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La ricerca find articoli where soggetti phrase all words 'OROTATE PHOSPHORIBOSYLTRANSFERASE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 49 riferimenti
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    1. Fukushima, M; Fujioka, A; Uchida, J; Nakagawa, F; Takechi, T
      Thymidylate synthase (TS) and ribonucleotide reductase (RNR) may be involved in acquired resistance to 5-fluorouracil (5-FU) in human cancer xenografts in vivo

      EUROPEAN JOURNAL OF CANCER
    2. Ashihara, H; Loukanina, N; Stasolla, C; Thorpe, TA
      Pyrimidine metabolism during somatic embryo development in white spruce (Picea glauca)

      JOURNAL OF PLANT PHYSIOLOGY
    3. Aronov, AM; Munagala, NR; Kuntz, ID; Wang, CC
      Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    4. Smiley, JA; Hay, KM; Levison, BS
      A reexamination of the substrate utilization of 2-thioorotidine-5 '-monophosphate by yeast orotidine-5 '-monophosphate decarboxylase

      BIOORGANIC CHEMISTRY
    5. Eriksen, TA; Kadziola, A; Bentsen, AK; Harlow, KW; Larsen, S
      Structural basis for the function of Bacillus subtilis phosphoribosylpyrophosphate synthetase

      NATURE STRUCTURAL BIOLOGY
    6. Munagala, N; Sarver, AE; Wang, CC
      Converting the guanine phosphoribosyltransferase from Giardia lamblia to ahypoxanthine-guanine phosphoribosyltransferase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    7. Harris, P; Poulsen, JCN; Jensen, KF; Larsen, S
      Structural basis for the catalytic mechanism of a proficient enzyme: Orotidine 5 '-monophosphate decarboxylase

      BIOCHEMISTRY
    8. Smith, JL
      Forming and inhibiting PRT active sites

      NATURE STRUCTURAL BIOLOGY
    9. Shi, WX; Li, CM; Tyler, PC; Furneaux, RH; Grubmeyer, C; Schramm, VL; Almo, SC
      The 2.0 angstrom structure of human hypoxanthineguanine phosphoribosyltransferase in complex with a transition-state analog inhibitor

      NATURE STRUCTURAL BIOLOGY
    10. Balendiran, GK; Molina, JA; Xu, YM; Torres-Martinez, J; Stevens, R; Focia, PJ; Eakin, AE; Sacchettini, JC; Craig, SP
      Ternary complex structure of human HGPRTase, PRPP, Mg2+, and the inhibitorHPP reveals the involvement of the flexible loop in substrate binding

      PROTEIN SCIENCE
    11. Bai, XY; Larsen, M; Meinhardt, F
      The URA5 gene encoding orotate-phosphoribosyl transferase of the yeast Kluyveromyces lactis: Cloning, sequencing and use as a selectable marker

      YEAST
    12. Phillips, CL; Ullman, B; Brennan, RG; Hill, CP
      Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani

      EMBO JOURNAL
    13. Watrin, L; Lucas, S; Purcarea, C; Legrain, C; Prieur, D
      Isolation and characterization of pyrimidine auxotrophs, and molecular cloning of the pyrE gene from the hyperthermophilic archaeon Pyrococcus abyssi

      MOLECULAR AND GENERAL GENETICS
    14. Hamana, H; Shinozawa, T
      Effects of C-terminal deletion on the activity and thermostability of orotate phosphoribosyltransferase from Thermus thermophilus

      JOURNAL OF BIOCHEMISTRY
    15. Page, JP; Munagala, NR; Wang, CC
      Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    16. Cheong, CG; Escalante-Semerena, JC; Rayment, I
      The three-dimensional structures of nicotinate mononucleotide : 5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 angstrom resolution

      BIOCHEMISTRY
    17. Lundegaard, C; Jensen, KF
      Kinetic mechanism of uracil phosphoribosyltransferase from Escherichia coli and catalytic importance of the conserved proline in the PRPP binding site

      BIOCHEMISTRY
    18. Wang, GP; Lundegaard, C; Jensen, KF; Grubmeyer, C
      Kinetic mechanism of OMP synthase: A slow physical step following group transfer limits catalytic rate

      BIOCHEMISTRY
    19. Wang, GP; Cahill, SM; Liu, XH; Girvin, ME; Grubmeyer, C
      Motional dynamics of the catalytic loop in OMP synthase

      BIOCHEMISTRY
    20. Javaid, ZZ; el Kouni, MH; Iltzsch, MH
      Pyrimidine nucleobase ligands of orotate phosphoribosyltransferase from Toxoplasma gondii

      BIOCHEMICAL PHARMACOLOGY
    21. Witte, JF; Tsou, R; McClard, RW
      Cloning, overproduction, and purification of native and mutant recombinantyeast orotate phosphoribosyltransferase and the demonstration from magnetization inversion transfer that a proposed oxocarbocation intermediate does not have a kinetic lifetime

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    22. TOMCHICK DR; TURNER RJ; SWITZER RL; SMITH JL
      ADAPTATION OF AN ENZYME TO REGULATORY FUNCTION - STRUCTURE OF BACILLUS-SUBTILIS PYRR, A PYR RNA-BINDING ATTENUATION PROTEIN AND URACIL PHOSPHORIBOSYLTRANSFERASE

      Structure
    23. Sharma, V; Grubmeyer, C; Sacchettini, JC
      Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target

      STRUCTURE
    24. MUCHMORE CRA; KRAHN JM; KIM JH; ZALKIN H; SMITH JL
      CRYSTAL-STRUCTURE OF GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE FROM ESCHERICHIA-COLI

      Protein science
    25. Smith, JL
      Glutamine PRPP amidotransferase: snapshots of an enzyme in action

      CURRENT OPINION IN STRUCTURAL BIOLOGY
    26. Grandori, R
      Systematic fold recognition analysis of the sequences encoded by the genome of Mycoplasma pneumoniae

      PROTEIN ENGINEERING
    27. SCHUMACHER MA; CARTER D; SCOTT DM; ROOS DS; ULLMAN B; BRENNAN RG
      CRYSTAL-STRUCTURES OF TOXOPLASMA-GONDII URACIL PHOSPHORIBOSYLTRANSFERASE REVEAL THE ATOMIC BASIS OF PYRIMIDINE DISCRIMINATION AND PRODRUG BINDING

      EMBO journal (Print)
    28. SCHRAMM VL
      ENZYMATIC TRANSITION-STATES AND TRANSITION-STATE ANALOG DESIGN

      Annual review of biochemistry
    29. UNRAU PJ; BARTEL DP
      RNA-CATALYZED NUCLEOTIDE SYNTHESIS

      Nature
    30. VOS S; PARRY RJ; BURNS MR; DEJERSEY J; MARTIN JL
      STRUCTURES OF FREE AND COMPLEXED FORMS OF ESCHERICHIA-COLI XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE

      Journal of Molecular Biology
    31. FOCIA PJ; CRAIG SP; NIEVESALICEA R; FLETTERICK RJ; EAKIN AE
      A 1.4 ANGSTROM CRYSTAL-STRUCTURE FOR THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE OF TRYPANOSOMA-CRUZI

      Biochemistry (Easton)
    32. MUNAGALA NR; CHIN MS; WANG CC
      STEADY-STATE KINETICS OF THE HYPOXANTHINE-GUANINE-XANTHINE PHOSPHORIBOSYLTRANSFERASE FROM TRITRICHOMONAS-FETUS - THE ROLE OF THREONINE-47

      Biochemistry
    33. XU YM; GRUBMEYER C
      CATALYSIS IN HUMAN HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE - ASP-137 ACTS AS A GENERAL ACID BASE/

      Biochemistry
    34. GROSS JW; RAJAVEL M; GRUBMEYER C
      KINETIC MECHANISM OF NICOTINIC-ACID PHOSPHORIBOSYLTRANSFERASE - IMPLICATIONS FOR ENERGY COUPLING

      Biochemistry
    35. Focia, PJ; Craig, SP; Eakin, AE
      Approaching the transition state in the crystal structure of a phosphoribosyltransferase

      BIOCHEMISTRY
    36. PARRY RJ; BURNS MR; JIRALERSPONG S; ALEMANY L
      SYNTHESIS OF (-(1S)-1-PYROPHOSPHORYL-(2R, IHYDROXY-(4S)-4-(PHOSPHORYLOXYMETHYL)CYCLOPENTANE, A STABLE, OPTICALLY-ACTIVE CARBOCYCLIC ANALOG OF 5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP)())

      Tetrahedron
    37. JARDIM A; ULLMAN B
      THE CONSERVED SERINE-TYROSINE DIPEPTIDE IN LEISHMANIA-DONOVANI HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IS ESSENTIAL FOR CATALYTIC ACTIVITY

      The Journal of biological chemistry
    38. KRAHN JM; KIM JH; BURNS MR; PARRY RJ; ZALKIN H; SMITH JL
      COUPLED FORMATION OF AN AMIDOTRANSFERASE INTERDOMAIN AMMONIA CHANNEL AND A PHOSPHORIBOSYLTRANSFERASE ACTIVE-SITE

      Biochemistry
    39. VOS S; DEJERSEY J; MARTIN JL
      CRYSTAL-STRUCTURE OF ESCHERICHIA-COLI XANTHINE PHOSPHORIBOSYLTRANSFERASE

      Biochemistry
    40. XU YM; EADS J; SACCHETTINI JC; GRUBMEYER C
      KINETIC MECHANISM OF HUMAN HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE - RAPID PHOSPHORIBOSYL TRANSFER CHEMISTRY

      Biochemistry
    41. KIMURA E; KITAMURA H; KOIKE T; SHIRO M
      FACILE AND SELECTIVE ELECTROSTATIC STABILIZATION OF URACIL N(1)(-) ANION BY A PROXIMATE PROTONATED AMINE - A CHEMICAL IMPLICATION FOR WHY URACIL N(1) IS CHOSEN FOR GLYCOSYLATION SITE

      Journal of the American Chemical Society
    42. PHILLIPS CL; ULLMAN B; BRENNAN RG
      CRYSTALLIZATION OF THE PURINE SALVAGE ENZYME ADENINE PHOSPHORIBOSYLTRANSFERASE

      Proteins
    43. WITTE JF; MCCLARD RW
      C-GLYCOSYLPHOSPHONYL ANALOGS OF 5-PHOSPHORYLRIBOSE 1-ALPHA-DIPHOSPHATE .2. THE 2-DEOXY ANALOG

      Bioorganic chemistry
    44. JENSEN KF; MYGIND B
      DIFFERENT OLIGOMERIC STATES ARE INVOLVED IN THE ALLOSTERIC BEHAVIOR OF URACIL PHOSPHORIBOSYLTRANSFERASE FROM ESCHERICHIA-COLI

      European journal of biochemistry
    45. LIN T; SUTTLE DP
      UMP SYNTHASE ACTIVITY EXPRESSED IN DEFICIENT HAMSTER-CELLS BY SEPARATE TRANSFERASE AND DECARBOXYLASE PROTEINS OR BY LINKER-DELETED BIFUNCTIONAL PROTEIN

      Somatic cell and molecular genetics
    46. PEKARSKY Y; ZABAROVSKY E; KASHUBA V; DRABKIN H; SANDBERG AA; MORGAN R; RYNDITCH A; GARDINER K
      CLONING OF BREAKPOINTS IN 3Q21 ASSOCIATED WITH HEMATOLOGIC MALIGNANCY

      Cancer genetics and cytogenetics
    47. BUNNAK J; HAMANA H; OGINO Y; SAHEKI T; YAMAGISHI A; OSHIMA T; DATE T; SHINOZAWA T
      OROTATE PHOSPHORIBOSYLTRANSFERASE FROM THERMUS-THERMOPHILUS - OVEREXPRESSION IN ESCHERICHIA-COLI, PURIFICATION AND CHARACTERIZATION

      Journal of Biochemistry
    48. KANAANI J; MALTBY D; FOCIA P; WANG CC
      IDENTIFICATION OF THE ACTIVE-SITES OF HUMAN AND SCHISTOSOMAL HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASES BY GMP-2',3'-DIALDEHYDE AFFINITY LABELING

      Biochemistry
    49. BARNES T; PARRY P; HART I; JONES C; MINET M; PATTERSON D
      REGIONAL MAPPING OF THE GENE ENCODING DIHYDROOROTATE DEHYDROGENASE, AN ENZYME INVOLVED IN UMP SYNTHESIS, ELECTRON-TRANSPORT, AND SUPEROXIDEGENERATION, TO HUMAN-CHROMOSOME REGION-16Q22

      Somatic cell and molecular genetics


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Documento generato il 21/10/20 alle ore 11:05:10