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Nitrogen-containing bisphosphonates induce apoptosis of Caco-2 cells in vitro by inhibiting the mevalonate pathway: A model of bisphosphonate-inducedgastrointestinal toxicity
BONE
Bisphosphonates: mechanisms of action
EXPERT OPINION ON THERAPEUTIC PATENTS
Expression of CD31, Met/hepatocyte growth factor receptor and bone morphogenetic protein in bone metastasis of osteosarcoma
PATHOLOGY INTERNATIONAL
Interleukin-1 beta stimulates transendothelial mobilization of human peripheral blood mononuclear cells with a potential to differentiate into osteoclasts in the presence of osteoblasts
ENDOCRINE JOURNAL
Humoral hypercalcemia of malignancy in female F344 rats implanted with a transplantable rat pulmonary carcinoma line (IP)
JOURNAL OF VETERINARY MEDICAL SCIENCE
Indapamide, a thiazide-like diuretic, decreases bone resorption in vitro
JOURNAL OF BONE AND MINERAL RESEARCH
The skeletal structure of insulin-like growth factor I-deficient mice
JOURNAL OF BONE AND MINERAL RESEARCH
Immunohistochemical localization of components of the insulin-like growth factor-system in human deciduous teeth
CONNECTIVE TISSUE RESEARCH
Statins and bone: Myth or reality?
CALCIFIED TISSUE INTERNATIONAL
Stimulative effect of cadmium on prostaglandin E-2 production in primary mouse osteoblastic cells
CALCIFIED TISSUE INTERNATIONAL
Substance P activates osteoclast formation and osteoclastic bone resorption through the neurokinin-1 receptor
ACTA HISTOCHEMICA ET CYTOCHEMICA
Interferon-gamma down-regulates gene expression of cathepsin K in osteoclasts and inhibits osteoclast formation
JOURNAL OF DENTAL RESEARCH
Osteolysis and cancer
JOURNAL OF CLINICAL INVESTIGATION
In vitro effects of low-intensity ultrasound stimulation on the bone cells
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor
FEBS LETTERS
PGE(2) is essential for gap junction-mediated intercellular communication between osteocyte-like MLO-Y4 cells in response to mechanical strain
ENDOCRINOLOGY
Aberrant growth plate development in VDR/RXR gamma double null mutant mice
ENDOCRINOLOGY
Bisphosphonate treatment inhibits the growth of prostate cancer cells
CANCER RESEARCH
Statins: new therapeutic possibilities for osteoporosis?
DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT
Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D-3 and RANKL
BONE
Ovariectomy does not induce osteopenia through interleukin-6 in rhesus monkeys (Macaca mulatta)
BONE
Correlation of estradiol, parathyroid hormone, interleukin-6, and soluble interleukin-6 receptor during the normal menstrual cycle
BONE
Mechanisms of action of bisphosphonates on tumor cells and prospects for use in the treatment of malignant osteolysis
JOINT BONE SPINE
Interleukin-18 stimulates HIV-1 replication in a T-cell line
EUROPEAN CYTOKINE NETWORK
In vitro studies of insulin-like growth factor I and bone
GROWTH HORMONE & IGF RESEARCH
Interleukin 18 - Interferon gamma inducing factor - A novel player in tumour immunotherapy?
CYTOKINE
Induction of the activity of the histamine-forming enzyme, histidine decarboxylase, in mice by IL-18 and by IL-18 plus IL-12
INFLAMMATION RESEARCH
The role of IL-18 in innate immunity
CURRENT OPINION IN IMMUNOLOGY
Cytokines and bone loss in a 5-year longitudinal study - Hormone replacement therapy suppresses serum soluble interleukin-6 receptor and increases interleukin-1-receptor antagonist: The Danish Osteoporosis Prevention Study
JOURNAL OF BONE AND MINERAL RESEARCH
Stimulatory effect of insulin-like growth factor binding protein-5 on mouse osteoclast formation and osteoclastic bone-resorbing activity
JOURNAL OF BONE AND MINERAL RESEARCH
Concentration of bisphosphonate (incadronate) in callus area and its effects on fracture healing in rats
JOURNAL OF BONE AND MINERAL RESEARCH
Bone resorption in multiple myeloma
PRESSE MEDICALE
Annexin II is the membrane receptor that mediates the rapid actions of 1 alpha,25-dihydroxyvitamin D-3
JOURNAL OF CELLULAR BIOCHEMISTRY
Treatment of established collagen induced arthritis with prostaglandin E-1incorporated in lipid microspheres
JOURNAL OF RHEUMATOLOGY
Cytochemical and ultrastructural examination of apoptotic odontoclasts induced by bisphosphonate administration
CELL AND TISSUE RESEARCH
Bisphosphonates - Mechanisms of action in multiple myeloma
ACTA ONCOLOGICA
Disaccharide-trehalose inhibits bone resorption in ovariectomized mice
NUTRITION RESEARCH
cAMP attenuates interleukin-1-stimulated macrophage colony-stimulating factor (M-CSF) expression
BIOCHEMICAL JOURNAL
Inhibitory effect of NF-kappa B on 1,25-dihydroxyvitamin D-3 and retinoid X receptor function
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Role of persistent amenorrhea in bone mineral metabolism of young hemodialyzed women
KIDNEY INTERNATIONAL
Therapeutic approaches to bone diseases
SCIENCE
Bisphosphonates directly regulate cell proliferation, differentiation, andgene expression in human osteoblasts
CANCER RESEARCH
Trabecular bone turnover, bone marrow cell development, and gene expression of bone matrix proteins after low calcium feeding in rats
BONE
Chemical sympathectomy impairs bone resorption in rats: A role for the sympathetic system on bone metabolism
BONE
Involvement of fibroblast growth factor-2 in joint destruction of rheumatoid arthritis patients
RHEUMATOLOGY
Mechanisms of action of bisphosphonates
REVUE DU RHUMATISME
Prostaglandins and bone: physiology and pathophysiology
OSTEOARTHRITIS AND CARTILAGE
The effect of kampo formulae on bone resorption in vitro and in vivo. II. Detailed study of berberine
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Insulin-like growth factor-I (IGF-I) and IGF-I receptor (TGF-IR) immunoreactivity in normal and osteopetrotic (toothless, tl/tl) rat tibia
GROWTH FACTORS
Mechanism in inhibitory effects of vitamin K-2 on osteoclastic bone resorption: In vivo study in osteopetrotic (op/op) mice
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
Inhibition by interleukin 18 of osteolytic bone metastasis by human breastcancer cells
ANTICANCER RESEARCH
Insulin-like growth factor I rapidly enhances acid efflux from osteoblastic cells
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
The effect of sintered beta-dicalcium pyrophosphate particle size on newborn Wistar rat osteoblasts
ARTIFICIAL ORGANS
Serum levels of insulin-like growth factor I and the density, volume, and cross-sectional area of cortical bone in children
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
Role of NF kappa B in the regulation of macrophage colony stimulating factor by tumor necrosis factor-alpha in ST2 bone stromal cells
JOURNAL OF CELLULAR PHYSIOLOGY
Bone defect healing enhanced by ultrasound stimulation: An in vitro tissueculture model
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
Induction of apoptosis of monocyte-macrophage lineage cells by 5-S-GAD
FEBS LETTERS
Macrophage colony stimulating-factor transcripts are differentially regulated in rat bone-marrow by gender hormones
ENDOCRINOLOGY
Effects of vitamin D-3, 17 beta-estradiol, vasoactive intestinal peptide, and glutamate on electric coupling between rat osteoblast-like cells in vitro
BONE
CHANGES IN LOCATION AND NUMBER OF TARTRATE-RESISTANT ACID-PHOSPHATASE(TRAP)-POSITIVE CELLS DURING THE DEVELOPMENT OF TYPE-II COLLAGEN-INDUCED ARTHRITIS IN DBA 1J MICE/
Experimental animals
OSTEOBLASTIC CELLS REGULATE MI GENE-EXPRESSION IN CULTURED BONE-MARROW CELLS
International journal of hematology
SECRETION OF CSF-1 AND ITS INHIBITION IN RAT DENTAL FOLLICLE CELLS - IMPLICATIONS FOR TOOTH ERUPTION
European journal of oral sciences
ALENDRONATE INTERLEUKIN-1-BETA COTREATMENT INCREASES INTERLEUKIN-6 INBONE AND UMR-106 CELLS - DOSE DEPENDENCE AND RELATIONSHIP TO THE ANTIRESORPTIVE EFFECT OF ALENDRONATE/
Journal of bone and mineral research
STRUCTURALLY DIFFERENT BISPHOSPHONATES EXERT OPPOSING EFFECTS ON ALKALINE-PHOSPHATASE AND MINERALIZATION IN MARROW OSTEOPROGENITORS
Journal of cellular biochemistry
EFFECT OF MONOCLONAL ANTI-HUMAN GP130 ANTIBODY (GPX7) ON BONE TURNOVER IN NORMAL AND OVARIECTOMIZED RATS
Calcified tissue international
Modulation of bone morphogenetic protein-2 and bone morphogenetic protein-4 gene expression in osteoblastic cell lines
CELLULAR AND MOLECULAR BIOLOGY
EFFECTS OF CORTISOL ON THE EXPRESSION OF INTERLEUKIN-6 AND INTERLEUKIN-1-BETA IN HUMAN OSTEOBLAST-LIKE CELLS
Journal of Endocrinology
LOSS OF ESTROGEN UP-REGULATES OSTEOBLASTOGENESIS IN THE MURINE BONE-MARROW - EVIDENCE FOR AUTONOMY FROM FACTORS RELEASED DURING BONE-RESORPTION
The Journal of clinical investigation
OSTEOPROTEGERIN MESSENGER-RNA IS INCREASED BY INTERLEUKIN-1-ALPHA IN THE HUMAN OSTEOSARCOMA CELL-LINE MG-63 AND IN HUMAN OSTEOBLAST-LIKE CELLS
Biochemical and biophysical research communications (Print)
ROLES OF IGF-SYSTEM IN BONE METABOLISM
Nippon Nogei Kagakukaishi
AROMATASE CYTOCHROME-P450 TRANSCRIPTS ARE DETECTED IN FRACTURED HUMANBONE BUT NOT IN NORMAL SKELETAL TISSUE
Bone
EFFECT OF ALENDRONATE TREATMENT ON THE OSTEOCLASTOGENIC POTENTIAL OF BONE-MARROW CELLS IN MICE
Bone
THE PREVENTION OR TREATMENT OF AGE-RELATED OSTEOPOROSIS IN THE ELDERLY BY SYSTEMIC RECOMBINANT GROWTH-FACTOR THERAPY (RHIGF-I OR RHTGF-BETA) - A PERSPECTIVE
Journal of internal medicine
THE FUNCTIONAL MATRIX HYPOTHESIS REVISITED .2. THE ROLE OF AN OSSEOUSCONNECTED CELLULAR NETWORK
American journal of orthodontics and dentofacial orthopedics
CHARACTERIZATION OF ZINC EFFECT TO INHIBIT OSTEOCLAST-LIKE CELL-FORMATION IN MOUSE MARROW CULTURE - INTERACTION WITH DEXAMETHASONE
Molecular and cellular biochemistry
ENDOTHELIN STIMULATES OSTEOBLASTIC PRODUCTION OF IL-6 BUT NOT MACROPHAGE-COLONY-STIMULATING FACTOR
American journal of physiology: endocrinology and metabolism
AN ULTRASTRUCTURAL-STUDY OF CELL-CELL CONTACT BETWEEN MOUSE SPLEEN-CELLS AND CALVARIA-DERIVED OSTEOBLASTIC CELLS IN A COCULTURE SYSTEM FOR OSTEOCLAST FORMATION
Acta histochemica et cytochemica
INTERLEUKIN-6 WITH ITS SOLUBLE RECEPTOR ENHANCES THE EXPRESSION OF INSULIN-LIKE GROWTH-FACTOR-I IN OSTEOBLASTS
Endocrinology
ALENDRONATE INHIBITION OF PROTEIN-TYROSINE-PHOSPHATASE-MEG1
Biochemical pharmacology
ENHANCEMENT BY CONDITIONED MEDIUM OF STRETCHED CALVARIAL BONE-CELLS OF THE OSTEOCLAST-LIKE CELL-FORMATION INDUCED BY PARATHYROID-HORMONE INMOUSE BONE-MARROW CULTURES
Archives of oral biology
PCR PHENOTYPING OF CYTOKINES, GROWTH-FACTORS AND THEIR RECEPTORS AND BONE-MATRIX PROTEINS IN HUMAN OSTEOBLAST-LIKE CELL-LINES
Bone
HERBIMYCIN-A, A TYROSINE KINASE INHIBITOR, IMPAIRS HYPERCALCEMIA ASSOCIATED WITH A HUMAN SQUAMOUS CANCER PRODUCING INTERLEUKIN-6 IN NUDE-MICE
Journal of bone and mineral research
RECENT DEVELOPMENTS IN THE UNDERSTANDING OF THE PATHOPHYSIOLOGY OF OSTEOPETROSIS
European journal of endocrinology
ZINC-COMPOUNDS INHIBIT OSTEOCLAST-LIKE CELL-FORMATION AT THE EARLIER STAGE OF RAT MARROW CULTURE BUT NOT OSTEOCLAST FUNCTION
Molecular and cellular biochemistry
OSTEOLYTIC PROPERTIES OF THE SYNOVIAL-LIKE TISSUE FROM ASEPTICALLY FAILED JOINT PROSTHESES
British journal of rheumatology
OSTEOCLAST DIFFERENTIATION ANTIGEN
Histology and histopathology
BIODEGRADATION OF SYNTHETIC BIPHASIC CALCIUM-PHOSPHATE BY HUMAN MONOCYTES IN-VITRO - A MORPHOLOGICAL-STUDY
Biomaterials
IL-13 AND IL-4 INHIBIT BONE-RESORPTION BY SUPPRESSING CYCLOOXYGENASE-2-DEPENDENT PROSTAGLANDIN SYNTHESIS IN OSTEOBLASTS
The Journal of immunology
LINKAGE OF DECREASED BONE MASS WITH IMPAIRED OSTEOBLASTOGENESIS IN A MURINE MODEL OF ACCELERATED SENESCENCE
The Journal of clinical investigation
GROWTH-HORMONE INCREASES INTERLEUKIN-6 PRODUCED BY HUMAN OSTEOBLAST-LIKE CELLS
The Journal of clinical endocrinology and metabolism
EFFECTS OF SHORT-TERM RECOMBINANT HUMAN INSULIN-LIKE GROWTH-FACTOR-I ADMINISTRATION ON BONE TURNOVER IN OSTEOPENIC WOMEN WITH ANOREXIA-NERVOSA
The Journal of clinical endocrinology and metabolism
THE BIOCHEMICAL PATHWAY MEDIATING THE PROLIFERATIVE RESPONSE OF BONE-CELLS TO A MECHANICAL STIMULUS
Journal of bone and joint surgery. American volume
IDENTIFICATION OF A NOVEL BONE CALCIUM METABOLISM-REGULATING FACTOR IN PORCINE PANCREAS/
The Journal of biological chemistry
THE INHIBITORY EFFECT OF VITAMIN-K-2 (MENATETRENONE) ON BONE-RESORPTION MAY BE RELATED TO ITS SIDE-CHAIN
Bone
BIODEGRADATION OF SYNTHETIC BIPHASIC CALCIUM-PHOSPHATE AND BIOLOGICALCALCIFIED SUBSTRATUM BY CELLS OF HEMATOPOIETIC ORIGIN
Cells and materials
SIGNAL-TRANSDUCTION MECHANISMS OF PARATHYROID HORMONE-STIMULATED AND PARATHYROID HORMONE-RELATED-PEPTIDE-STIMULATED OSTEOCLAST-LIKE CELL-FORMATION FROM HEMATOPOIETIC BLAST CELLS
Mineral and electrolyte metabolism
INHIBITORY EFFECT OF ZINC-CHELATING DIPEPTIDE ON PARATHYROID HORMONE-STIMULATED OSTEOCLAST-LIKE CELL-FORMATION IN MOUSE MARROW CULTURES - INVOLVEMENT OF CALCIUM SIGNALING
Peptides
LOCAL CONCENTRATIONS OF MACROPHAGE-COLONY-STIMULATING FACTOR MEDIATE OSTEOCLASTIC DIFFERENTIATION
American journal of physiology: endocrinology and metabolism
MECHANISMS OF CELLULAR RECRUITMENT IN ASEPTIC LOOSENING OF PROSTHETICJOINT IMPLANTS
Calcified tissue international
BONE-RESORBING ACTIVITIES OF 24-EPI-1-ALPHA-HYDROXYVITAMIN D-2 AND 24-EPI-1-ALPHA-25-DIHYDROXYVITAMIN D-2
Calcified tissue international