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La ricerca find articoli where soggetti phrase all words 'NUCLEAR ACCUMULATION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 90 riferimenti
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    1. Matwee, C; Kamaruddin, M; Betts, DH; Basrur, PK; King, WA
      The effects of antibodies to heat shock protein 70 in fertilization and embryo development

      MOLECULAR HUMAN REPRODUCTION
    2. Bernardini, S; Chabannes, E; Bittard, H
      Value of p53 in the clinical management of bladder cancer.

      PROGRES EN UROLOGIE
    3. Manne, U; Gary, BD; Oelschlager, DK; Weiss, HL; Frost, AR; Grizzle, WE
      Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas

      CLINICAL CANCER RESEARCH
    4. Otsuki, T; Furukawa, Y; Ikeda, K; Endo, H; Yamashita, T; Shinohara, A; Iwamatsu, A; Ozawa, K; Liu, JM
      Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex

      HUMAN MOLECULAR GENETICS
    5. Fukuhara, Y; Takeshima, T; Kashiwaya, Y; Shimoda, K; Ishitani, R; Nakashima, K
      GAPDH knockdown rescues mesencephalic dopaminergic neurons from MPP+-induced apoptosis

      NEUROREPORT
    6. Eymin, B; Gazzeri, S; Brambilla, C; Brambilla, E
      Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma

      ONCOGENE
    7. Huang, TG; Ip, SM; Yeung, WSB; Ngan, HYS
      Mitomycin C and cisplatin enhanced the antitumor activity of p53-expressing adenovirus in cervical cancer cells

      CANCER INVESTIGATION
    8. Lu, Y; Lian, HZ; Sharma, P; Schreiber-Agus, N; Russell, RG; Chin, L; van der Horst, GTJ; Bregman, DB
      Disruption of the Cockayne syndrome B gene impairs spontaneous tumorigenesis in cancer-predisposed Ink4a/ARF knockout mice

      MOLECULAR AND CELLULAR BIOLOGY
    9. Omar, EA; Behlouli, H; Chevalier, S; Aprikian, AG
      Relationship of p21(WAF-1) protein expression with prognosis in advanced prostate cancer treated by androgen ablation

      PROSTATE
    10. Gibbons, MD; Manne, U; Carroll, WR; Peters, GE; Weiss, HL; Grizzle, WE
      Molecular differences in mucoepidermoid carcinoma and adenoid cystic carcinoma of the major salivary glands

      LARYNGOSCOPE
    11. Zammit, C; Barnard, R; Gomm, J; Coope, R; Shousha, S; Coombes, C; Johnston, C
      Altered intracellular localization of fibroblast growth factor receptor 3 in human breast cancer

      JOURNAL OF PATHOLOGY
    12. Cornelussen, RNM; Gupta, S; Knowlton, AA
      Regulation of prostaglandin A(1)-induced heat shock protein expression in isolated cardiomyocytes

      JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
    13. Wong, CM; Fan, ST; Ng, IOL
      beta-Catenin mutation and overexpression in hepatocellular carcinoma - Clinicopathologic and prognostic significance

      CANCER
    14. Semba, S; Han, SY; Ikeda, H; Horii, A
      Frequent nuclear accumulation of beta-catenin in pituitary adenoma

      CANCER CYTOPATHOLOGY
    15. Semba, S; Han, SY; Ikeda, H; Horii, A
      Frequent nuclear accumulation of beta-catenin in pituitary adenoma

      CANCER
    16. Futaki, M; Watanabe, S; Kajigaya, S; Liu, JM
      Fanconi anemia protein, FANCG, is a phosphoprotein and is upregulated withFANCA after TNF-alpha treatment

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    17. Morris, L; Allen, KE; La Thangue, NB
      Regulation of E2F transcription by cyclinE-Cdk2 kinase mediated through p300/CBP co-activators

      NATURE CELL BIOLOGY
    18. Manne, U; Weiss, HL; Grizzle, WE
      Racial differences in the prognostic usefulness of MUC1 and MUC2 in colorectal adenocarcinomas

      CLINICAL CANCER RESEARCH
    19. Frost, AR; Sparks, D; Grizzle, WE
      Methods of antigen recovery vary in their usefulness in unmasking specificantigens in immunohistochemistry

      APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
    20. Piyathilake, CJ; Johanning, GL; Frost, AR; Whiteside, MA; Manne, U; Grizzle, WE; Heimburger, DC; Niveleau, A
      Immunohistochemical evaluation of global DNA methylation: Comparison with in vitro radiolabeled methyl incorporation assay

      BIOTECHNIC & HISTOCHEMISTRY
    21. Semba, S; Kusumi, R; Moriya, T; Sasano, H
      Nuclear accumulation of beta-catenin in human endocrine tumors: Association with Ki-67 (MIB-1) proliferative activity

      ENDOCRINE PATHOLOGY
    22. Delrieu, I; Chinestra, P; Delassus, F; Bayard, F; Prats, H; Faye, JC
      IL-6 promoter is modulated by the 24 kDda FGF-2 isoform fused to the hormone binding domain of the oestrogen receptor

      CYTOKINE
    23. Noda, A; Toma-Aiba, Y; Fujiwara, Y
      A unique, short sequence determines p53 gene basal and UV-inducible expression in normal human cells

      ONCOGENE
    24. Miyazawa, K; Iwaya, K; Kuroda, M; Harada, M; Serizawa, H; Koyanagi, Y; Sato, Y; Mizokami, Y; Matsuoka, T; Mukai, K
      Nuclear accumulation of beta-catenin in intestinal-type gastric carcinoma:correlation with early tumor invasion

      VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
    25. Saito, N; Yamamoto, T; Watanabe, T; Abe, Y; Kumagai, T
      Implications of p53 protein expression in experimental spinal cord injury

      JOURNAL OF NEUROTRAUMA
    26. Wong, JCY; Alon, N; Norga, K; Kruyt, FAE; Youssoufian, H; Buchwald, M
      Cloning and analysis of the mouse Fanconi anemia group a cDNA and an overlapping penta zinc finger cDNA

      GENOMICS
    27. Loughran, O; La Thangue, NB
      Apoptotic and growth-promoting activity of E2F modulated by MDM2

      MOLECULAR AND CELLULAR BIOLOGY
    28. Wu, HH; Thomas, JA; Momand, J
      p53 protein oxidation in cultured cells in response to pyrrolidine dithiocarbamate: a novel method for relating the amount of p53 oxidation in vivo to the regulation of p53-responsive genes

      BIOCHEMICAL JOURNAL
    29. Martinez-Balbas, MA; Bauer, UM; Nielsen, SJ; Brehm, A; Kouzarides, T
      Regulation of E2F1 activity by acetylation

      EMBO JOURNAL
    30. Piyathilake, CJ; Frost, AR; Weiss, H; Manne, U; Heimburger, DC; Grizzle, WE
      The expression of Ep-CAM (17-1A) in squamous cell cancers of the lung

      HUMAN PATHOLOGY
    31. Ghosh, JC; Izumida, Y; Suzuki, K; Kodama, S; Watanabe, M
      Dose-dependent biphasic accumulation of TP53 protein in normal human embryo cells after X irradiation

      RADIATION RESEARCH
    32. Steven, K; Poulsen, AL
      The orthotopic Kock ileal neobladder: Functional results, urodynamic features, complications and survival in 166 men

      JOURNAL OF UROLOGY
    33. Manne, U; Weiss, HL; Grizzle, WE
      Bcl-2 expression is associated with improved prognosis in patients with distal colorectal adenocarcinomas

      INTERNATIONAL JOURNAL OF CANCER
    34. Delrieu, I
      The high molecular weight isoforms of basic fibroblast growth factor (FGF-2): an insight into an intracrine mechanism

      FEBS LETTERS
    35. Roviello, F; Marrelli, D; Vindigni, C; De Stefano, A; Spina, D; Pinto, E
      p53 accumulation is a prognostic factor in intestinal-type gastric carcinoma but not in the diffuse type

      ANNALS OF SURGICAL ONCOLOGY
    36. Blattner, C; Tobiasch, E; Litfen, M; Rahmsdorf, HJ; Herrlich, P
      DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation

      ONCOGENE
    37. Corbet, SW; Clarke, AR; Gledhill, S; Wyllie, AH
      P53-dependent and -independent links between DNA-damage, apoptosis and mutation frequency in ES cells

      ONCOGENE
    38. Ohta, M; Nitta, M; Yamaizumi, M
      High sensitivity of the ultraviolet-induced p53 response in ultraviolet-sensitive syndrome, a photosensitive disorder with a putative defect in deoxyribonucleic acid repair of actively transcribed genes

      MUTATION RESEARCH-DNA REPAIR
    39. Yamada, SM; Yamaguchi, F; Brown, R; Berger, MS; Morrison, RS
      Suppression of glioblastoma cell growth following antisense oligonucleotide-mediated inhibition of fibroblast growth factor receptor expression

      GLIA
    40. Passinen, S; Haverinen, M; Pekki, A; Rauta, J; Paranko, J; Syvala, H; Tuohimaa, P; Ylikomi, T
      Only a small portion of the cytoplasmic progesterone receptor is associated with Hsp90 in vivo

      JOURNAL OF CELLULAR BIOCHEMISTRY
    41. Friesel, R; Maciag, T
      Fibroblast growth factor prototype release and fibroblast growth factor receptor signaling

      THROMBOSIS AND HAEMOSTASIS
    42. Nakagawa, K; Taya, Y; Tamai, K; Yamaizumi, M
      Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks

      MOLECULAR AND CELLULAR BIOLOGY
    43. Jain, PT; Seth, P; Gewirtz, DA
      Estradiol enhances liposome-mediated uptake, preferential nuclear accumulation and functional expression of exogenous genes in MDA-MB231 breast tumorcells

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
    44. Duerksen-Hughes, PJ; Yang, J; Ozcan, O
      p53 induction as a genotoxic test for twenty-five chemicals undergoing in vivo carcinogenicity testing

      ENVIRONMENTAL HEALTH PERSPECTIVES
    45. Zhirnov, OP; Konakova, TE; Garten, W; Klenk, HD
      Caspase-dependent N-terminal cleavage of influenza virus nucleocapsid protein in infected cells

      JOURNAL OF VIROLOGY
    46. Haapajarvi, T; Kivinen, L; Heiskanen, A; des Bordes, C; Datto, MB; Wang, XF; Laiho, M
      UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner

      EXPERIMENTAL CELL RESEARCH
    47. Sheikh, F; Fandrich, RR; Kardami, E; Cattini, PA
      Overexpression of long or short FGFR-1 results in FGF-2-mediated proliferation in neonatal cardiac myocyte cultures

      CARDIOVASCULAR RESEARCH
    48. Zhang, CC; Yang, JM; Bash-Babula, J; White, E; Murphy, M; Levine, AJ; Hait, WN
      DNA damage increases sensitivity to Vinca alkaloids and decreases sensitivity to taxanes through p53-dependent repression of microtubule-associated protein 4

      CANCER RESEARCH
    49. Kassner, PD; Burg, MA; Baird, A; Larocca, D
      Genetic selection of phage engineered for receptor-mediated gene transfer to mammalian cells

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    50. MERLIN T; BRANDNER G; HESS RD
      CELL-CYCLE ARREST IN OVARIAN-CANCER CELL-LINES DOES NOT DEPEND ON P53STATUS UPON TREATMENT WITH CYTOSTATIC DRUGS

      International journal of oncology
    51. Merkle, C; Fritsche, M; Mundt, M; Jahne, R; Groner, B
      Transcriptional regulation and induction of apoptosis: implications for the use of monomeric p53 variants in gene therapy

      GENE THERAPY
    52. TAUBERT H; WURL P; BACHE M; MEYE A; BERGER D; HOLZHAUSEN HJ; HINZE R; SCHMIDT H; RATH FW
      THE P53 GENE IN SOFT-TISSUE SARCOMAS - PROGNOSTIC VALUE OF DNA-SEQUENCING VERSUS IMMUNOHISTOCHEMISTRY

      Anticancer research
    53. EID H; GECZI L; BODROGI I; INSTITORIS E; BAK M
      DO METALLOTHIONEINS AFFECT THE RESPONSE TO TREATMENT IN TESTIS CANCERS

      Journal of cancer research and clinical oncology
    54. DICIOCCIO RA; WERNESS BA; PENG RQ; ALLEN HJ; PIVER MS
      CORRELATION OF TP53 MUTATIONS AND P53 EXPRESSION IN OVARIAN-TUMORS

      Cancer genetics and cytogenetics
    55. YANG J; DUERKSENHUGHES P
      A NEW APPROACH TO IDENTIFYING GENOTOXIC CARCINOGENS - P53 INDUCTION AS AN INDICATOR OF GENOTOXIC DAMAGE

      Carcinogenesis (New York. Print)
    56. ZHAO WQ; LI H; YAMASHITA K; GUO XK; HOSHINO T; YOSHIDA S; SHINYA T; HAYAKAWA T
      CELL CYCLE-ASSOCIATED ACCUMULATION OF TISSUE INHIBITOR OF METALLOPROTEINASES-1 (TIMP-1) IN THE NUCLEI OF HUMAN GINGIVAL FIBROBLASTS

      Journal of Cell Science
    57. LIANG SH; HONG D; CLARKE MF
      COOPERATION OF A SINGLE LYSINE MUTATION AND A C-TERMINAL DOMAIN IN THE CYTOPLASMIC SEQUESTRATION OF THE P53 PROTEIN

      The Journal of biological chemistry
    58. Manne, U; Weiss, HL; Myers, RB; Danner, OK; Moron, C; Srivastava, S; Grizzle, WE
      Nuclear accumulation of p53 in colorectal adenocarcinoma - Prognostic importance differs with race and location of the tumor

      CANCER
    59. LESEC G; RICHARDCOULET E; COLLET JF; DEMAUBLANC MA; MERLE S; SALMON RJ; REMVIKOS Y
      THE P53-POSITIVE PHENOTYPE OF BREAST CANCERS - CORRELATION WITH OTHERPARAMETERS AND CONSEQUENCES ON ITS BIOLOGICAL SIGNIFICANCE

      International journal of oncology
    60. NITTA M; OKAMURA H; AIZAWA S; YAMAIZUMI M
      HEAT-SHOCK INDUCES TRANSIENT P53-DEPENDENT CELL-CYCLE ARREST AT G1 S/

      Oncogene
    61. SCHWARTZ D; ALMOG N; PELED A; GOLDFINGER N; ROTTER V
      ROLE OF WILD-TYPE P53 IN THE G(2) PHASE - REGULATION OF THE GAMMA-IRRADIATION-INDUCED DELAY AND DNA-REPAIR

      Oncogene
    62. HESS RD; BRANDNER G
      DNA-DAMAGE-INDUCIBLE P53 ACTIVITY IN SV40-TRANSFORMED CELLS

      Oncogene
    63. NEWFELD SJ; MEHRA A; SINGER MA; WRANA JL; ATTISANO L; GELBART WM
      MOTHERS AGAINST DPP PARTICIPATES IN A DPP TGF-BETA RESPONSIVE SERINE-THREONINE KINASE SIGNAL-TRANSDUCTION CASCADE/

      Development
    64. NINOMIYA Y; URANO Y; YOSHIMOTO K; IWAHANA H; SASAKI S; ARASE S; ITAKURA M
      P53 GENE MUTATION ANALYSIS IN POROKERATOSIS AND POROKERATOSIS-ASSOCIATED SQUAMOUS-CELL CARCINOMA

      Journal of dermatological science
    65. DUMAZ N; DUTHU A; EHRHART JC; DROUGARD C; APPELLA E; ANDERSON CW; MAY P; SARASIN A; DAYAGROSJEAN L
      PROLONGED P53 PROTEIN ACCUMULATION IN TRICHOTHIODYSTROPHY FIBROBLASTSDEPENDENT ON UNREPAIRED PYRIMIDINE DIMERS ON THE TRANSCRIBED STRANDS OF CELLULAR GENES

      Molecular carcinogenesis
    66. FONTOURA BMA; ATIENZA CA; SOROKINA EA; MORIMOTO T; CARROLL RB
      CYTOPLASMIC P53 POLYPEPTIDE IS ASSOCIATED WITH RIBOSOMES

      Molecular and cellular biology
    67. MCKAY BC; FRANCIS MA; RAINBOW AJ
      WILDTYPE P53 IS REQUIRED FOR HEAT-SHOCK AND ULTRAVIOLET-LIGHT ENHANCED REPAIR OF A UV-DAMAGED REPORTER GENE

      Carcinogenesis
    68. DELAAT A; KROON ED; DEGRUIJL FR
      CELL-CYCLE EFFECTS AND CONCOMITANT P53 EXPRESSION IN HAIRLESS MURINE SKIN AFTER LONGWAVE UVA (365-NM) IRRADIATION - A COMPARISON WITH UVB IRRADIATION

      Photochemistry and photobiology
    69. PROWALD A; SCHUSTER N; MONTENARH M
      REGULATION OF THE DNA-BINDING OF P53 BY ITS INTERACTION WITH PROTEIN-KINASE CK2

      FEBS letters
    70. ISAACS JS; CHIAO C; MERRICK BA; SELKIRK JK; BARRETT JC; WEISSMAN BE
      P53-DEPENDENT P21 INDUCTION FOLLOWING GAMMA-IRRADIATION WITHOUT CONCOMITANT P53 INDUCTION IN A HUMAN PERIPHERAL NEUROEPITHELIOMA CELL-LINE

      Cancer research
    71. CERALINE J; DEPLANQUE G; DUCLOS B; LIMACHER JM; VINCENT F; GOLDBLUM S; BERGERAT JP
      RELATIONSHIPS BETWEEN P53 INDUCTION, CELL -CYCLE ARREST AND SURVIVAL OF NORMAL HUMAN FIBROBLASTS FOLLOWING DNA-DAMAGE

      Bulletin du cancer
    72. WAKASUGI E; KOBAYASHI T; TAMAKI Y; ITO Y; MIYASHIRO I; KOMOIKE Y; TAKEDA T; SHIN E; TAKATSUKA Y; KIKKAWA N; MONDEN T; MONDEN M
      P21(WAF1 CIP1) AND P53 PROTEIN EXPRESSION IN BREAST-CANCER/

      American journal of clinical pathology
    73. KAWASAKI M; NOGUCHI M; MORIKAWA A; MATSUNO Y; YAMADA T; HIROHASHI S; KONDO H; SHIMOSATO Y
      NUCLEAR P53 ACCUMULATION BY SMALL-SIZED ADENOCARCINOMAS OF THE LUNG

      Pathology international
    74. OHSAKI Y; TOYOSHIMA E; FUJIUCHI S; MATSUI H; HIRATA S; MIYOKAWA N; KUBO Y; KIKUCHI K
      BCL-2 AND P53 PROTEIN EXPRESSION IN NON-SMALL-CELL LUNG CANCERS - CORRELATION WITH SURVIVAL-TIME

      Clinical cancer research
    75. LJUNGMAN M; ZHANG FF
      BLOCKAGE OF RNA-POLYMERASE AS A POSSIBLE TRIGGER FOR UV LIGHT-INDUCEDAPOPTOSIS

      Oncogene
    76. SKILLING JS; SOOD A; NIEMANN T; LAGER DJ; BULLER RE
      AN ABUNDANCE OF P53 NULL MUTATIONS IN OVARIAN-CARCINOMA

      Oncogene
    77. KUSHIMA R; MULLER W; STOLTE M; BORCHARD F
      DIFFERENTIAL P53 PROTEIN EXPRESSION IN STOMACH ADENOMAS OF GASTRIC AND INTESTINAL PHENOTYPES - POSSIBLE SEQUENCES OF P53 ALTERATION IN STOMACH CARCINOGENESIS

      Virchows Archiv
    78. HESS RD; BRANDNER G
      DNA-DAMAGE BY FILTERED, TAR-FREE AND AEROSOL-FREE CIGARETTE-SMOKE IN RODENT CELLS - A NOVEL EVALUATION

      Toxicology letters
    79. STATTIN P; BERGH A; KARLBERG L; NORDGREN H; DAMBER JE
      P53 IMMUNOREACTIVITY AS PROGNOSTIC MARKET FOR CANCER-SPECIFIC SURVIVAL IN PROSTATE-CANCER

      European urology
    80. EMRICH JG; BENDER H; CLASS R; ESHLEMAN J; MIYAMOTO C; BRADY LW
      IN-VITRO EVALUATION OF IODINE-125-LABELED MONOCLONAL-ANTIBODY (MAB-425) IN HUMAN HIGH-GRADE GLIOMA-CELLS

      American journal of clinical oncology
    81. TANIGUCHI Y; GEMMA A; TAKEDA Y; TAKENAKA K; NIITANI H; KUDOH S; SHIMADA T
      STABILITY OF P53 TUMOR-SUPPRESSOR GENE-MUTATIONS DURING THE PROCESS OF METASTASIS AND DURING CHEMOTHERAPY

      Lung cancer
    82. MUMMENBRAUER T; JANUS F; MULLER B; WIESMULLER L; DEPPERT W; GROSSE F
      P53 PROTEIN EXHIBITS 3'-TO-5' EXONUCLEASE ACTIVITY

      Cell
    83. WEBER F; HALLER O; KOCHS G
      NUCLEOPROTEIN VIRAL-RNA AND MESSENGER-RNA OF THOGOTO VIRUS - A NOVEL CAP-STEALING MECHANISM IN TICK-BORNE ORTHOMYXOVIRUSES

      Journal of virology
    84. GIACHETTI C; CHIN DJ
      INCREASED OLIGONUCLEOTIDE PERMEABILITY IN KERATINOCYTES OF ARTIFICIALSKIN CORRELATES WITH DIFFERENTIATION AND ALTERED MEMBRANE-FUNCTION

      Journal of investigative dermatology
    85. DANDREA E; BAFFA R; MENIN C; MONTAGNA M; RUGGE M; CHIECOBIANCHI L
      TP53 GENE-MUTATIONS IN GASTRIC-CARCINOMA DETECTED BY POLYMERASE CHAIN-REACTION SINGLE-STRAND CONFORMATION POLYMORPHISM ANALYSIS OF ARCHIVALMATERIAL

      Journal of cancer research and clinical oncology
    86. TOP B; MOOI WJ; KLAVER SG; BOERRIGTER L; WISMAN P; ELBERS HRJ; VISSER S; RODENHUIS S
      COMPARATIVE-ANALYSIS OF P53 GENE-MUTATIONS AND PROTEIN ACCUMULATION IN HUMAN NON-SMALL-CELL LUNG-CANCER

      International journal of cancer
    87. APPEL K; SCHNEIDER E; WAGNER P; HOOG JO; MONTENARH M; KARLSSON C
      A NEW 42-KDA PROTEIN-BINDING TO THE GROWTH SUPPRESSOR PROTEIN-P53

      International journal of oncology
    88. PATRY V; ARNAUD E; AMALRIC F; PRATS H
      INVOLVEMENT OF BASIC FIBROBLAST GROWTH-FACTOR NH2 TERMINUS IN NUCLEARACCUMULATION

      Growth factors
    89. HESS R; PLAUMANN B; LUTUM AS; HAESSLER C; HEINZ B; FRITSCHE M; BRANDNER G
      NUCLEAR ACCUMULATION OF P53 IN RESPONSE TO TREATMENT WITH DNA-DAMAGING AGENTS

      Toxicology letters
    90. KIYOKAWA T
      ALTERATION OF P53 IN OVARIAN-CANCER - ITS OCCURRENCE AND MAINTENANCE IN TUMOR PROGRESSION

      International journal of gynecological pathology


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/10/20 alle ore 19:21:05