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1. Hruban, RH; Iacobuzio-Donahue, C; Wilentz, RE; Goggins, M; Kern, SE
   Molecular pathology of pancreatic cancer
   CANCER JOURNAL
   
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2. Klein, AP; Hruban, RH; Brune, KA; Petersen, GM; Goggins, M
   Familial pancreatic cancer
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3. McArthur, JG; Qian, HS; Citron, D; Banik, GG; Lamphere, L; Gyuris, J; Tsui, L; George, SE
   p27-p16 chimera: A superior antiproliferative for the prevention of neointimal hyperplasia
   MOLECULAR THERAPY
   
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4. Dai, ZY; Lakshmanan, RR; Zhu, WG; Smiraglia, DJ; Rush, LJ; Fruhwald, MC; Brena, RM; Li, B; Wright, FA; Ross, P; Otterson, GA; Plass, C
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5. Nairn, RS; Kazianis, S; Della Coletta, L; Trono, D; Butler, AP; Walter, RB; Morizot, DC
   Genetic analysis of susceptibility to spontaneous and UV-induced carcinogenesis in Xiphophorus hybrid fish
   MARINE BIOTECHNOLOGY
   
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6. Fukushima, K; Ueno, Y; Yamagiwa, Y; Yamakawa, M; Iwasaki, T; Ishii, M; Toyota, T; Shimosegawa, T
   Correlation between p21(waf1) and p16(INK4 alpha) expression in hepatocellular carcinoma
   HEPATOLOGY RESEARCH
   
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7. Shintani, S; Nakahara, Y; Mihara, M; Ueyama, Y; Matsumura, T
   Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas
   ORAL ONCOLOGY
   
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8. Viswanathan, M; Tsuchida, N; Shanmugam, G
   Selective deletion of p14(ARF) exon 1 beta of the INK4a locus in oral squamous cell carcinomas of Indians
   ORAL ONCOLOGY
   
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9. Chang, KW; Lin, SC; Chao, SY; Kwan, PC; Chiu, CP; Wong, YK
   Establishment and characterization of an oral melanoma cell line (ME)
   ORAL ONCOLOGY
   
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10. Tanaka, N; Odajima, T; Mimura, M; Ogi, K; Dehari, H; Kimijima, Y; Kohama, G
    Expression of Rb, pRb2/p130, p53, and p16 proteins in malignant melanoma of oral mucosa
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11. Bleichert, A; Fiedler, W; Claussen, U; Ernst, G; Loncarevic, IF; Heller, A; Liehr, T; Kunert, C; Von Eggeling, F
    A long distance-PCR derived FISH probe detects a deletion between p15 and p16 in CML and T-ALL patients
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    
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12. Szyf, M
    The role of DNA methyltransferase 1 in growth control
    FRONTIERS IN BIOSCIENCE
    
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13. Sinkre, P; Perry, A; Cai, D; Raghavan, R; Watson, M; Wilson, K; Rogers, BB
    Deletion of the NF2 region in both meningioma and juxtaposed meningioangiomatosis: Case report supporting a neoplastic relationship
    PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
    
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14. Yaswen, P; Stampfer, MR
    Epigenetic changes accompanying human mammary epithelial cell immortalization
    JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    
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15. Murphy, ME
    The battle between tumor suppressors: Is gene therapy using p16(INK4a) more efficacious than p53 for treatment of ovarian carcinoma?
    CLINICAL CANCER RESEARCH
    
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16. Shapiro, GI; Supko, JG; Patterson, A; Lynch, C; Lucca, J; Zacarola, PF; Muzikansky, A; Wright, JJ; Lynch, TJ; Rollins, BJ
    A phase II trial of the cyclin-dependent kinase inhibitor flavopiridol in patients with previously untreated stage IV non-small cell lung cancer
    CLINICAL CANCER RESEARCH
    
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17. Stadler, WM; Steinberg, G; Yang, XM; Hagos, F; Turner, C; Olopade, OI
    Alterations of the 9p21 and 9q33 chromosomal bands in clinical bladder cancer specimens by fluorescence in situ hybridization
    CLINICAL CANCER RESEARCH
    
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18. Henshall, SM; Quinn, DI; Lee, CS; Head, DR; Golovsky, D; Brenner, PC; Delprado, W; Stricker, PD; Grygiel, JJ; Sutherland, RL
    Overexpression of the cell cycle inhibitor p16(INK4A) in high-grade prostatic intraepithelial neoplasia predicts early relapse in prostate cancer patients
    CLINICAL CANCER RESEARCH
    
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19. Becker, TM; Rizos, H; Kefford, RF; Mann, GJ
    Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding
    CLINICAL CANCER RESEARCH
    
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20. Lee, CT; Seol, JY; Park, KH; Yoo, CG; Kim, YW; Ahn, C; Song, YW; Han, SK; Han, JS; Kim, S; Lee, JS; Shim, YS
    Differential effects of adenovirus-p16 on bladder cancer cell lines can beovercome by the addition of butyrate
    CLINICAL CANCER RESEARCH
    
    C.T. Lee et al., "Differential effects of adenovirus-p16 on bladder cancer cell lines can beovercome by the addition of butyrate", CLIN CANC R, 7(1), 2001, pp. 210-214
21. Keating, JT; Ince, T; Crum, CP
    Surrogate biomarkers of HPV infection in cervical neoplasia screening and diagnosis
    ADVANCES IN ANATOMIC PATHOLOGY
    
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22. Auroy, S; Avril, MF; Chompret, A; Pham, D; Goldstein, AM; Bianchi-Scarra, G; Frebourg, T; Joly, P; Spatz, A; Rubino, C; Demenais, F; Bressac-de Paillerets, B
    Sporadic multiple primary melanoma cases: CDKN2A germline mutations with afounder effect
    GENES CHROMOSOMES & CANCER
    
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23. Caballero, OL; Cohen, D; Liu, Q; Esteller, M; Bonacum, J; White, P; Engles, J; Yochem, R; Herman, JG; Westra, WH; Lengauer, C; Sidransky, D; Jen, J
    Loss of chromosome arms 3p and 9p and inactivation of P16 (INK4a) in normal epithelium of patients with primary lung cancer
    GENES CHROMOSOMES & CANCER
    
    O.L. Caballero et al., "Loss of chromosome arms 3p and 9p and inactivation of P16 (INK4a) in normal epithelium of patients with primary lung cancer", GENE CHROM, 32(2), 2001, pp. 119-125
24. Pollock, PM; Stark, MS; Palmer, JM; Walters, MK; Aitken, JF; Martin, NG; Hayward, NK
    Mutation analysis of the CDKN2A promoter in Australian melanoma families
    GENES CHROMOSOMES & CANCER
    
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25. Petronzelli, F; Sollima, D; Coppola, G; Martini-Neri, ME; Neri, G; Genuardi, M
    CDKN2A germline splicing mutation affecting both P16(ink4) and P14(arf) RNA processing in a melanoma/neurofibroma kindred
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26. Dominguez, C; Silva, J; Silva, JM; Garcia, JM; Larrondo, FJ; Vargas, J; Sanfrutos, L; Provencio, M; Espana, P; Bonilla, F
    Different expression of P14ARF defines two groups of breast carcinomas in terms of TP73 expression and TP53 mutational status
    GENES CHROMOSOMES & CANCER
    
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27. Hashemi, J; Bendahl, PO; Sandberg, T; Platz, A; Linder, S; Stierner, U; Olsson, H; Ingvar, C; Hansson, J; Borg, A
    Haplotype analysis and age estimation of the 113insR CDKN2A founder mutation in Swedish melanoma families
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28. Testa, JR; Giordano, A
    SV40 and cell cycle perturbations in malignant mesothelioma
    SEMINARS IN CANCER BIOLOGY
    
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29. Tschan, MP; Vonlanthen, S; Cajot, JF; Peters, UR; Oppliger, E; Betticher, DC; Yarbrough, WG; Fey, MF; Tobler, A
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    LEUKEMIA & LYMPHOMA
    
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30. Hofmann, WK; Tsukasaki, K; Takeuchi, N; Takeuchi, S; Koeffler, HP
    Methylation analysis of cell cycle control genes in adult T-cell leukemia/lymphoma
    LEUKEMIA & LYMPHOMA
    
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31. Einsiedel, HGV; Taube, T; Beyermann, B; Dragon, S; Moricke, A; Kebelmann-Betzig, C; Kochling, J; Henze, G; Seeger, K
    Absence of mutations in the CDKN2 binding site of CDK4 in childhood acute lymphoblastic leukemia
    LEUKEMIA & LYMPHOMA
    
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32. Hogg, D
    Genetic predisposition to melanoma
    CURRENT PROBLEMS IN DERMATOLOGY-US
    
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33. Brown, I; Milner, BJ; Rooney, PH; Haites, NE
    Inactivation of the p16(INK4A) gene by methylation is not a frequent eventin sporadic ovarian carcinoma
    ONCOLOGY REPORTS
    
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34. Nascimento, PD; Maciel, CM; Kawamura, MT; Oliveira, JA; Teixeira, A; Carvalho, MDC; Alves, G
    Molecular analysis of CDKN2 (p16) in gliomas associated with clinical data
    ONCOLOGY REPORTS
    
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35. Takeuchi, H; Ozawa, S; Ando, N; Kitagawa, Y; Mukai, M; Ueda, M; Kitajima, M
    Further evidence that altered p16/CDKN2 gene expression is associated withlymph node metastasis in squamous cell carcinoma of the esophagus
    ONCOLOGY REPORTS
    
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36. Sun, CL; Yamato, T; Furukawa, T; Ohnishi, Y; Kijima, H; Horii, A
    Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines
    ONCOLOGY REPORTS
    
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37. Wong, IHN
    Methylation profiling of human cancers in blood: Molecular monitoring and prognostication (Review)
    INTERNATIONAL JOURNAL OF ONCOLOGY
    
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38. Park, YK; Cho, CH; Chi, SG; Han, CS; Ushigome, S; Unni, KK
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39. Kurakawa, E; Shimamoto, T; Utsumi, K; Hirano, T; Kato, H; Ohyashiki, K
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40. Duque, PM; Parada, C; Guinea, J; Sanchez-Prieto, R; Cajal, SRY
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    INTERNATIONAL JOURNAL OF ONCOLOGY
    
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41. Papp, T; Schipper, H; Pemsel, H; Bastrop, R; Muller, KM; Wiethege, T; Weiss, DG; Dopp, E; Schiffmann, D; Rahman, Q
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    INTERNATIONAL JOURNAL OF ONCOLOGY
    
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42. Nakamura, M; Watanabe, T; Klangby, U; Asker, C; Wiman, K; Yonekawa, Y; Kleihues, P; Ohgaki, H
    p14(ARF) Deletion and methylation in genetic pathways to glioblastomas
    BRAIN PATHOLOGY
    
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43. Choi, YL; Park, SH; Jang, JJ; Park, CK
    Expression of the G1-S modulators in hepatitis B virus-related hepatocellular carcinoma and dysplastic nodule: Association of cyclin D1 and p53 proteins with the progression of hepatocellular carcinoma
    JOURNAL OF KOREAN MEDICAL SCIENCE
    
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44. Yi, J; Wang, ZW; Cang, H; Chen, YY; Zhao, R; Yu, BM; Tang, XM
    p16 gene methylation in colorectal cancers associated with Duke's staging
    WORLD JOURNAL OF GASTROENTEROLOGY
    
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45. He, XS; Su, Q; Chen, ZC; He, XT; Long, ZF; Ling, H; Zhang, LR
    Expression, deleton and mutation of p16 gene in human gastric cancer
    WORLD JOURNAL OF GASTROENTEROLOGY
    
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46. Ghaneh, P; Greenhalf, W; Humphreys, M; Wilson, D; Zumstein, L; Lemoine, NR; Neoptolemos, JP
    Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo
    GENE THERAPY
    
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47. Harland, M; Mistry, S; Bishop, DT; Bishop, JAN
    A deep intronic mutation in CDKN2A is associated with disease in a subset of melanoma pedigrees
    HUMAN MOLECULAR GENETICS
    
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48. Vassilev, N; Vassileva, M; Fenice, M; Federici, F
    Immobilized cell technology applied in solubilization of insoluble inorganic (rock) phosphates and P plant acquisition
    BIORESOURCE TECHNOLOGY
    
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49. Labuhn, M; Jones, G; Speel, EJM; Maier, D; Zweifel, C; Gratzl, O; Van Meir, EG; Hegi, ME; Merlo, A
    Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas
    ONCOGENE
    
    M. Labuhn et al., "Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas", ONCOGENE, 20(9), 2001, pp. 1103-1109
50. Zhu, WG; Dai, ZY; Ding, HM; Srinivasan, K; Hall, J; Duan, WR; Villalona-Calero, MA; Plass, C; Otterson, GA
    Increased expression of unmethylated CDKN2D by 5-aza-2 '-deoxycytidine in human lung cancer cells
    ONCOGENE
    
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51. Piao, CQ; Zhao, YL; Hei, TK
    Analysis of p16 and p21(Cip1) expression in tumorigenic human bronchial epithelial cells induced by asbestos
    ONCOGENE
    
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52. Gilley, J; Fried, M
    One INK4 gene and no ARF at the Fugu equivalent of the human INK4A/ARF/INK4B tumour suppressor locus
    ONCOGENE
    
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53. Tannapfel, A; Busse, C; Weinans, L; Benicke, M; Katalinic, A; Geissler, F; Hauss, J; Wittekind, C
    INK4a-ARF alterations and p53 mutations in hepatocellular carcinomas
    ONCOGENE
    
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54. Deneen, B; Denny, CT
    Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation
    ONCOGENE
    
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55. Chaussade, L; Eymin, B; Brambilla, E; Gazzeri, S
    Expression of p15 and p15.5 products in neuroendocrine lung tumours: relationship with p15(INK4b) methylation status
    ONCOGENE
    
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56. Pavey, S; Russell, T; Gabrielli, B
    G2 phase cell cycle arrest in human skin following UV irradiation
    ONCOGENE
    
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57. Schmidt, M; Koller, R; Haviernik, P; Bies, J; Maciag, K; Wolff, L
    Deregulated c-Myb expression in murine myeloid leukemias prevents the up-regulation of p15(INK4b) normally associated with differentiation
    ONCOGENE
    
    M. Schmidt et al., "Deregulated c-Myb expression in murine myeloid leukemias prevents the up-regulation of p15(INK4b) normally associated with differentiation", ONCOGENE, 20(43), 2001, pp. 6205-6214
58. Rizos, H; Puig, S; Badenas, C; Malvehy, J; Darmanian, AP; Jimenez, L; Mila, M; Kefford, RF
    A melanoma-associated germline mutation in exon 1 beta inactivates p14ARF
    ONCOGENE
    
    H. Rizos et al., "A melanoma-associated germline mutation in exon 1 beta inactivates p14ARF", ONCOGENE, 20(39), 2001, pp. 5543-5547
59. Sayan, AE; Sayan, BS; Findikli, N; Ozturk, M
    Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells
    ONCOGENE
    
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60. Silva, J; Dominguez, G; Silva, JM; Garcia, JM; Gallego, I; Corbacho, C; Provencio, M; Espana, P; Bonilla, F
    Analysis of genetic and epigenetic processes that influence p14ARF expression in breast cancer
    ONCOGENE
    
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61. Takita, J; Yang, HW; Chen, YY; Hanada, R; Yamamoto, K; Teitz, T; Kidd, V; Hayashi, Y
    Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma
    ONCOGENE
    
    J. Takita et al., "Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma", ONCOGENE, 20(32), 2001, pp. 4424-4432
62. Ronchetti, D; Greco, A; Compasso, S; Colombo, G; Dell'Era, P; Otsuki, T; Lombardi, L; Neri, A
    Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations
    ONCOGENE
    
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63. Milde-Langosch, K; Riethdorf, S; Kraus-Poppinghaus, A; Riethdorf, L; Loning, T
    Expression of cyclin-dependent kinase inhibitors p16(MTS1), p21(WAF1), andp27(KIP1) in HPV-positive and HPV-negative cervical adenocarcinomas
    VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
    
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64. Ambrosch, P; Schlott, T; Hilmes, D; Ruschenburg, I
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65. Sorio, C; Bonora, A; Orlandini, S; Moore, PS; Capelli, P; Cristofori, P; Dal Negro, G; Marchiori, P; Gaviraghi, G; Falconi, M; Pederzoli, P; Zamboni, G; Scarpa, A
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66. Calbo, J; Marotta, M; Cascallo, M; Roig, JM; Gelpi, JL; Fueyo, J; Mazo, A
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67. Hanamura, I; Iida, S; Akano, Y; Hayami, Y; Kato, M; Miura, K; Harada, S; Banno, S; Wakita, A; Kiyoi, H; Naoe, T; Shimizu, S; Sonta, S; Nitta, M; Taniwaki, M; Ueda, R
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68. Xue, Q; Sano, T; Kashiwabara, K; Oyama, T; Nakajima, T
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69. Tsai, CH; Yang, CC; Chou, LSS; Chou, MY
    The correlation between alteration of p16 gene and clinical status in oralsquamous cell carcinoma
    JOURNAL OF ORAL PATHOLOGY & MEDICINE
    
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70. Chan, J; Robinson, ES; Atencio, J; Wang, ZQ; Kazianis, S; Della Coletta, L; Nairn, RS; McCarrey, JR
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71. Park, TJ; Kim, HS; Byun, KH; Jang, JJ; Lee, YS; Lim, IK
    Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: Induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A)exon 1 in hepatocellular carcinoma
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72. Poi, MJ; Yen, T; Li, J; Song, HJ; Lang, JC; Schuller, DE; Pearl, DK; Casto, BC; Tsai, MD; Weghorst, CM
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73. Krahn, G; Leiter, U; Udart, M; Kaskel, P; Peter, RU
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74. Geradts, J; Wilentz, RE; Roberts, H
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75. Ramirez, RD; Morales, CP; Herbert, BS; Rohde, JM; Passons, C; Shay, JW; Wright, WE
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76. Chaubert, P; Burri, N; Cousin, P; Shaw, P
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77. Soenen, V; Lepelley, P; Gyan, E; Preudhomme, C; Lai, JL; Bauters, F; Fenaux, P; Quesnel, B
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78. Nakamura, M; Sugita, K; Inukai, T; Goi, K; Miyamoto, N; Kagami, K; Okazaki-Koyama, T; Mori, T; Saito, M; Nakazawa, S
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79. Uchida, T; Kinoshita, T; Ohno, T; Ohashi, H; Nagai, H; Saito, H
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80. Lo, YMD
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    BIOMEDICINE & PHARMACOTHERAPY
    
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81. Asp, J; Inerot, S; Block, JA; Lindahl, A
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    JOURNAL OF ORTHOPAEDIC RESEARCH
    
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82. Andreyev, J; Cunningham, D
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83. Esteller, M; Gonzalez, S; Risques, RA; Marcuello, E; Mangues, R; Germa, JR; Herman, JG; Capella, G; Peinado, MA
    K-ras and p16 aberrations confer poor prognosis in human colorectal cancer
    JOURNAL OF CLINICAL ONCOLOGY
    
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84. Pantoja, C; Palmero, I; Serrano, M
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    EXPERIMENTAL GERONTOLOGY
    
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85. Nomdedeu, JF; Badell, I; Estivill, C; Carnicer, MJ; Sierra, J; Baiget, M
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    HAEMATOLOGICA
    
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86. Muscarella, P; Knobloch, TJ; Ulrich, AB; Casto, BC; Moniaux, N; Wittel, UA; Melvin, WS; Pour, PM; Song, HJ; Gold, B; Batra, SK; Weghorst, CM
    Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells
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87. Wang, M; Wei, J; Zhang, JL
    Replacement of the p16 gene in human ovarian cancer cells
    CHINESE MEDICAL JOURNAL
    
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88. Wang, CW; Lu, XH; Liu, GY; Dai, L; Xu, T; Chen, YJ; Gao, CS; Wen, XH; Qian, JM
    Detailed deletion mapping on chromosome region 9p21 in human periampullaryneoplasms
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89. Bai, JX; Zhu, XG; Zheng, XC; Wu, YJ
    Retroviral vector containing human p16 gene and its inhibitory effect on Bcap-37 breast cancer cells
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90. Xie, Y; Bin, LH; Yang, JB; Li, ZH; Yu, Y; Zhang, XH; Cao, L; Li, GY
    Molecular cloning and characterization of NAG-7: a novel gene downregulated in human nasopharyngeal carcinoma
    CHINESE MEDICAL JOURNAL
    
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91. Ma, JP; Zhan, WH; Peng, JS; He, YL; Zheng, ZQ; Cai, SR; Wang, L; Wang, JP
    Telomerase activity and homozygous deletions of the p16 gene in liver metastases of colorectal carcinoma
    CHINESE MEDICAL JOURNAL
    
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92. Baba, Y; Tsukuda, M; Mochimatsu, I; Furukawa, S; Kagata, H; Satake, K; Koshika, S; Nakatani, Y; Hara, M; Kato, Y; Nagashima, Y
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    CANCER DETECTION AND PREVENTION
    
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93. Tokunaga, H; Shariat, SF; Green, AE; Brown, RM; Zhou, JH; Benedict, WF; Lerner, SP
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    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
    
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94. Nguyen, CT; Gonzales, FA; Jones, PA
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95. Mizesko, MC; Grewe, C; Grabner, A; Miller, MS
    Alterations at the Ink4a locus in transplacentally induced murine lung tumors
    CANCER LETTERS
    
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96. Kim, YT; Kim, J; Jang, YH; Lee, WJ; Ryu, JK; Park, YK; Kim, SW; Kim, WH; Yoon, YB; Kim, CY
    Genetic alterations in gallbladder adenoma, dysplasia and carcinoma
    CANCER LETTERS
    
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97. Mamay, CL; Schauer, IE; Rice, PL; Dwyer-Nield, LD; You, M; Sclafani, RA; Malkinson, AM
    Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells
    CANCER LETTERS
    
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98. Shannon, BA; Iacopetta, BJ
    Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features
    CANCER LETTERS
    
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99. Cheung, TH; Yu, MMY; Lo, KWK; Yim, SF; Chung, TKH; Wong, YF
    Alteration of cyclin D1 and CDK4 gene in carcinoma of uterine cervix
    CANCER LETTERS
    
    T.H. Cheung et al., "Alteration of cyclin D1 and CDK4 gene in carcinoma of uterine cervix", CANCER LETT, 166(2), 2001, pp. 199-206
100. Nakahara, Y; Shintani, S; Mihara, M; Ueyama, Y; Matsumura, T
     High frequency of homozygous deletion and methylation of p16(INK4A) gene in oral squamous cell carcinomas
     CANCER LETTERS
     
     Y. Nakahara et al., "High frequency of homozygous deletion and methylation of p16(INK4A) gene in oral squamous cell carcinomas", CANCER LETT, 163(2), 2001, pp. 221-228