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La ricerca find articoli where soggetti phrase all words 'OUTER-MEMBRANE PROTEIN' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 1528 riferimenti
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    1. Dumler, JS; Barbet, AF; Bekker, CPJ; Dasch, GA; Palmer, GH; Ray, SC; Rikihisa, Y; Rurangirwa, FR
      Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia withAnaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila

      INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
    2. Bouyer, DH; Stenos, J; Crocquet-Valdes, P; Moron, CG; Popov, VL; Zavala-Velazquez, JE; Foil, LD; Stothard, DR; Azad, AF; Walker, DH
      Rickettsia felis: molecular characterization of a new member of the spotted fever group

      INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
    3. Bush, RM; Everett, KDE
      Molecular evolution of the Chlamydiaceae

      INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
    4. Bas, S; Muzzin, P; Fulpius, T; Buchs, N; Vischer, TL
      Indirect evidence of intra-articular immunoglobulin G synthesis in patients with Chlamydia trachomatis reactive arthritis

      RHEUMATOLOGY
    5. Cianciotto, NP
      Pathogenicity of Legionella pneumophila

      INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
    6. El Tahir, Y; Skurnik, M
      YadA, the multifaceted Yersinia adhesin

      INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
    7. Braun, V
      Iron uptake mechanisms and their regulation in pathogenic bacteria

      INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
    8. Klose, KE
      Regulation of virulence in Vibrio cholerae

      INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
    9. Penn, CW
      Surface components of Campylobacter and Helicobacter

      JOURNAL OF APPLIED MICROBIOLOGY
    10. Mahdi, OS; Kalayoglu, M; Byrne, GI
      Emerging strategies in the diagnosis, prevention and treatment of chlamydial infections

      EXPERT OPINION ON THERAPEUTIC PATENTS
    11. Snyder, LAS; Butcher, SA; Saunders, NJ
      Comparative whole-genome analyses reveal over 100 putative phase-variable genes in the pathogenic Neisseria spp.

      MICROBIOLOGY-SGM
    12. Santiviago, CA; Toro, CS; Bucarey, SA; Mora, GC
      A chromosomal region surrounding the ompD porin gene marks a genetic difference between Salmonella typhi and the majority of Salmonella serovars

      MICROBIOLOGY-SGM
    13. Kleivdal, H; Puntervoll, P; Jensen, HB
      Topological investigations of the FomA porin from Fusobacterium nucleatum and identification of the constriction loop L6

      MICROBIOLOGY-UK
    14. King, AJ; Berbers, G; van Oirschot, HFLM; Hoogerhout, P; Knipping, K; Mooi, FR
      Role of the polymorphic region 1 of the Bordetella pertussis protein pertactin in immunity

      MICROBIOLOGY-SGM
    15. Kubo, A; Stephens, RS
      Substrate-specific diffusion of select dicarboxylates through Chlamydia trachomatis PorB

      MICROBIOLOGY-SGM
    16. Echenique, JR; Dorsey, CW; Patrito, LC; Petroni, A; Tolmasky, ME; Actis, LA
      Acinetobacter baumannii has two genes encoding glutathione-dependent formaldehyde dehydrogenase: evidence for differential regulation in response to iron

      MICROBIOLOGY-SGM
    17. Mills, KHG
      Immunity to Bordetella pertussis

      MICROBES AND INFECTION
    18. Hsieh, YH; Bobo, LD; Quinn, TC; West, SK
      Determinants of trachoma endemicity using Chlamydia trachomatis ompA DNA sequencing

      MICROBES AND INFECTION
    19. Takourt, B; de Barbeyrac, B; Khyatti, M; Radouani, F; Bebear, C; Dessus-Babus, S; Bebear, C; Benslimane, A
      Direct genotyping and nucleotide sequence analysis of VS1 and VS2 of the Omp1 gene of Chlamydia trachomatis from Moroccan trachomatous specimens

      MICROBES AND INFECTION
    20. Peck, B; Ortkamp, M; Nau, U; Niederweis, M; Hundt, E; Knapp, B
      Characterization of four members of a multigene family encoding outer membrane proteins of Helicobacter pylori and their potential for vaccination

      MICROBES AND INFECTION
    21. Trust, TJ; Alm, RA; Pappo, J
      Helicobacter pylori: Today's treatment, and possible future treatment

      EUROPEAN JOURNAL OF SURGERY
    22. Mattoo, S; Foreman-Wykert, AK; Cotter, PA; Miller, JF
      Mechanisms of Bordetella pathogenesis

      FRONTIERS IN BIOSCIENCE
    23. Achtman, M; van der Ende, A; Zhu, PX; Koroleva, IS; Kusecek, B; Morelli, G; Schuurman, IGA; Brieske, N; Zurth, K; Kostyukova, NN; Platonov, AE
      Molecular epidemiology of serogroup a meningitis in Moscow, 1969-1997

      EMERGING INFECTIOUS DISEASES
    24. Yao, SY; Ljunggren-Rose, A; Stratton, CW; Mitchell, WM; Sriram, S
      Regulation by IFN-beta of inducible nitric oxide synthase and interleukin-12/p40 in murine macrophages cultured in the presence of Chlamydia pneumoniae antigens

      JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
    25. Lautenbach, E; Strom, BL; Bilker, WB; Patel, JB; Edelstein, PH; Fishman, NO
      Epidemiological investigation of fluoroquinolone resistance in infections due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae

      CLINICAL INFECTIOUS DISEASES
    26. Granoff, DM
      Assessing efficacy of Haemophilus influenzae type b combination vaccines

      CLINICAL INFECTIOUS DISEASES
    27. Rehling, P; Wiedemann, N; Pfanner, N; Truscott, KN
      The mitochondrial import machinery for preproteins

      CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
    28. Choi, TY; Kim, DA; Seo, YH
      Evaluation of serotyping using monoclonal antibodies and PCR-RFLP for Chlamydia trachomatis serotype identification

      JOURNAL OF KOREAN MEDICAL SCIENCE
    29. Diggle, MA; Edwards, GFS; Clarke, SC
      Developments in the diagnosis of meningococcal disease and the characterization of Neisseria meningitidis

      REVIEWS IN MEDICAL MICROBIOLOGY
    30. Vinetz, JM
      Leptospirosis

      CURRENT OPINION IN INFECTIOUS DISEASES
    31. Low, AS; MacKenzie, FM; Gould, IM; Booth, IR
      Protected environments allow parallel evolution of a bacterial pathogen ina patient subjected to long-term antibiotic therapy

      MOLECULAR MICROBIOLOGY
    32. Miller, VL; Beer, KB; Heusipp, G; Young, BM; Wachtel, MR
      Identification of regions of Ail required for the invasion and serum resistance phenotypes

      MOLECULAR MICROBIOLOGY
    33. Wexler, M; Yeoman, KH; Stevens, JB; de Luca, NG; Sawers, G; Johnston, AWB
      The Rhizobium leguminosarum tonB gene is required for the uptake of siderophore and haem as sources of iron

      MOLECULAR MICROBIOLOGY
    34. Benz, I; Schmidt, MA
      Glycosylation with heptose residues mediated by the aah gene product is essential for adherence of the AIDA-I adhesin

      MOLECULAR MICROBIOLOGY
    35. Rasmussen, M; Bjorck, L
      Unique regulation of SclB - a novel collagen-like surface protein of Streptococcus pyogenes

      MOLECULAR MICROBIOLOGY
    36. Wyllie, S; Raulston, JE
      Identifying regulators of transcription in an obligate intracellular pathogen: a metal-dependent repressor in Chlamydia trachomatis

      MOLECULAR MICROBIOLOGY
    37. Richardson, AR; Stojiljkovic, I
      Mismatch repair and the regulation of phase variation in Neisseria meningitidis

      MOLECULAR MICROBIOLOGY
    38. Sandkvist, M
      Biology of type II secretion

      MOLECULAR MICROBIOLOGY
    39. Stahl, C; Kubetzko, S; Kaps, I; Seeber, S; Engelhardt, H; Niederweis, M
      MspA provides the main hydrophilic pathway through the cell wall of Mycobacterium smegmatis

      MOLECULAR MICROBIOLOGY
    40. Jin, SM; Joe, A; Lynett, J; Hani, EK; Sherman, P; Chan, VL
      JlpA, a novel surface-exposed lipoprotein specific to Campylobacter jejuni, mediates adherence to host epithelial cells

      MOLECULAR MICROBIOLOGY
    41. Hill, DJ; Toleman, MA; Evans, DJ; Villullas, S; van Alphen, L; Virji, M
      The variable P5 proteins of typeable and non-typeable Haemophilus influenzae target human CEACAM1

      MOLECULAR MICROBIOLOGY
    42. Genco, CA; Dixon, DW
      Emerging strategies in microbial haem capture

      MOLECULAR MICROBIOLOGY
    43. Huang, YH; Chang, HC; Chang, TC
      Development of a latex agglutination test for rapid identification of Escherichia coli

      EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
    44. Galdiero, M; Vitiello, M; D'Isanto, M; Peluso, L; Galdiero, M
      Induction of tyrosine phosphorylated proteins in THP-1 cells by Salmonellatyphimurium, Pasteurella haemolytica and Haemophilus influenzae porins

      FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
    45. Wang, FI; Shieh, H; Liao, YK
      Prevalence of Chlamydophila abortus infection in domesticated ruminants inTaiwan

      JOURNAL OF VETERINARY MEDICAL SCIENCE
    46. Prince, SM; Feron, C; Janssens, D; Lobet, Y; Achtman, M; Kusecek, B; Bullough, PA; Derrick, JP
      Expression, refolding and crystallization of the OpcA invasin from Neisseria meningitidis

      ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    47. Abergel, C; Walburger, A; Chenivesse, S; Lazdunski, C
      Crystallization and preliminary crystallographic study of the peptidoglycan-associated lipoprotein from Escherichia coli

      ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
    48. Imatani, T; Kato, T; Okuda, K
      Production of inflammatory cytokines by human gingival fibroblasts stimulated by cell-surface preparations of Porphyromonas gingivalis

      ORAL MICROBIOLOGY AND IMMUNOLOGY
    49. Oyaizu, K; Ohyama, H; Nishimura, F; Kurihara, H; Matsushita, S; Maeda, H; Kokeguchi, S; Hongyo, H; Takashiba, S; Murayama, Y
      Identification and characterization of B-cell epitopes of a 53-kDa outer membrane protein from Porphyromonas gingivalis

      ORAL MICROBIOLOGY AND IMMUNOLOGY
    50. Bradford, PA
      Extended-spectrum beta-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat

      CLINICAL MICROBIOLOGY REVIEWS
    51. Sethi, S; Murphy, TF
      Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review

      CLINICAL MICROBIOLOGY REVIEWS
    52. Rosenstein, NE; Fischer, M; Tappero, JW
      Meningococcal vaccines

      INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
    53. Lee, VT; Schneewind, O
      Protein secretion and the pathogenesis of bacterial infections

      GENES & DEVELOPMENT
    54. Carmenate, T; Mesa, C; Menendez, T; Falcon, V; Musacchio, A
      Recombinant Opc protein from Neisseria meningitidis reconstituted into liposomes elicits opsonic antibodies following immunization

      BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
    55. Duthy, TG; Manning, PA; Heuzenroeder, MW
      Characterization of the CsfC and CsfD proteins involved in the biogenesis of CS5 pili from enterotoxigenic Escherichia coli

      MICROBIAL PATHOGENESIS
    56. Toropainen, M; Saarinen, L; van der Ley, P; Kuipers, B; Kayhty, H
      Murine monoclonal antibodies to PorA of Neisseria meningitidis show reduced protective activity in vivo against B : 15 : P1.7,16 subtype variants in an infant rat infection model

      MICROBIAL PATHOGENESIS
    57. Volp, K; Mathews, S; Timms, P; Hafner, LM
      Peptide immunization of guinea pigs against Chlamydia psittaci (GPIC agent) infection induces good vaginal secretion antibody response, in vitro neutralization and partial protection against live challenge

      IMMUNOLOGY AND CELL BIOLOGY
    58. Corbeil, LB; BonDurant, RH
      Immunity to bovine reproductive infections

      VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE
    59. Dhungyel, OP; Whittington, RJ; Ghimire, SC; Egerton, JR
      Pilus ELISA and an anamnestic test for the diagnosis of virulent ovine footrot and its application in a disease control program in Nepal

      VETERINARY MICROBIOLOGY
    60. Buendia, AJ; Cuello, F; Del Rio, L; Gallego, MC; Caro, MR; Salinas, J
      Field evaluation of a new commercially available ELISA based on a recombinant antigen for diagnosing Chlamydophila abortus (Chlamydia psittaci serotype 1) infection

      VETERINARY MICROBIOLOGY
    61. Robb, CW; Orihuela, CJ; Ekkelenkamp, MB; Niesel, DW
      Identification and characterization of an in vivo regulated D15/Oma87 homologue in Shigella flexneri using differential display polymerase chain reaction

      GENE
    62. Reichelt, M; von Specht, BU; Hahn, HP
      The Caulobacter crescentus outer membrane protein Omp58 (RsaF) is not required for paracrystalline S-layer secretion

      FEMS MICROBIOLOGY LETTERS
    63. Troncoso, G; Sanchez, S; Kolberg, J; Rosenqvist, E; Veiga, M; Ferreiros, CM; Criado, MT
      Analysis of the expression of the putatively virulence-associated neisserial protein RmpM (class 4) in commensal Neisseria and Moraxella catarrhalis strains

      FEMS MICROBIOLOGY LETTERS
    64. Achouak, W; Heulin, T; Pages, JM
      Multiple facets of bacterial porins

      FEMS MICROBIOLOGY LETTERS
    65. Longbottom, D; Psarrou, E; Livingstone, M; Vretou, E
      Diagnosis of ovine enzootic abortion using an indirect ELISA (rOMP91B iELISA) based on a recombinant protein fragment of the polymorphic outer membrane protein POMP91B of Chlamydophila abortus

      FEMS MICROBIOLOGY LETTERS
    66. Faden, H
      The microbiologic and immunologic basis for recurrent otitis media in children

      EUROPEAN JOURNAL OF PEDIATRICS
    67. Navarro, F; Perez-Trallero, E; Marimon, JM; Aliaga, R; Gomariz, M; Mirelis, B
      CMY-2-producing Salmonella enterica, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus mirabilis and Escherichia coli strains isolated in Spain (October 1999-December 2000)

      Journal of antimicrobial chemotherapy
    68. Hoffer, SM; van Uden, N; Tommassen, J
      Expression of the pho regulon interferes with induction of the uhpT gene in Escherichia coli K-12

      ARCHIVES OF MICROBIOLOGY
    69. de Kleijn, E; van Eijndhoven, L; Vermont, C; Kuipers, B; van Dijken, H; Rumke, H; de Groot, R; van Alphen, L; van den Dobbelsteen, G
      Serum bactericidal activity and isotype distribution of antibodies in toddlers and schoolchildren after vaccination with RIVM hexavalent PorA vesiclevaccine

      VACCINE
    70. Ross, BC; Czajkowski, L; Hocking, D; Margetts, M; Webb, E; Rothel, L; Patterson, M; Agius, C; Camuglia, S; Reynolds, E; Littlejohn, T; Gaeta, B; Ng, A; Kuczek, ES; Mattick, JS; Gearing, D; Barr, IG
      Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis

      VACCINE
    71. Whittum-Hudson, JA; Rudy, D; Gerard, H; Vora, G; Davis, E; Haller, PK; Prattis, SM; Hudson, AP; Saltzman, WM; Stuart, ES
      The anti-idiotypic antibody to chlamydial glycolipid exoantigen (GLXA) protects mice against genital infection with a human biovar of Chlamydia trachomatis

      VACCINE
    72. Siegrist, CA
      Neonatal and early life vaccinology

      VACCINE
    73. Niebla, O; Alvarez, A; Martin, A; Rodriguez, A; Delgado, M; Falcon, V; Guillen, G
      Immunogenicity of recombinant class 1 protein from Neisseria meningitidis refolded into phospholipid vesicles and detergent

      VACCINE
    74. Kyd, JM; Foxwell, AR; Cripps, AW
      Mucosal immunity in the lung and upper airway

      VACCINE
    75. Pollard, AJ; Frasch, C
      Development of natural immunity to Neisseria meningitidis

      VACCINE
    76. Schembri, MA; Klemm, P
      Coordinate gene regulation by fimbriae-induced signal transduction

      EMBO JOURNAL
    77. Xia, PY; Feng, P; Zhong, L; Lu, XJ; Lei, BJ
      Accumulation of ofloxacin and tosufloxacin in fluoroquinolone resistant E coli

      ACTA PHARMACOLOGICA SINICA
    78. Sykes, JE
      Feline upper respiratory tract pathogens: Chlamydophila felis

      COMPENDIUM ON CONTINUING EDUCATION FOR THE PRACTICING VETERINARIAN
    79. Vandahl, BB; Gevaert, K; Demol, H; Hoorelbeke, B; Holm, A; Vandekerckhove, J; Christiansen, G; Birkelund, S
      Time-dependent expression and processing of a hypothetical protein of possible importance for regulation of the Chlamydia pneumoniae developmental cycle

      ELECTROPHORESIS
    80. Smith, AM; Guzman, CA; Walker, MJ
      The virulence factors of Bordetella pertussis: a matter of control

      FEMS MICROBIOLOGY REVIEWS
    81. Epp, SF; Pechere, JC; Kok, M
      Raising antibodies against OprD, an outer membrane protein of Pseudomonas aeruginosa using translational fusions to MalE

      JOURNAL OF MICROBIOLOGICAL METHODS
    82. Menendez, T; De Haz, I; Delgado, M; Garay, H; Martin, A; Vispo, NS
      Immunisation with phage-displayed variable region 2 from meningococcal PorA outer membrane protein induces bactericidal antibodies against Neisseria meningitidis

      IMMUNOLOGY LETTERS
    83. Fox, AJ
      Nucleic acid technologies and meningococcal infection

      JOURNAL OF INFECTION
    84. Bauer, MF; Neupert, W
      Import of proteins into mitochondria: A novel pathomechanism for progressive neurodegeneration

      JOURNAL OF INHERITED METABOLIC DISEASE
    85. Entrican, G; Buxton, D; Longbottom, D
      Chlamydial infection in sheep: immune control versus fetal pathology

      JOURNAL OF THE ROYAL SOCIETY OF MEDICINE
    86. Rivera, ING; Chun, J; Huq, A; Sack, RB; Colwell, RR
      Genotypes associated with virulence in environmental isolates of Vibrio cholerae

      APPLIED AND ENVIRONMENTAL MICROBIOLOGY
    87. Flannery, B; Costa, D; Carvalho, FP; Guerreiro, H; Matsunaga, J; Da Silva, ED; Ferreira, AGP; Riley, LW; Reis, MG; Haake, DA; Ko, AI
      Evaluation of recombinant Leptospira antigen-based enzyme-linked immunosorbent assays for the serodiagnosis of leptospirosis

      JOURNAL OF CLINICAL MICROBIOLOGY
    88. Sacchi, CT; Lemos, APS; Popovic, T; de Morais, JC; Whitney, AM; Melles, CEA; Brondi, LMG; Monteiro, LMC; Paiva, MV; Solari, CA; Mayer, LW
      Serosubtypes and PorA types of Neisseria meningitidis serogroup B isolatedin Brazil during 1997-1998: Overview and implications for vaccine development

      JOURNAL OF CLINICAL MICROBIOLOGY
    89. Stothard, DR
      Use of a reverse dot blot procedure to identify the presence of multiple serovars in Chlamydia trachomatis urogenital infection

      JOURNAL OF CLINICAL MICROBIOLOGY
    90. Dubois, V; Arpin, C; Melon, M; Melon, B; Andre, C; Frigo, CC; Quentin, C
      Nosocomial outbreak due to a multiresistant strain of Pseudomonas aeruginosa P12: Efficacy of cefepime-amikacin therapy and analysis of beta-lactam resistance

      JOURNAL OF CLINICAL MICROBIOLOGY
    91. Neuwirth, C; Siebor, E; Pechinot, A; Duez, JM; Pruneaux, M; Garel, F; Kazmierczak, A; Labia, R
      Evidence of in vivo transfer of a plasmid encoding the extended-spectrum beta-lactamase TEM-24 and other resistance factors among different members of the family Enterobacteriaceae

      JOURNAL OF CLINICAL MICROBIOLOGY
    92. Tzanakaki, G; Urwin, R; Musilek, M; Kriz, P; Kremastinou, J; Pangalis, A; Blackwell, CC; Maiden, MCJ
      Phenotypic and genotypic approaches to characterization of isolates of Neisseria meningitidis from patients and their close family contacts

      JOURNAL OF CLINICAL MICROBIOLOGY
    93. Jurstrand, M; Falk, L; Fredlund, H; Lindberg, M; Olcen, P; Andersson, S; Persson, K; Albert, J; Backman, A
      Characterization of Chlamydia trachomatis omp1 genotypes among sexually transmitted disease patients in Sweden

      JOURNAL OF CLINICAL MICROBIOLOGY
    94. Ryan, MT; Voos, W; Pfanner, N
      Assaying protein import into mitochondria

      METHODS IN CELL BIOLOGY, VOL 65
    95. Waterer, GW; Wunderink, RG
      Increasing threat of Gram-negative bacteria

      CRITICAL CARE MEDICINE
    96. Nadjar, D; Labia, R; Cerceau, C; Bizet, C; Philippon, A; Arlet, G
      Molecular characterization of chromosomal class C beta-lactamase and its regulatory gene in Ochrobactrum anthropi

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    97. Yigit, H; Queenan, AM; Anderson, GJ; Domenech-Sanchez, A; Biddle, JW; Steward, CD; Alberti, S; Bush, K; Tenover, FC
      Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    98. Dreses-Werringloer, U; Padubrin, I; Zeidler, H; Kohler, L
      Effects of azithromycin and rifampin on Chlamydia trachomatis infection invitro

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    99. Feil, EJ; Spratt, BG
      Recombination and the population structures of bacterial pathogens

      ANNUAL REVIEW OF MICROBIOLOGY
    100. Laroucau, K; Boumedine, KS; Rodolakis, A
      Amplified fragment length polymorphism differentiation between the vaccinestrain Chlamydia psittaci 1B and wild field strains

      VETERINARY RECORD


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Documento generato il 17/01/21 alle ore 14:35:39