AK; Bellizzi, JJ; Tandel, S; Biehl, E; Clardy, J; Hofmann, SL
      Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride

      JOURNAL OF BIOLOGICAL CHEMISTRY
    88. Goese, M; Eisenreich, W; Kupfer, E; Weber, W; Bacher, A
      Biosynthetic origin of hydrogen atoms in the lipase inhibitor lipstatin

      JOURNAL OF BIOLOGICAL CHEMISTRY
    89. Ros, E
      Intestinal absorption of triglyceride and cholesterol. Dietary and pharmacological inhibition to reduce cardiovascular risk

      ATHEROSCLEROSIS
    90. Ashraf, H; Hildebrand, P; Meier, R; Beglinger, C; Gyr, N
      Induction of artificial fat maldigestion by tetrahydrolipstatin assessed by the C-13-hiolein breath test in healthy volunteers - A double-blind controlled pilot study

      DIGESTION
    91. Lin, GL; Lu, CP
      Conformational analysis of 1,2-di-O-octanoyl-ethylene-glycerol during aggregation

      JOURNAL OF THE CHINESE CHEMICAL SOCIETY
    92. Abousalham, A; Fotiadu, F; Buono, G; Verger, R
      Surface properties of unsaturated non-oxidized and oxidized free fatty acids spread as monomolecular films at an argon/water interface

      CHEMISTRY AND PHYSICS OF LIPIDS
    93. Honda, T; Endo, K; Ono, S
      Construction of an enantiomerically pure 6-substituted 3,5-syn-dihydroxyhexanoic acid system by an enantioselective deprotonation strategy: Formal synthesis of an antiobesity agent, (-)-tetrahydrolipstatin

      CHEMICAL & PHARMACEUTICAL BULLETIN
    94. Martinez, A; Malone, M; Hoeger, P; Palmer, R; Harper, JI
      Lipoatrophic panniculitis and chromosome 10 abnormality

      BRITISH JOURNAL OF DERMATOLOGY
    95. Cajal, Y; Svendsen, A; Girona, V; Patkar, SA; Alsina, MA
      Interfacial control of lid opening in Thermomyces lanuginosa lipase

      BIOCHEMISTRY
    96. MacPhee, CE; Hatters, DM; Sawyer, WH; Howlett, GJ
      Apolipoprotein C-II39-62 activates lipoprotein lipase by direct lipid-independent binding

      BIOCHEMISTRY
    97. Lookene, A; Nielsen, MS; Gliemann, J; Olivecrona, G
      Contribution of the carboxy-terminal domain of lipoprotein lipase to interaction with heparin and lipoproteins

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    98. Cavalier, JF; Buono, G; Verger, R
      Covalent inhibition of digestive lipases by chiral phosphonates

      ACCOUNTS OF CHEMICAL RESEARCH
    99. Selgas, MD; Casas, C; Toledo, VM; Garcia, ML
      Effect of selected mould strains on lipolysis in dry fermented sausages

      EUROPEAN FOOD RESEARCH AND TECHNOLOGY
    100. Marguet, F; Cavalier, JF; Verger, R; Buono, G
      New synthesis of sn-1,2-and sn-2,3-O-diacylglycerols application to the synthesis of enantiopure phosphonates analogous to triglycerides: A new classof inhibitors of lipases

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY


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Documento generato il 16/01/21 alle ore 08:17:44