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La ricerca find articoli where soggetti phrase all words 'P2Y(1) RECEPTOR' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 86 riferimenti
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    1. Jacobson, KA; Ravi, RG; Nandanan, E; Kim, HS; Moro, S; Kim, YC; Lee, K; Barak, D; Marquez, VE; Ji, XD
      Ribose modified nucleosides and nucleotides as ligands for purine receptors

      NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
    2. Savage, B; Cattaneo, M; Ruggeri, ZM
      Mechanisms of platelet aggregation

      CURRENT OPINION IN HEMATOLOGY
    3. Maayani, S; Schwarz, T; Craddock-Royal, B; Tagliente, TM
      Activation of the alpha(2A)-adrenoceptor mediates deceleration of the deaggregation component of the response to ADP or 5-HT in human platelets in vitro

      PLATELETS
    4. Maayani, S; Schwarz, T; Martinez, R; Tagliente, TM
      Activation of G(i)-coupled receptors releases a tonic state of inhibited platelet aggregation

      PLATELETS
    5. Cattaneo, M; Gachet, C
      The platelet ADP receptors

      HAEMATOLOGICA
    6. Lee, DK; Nguyen, T; Lynch, KR; Cheng, R; Vanti, WB; Arkhitko, O; Lewis, T; Evans, JF; George, SR; O'Dowd, BF
      Discovery and mapping of ten novel G protein-coupled receptor genes

      GENE
    7. Oury, C; Toth-Zsamboki, E; Thys, C; Tytgat, J; Vermylen, J; Hoylaerts, MF
      The ATP-gated P2X(1) ion channel acts as a positive regulator of platelet responses to collagen

      THROMBOSIS AND HAEMOSTASIS
    8. Gachet, C
      ADP receptors of platelets and their inhibition

      THROMBOSIS AND HAEMOSTASIS
    9. Rolf, MG; Brearley, CA; Mahaut-Smith, MP
      Platelet shape change evoked by selective activation of P2X(1) purinoceptors with alpha,beta-methylene ATP

      THROMBOSIS AND HAEMOSTASIS
    10. Hourani, SMO
      Discovery and recognition of purine receptor subtypes on platelets

      DRUG DEVELOPMENT RESEARCH
    11. Jacobson, KA
      Probing adenosine and P2 receptors: Design of novel purines and nonpurinesas selective ligands

      DRUG DEVELOPMENT RESEARCH
    12. Choi, RCY; Man, MLS; Ling, KKY; Ip, NY; Simon, J; Barnard, EA; Tsim, KWK
      Expression of the P2Y(1) nucleotide receptor in chick muscle: Its functional role in the regulation of acetylcholinesterase and acetylcholine receptor

      JOURNAL OF NEUROSCIENCE
    13. John, GR; Simpson, JE; Woodroofe, MN; Lee, SC; Brosnan, CF
      Extracellular nucleotides differentially regulate interleukin-1 beta signaling in primary human astrocytes: Implications for inflammatory gene expression

      JOURNAL OF NEUROSCIENCE
    14. Krugel, U; Kittner, H; Franke, H; Illes, P
      Stimulation of P2 receptors in the ventral tegmental area enhances dopaminergic mechanisms in vivo

      NEUROPHARMACOLOGY
    15. Hollopeter, G; Jantzen, HM; Vincent, D; Li, G; England, L; Ramakrishnan, V; Yang, RB; Nurden, P; Nurden, A; Julius, D; Conley, PB
      Identification of the platelet ADP receptor targeted by antithrombotic drugs

      NATURE
    16. Mellor, EA; Maekawa, A; Austen, KF; Boyce, JA
      Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    17. Hechler, BA; Toselli, P; Ravanat, C; Gachet, C; Ravid, K
      MpI ligand increases P2Y1 receptor gene expression in megakaryocytes with no concomitant change in platelet response to ADP

      MOLECULAR PHARMACOLOGY
    18. Moccia, F; Baruffi, S; Spaggiari, S; Coltrini, D; Berra-Romani, R; Signorelli, S; Castelli, L; Taglietti, V; Tanzi, F
      P-2Y1 and P-2Y2 receptor-operated Ca2+ signals in primary cultures of cardiac microvascular endothelial cells

      MICROVASCULAR RESEARCH
    19. Grobben, B; Claes, P; Van Kolen, K; Roymans, D; Fransen, P; Sys, SU; Slegers, H
      Agonists of the P2Y(AC)-receptor activate MAP kinase by a ras-independent pathway in rat C6 glioma

      JOURNAL OF NEUROCHEMISTRY
    20. Laitinen, JT; Uri, A; Raidaru, G; Miettinen, R
      [S-35]CTP gamma S autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor

      JOURNAL OF NEUROCHEMISTRY
    21. Wittenberger, T; Schaller, HC; Hellebrand, S
      An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors

      JOURNAL OF MOLECULAR BIOLOGY
    22. Schafferhans, A; Klebe, G
      Docking ligands onto binding site representations derived from proteins built by homology modelling

      JOURNAL OF MOLECULAR BIOLOGY
    23. Foster, CJ; Prosser, DM; Agans, JM; Zhai, Y; Smith, MD; Lachowicz, JE; Zhang, FL; Gustafson, E; Monsma, FJ; Wiekowski, MT; Abbondanzo, SJ; Cook, DN; Bayne, ML; Lira, SA; Chintala, MS
      Molecular identification and characterization of the platelet ADP receptortargeted by thienopyridine antithrombotic drugs

      JOURNAL OF CLINICAL INVESTIGATION
    24. Communi, D; Gonzalez, NS; Detheux, M; Brezillon, S; Lannoy, V; Parmentier, M; Boeynaems, JM
      Identification of a novel human ADP receptor coupled to G(i)

      JOURNAL OF BIOLOGICAL CHEMISTRY
    25. Zhang, FL; Luo, L; Gustafson, E; Lachowicz, J; Smith, M; Qiao, XD; Liu, YH; Chen, GD; Pramanik, B; Laz, TM; Palmer, K; Bayne, M; Monsma, FJ
      ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999

      JOURNAL OF BIOLOGICAL CHEMISTRY
    26. Ferreira, ZS; Markus, RP
      Characterisation of P2Y(1)-like receptor in cultured rat pineal glands

      EUROPEAN JOURNAL OF PHARMACOLOGY
    27. Baurand, A; Raboisson, P; Freund, M; Leon, C; Cazenave, JP; Bourguignon, JJ; Gachet, C
      Inhibition of platelet function by administration of MRS2179, a P2Y(1) receptor antagonist

      EUROPEAN JOURNAL OF PHARMACOLOGY
    28. Jung, SM; Moroi, M
      Platelet collagen receptor integrin alpha(2)beta(1) activation involves differential participation of ADP-receptor subtypes P2Y1 and P2Y12 but not intracellular calcium change

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    29. Gershengorn, MC; Osman, R
      Minireview: Insights into G protein-coupled receptor function using molecular models

      ENDOCRINOLOGY
    30. Sugidachi, A; Asai, F; Yoneda, K; Iwamura, R; Ogawa, T; Otsuguro, K; Koike, H
      Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type G(i)-linked P2T antagonist, CS-747

      BRITISH JOURNAL OF PHARMACOLOGY
    31. Simon, J; Vigne, P; Eklund, KM; Michel, AD; Carruthers, AM; Humphrey, PPA; Frelin, C; Barnard, EA
      Activity of adenosine diphosphates and triphosphates on a P2Y(T)-type receptor in brain capillary endothelial cells

      BRITISH JOURNAL OF PHARMACOLOGY
    32. Zundorf, G; Schafer, R; Vohringer, C; Halbfinger, E; Fischer, B; Reiser, G
      Novel modified adenosine 5 '-triphosphate analogues pharmacologically characterized in human embryonic kidney 293 cells highly expressing rat brain P2Y(1) receptor: biotinylated analogue potentially suitable for specific P2Y(1) receptor isolation

      BIOCHEMICAL PHARMACOLOGY
    33. Fischer, B; Shahar, L; Chulkin, A; Boyer, JL; Harden, KT; Gendron, FP; Beaudoin, AR; Chapal, J; Hillaire-Buys, D; Petit, P
      2-thioether-5 '-O-(1-thiotriphosphate)-adenosine derivatives: New insulin secretagogues acting through P2Y-receptors

      ISRAEL MEDICAL ASSOCIATION JOURNAL
    34. Offermanns, S
      The role of heterotrimeric G proteins in platelet activation

      BIOLOGICAL CHEMISTRY
    35. Cattaneo, M; Lecchi, A; Lombardi, R; Gachet, C; Zighetti, ML
      Platelets from a patient heterozygous for the defect of P2(CYC) receptors for ADP have a secretion defect despite normal thromboxane A(2) production and normal granule stores - Further evidence that some cases of platelet 'primary secretion defect' are heterozygous for a defect of P2(CYC) receptors

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    36. Jung, SM; Moroi, M
      Activation of the platelet collagen receptor integrin alpha 2 beta 1 - Itsmechanism and participation in the physiological functions of platelets

      TRENDS IN CARDIOVASCULAR MEDICINE
    37. Moore, D; Iritani, S; Chambers, J; Emson, P
      Immunohistochemical localization of the P2Y(1) purinergic receptor in Alzheimer's disease

      NEUROREPORT
    38. Wilde, JI; Retzer, M; Siess, W; Watson, SP
      ADP-induced platelet shape change: an investigation of the signalling pathways involved and their dependence on the method of platelet preparation

      PLATELETS
    39. Gachet, C
      Platelet activation by ADP: the role of ADP antagonists

      ANNALS OF MEDICINE
    40. Fischer, B
      P2-receptor agonists: From molecular recognition studies to potential clinical applications

      DRUG DEVELOPMENT RESEARCH
    41. Barnard, EA
      Imagination and reality in the search for the P2Y receptors

      JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
    42. Cusack, NJ; Hourani, SMO
      Platelet P2 receptors: from curiosity to clinical targets

      JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
    43. Kennedy, C
      The discovery and development of P2 receptor subtypes

      JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
    44. Fagura, MS; Jarvis, GE; Dougall, IG; Leff, P
      Adventures in the pharmacological analysis of P2 receptors

      JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
    45. von Kugelgen, I; Wetter, A
      Molecular pharmacology of P2Y-receptors

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    46. Malmsjo, M; Hou, MY; Harden, TK; Pendergast, W; Pantev, E; Edvinsson, L; Erlinge, D
      Characterization of contractile P2 receptors in human coronary arteries byuse of the stable pyrimidines uridine 5 '-O-thiodiphosphate and uridine 5 '-O-3-thiotriphosphate

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    47. Dangelmaier, C; Jin, JG; Daniel, JL; Smith, JB; Kunapuli, SP
      The P2Y1 receptor mediates ADP-induced p38 kinase-activating factor generation in human platelets

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    48. Malmsjo, M; Adner, M; Harden, TK; Pendergast, W; Edvinsson, L; Erlinge, D
      The stable pyrimidines UDP beta S and UTP gamma S discriminate between theP2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery

      BRITISH JOURNAL OF PHARMACOLOGY
    49. Mahaut-Smith, MP; Ennion, SJ; Rolf, MG; Evans, RJ
      ADP is not an agonist at P2X(1) receptors: evidence for separate receptorsstimulated by ATP and ADP on human platelets

      BRITISH JOURNAL OF PHARMACOLOGY
    50. Filippov, AK; Brown, DA; Barnard, EA
      The P2Y(1) receptor closes the N-type Ca2+ channel in neurones, with both adenosine triphosphates and diphosphates as potent agonists

      BRITISH JOURNAL OF PHARMACOLOGY
    51. Lenz, G; Gottfried, C; Luo, ZJ; Avruch, J; Rodnight, R; Nie, WJ; Kang, Y; Neary, JT
      P-2Y purinoceptor subtypes recruit different Mek activators in astrocytes

      BRITISH JOURNAL OF PHARMACOLOGY
    52. Storey, RF; Sanderson, HM; White, AE; May, JA; Cameron, KE; Heptinstall, S
      The central role of the P-2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity

      BRITISH JOURNAL OF HAEMATOLOGY
    53. Ohlmann, P; Eckly, A; Freund, M; Cazenave, JP; Offermanns, S; Gachet, C
      ADP induces partial platelet aggregation without shape change and potentiates collagen-induced aggregation in the absence of G alpha q

      BLOOD
    54. Gratacap, MP; Herault, JP; Viala, C; Ragab, A; Savi, P; Herbert, JM; Chap, H; Plantavid, M; Payrastre, B
      Fc gamma RIIA requires a Gi-dependent pathway for an efficient stimulationof phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation

      BLOOD
    55. Sak, K; Raidaru, G; Webb, TE; Jarv, J
      Phosphate-substituted ATP analogs are antagonists at human P2Y(1) purinoceptors

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    56. Cattaneo, M; Gachet, C
      ADP receptors and clinical bleeding disorders

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    57. Fabre, JE; Nguyen, MT; Latour, A; Keifer, JA; Audoly, LP; Coffman, TM; Koller, BH
      Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y(1)-deficient mice

      NATURE MEDICINE
    58. Kim, YB; Jin, JG; Dangelmaier, C; Daniel, JL; Kunapuli, SP
      The P2Y1 receptor is essential for ADP-induced shape change and aggregation in mouse platelets

      PLATELETS
    59. Liu, QD; Sloan, S; Frojmovic, MM
      ATP does not affect fibrinogen binding to platelet GPIIbIIIa in systems free of signal transduction

      PLATELETS
    60. Weber, AA; Hohlfeld, T; Schror, K
      cAMP is an important messenger for ADP-induced platelet aggregation

      PLATELETS
    61. Koziak, K; Sevigny, J; Robson, SC; Siegel, JB; Kaczmarek, E
      Analysis of CD39/ATP diphosphohydrolase (ATPDase) expression in endothelial cells, platelets and leukocytes

      THROMBOSIS AND HAEMOSTASIS
    62. Daniel, JL; Dangelmaier, C; Jin, JG; Kim, YB; Kunapuli, SP
      Role of intracellular signaling events in ADP-induced platelet aggregation

      THROMBOSIS AND HAEMOSTASIS
    63. Schwarz, UR; Geiger, J; Walter, U; Eigenthaler, M
      Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets - Definition and detection of ticlopidine/clopidogrel effects

      THROMBOSIS AND HAEMOSTASIS
    64. Shattil, SJ
      Signaling through platelet integrin alpha IIb beta 3: Inside-out, outside-in, and sideways

      THROMBOSIS AND HAEMOSTASIS
    65. Jantzen, HM; Gousset, L; Bhaskar, V; Vincent, D; Tai, A; Reynolds, EE; Conley, PB
      Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation

      THROMBOSIS AND HAEMOSTASIS
    66. Yu, HX; Bianchi, B; Metzger, R; Lynch, KJ; Kowaluk, EA; Jawis, MF; van Biesen, T
      Lack of specificity of [S-35]-ATP gamma S and [S-35]-ADP beta S as radioligands for ionotropic and metabotropic P2 receptor binding

      DRUG DEVELOPMENT RESEARCH
    67. Jacobson, KA; Hoffmann, C; Kim, YC; Camaioni, E; Nandanan, E; Jang, SY; Guo, DP; Ji, XD; von Kugelgen, I; Moro, S; Ziganshin, AU; Rychkov, A; King, BF; Brown, SG; Wildman, SS; Burnstock, G; Boyer, JL; Mohanram, A; Harden, TK
      Molecular recognition in P2 receptors: Ligand development aided by molecular modeling and mutagenesis

      NUCLEOTIDES AND THEIR RECEPTORS IN THE NERVOUS SYSTEMS
    68. Major, DT; Halbfinger, E; Fischer, B
      Molecular recognition of modified adenine nucleotides by the P2Y(1)-receptor. 2. A computational approach

      JOURNAL OF MEDICINAL CHEMISTRY
    69. Fischer, B; Chulkin, A; Boyer, JL; Harden, KT; Gendron, FP; Beaudoin, AR; Chapal, J; Hillaire-Buys, D; Petit, P
      2-thioether 5 '-O-(1-thiotriphosphate)adenosine derivatives as new insulinsecretagogues acting through P2Y-receptors

      JOURNAL OF MEDICINAL CHEMISTRY
    70. Takano, S; Kimura, J; Matsuoka, I; Ono, T
      No requirement of P2X1 purinoceptors for platelet aggregation

      EUROPEAN JOURNAL OF PHARMACOLOGY
    71. Dol-Gleizes, F; Mares, AM; Savi, P; Herbert, JM
      Relaxant effect of 2-methyl-thio-adenosine diphosphate on rat thoracic aorta: effect of clopidogrel

      EUROPEAN JOURNAL OF PHARMACOLOGY
    72. Quinn, MJ; Fitzgerald, DJ
      Ticlopidine and clopidogrel

      CIRCULATION
    73. McMillan, MR; Burnstock, G; Haworth, SG
      Vasodilatation of intrapulmonary arteries to P2-receptor nucleotides in normal and pulmonary hypertensive newborn piglets

      BRITISH JOURNAL OF PHARMACOLOGY
    74. Anwar, Z; Albert, JL; Gubby, SE; Boyle, JP; Roberts, JA; Webb, TE; Boarder, MR
      Regulation of cyclic AMP by extracellular ATP in cultured brain capillary endothelial cells

      BRITISH JOURNAL OF PHARMACOLOGY
    75. Park, HS; Hourani, SMO
      Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adenosine 5 '-diphospbate (ADP) in human platelets

      BRITISH JOURNAL OF PHARMACOLOGY
    76. Trumel, C; Payrastre, B; Plantavid, M; Hechler, B; Viala, C; Presek, P; Martinson, EA; Cazenave, JP; Chap, H; Gachet, C
      A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase

      BLOOD
    77. WEBB TE; SIMON J; BARNARD EA
      REGIONAL DISTRIBUTION OF [S-35] 2'-DEOXY 5'-O-(1-THIO) ATP BINDING-SITES AND THE P2Y(1) MESSENGER-RNA WITHIN THE CHICK BRAIN

      Neuroscience
    78. Kunapuli, SP
      Molecular physiology of platelet ADP receptors

      DRUG DEVELOPMENT RESEARCH
    79. Park, HS; Tennant, JP; Waktolla, GF; Sarkardei, S; Kass, GEN; Hourani, SMO
      Effects of adenosine 3 '-phosphate 5 '-phosphosulfate on P2 receptors in platelets and smooth muscle preparations

      DRUG DEVELOPMENT RESEARCH
    80. SAVI P; BEAUVERGER P; LABOURET C; DELFAUD M; SALEL V; KAGHAD M; HERBERT JM
      ROLE OF P2Y1 PURINOCEPTOR IN ADP-INDUCED PLATELET ACTIVATION

      FEBS letters
    81. BOYER JL; MOHANRAM A; CAMAIONI E; JACOBSON KA; HARDEN TK
      COMPETITIVE AND SELECTIVE ANTAGONISM OF P2Y(1) RECEPTORS BY N-6-METHYL 2'-DEOXYADENOSINE 3',5'-BISPHOSPHATE

      British Journal of Pharmacology
    82. KUNAPULI SP
      MULTIPLE P2 RECEPTOR SUBTYPES ON PLATELETS - A NEW INTERPRETATION OF THEIR FUNCTION

      Trends in pharmacological sciences
    83. SCHACHTER JB; SROMEK SM; NICHOLAS RA; HARDEN TK
      HEK293 HUMAN EMBRYONIC KIDNEY-CELLS ENDOGENOUSLY EXPRESS THE P2Y(1) AND P2Y(2) RECEPTORS

      Neuropharmacology
    84. SIMON J; WEBB TE; BARNARD EA
      DISTRIBUTION OF [S-35]DATP-ALPHA-S BINDING SITES IN THE ADULT RAT NEURAXIS

      Neuropharmacology
    85. SCHACHTER JB; BOYER JL; LI Q; NICHOLAS RA; HARDEN TK
      FIDELITY IN FUNCTIONAL COUPLING OF THE RAT P2Y(1) RECEPTOR TO PHOSPHOLIPASE-C

      British Journal of Pharmacology
    86. SCHACHTER JB; HARDEN TK
      AN EXAMINATION OF DEOXYADENOSINE 5'(ALPHA-THIO)TRIPHOSPHATE AS A LIGAND TO DEFINE P2Y RECEPTORS AND ITS SELECTIVITY AS A LOW POTENCY PARTIAL AGONIST OF THE P2Y(1) RECEPTOR

      British Journal of Pharmacology


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Documento generato il 23/01/21 alle ore 07:07:01