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Expression levels of the nerve growth factor receptors TrkA and p75 in effusions and solid tumors of serous ovarian carcinoma patients
CLINICAL CANCER RESEARCH
Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): Mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor
HUMAN MUTATION
Congenital insensitivity to pain with anhidrosis (CIPA): Novel mutations of the TRK4 (NTRK1) gene, a putative uniparental disomy, and a linkage of the mutant TRKA and PKLR genes in a family with CIPA and pyruvate kinase deficiency
HUMAN MUTATION
The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease
MOLECULAR AND CELLULAR NEUROSCIENCE
Expression of Trk tyrosine kinase receptor is a biologic marker for cell proliferation and perineural invasion of human pancreatic ductal adenocarcinoma
ONCOLOGY REPORTS
Congenital insensitivity to pain with anhidrosis (CIPA): effect of TRKA (NTRK1) missense mutations on autophosphorylation of the receptor tyrosine kinase for nerve growth factor
HUMAN MOLECULAR GENETICS
NMDA receptor subunits are phosphorylated by activation of neurotrophin receptors in PSD of rat spinal cord
NEUROREPORT
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
CURRENT OPINION IN NEUROBIOLOGY
Heat shock protein 90 in retinal ganglion cells: Association with axonallytransported proteins
VISUAL NEUROSCIENCE
mKlf7, a potential transcriptional regulator of TrkA nerve growth factor receptor expression in sensory and sympathetic neurons
DEVELOPMENT
Autocrine expression of neurotrophins and their receptors in prostate cancer
INTERNATIONAL JOURNAL OF UROLOGY
Purification, crystallization and preliminary X-ray analysis of the Fab fragment from MNAC13, a novel antagonistic anti-tyrosine kinase A receptor monoclonal antibody
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
Reduced number of functional glutamatergic synapses in hippocampal neuronsoverexpressing full-length TrkB receptors
JOURNAL OF NEUROSCIENCE RESEARCH
TrkB dimerization during development of the prefrontal cortex of the macaque
JOURNAL OF NEUROSCIENCE RESEARCH
The role of neurotrophins in the pathogenesis of allergic asthma
ALLERGOLOGIE
Nerve growth factor and neurotrophin-3 promote chemotaxis of mouse macrophages in vitro
NEUROSCIENCE LETTERS
Trk receptor tyrosine kinases: A bridge between cancer and neural development
CANCER LETTERS
Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a Src kinase pathway
MOLECULAR AND CELLULAR BIOLOGY
Macrophages express neurotrophins and neurotrophin receptors - Regulation of nitric oxide production by NT-3
JOURNAL OF NEUROIMMUNOLOGY
Target specific differentiation of peripheral trigeminal axons in rat-chick chimeric explant cocultures
DEVELOPMENTAL BRAIN RESEARCH
Immobilization stress rapidly and differentially modulates BDNF and TrkB mRNA expression in the pituitary gland of adult male rats
NEUROENDOCRINOLOGY
Rapid stimulatory effects of brain-derived neurotrophic factor and neurotrophin-3 on somatostatin release and intracellular calcium rise in primary hypothalamic cell cultures
NEUROENDOCRINOLOGY
p75 co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains
JOURNAL OF BIOLOGICAL CHEMISTRY
Signaling for activity-dependent inhibitory synaptogenesis via the TrkB receptor
EXPERIMENTAL NEUROLOGY
Distribution of the neurotrophin receptors p75 and trkB in peripheral mechanoreceptors; observations on changes after injury
EXPERIMENTAL BRAIN RESEARCH
Gestational changes in calcitonin gene-related peptide, nerve growth factor, and its receptors in rat dorsal root ganglia
BIOLOGY OF REPRODUCTION
Female steroid hormones modulate receptors for nerve growth factor in rat dorsal root ganglia
BIOLOGY OF REPRODUCTION
TrkA and TrkB neurotrophin receptor immunoreactivity in the teleost (Scorpaena porcus) endocrine pancreas
ANATOMICAL RECORD
Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection
JOURNAL OF NEUROVIROLOGY
Nitric oxide activation of TrkB through peroxynitrite
NEUROREPORT
Differential somato-dendritic localization of TrkA, TrkB, TrkC and p75 mRNAs in vivo
NEUROREPORT
Regulation of NGF-family ligands and receptors in adulthood and senescence: correlation to degenerative and regenerative changes in cutaneous innervation
EUROPEAN JOURNAL OF NEUROSCIENCE
The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase thattransforms NIH3T3 cells
ONCOGENE
The protein tyrosine kinase family of the human genome
ONCOGENE
Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons
NEURON
Intracerebroventricular infusion of CHO5, a rat monoclonal antibody directed against mouse low-affinity nerve growth factor receptor (p75NTR), specifically labels basal forebrain cholinergic neurons in mouse brain
METABOLIC BRAIN DISEASE
TrkC expression predicts good clinical outcome in primitive neuroectodermal brain tumors
JOURNAL OF CLINICAL ONCOLOGY
Retinoic acid potentiated the protective effect of NGF against staurosporine-induced apoptosis in cultured chick neurons by increasing the trkA protein expression
JOURNAL OF NEUROSCIENCE RESEARCH
Association of the abl tyrosine kinase with the Trk nerve growth factor receptor
JOURNAL OF NEUROSCIENCE RESEARCH
Neurotrophic and cell-cell dependent control of early follicular development
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Changes in the expression of the nerve growth factor receptors TrkA and p75(LNGR) in the rat thymus with ageing and increased nerve growth factor plasma levels
CELL AND TISSUE RESEARCH
Expression of nerve growth factor and its receptors in the somatosensory-motor cortex of Macaca nemestrina
JOURNAL OF NEUROCYTOLOGY
Identification and characterization of an activating TrkA deletion mutation in acute myeloid leukemia
MOLECULAR AND CELLULAR BIOLOGY
Trk C signaling is required for retinal progenitor cell proliferation
JOURNAL OF NEUROSCIENCE
NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking
JOURNAL OF NEUROSCIENCE
Neurotrophins induce death of hippocampal neurons via the p75 receptor
JOURNAL OF NEUROSCIENCE
Identification of novel trkA variants with deletions in leucine-rich motifs of the extracellular domain
JOURNAL OF NEUROIMMUNOLOGY
Tissue disposition and pharmacokinetics of recombinant human nerve growth factor after acute and chronic subcutaneous administration in monkeys
DRUG METABOLISM AND DISPOSITION
Glial cells as targets and producers of neurotrophins
INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL. 197
Sex- and age-related P75 neurotrophin receptor expression in the human supraoptic nucleus
NEUROENDOCRINOLOGY
Design and solution structure of functional peptide mimetics of nerve growth factor
JOURNAL OF MEDICINAL CHEMISTRY
Epithelial rests of Malassez express immunoreactivity of TrkA and its distribution is regulated by sensory nerve innervation
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
Activation of TrkA tyrosine kinase in embryonal carcinoma cells promotes cell compaction, independently of tyrosine phosphorylation of catenins
JOURNAL OF CELL SCIENCE
TrkA amino acids controlling specificity for nerve growth factor
JOURNAL OF BIOLOGICAL CHEMISTRY
Expression of Trk isoforms in brain regions and in the striatum of patients with Alzheimer's disease
EXPERIMENTAL NEUROLOGY
Alterations in TrkA, TrkB and TrkC receptor immunoreactivities in parietalcortex and cerebellum in Alzheimer's disease
EUROPEAN NEUROLOGY
Molecular cues for the development of adrenal chromaffin cells and their preganglionic innervation
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
Dynamic expression of neurotrophin receptors during sensory neuron genesisand differentiation
DEVELOPMENTAL BIOLOGY
Astrocytes contribute to the brain-metastatic specificity of melanoma cells by producing heparanase
CANCER RESEARCH
Effects of deprivation of neonatal nerve growth factor on the expression of neurotrophin receptors and brain-derived neurotrophic factor by dental pulp afferents of the adult rat
ARCHIVES OF ORAL BIOLOGY
Expression of p75(LNGFR) and Trk neurotrophin receptors in normal and neoplastic human prostate
BJU INTERNATIONAL
Synthetic process development of antitumor agent KT6587, an indolocarbazole alkaloid K252a derivative
ORGANIC PROCESS RESEARCH & DEVELOPMENT
NGF activates similar intracellular signaling pathways in vascular smooth muscle cells as PDGF-BB but elicits different biological responses
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Competition for neurotrophic factor in the development of nerve connections
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
Neurotrophic factors modulate hair cells and their potassium currents in chick otocyst explants
EUROPEAN JOURNAL OF NEUROSCIENCE
Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells
ONCOGENE
Heterogeneous localizations of Trk B among individual periodontal Ruffini endings in the rat incisor
ARCHIVES OF HISTOLOGY AND CYTOLOGY
Differential expression of NGF receptors in human thymic epithelial tumors
PATHOLOGY RESEARCH AND PRACTICE
Neurotrophins and neurotrophin receptors in some neural crest-derived tumours (ganglioneuroma, phaeochromocytoma and paraganglioma)
HISTOPATHOLOGY
Co-localization of the glial cell-line derived neurotrophic factor and itsfunctional receptor c-RET in a subpopulation of rat dorsal root ganglion neurons
NEUROSCIENCE LETTERS
Trks and p75 genes are differentially expressed in the inner ear of human embryos. What may Trks and p75 null mutant mice suggest on human development?
NEUROSCIENCE LETTERS
Gangliosides and growth factor receptor regulation
BIOCHEMICAL SOCIETY TRANSACTIONS
Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: Induction of caspase-dependent cell death and activation of NF-kappa B
JOURNAL OF NEUROSCIENCE
Cholinergic septal afferent terminals preferentially contact neuropeptide Y-containing interneurons compared to parvalbumin-containing interneurons in the rat dentate gyrus
JOURNAL OF NEUROSCIENCE
Growth factors and taurine protect against excitotoxicity by stabilizing calcium homeostasis and energy metabolism
JOURNAL OF NEUROSCIENCE
Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons
JOURNAL OF NEUROSCIENCE
A role for the POU-III transcription factor Brn-4 in the regulation of striatal neuron precursor differentiation
EMBO JOURNAL
Mitogenesis in glioblastoma multiforme cell lines: A role for NGF and its TrkA receptors
JOURNAL OF NEURO-ONCOLOGY
Novel mechanisms of estrogen action in the brain: New players in an old story
FRONTIERS IN NEUROENDOCRINOLOGY
Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
NATURE
Trophic regulation of synaptic plasticity
JOURNAL OF NEUROBIOLOGY
Nerve growth factor protects human keratinocytes from ultraviolet-B-induced apoptosis
JOURNAL OF INVESTIGATIVE DERMATOLOGY
p75(NTR) immunoreactivity in the rat dentate gyrus is mostly within presynaptic profiles but is also found in some astrocytic and postsynaptic profiles
JOURNAL OF COMPARATIVE NEUROLOGY
Expression of trkB and trkC mRNAs by adult midbrain dopamine neurons: A double-label in situ hybridization study
JOURNAL OF COMPARATIVE NEUROLOGY
Neural precursor differentiation following transplantation into neocortex is dependent on intrinsic developmental state and receptor competence
EXPERIMENTAL NEUROLOGY
Biological actions of nerve growth factor in the peripheral nervous system
EUROPEAN NEUROLOGY
Sustained in vivo regression of dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555)
CANCER RESEARCH
Congenital insensitivity to pain with anhidrosis: Novel mutations in the TRKA (NTRK1) gene encoding a high-affinity receptor for nerve growth factor
AMERICAN JOURNAL OF HUMAN GENETICS
CYSTIC NEUROBLASTOMA - EMPHASIS ON GENE-EXPRESSION, MORPHOLOGY, AND PATHOGENESIS
PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
Increased levels of TrkA in the regenerating retinal ganglion cells of fish
NEUROREPORT
IMMUNOHISTOCHEMICAL LOCALIZATION OF NEUROTROPHINS AND NEUROTROPHIN RECEPTORS IN HUMAN AND MOUSE SALIVARY-GLANDS
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
Neurons derived in vitro from ES cells express homeoproteins characteristic of motoneurons and interneurons
MECHANISMS OF DEVELOPMENT
NGF, BDNF, NT3, NT4 AND GDNF IN TOOTH DEVELOPMENT
European journal of oral sciences
NGF content in the cerebral cortex of non-demented patients with amyloid-plaques and in symptomatic Alzheimer's disease
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
Frequent detection of TrkA expression in human neuroblastoma cell lines
ACTA PAEDIATRICA JAPONICA
FUNCTIONAL EXPRESSION OF TRKA RECEPTORS IN HIPPOCAMPAL-NEURONS
Journal of neuroscience research
GENERATION AND CHARACTERIZATION OF EMBRYONIC STRIATAL CONDITIONALLY IMMORTALIZED ST14A CELLS
Journal of neuroscience research
DISTINCT POPULATIONS OF MACROPHAGES IN THE ADULT-RAT ADRENAL-GLAND - A SUBPOPULATION WITH NEUROTROPHIN-4-LIKE IMMUNOREACTIVITY
Cell and tissue research
EXPRESSION OF FIBROBLAST GROWTH-FACTOR RECEPTOR IN ADULT-MOUSE UTRICLE DAMAGED BY STREPTOMYCIN SULFATE
ORL
COMPETITIVE SIGNALING BETWEEN TRKA AND P75 NERVE GROWTH-FACTOR RECEPTORS DETERMINES CELL-SURVIVAL
The Journal of neuroscience