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La ricerca find articoli where soggetti phrase all words 'NITRIC-OXIDE-SYNTHASE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 11471 riferimenti
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    1. Aliev, G; Smith, MA; Seyidova, D; Neal, ML; Lamb, BT; Nunomura, A; Gasimov, EK; Vinters, HV; Perry, G; LaManna, JC; Friedland, RP
      The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease

      BRAIN PATHOLOGY
    2. Iwai-Kanai, E; Hasegawa, K; Fujita, M; Araki, M; Yanazume, T; Adachi, S; Sasayama, S
      Basic fibroblast growth factor protects cardiac myocytes from iNOS-mediated apoptosis

      JOURNAL OF CELLULAR PHYSIOLOGY
    3. Tzao, C; Nickerson, PA; Russell, JA; Gugino, SF; Steinhorn, RH
      Pulmonary hypertension alters soluble guanylate cyclase activity and expression in pulmonary arteries isolated from fetal lambs

      PEDIATRIC PULMONOLOGY
    4. Huang, H; Martasek, P; Roman, LJ; Silverman, RB
      Synthesis and evaluation of dipeptide amides containing N-omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase

      JOURNAL OF ENZYME INHIBITION
    5. Federico, R; Leone, L; Botta, M; Binda, C; Angelini, R; Venturini, G; Ascenzi, P
      Inhibition of pig liver and Zea mays L. polyamine oxidase: A comparative study

      JOURNAL OF ENZYME INHIBITION
    6. Joyner, MJ; Dietz, NM; Shepherd, JT
      From Belfast to Mayo and beyond: the use and future of plethysmography to study blood flow in human limbs

      JOURNAL OF APPLIED PHYSIOLOGY
    7. Kindig, CA; McDonough, P; Finley, MR; Behnke, BJ; Richardson, TE; Marlin, DJ; Erickson, HH; Poole, DC
      NO inhalation reduces pulmonary arterial pressure but not hemorrhage in maximally exercising horses

      JOURNAL OF APPLIED PHYSIOLOGY
    8. Harada, H; Pavlick, KP; Hines, IN; Hoffman, JM; Bharwani, S; Gray, L; Wolf, RE; Grisham, MB
      Genome and hormones: Gender differences in physiology selected contribution: Effects of gender on reduced-size liver ischemia and reperfusion injury

      JOURNAL OF APPLIED PHYSIOLOGY
    9. Geary, GG; McNeill, AM; Ospina, JA; Krause, DN; Korach, KS; Duckles, SP
      Genome and hormones: Gender differences in physiology - Selected contribution: Cerebrovascular NOS and cyclooxygenase are unaffected by estrogen in mice lacking estrogen receptor-alpha

      JOURNAL OF APPLIED PHYSIOLOGY
    10. Go, YM; Boo, YC; Park, H; Maland, MC; Patel, R; Pritchard, KA; Fujio, Y; Walsh, K; Darley-Usmar, V; Jo, H
      Protein kinase B/Akt activates c-Jun NH2-terminal kinase by increasing NO production in response to shear stress

      JOURNAL OF APPLIED PHYSIOLOGY
    11. Hardy, P; Lamireau, D; Hou, X; Dumont, I; Abran, D; Nuyt, AM; Varma, DR; Chemtob, S
      Major role for neuronal NO synthase in curtailing choroidal blood flow autoregulation in newborn pig

      JOURNAL OF APPLIED PHYSIOLOGY
    12. Levin, ER
      Genome and hormones: Gender differences in physiology - Invited review: Cell localization, physiology, and nongenomic actions of estrogen receptors

      JOURNAL OF APPLIED PHYSIOLOGY
    13. Woodman, CR; Schrage, WG; Rush, JWE; Ray, CA; Price, EM; Hasser, EM; Laughlin, MH
      Hindlimb unweighting decreases endothelium-dependent dilation and eNOS expression in soleus not gastrocnemius

      JOURNAL OF APPLIED PHYSIOLOGY
    14. Lu, GW; Liu, HY
      Downregulation of nitric oxide in the brain of mice during their hypoxic preconditioning

      JOURNAL OF APPLIED PHYSIOLOGY
    15. Liu, YY; Ju, G; Wong-Riley, MTT
      Distribution and colocalization of neurotransmitters and receptors in the pre-Botzinger complex of rats

      JOURNAL OF APPLIED PHYSIOLOGY
    16. Lincoln, TM; Dey, N; Sellak, H
      Signal transduction in smooth muscle - Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression

      JOURNAL OF APPLIED PHYSIOLOGY
    17. Kindig, CA; McDonough, P; Erickson, HH; Poole, DC
      Effect of L-NAME on oxygen uptake kinetics during heavy-intensity exercisein the horse

      JOURNAL OF APPLIED PHYSIOLOGY
    18. Wu, ZX; Maize, DF; Satterfield, BE; Frazer, DG; Fedan, JS; Dey, RD
      Role of intrinsic airway neurons in ozone-induced airway hyperresponsiveness in ferret trachea

      JOURNAL OF APPLIED PHYSIOLOGY
    19. Galan, HL; Regnault, TRH; Le Cras, TD; Tyson, RW; Anthony, RV; Wilkening, RB; Abman, SH
      Cotyledon and binucleate cell nitric oxide synthase expression in an ovinemodel of fetal growth restriction

      JOURNAL OF APPLIED PHYSIOLOGY
    20. Tahawi, Z; Orolinova, N; Joshua, IG; Bader, M; Fletcher, EC
      Physiological and genomic consequences of intermittent hypoxia - Selected contribution: Altered vascular reactivity in arterioles of chronic intermittent hypoxic rats

      JOURNAL OF APPLIED PHYSIOLOGY
    21. Johnson, LR; Rush, JWE; Turk, JR; Price, EM; Laughlin, MH
      Short-term exercise training increases ACh-induced relaxation and eNOS protein in porcine pulmonary arteries

      JOURNAL OF APPLIED PHYSIOLOGY
    22. Laughlin, MH; Pollock, JS; Amann, JF; Hollis, ML; Woodman, CR; Price, EM
      Training induces nonuniform increases in eNOS content along the coronary arterial tree

      JOURNAL OF APPLIED PHYSIOLOGY
    23. Reid, MB
      Invited Review: Redox modulation of skeletal muscle contraction: what we know and what we don't

      JOURNAL OF APPLIED PHYSIOLOGY
    24. Pae, HO; Cho, H; Oh, GS; Kim, NY; Song, EK; Kim, YC; Yun, YG; Kang, CL; Kim, JD; Kim, JM; Chung, HT
      Bakuchiol from Psoralea corylifolia inhibits the expression of inducible nitric oxide synthase gene via the inactivation of nuclear transcription factor-kappa B in RAW 264.7 macrophages

      INTERNATIONAL IMMUNOPHARMACOLOGY
    25. Na, YJ; Jeon, YJ; Suh, JH; Kang, JS; Yang, KH; Kim, HM
      Suppression of IL-8 gene expression by radicicol is mediated through the inhibition of ERK1/2 and p38 signaling and negative regulation of NF-kappa Band AP-1

      INTERNATIONAL IMMUNOPHARMACOLOGY
    26. Ross, R; Reske-Kunz, AB
      The role of NO in contact hypersensitivity

      INTERNATIONAL IMMUNOPHARMACOLOGY
    27. Bidri, M; Feger, F; Varadaradjalou, S; Ben Hamouda, N; Guillosson, JJ; Arock, M
      Mast cells as a source and target for nitric oxide

      INTERNATIONAL IMMUNOPHARMACOLOGY
    28. Chae, HJ; So, HS; Chae, SW; Park, JS; Kim, MS; Oh, JM; Chung, YT; Yang, SH; Jeong, ET; Kim, HM; Park, RK; Kim, HR
      Sodium nitroprusside induces apoptosis of H9C2 cardiac muscle cells in a c-Jun N-terminal kinase-dependent manner

      INTERNATIONAL IMMUNOPHARMACOLOGY
    29. Oh, GS; Pae, HO; Seo, WG; Kim, NY; Pyun, KH; Kim, IK; Shin, M; Chung, HT
      Capsazepine, a vanilloid receptor antagonist, inhibits the expression of inducible nitric oxide synthase gene in lipopolysaccharide-stimulated RAW264.7 macrophages through the inactivation of nuclear transcription factor-kappa

      INTERNATIONAL IMMUNOPHARMACOLOGY
    30. Jeon, YJ; Han, SB; Lee, SH; Kim, HC; Ahn, KS; Kim, HM
      Activation of mitogen-activated protein kinase pathways by angelan in murine macrophages

      INTERNATIONAL IMMUNOPHARMACOLOGY
    31. Dupuis, J
      Mechanisms of acute coronary syndromes and the potential role of statins

      ATHEROSCLEROSIS SUPPLEMENTS
    32. Yoneda, S; Kadowaki, M; Kuramoto, H; Fukui, H; Takaki, M
      Enhanced colonic peristalsis by impairment of nitrergic enteric neurons inspontaneously diabetic rats

      AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
    33. Van Ginneken, C; Van Meir, F; Sys, S; Weyns, A
      Developmental changes in heme-oxygenase-2 and bNOS expression in enteric neurons in the pig duodenum

      AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
    34. Holmberg, K; Steinbusch, HMW; de Vente, J; Hokfelt, T
      Distribution of cGMP in guinea pig autonomic ganglia after stimulation with sodium nitroprusside

      AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
    35. Kurose, T; Ueta, Y; Nomura, M; Yamaguchi, K; Nagata, S
      Nociceptive stimulation increases NO synthase mRNA and vasopressin heteronuclearRNA in the rat paraventricular nucleus

      AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
    36. Johns, DG; Dorrance, AM; Tramontini, NL; Webb, RC
      Glucocorticoids inhibit tetrahydrobiopterin-dependent endothelial function

      EXPERIMENTAL BIOLOGY AND MEDICINE
    37. Croy, BA; Linder, KE; Yager, JA
      Primer for non-immunologists on immune-deficient mice and their applications in research

      COMPARATIVE MEDICINE
    38. Aoyama, Y; Kato, C; Sakakibara, S
      Expression of metallothionein in the liver and kidney of rats is influenced by excess dietary histidine

      COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
    39. Flodin, MF
      Macrophages and possible osteoclast differentiation in the rat bullar boneduring experimental acute otitis media, with reference to tympanosclerosis

      OTOLOGY & NEUROTOLOGY
    40. Ohteki, T; Suzue, K; Maki, C; Ota, T; Koyasu, S
      Critical role of IL-15-IL-15R for antigen-presenting cell functions in theinnate immune response

      NATURE IMMUNOLOGY
    41. Rao, CV; Alsip, NL
      Use of the rat model to study hCG/LH effects on uterine blood flow

      SEMINARS IN REPRODUCTIVE MEDICINE
    42. Hegyi, L; Hardwick, SJ; Siow, RCM; Skepper, JN
      Macrophage death and the role of apoptosis in human atherosclerosis

      JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
    43. Zaveri, NT
      Synthesis of a 3,4,5-trimethoxybenzoyl ester analogue of epigallocatechin-3-gallate (EGCG): A potential route to the natural product green tea catechin, EGCG

      ORGANIC LETTERS
    44. Reilly, CM; Oates, JC; Sudian, J; Crosby, MB; Halushka, PV; Gilkeson, GS
      Prostaglandin J(2) inhibition of mesangial cell iNOS expression

      CLINICAL IMMUNOLOGY
    45. Rosignoli, F; Goren, NB; Leiros, CP
      Alterations in nitric oxide synthase activity and expression in submandibular glands of NOD mice

      CLINICAL IMMUNOLOGY
    46. Haegeli, L; Quitzau, K; Luscher, TF
      From endothelial dysfunction to clinical events - Concept and update on the ENCORE trials

      EUROPEAN HEART JOURNAL SUPPLEMENTS
    47. Keegan, A; Cotter, MA; Cameron, NE
      Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    48. Rosen, P; Nawroth, PP; King, G; Moller, W; Tritschler, HJ; Packer, L
      The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN,the American Diabetes Association and the German Diabetes Society

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    49. Everett, SA; Naylor, MA; Stratford, MRL; Patel, KB; Ford, E; Mortensen, A; Ferguson, AC; Vojnovic, B; Wardman, P
      Iminoxyl radicals and stable products from the one-electron oxidation of 1-methylindole-3-carbaldehyde oximes

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
    50. Chancellor, MB; Yoshimura, N; Pruchnic, R; Huard, J
      Gene therapy strategies for urological dysfunction

      TRENDS IN MOLECULAR MEDICINE
    51. Galbiati, F; Razani, B; Lisanti, MP
      Caveolae and caveolin-3 in muscular dystrophy

      TRENDS IN MOLECULAR MEDICINE
    52. Quarck, R; Holvoet, P
      Restenosis and gene therapy

      EXPERT OPINION ON BIOLOGICAL THERAPY
    53. Russell, DG
      Mycobacterium tuberculosis: Here today, and here tomorrow

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    54. Scheid, MP; Woodgett, JR
      PKB/AKT: Functional insights from genetic models

      NATURE REVIEWS MOLECULAR CELL BIOLOGY
    55. Beal, MF
      Experimental models of Parkinson's disease

      NATURE REVIEWS NEUROSCIENCE
    56. Cleveland, DW; Rothstein, JD
      From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS

      NATURE REVIEWS NEUROSCIENCE
    57. Drumm, ML
      Modifier genes and variation in cystic fibrosis

      RESPIRATORY RESEARCH
    58. Hele, DJ; Yacoub, MH; Belvisi, MG
      The heterotopic tracheal allograft as an animal model of obliterative bronchiolitis

      RESPIRATORY RESEARCH
    59. Seo, KK; Kim, SC; Jun, IO; Oh, MM; Lee, MY
      Synergistic effects of sildenafil on relaxation of rabbit and rat cavernosal smooth muscles when combined with various vasoactive agents

      BJU INTERNATIONAL
    60. Baltaci, S; Orhan, D; Gogus, C; Turkolmez, K; Tulunay, O; Gogus, O
      Inducible nitric oxide synthase expression in benign prostatic hyperplasia, low- and high-grade prostatic intraepithelial neoplasia and prostatic carcinoma

      BJU INTERNATIONAL
    61. Sullivan, ME; Keoghane, SR; Miller, MAW
      Vascular risk factors and erectile dysfunction

      BJU INTERNATIONAL
    62. Fujisawa, M; Yamanaka, K; Tanaka, H; Tanaka, H; Okada, H; Arakawa, S; Kamidono, S
      Expression of endothelial nitric oxide synthase in the Sertoli cells of men with infertility of various causes

      BJU INTERNATIONAL
    63. Blackwell, JM; Goswami, T; Evans, CAW; Sibthorpe, D; Papo, N; White, JK; Searle, S; Miller, EN; Peacock, CS; Mohammed, H; Ibrahim, M
      SLC11A1 (formerly NRAMP1) and disease resistance

      CELLULAR MICROBIOLOGY
    64. Vaccari, A; Ruiu, S; Saba, P; Fa, M; Cagiano, R; Coluccia, A; Mereu, G; Steardo, L; Tattoli, M; Trabace, L; Cuomo, V
      Prenatal low-level exposure to CO alters postnatal development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats

      INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
    65. Chen, G; Huang, LD; Zeng, WZ; Manji, HK
      Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: long-term effects on cell survival and transcript stability

      INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
    66. Tsukahara, Y; Morisaki, T; Kojima, M; Uchiyama, A; Tanaka, M
      iNOS expression by activated neutrophils from patients with sepsis

      ANZ journal of surgery
    67. Schroppel, K; Kryk, M; Herrmann, M; Leberer, E; Rollinghoff, M; Bogdan, C
      Suppression of type 2 NO-synthase activity in macrophages by Candida albicans

      INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
    68. Hierholzer, C; Billiar, TR
      Molecular mechanisms in the early phase of hemorrhagic shock

      LANGENBECKS ARCHIVES OF SURGERY
    69. Muehlhauser, F; Liebl, U; Kuehl, S; Walter, S; Bertsch, T; Fassbender, K
      Aggregation-dependent interaction of the Alzheimer's beta-amyloid and microglia

      CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    70. Walter, R; Kaufmann, PA; Buck, A; Berthold, T; Wyss, C; von Schulthess, GK; Schaffner, A; Schoedon, G
      Tetrahydrobiopterin increases myocardial blood flow in healthy volunteers:a double-blind, placebo-controlled study

      SWISS MEDICAL WEEKLY
    71. Manning, PT; Thompson, JM; Currie, MG
      Selective iNOS inhibitors

      NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
    72. Abdallahi, OMS; Bensalem, H; Augier, R; Diagana, M; De Reggi, M; Gharib, B
      Arginase expression in peritoneal macrophages and increase in circulating polyamine levels in mice infected with Schistosoma mansoni

      CELLULAR AND MOLECULAR LIFE SCIENCES
    73. Horvat, A; Nikezie, G; Petrovic, S; Kanazir, DT
      Binding of estradiol to synaptosomal mitochondria: physiological significance

      CELLULAR AND MOLECULAR LIFE SCIENCES
    74. Bing, RJ
      Some aspects of biochemistry of myocardial infarction

      CELLULAR AND MOLECULAR LIFE SCIENCES
    75. Akbar, S; Minor, T
      Significance and molecular targets of protein kinase A during cAMP-mediated protection of cold stored liver grafts

      CELLULAR AND MOLECULAR LIFE SCIENCES
    76. Sarkar, D; Vallance, P; Harding, SE
      Nitric oxide: not just a negative inotrope

      EUROPEAN JOURNAL OF HEART FAILURE
    77. Surh, YJ; Chun, KS; Cha, HH; Han, SS; Keum, YS; Park, KK; Lee, SS
      Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppressionof NF-kappa B activation

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    78. Garrett, IR; Gutierrez, G; Mundy, GR
      Statins and bone formation

      CURRENT PHARMACEUTICAL DESIGN
    79. Gomariz, RP; Martinez, C; Abad, C; Leceta, J; Delgado, M
      Immunology of VIP: A review and therapeutical perspectives

      CURRENT PHARMACEUTICAL DESIGN
    80. Ozturk, Y
      Kinin receptors and their antagonists as novel therapeutic agents

      CURRENT PHARMACEUTICAL DESIGN
    81. Laurer, HL; McIntosh, TK
      Pharmacologic therapy in traumatic brain injury: Update on experimental treatment strategies

      CURRENT PHARMACEUTICAL DESIGN
    82. Rodriguez-Tellez, M; Arguelles, F; Herrerias, JM; Ledro, D; Esteban, J; Herrerias, JM
      Antiinflamatory agents less dangerous for gastrointestinal tract

      CURRENT PHARMACEUTICAL DESIGN
    83. Lanas, A; Santolaria, S
      Gastroesophageal reflux disease (GERD): Current agents and future perspective

      CURRENT PHARMACEUTICAL DESIGN
    84. Takeuchi, K; Tanaka, A; Suzuki, K; Mizoguchi, H
      Gastrointestinal sparing anti-inflammatory drugs - Effects on ulcerogenic and healing responses

      CURRENT PHARMACEUTICAL DESIGN
    85. Shtrichman, R; Samuel, CE
      The role of gamma interferon in antimicrobial immunity

      CURRENT OPINION IN MICROBIOLOGY
    86. Harris, DL
      High-valent intermediates of heme proteins and model compounds

      CURRENT OPINION IN CHEMICAL BIOLOGY
    87. McLachlin, DT; Chait, BT
      Analysis of phosphorylated proteins and peptides by mass spectrometry

      CURRENT OPINION IN CHEMICAL BIOLOGY
    88. Shochina, M; Fellig, Y; Sughayer, M; Pizov, G; Vitner, K; Podeh, D; Hochberg, A; Ariel, I
      Nitric oxide synthase immunoreactivity in human bladder carcinoma

      JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
    89. Yoshida, M; Sagawa, N; Itoh, H; Yura, S; Korita, D; Kakui, K; Hirota, N; Sato, T; Ito, A; Fujii, S
      Nitric oxide increases matrix metalloproteinase-1 production in human uterine cervical fibroblast cells

      MOLECULAR HUMAN REPRODUCTION
    90. Lahiri, S; Rozanov, C; Roy, A; Storey, B; Buerk, DG
      Regulation of oxygen sensing in peripheral arterial chemoreceptors

      INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    91. Ishii, M; Shimizu, S; Nagai, T; Shiota, K; Kiuchi, Y; Yamamoto, T
      Stimulation of tetrahydrobiopterin synthesis induced by insulin: possible involvement of phosphatidylinositol 3-kinase

      INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    92. Bailey, CL; Channick, RN; Rubin, LJ
      A new era in the treatment of primary pulmonary hypertension

      HEART
    93. Kim, HT; Qiang, WN; Wong, PKY; Stoica, G
      Enhanced proteolysis of I kappa B alpha and I kappa B beta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: A potential mechanism of NF-kappa B activation

      JOURNAL OF NEUROVIROLOGY
    94. Albright, AV; Martin, J; O'Connor, M; Gonzalez-Scarano, F
      Interactions between HIV-1 gp120, chemokines, and cultured adult microglial cells

      JOURNAL OF NEUROVIROLOGY
    95. Si, ML; Al-Sharafi, B; Lai, CC; Khardori, R; Chang, CS; Su, CY
      Gender difference in cytoprotection induced by estrogen on female and malebovine aortic endothelial cells

      ENDOCRINE
    96. Valdes, G; Chacon, C; Corthorn, J; Figueroa, CD; Germain, AM
      Tissue kallikrein in human placenta in early and late gestation

      ENDOCRINE
    97. Anel, RL; Kumar, A
      Experimental and emerging therapies for sepsis and septic shock

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    98. Barton, M
      Postmenopausal oestrogen replacement therapy and atherosclerosis: can current compounds provide cardiovascular protection?

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    99. Maestroni, GJM
      The immunotherapeutic potential of melatonin

      EXPERT OPINION ON INVESTIGATIONAL DRUGS
    100. Sheehy, N; Vaughan, CJ; Delanty, N
      Statins and neuroprotection

      EXPERT OPINION ON INVESTIGATIONAL DRUGS


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/05/20 alle ore 12:43:53