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Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
TRENDS IN MOLECULAR MEDICINE
Dioxin toxicology and the aryl hydrocarbon receptor: Insights from fish and other non-traditional models
MARINE BIOTECHNOLOGY
Interactions between aryl hydrocarbon receptor (AhR) and hypoxia signalingpathways
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
Defective development of secretory neurones in the hypothalamus of Arnt2-knockout mice
GENES TO CELLS
cDNA cloning and characterization of a high affinity aryl hydrocarbon receptor in a cetacean, the beluga, Delphinapterus leucas
TOXICOLOGICAL SCIENCES
Correlation of cardiotoxicity mediated by halogenated aromatic hydrocarbons to aryl hydrocarbon receptor activation
TOXICOLOGICAL SCIENCES
Association of ARNT splice variants with estrogen receptor-negative breastcancer, poor induction of vascular endothelial growth factor under hypoxia, and poor prognosis
CLINICAL CANCER RESEARCH
Establishment of a human hepatocyte line (OUMS-29) having CYP 1A1 and 1A2 activities from fetal liver tissue by transfection of SV-10 LT
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor
CELL GROWTH & DIFFERENTIATION
Suppression of cytochrome P450 1A1 and 4A1 gene expression in renal carcinomas of TSC2 gene mutant (Eker) rats
INTERNATIONAL JOURNAL OF ONCOLOGY
Induction of cytochrome P450 1A1 gene expression by a vitamin K-3 analog in mouse hepatoma Hepa-1c1c7 cells
MOLECULES AND CELLS
The effect of the arylhydrocarbon receptor on the human steroidogenic acute regulatory gene promoter activity
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
Molecular cloning and embryonic expression of the Xenopus Arnt gene
MECHANISMS OF DEVELOPMENT
An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Myaarenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and beta-naphthoflavone binding
GENE
Competitive inhibition of the transcription of rabbit CYP1A1 gene by upstream stimulatory factor 1 (USF1)
DRUG METABOLISM REVIEWS
Hormonal control of arylhydrocarbon receptor (AhR) expression in the preimplantation rabbit uterus
ANATOMY AND EMBRYOLOGY
Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio)
ENVIRONMENTAL HEALTH PERSPECTIVES
Persistent, low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Effect on aryl hydrocarbon receptor expression in a dioxin-resistance model
TOXICOLOGY AND APPLIED PHARMACOLOGY
Regulation of Cyp1a1 induction by dioxin as a function of cell cycle phase
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Conditional transgenic technologies
JOURNAL OF ENDOCRINOLOGY
Arylhydrocarbon receptor (AhR) is involved in negative regulation of adipose differentiation in 3T3-L1 cells: AhR inhibits adipose differentiation independently of dioxin
JOURNAL OF CELL SCIENCE
The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity
JOURNAL OF BIOLOGICAL CHEMISTRY
Dioxin-inducible transactivation in a chromosomal setting - Analysis of the acidic domain of the Ah receptor
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of genes differentially induced by hypoxia in pancreatic cancer cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
The AH receptor of the most dioxin-sensitive species, guinea pig, is highly homologous to the human AH receptor
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Hypoxia-inducible factor 1 alpha and 1 beta proteins share common signaling pathways in human prostate cancer cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Overexpression of a zebrafish ARNT2-like factor represses CYP1A transcription in ZLE cells
MARINE BIOTECHNOLOGY
Molecular characterization and developmental expression of the aryl hydrocarbon receptor from the chick embryo
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
Transactivation mechanisms of mouse clock transcription factors, mClock and mArnt3
GENES TO CELLS
Developmental and tissue-specific expression of AHR1, AHR2, and ARNT2 in dioxin-sensitive and -resistant populations of the marine fish Fundulus heteroclitus
TOXICOLOGICAL SCIENCES
Placental defects in ARNT-knockout conceptus correlate with localized decreases in VEGF-R2, Ang-1, and Tie-2
DEVELOPMENTAL DYNAMICS
Estrogen enhances induction of cytochrome P-4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin in lives of female Long-Evans rats
INTERNATIONAL JOURNAL OF ONCOLOGY
Two splice variants of the hypoxia-inducible factor HIF-1 alpha as potential dimerization partners of ARNT2 in neurons
EUROPEAN JOURNAL OF NEUROSCIENCE
Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS
DEVELOPMENT
Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development
MECHANISMS OF DEVELOPMENT
Effect of dioxin on the gene promoters
BIOMEDICAL RESEARCH-TOKYO
The PAS superfamily: Sensors of environmental and developmental signals
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
Aryl hydrocarbon receptor nuclear translocator is induced by kainic acid in rat hippocampal glial cells
NEUROSCIENCE LETTERS
Receptor-mediated effects of chlorinated hydrocarbons
ANDROLOGIA
Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1 alpha
MOLECULAR AND CELLULAR BIOLOGY
Identification and expression of alternatively spliced aryl hydrocarbon nuclear translocator 2 (ARNT2) cDNAs from zebrafish with distinct functions
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Nuclear trafficking of metallothionein: Possible mechanisms and current knowledge
CELLULAR AND MOLECULAR BIOLOGY
The evolution of aryl hydrocarbon signaling proteins: diversity of ARNT isoforms among fish species
MARINE ENVIRONMENTAL RESEARCH
Cell biology of cytochrome P-450 in the liver
INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 198
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of cytochrome P450 1A1, the aryl hydrocarbon receptor, and the aryl hydrocarbon receptor nuclear translocator in rat brain and pituitary
TOXICOLOGY AND APPLIED PHARMACOLOGY
The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocytes and their response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
TOXICOLOGY AND APPLIED PHARMACOLOGY
A tetratricopeptide repeat half-site in the aryl hydrocarbon receptor is important for DNA binding and trans-activation potential
MOLECULAR PHARMACOLOGY
The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B cell apoptosis
MOLECULAR PHARMACOLOGY
Role of heat shock protein 90 dissociation in mediating agonist-induced activation of the aryl hydrocarbon receptor
MOLECULAR PHARMACOLOGY
Putative link between transcriptional regulation of IgM expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin and the aryl hydrocarbon receptor/dioxin-responsive enhancer signaling pathway
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
A CCAAT/enhancer-binding protein site within antioxidant/electrophile response element along with CREB-binding protein participate in the negative regulation of rat GST-Ya gene in vascular smooth muscle cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Superinduction of CYP1A1 gene expression - Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide
JOURNAL OF BIOLOGICAL CHEMISTRY
2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway - Role of the transcription activaton and DNA binding of AhR
JOURNAL OF BIOLOGICAL CHEMISTRY
Nucleocytoplasmic shuttling of the aryl hydrocarbon receptor
JOURNAL OF BIOCHEMISTRY
Different transcriptional properties of mSim-1 and mSim-2
FEBS LETTERS
Estrous cycle-dependent changes in the expression of aromatic hydrocarbon receptor (AHR) and AHR-nuclear translocator (ARNT) mRNAs in the rat ovary and liver
CHEMICO-BIOLOGICAL INTERACTIONS
Restructured transactivation domain in hamster AH receptor
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Effects of histone deacetylase inhibitors on the Ah receptor gene promoter
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERR alpha 1
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Expression and subcellular localization of the aryl hydrocarbon receptor nuclear translocator (ARNT) protein in mouse and chicken over developmental time
ANATOMICAL RECORD
Differential gene expression in wild-type and Arnt-defective mouse hepatoma (Hepa1c1c7) cells
TOXICOLOGICAL SCIENCES
AhR, ARNT, and CYP1A1 mRNA quantitation in cultured human embryonic palates exposed to TCDD and comparison with mouse palate in vivo and in culture
TOXICOLOGICAL SCIENCES
RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone
TOXICOLOGICAL SCIENCES
Regulation of mammalian O-2 homeostasis by hypoxia- inducible factor 1
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
ARNT2, a transcription factor for brain neuron survival?
EUROPEAN JOURNAL OF NEUROSCIENCE
The spineless-Aristapedia and tango bHLH-PAS proteins interact to control antennal and tarsal development in Drosophila
DEVELOPMENT
Identification of a novel mechanism of regulation of Ah (dioxin) receptor function
GENES & DEVELOPMENT
Specificity of DNA binding of the c-Myc/Max and ARNT/ARNT dimers at the CACGTG recognition site
NUCLEIC ACIDS RESEARCH
Molecular mechanisms of transcription activation by HLF and HIF1 alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300
EMBO JOURNAL
Cloning and characterization of the zebrafish (Danio rerio) aryl hydrocarbon receptor
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
A human aryl hydrocarbon receptor signaling pathway constructed in yeast displays additive responses to ligand mixtures
TOXICOLOGY AND APPLIED PHARMACOLOGY
Induction of arylhydrocarbon receptor expression in embryoblast cells of rabbit preimplantation blastocysts upon degeneration of Rauber's polar trophoblast
TOXICOLOGY AND APPLIED PHARMACOLOGY
Ah receptor and ARNT protein and mRNA concentrations in rat prostate: Effects of stage of development and 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment
TOXICOLOGY AND APPLIED PHARMACOLOGY
Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains
TOXICOLOGY AND APPLIED PHARMACOLOGY
Differential response to benzo[a]pyrene in human lung adenocarcinoma cell lines: The absence of aryl hydrocarbon receptor activation
LIFE SCIENCES
Degradation of the basic helix-loop-helix/Per-ARNT-Sim homology domain dioxin receptor via the ubiquitin/proteasome pathway
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification and functional characterization of two highly divergent aryl hydrocarbon receptors (AHR1 and AHR2) in the teleost Fundulus heteroclitus - Evidence for a novel subfamily of ligand-binding basic helix loop helix-Per-ARNT-Sim (bHLH-PAS) factors
JOURNAL OF BIOLOGICAL CHEMISTRY
Two forms of aryl hydrocarbon receptor type 2 in rainbow trout (Oncorhynchus mykiss) - Evidence for differential expression and enhancer specificity
JOURNAL OF BIOLOGICAL CHEMISTRY
Evidence that the Co-chaperone p23 regulates ligand responsiveness of the dioxin (aryl hydrocarbon) receptor
JOURNAL OF BIOLOGICAL CHEMISTRY
Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways - Demonstration of competition and compensation
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization
BIOCHEMISTRY
Divergent mechanisms for loss of Ah-responsiveness in benzo[a]pyrene- and Adriamycin(R)-resistant MCF-7 cells
BIOCHEMICAL PHARMACOLOGY
Angiogenesis: How a tumor adapts to hypoxia
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Lack of an absolute requirement for the native aryl hydrocarbon receptor (AhR) and AhR nuclear translocator transactivation domains in protein kinaseC-mediated modulation of the AhR pathway
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Functional diversity of vertebrate ARNT proteins: Identification of ARNT2 as the predominant form of ARNT in the marine teleost, Fundulus heteroelitus
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
The aryl hydrocarbon receptor: A comparative perspective
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
FEMALE SPRAGUE-DAWLEY RATS EXPOSED TO A SINGLE ORAL DOSE OF 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN EXHIBIT SUSTAINED DEPLETION OF ARYL-HYDROCARBON RECEPTOR PROTEIN IN LIVER, SPLEEN, THYMUS, AND LUNG
TOXICOLOGICAL SCIENCES
HYPOXIA-INDUCIBLE-FACTOR-1 - MASTER REGULATOR OF O-2 HOMEOSTASIS
Current opinion in genetics & development
REGULATION OF BHLH-PAS PROTEIN SUBCELLULAR-LOCALIZATION DURING DROSOPHILA EMBRYOGENESIS
Development
EXPRESSION OF ARNT, ARNT2, HIF1-ALPHA, HIF2-ALPHA AND AH RECEPTOR MESSENGER-RNAS IN THE DEVELOPING MOUSE
Mechanisms of development
CONTROL OF CELL LINEAGE-SPECIFIC DEVELOPMENT AND TRANSCRIPTION BY BHLH-PAS PROTEINS
Genes & development
CELLULAR AND DEVELOPMENTAL CONTROL OF O-2 HOMEOSTASIS BY HYPOXIA-INDUCIBLE FACTOR 1-ALPHA
Genes & development
TRANSCRIPTIONAL ACTIVATION OF CYTOCHROME-P450 GENES BY DIFFERENT CLASSES OF CHEMICAL INDUCERS
Clinical and experimental pharmacology and physiology
HEPATITIS-B VIRUS X-ASSOCIATED PROTEIN-2 IS A SUBUNIT OF THE UNLIGANDED ARYL-HYDROCARBON RECEPTOR CORE COMPLEX AND EXHIBITS TRANSCRIPTIONALENHANCER ACTIVITY
Molecular and cellular biology
CONSTITUTIVE ACTIVATION OF THE AROMATIC HYDROCARBON RECEPTOR
Molecular and cellular biology
MECHANISMS OF LIGAND-INDUCED ARYL-HYDROCARBON RECEPTOR-MEDIATED BIOCHEMICAL AND TOXIC RESPONSES
Toxicologic pathology
CHARACTERIZATION OF 2 CONTINUOUS CELL-LINES DERIVED FROM ONCORHYNCHUS-MYKISS FOR MODELS OF ARYL-HYDROCARBON-RECEPTOR-MEDIATED SIGNAL-TRANSDUCTION - DIRECT COMPARISON TO THE MAMMALIAN HEPA-1C1C7 CELL-LINE
Aquatic toxicology
FUNCTIONAL-CHARACTERIZATION OF THE HUMAN CYP1A1 NEGATIVE REGULATORY ELEMENT - MODULATION OF AH RECEPTOR-MEDIATED TRANSCRIPTIONAL ACTIVITY
Carcinogenesis
ENHANCEMENT OF ALLERGIC INFLAMMATION BY THE INTERACTION BETWEEN DIESEL EXHAUST PARTICLES AND THE IMMUNE-SYSTEM
Journal of allergy and clinical immunology
The aryl hydrocarbon receptor - Studies using the AHR-null mice
DRUG METABOLISM AND DISPOSITION