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La ricerca find articoli where soggetti phrase all words 'NEOCARZINOSTATIN' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 377 riferimenti
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    1. Cramer, CJ; Kormos, BL; Seierstad, M; Sherer, EC; Winget, P
      Biradical and zwitterionic cyclizations of oxy-substituted enyne-allenes

      ORGANIC LETTERS
    2. Dillinger, S; Bertus, P; Pale, P
      First evidence for the use of organosilver compounds in Pd-catalyzed coupling reactions; A mechanistic rationale for the Pd/Ag-catalyzed enyne synthesis?

      ORGANIC LETTERS
    3. Villiers, P; Vicart, N; Ramondenc, Y; Ple, G
      1,6-dibromohexa-1,3,5-triene - Stereocontrolled synthesis of monosubstituted and disubstituted hexatrienes by palladium-catalysed cross-coupling reactions

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    4. Bertus, P; Halbes, U; Pale, P
      Pd/Ag-catalyzed direct coupling of 1-trimethylsilyl alkynes with vinyl triflates

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    5. Lear, MJ; Yoshimura, F; Hirama, M
      A direct and efficient alpha-selective glycosylation protocol for the kedarcidin sugar, L-mycarose: AgPF6 as a remarkable activator of 2-deoxythioglycosides

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    6. Schmittel, M; Maywald, M
      Electronic effects in the thermal C-2-C-6 biradical cyclisation of enyne-allenes

      CHEMICAL COMMUNICATIONS
    7. Cramer, CJ; Thompson, J
      Quantum chemical characterization of singlet and triplet didehydroindenes

      JOURNAL OF PHYSICAL CHEMISTRY A
    8. Quada, JC; Boturyn, D; Hecht, SM
      Photoactivated DNA cleavage by compounds structurally related to the bithiazole moiety of bleomycin

      BIOORGANIC & MEDICINAL CHEMISTRY
    9. Zhou, QB; Pande, P; Johnson, AE; Rokita, SE
      Sequence-specific delivery of a quinone methide intermediate to the major groove of DNA

      BIOORGANIC & MEDICINAL CHEMISTRY
    10. Lin, CF; Hsieh, PC; Lu, WD; Chiu, HF; Wu, MJ
      A series of enediynes as novel inhibitors of topoisomerase I

      BIOORGANIC & MEDICINAL CHEMISTRY
    11. Izadi-Pruneyre, N; Quiniou, E; Blouquit, Y; Perez, J; Minard, P; Desmadril, M; Mispelter, J; Adjadj, E
      Key interactions in the immunoglobulin-like structure of apo-neocarzinostatin: Evidence from nuclear magnetic resonance relaxation data and moleculardynamics simulations

      PROTEIN SCIENCE
    12. Nakatani, K; Sando, S; Yoshida, K; Saito, I
      Specific binding of 2-amino-1,8-naphthyridine into a single guanine bulge as evidenced by photooxidation of GG doublet

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
    13. Abe, S; Yamasaki, T; Nakano, K; Yoshikawa, I; Tabaru, A; Otsuki, M
      Multiple hepatic infarction after transcatheter arterial infusion with SMANCS

      JOURNAL OF GASTROENTEROLOGY
    14. Smyth, GD; Ohmura, H; Mikami, K
      Intramolecular oxonium-ene-type reaction of a bis(alkyne-dicobalt hexacarbonyl) complex

      SYNLETT
    15. Kren, V; Martinkova, L
      Glycosides in medicine: "The role of glycosidic residue in biological activity"

      CURRENT MEDICINAL CHEMISTRY
    16. Lopez-Larraza, DM; Moore, K; Dedon, PC
      Thiols alter the partitioning of calicheamicin-induced deoxyribose 4 '-oxidation reactions in the absence of DNA radical repair

      CHEMICAL RESEARCH IN TOXICOLOGY
    17. Angeloff, A; Dubey, I; Pratviel, G; Bernadou, J; Meunier, B
      Characterization of a 5 '-aldehyde terminus resulting from the oxidative attack at C5 ' of a 2-deoxyribose on DNA

      CHEMICAL RESEARCH IN TOXICOLOGY
    18. Suzuki, I; Shigenaga, A; Nemoto, H; Shibuya, M
      Acid-catalyzed cycloaromatization of enediyne model compounds via enyne-allene intermediates

      HETEROCYCLES
    19. Numata, K; Tanaka, K; Kiba, T; Matsumoto, S; Iwase, S; Hara, K; Kirikoshi, H; Morita, K; Saito, S; Sekihara, H
      Nonresectable hepatocellular carcinoma: Improved percutaneous ethanol injection therapy guided by CO2-enhanced sonography

      AMERICAN JOURNAL OF ROENTGENOLOGY
    20. Berthet, N; Roupioz, Y; Constant, JF; Kotera, M; Lhomme, J
      Translesional synthesis on DNA templates containing the 2 '-deoxyribonolactone lesion

      NUCLEIC ACIDS RESEARCH
    21. Arulmozhiraja, S; Sato, T; Yabe, A
      Benzdiynes revisited: Ab initio and density functional theory

      JOURNAL OF COMPUTATIONAL CHEMISTRY
    22. Maeda, H
      SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy

      ADVANCED DRUG DELIVERY REVIEWS
    23. Maeda, H; Sawa, T; Konno, T
      Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS

      JOURNAL OF CONTROLLED RELEASE
    24. Burlison, JA; Gray, JM; Young, DGJ
      Metathesis in the presence of a transition metal alkyne complex

      TETRAHEDRON LETTERS
    25. Sasaki, T; Inoue, M; Hirama, M
      Synthetic studies toward C-1027 chromophore: construction of a highly unsaturated macrocycle

      TETRAHEDRON LETTERS
    26. Dai, WM; Wu, AX
      First synthesis of a highly strained cyclodeca-1,5-diyne skeleton via intramolecular Sonogashira cross-coupling

      TETRAHEDRON LETTERS
    27. Caddick, S; Cheung, S; Doyle, VE; Frost, LM; Soscia, MG; Delisser, VM; Williams, MRV; Etheridge, ZC; Khan, S; Hitchcock, PB; Pairaudeau, G; Vile, S
      Stereoselective synthesis of polyfunctionalised hydroxylated cyclopentanesfrom dihydroxylated 2-cyclopentenone derivatives

      TETRAHEDRON
    28. Nakatani, K; Saito, I
      Sequence selectivity for the guanine alkylation by DNA alkylating intercalators

      JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN
    29. Wang, GX; Iguchi, S; Hirama, M
      A very concise and stereoselective synthesis of 3-substituted cis-hex-3-ene-1,5-diyne and corresponding epoxydiyne

      JOURNAL OF ORGANIC CHEMISTRY
    30. Tanaka, T; Fukuda-Ishisaka, S; Hirama, M; Otani, T
      Solution structures of C-1027 apoprotein and its complex with the aromatized chromophore

      JOURNAL OF MOLECULAR BIOLOGY
    31. Perez, J; Vachette, P; Russo, D; Desmadril, M; Durand, D
      Heat-induced unfolding of neocarzinostatin, a small all-beta protein investigated by small-angle X-ray scattering

      JOURNAL OF MOLECULAR BIOLOGY
    32. Hiraku, Y; Oikawa, S; Kuroki, K; Sugiyama, H; Saito, I; Kawanishi, S
      Amplification of bleomycin-induced DNA cleavage at cytosine residues 3 ' to GGG sequences by pyrrole triamide

      BIOCHEMICAL PHARMACOLOGY
    33. Kobayashi, S; Ashizawa, S; Takahashi, Y; Sugiura, Y; Nagaoka, M; Lear, MJ; Hirama, M
      The first total synthesis of N1999-A2: Absolute stereochemistry and stereochemical implications into DNA cleavage

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    34. Kobayashi, S; Reddy, RS; Sugiura, Y; Sasaki, D; Miyagawa, N; Hirama, M
      Investigation of the total synthesis of N1999-A2: Implication of stereochemistry

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    35. Hurley, AL; Mohler, DL
      Organometallic photonucleases: Synthesis and DNA-cleavage studies of cyclopentadienyl metal-substituted dendrimers designed to increase double-strandscission

      ORGANIC LETTERS
    36. Ansorge, M; Polborn, K; Muller, TJJ
      The ferrocenyldiphenylpropargyl cation - A spectroscopic comparison among stabilizing substituents and nucleophilic additions

      EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
    37. Gorth, FC; Rucker, M; Eckhardt, M; Bruckner, R
      Decagram-scale synthesis of the neocarzinostatin carboxylic acid

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    38. Myers, AG; Goldberg, SD
      Synthesis of the kedarcidin core structure by a transannular cyclization pathway

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    39. Debbert, SL; Cramer, CJ
      Systematic comparison of the benzynes, pyridynes, and pyridynium cations and characterization of the Bergman cyclization of Z-but-1-en-3-yn-1-yl isonitrile to the meta diradical 2,4-pyridyne

      INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
    40. van Duijn-Goedhart, A; Zdzienicka, MZ; Sankaranarayanan, K; van Buul, PPW
      Differential responses of Chinese hamster mutagen sensitive cell lines to low and high concentrations of calicheamicin and neocarzinostatin

      MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
    41. Mispelter, J; Izadi-Pruneyre, N; Quiniou, E; Adjadj, E
      Simple and accurate determination of global tau(R) in proteins using C-13 or N-15 relaxation data

      JOURNAL OF MAGNETIC RESONANCE
    42. Ordoukhanian, P; Taylor, JS
      Caged single and double strand breaks

      BIOCONJUGATE CHEMISTRY
    43. Schor, NF; Rudin, CM; Hartman, AR; Thompson, CB; Tyurina, YY; Kagan, VE
      Cell line dependence of Bcl-2-induced alteration of glutathione handling

      ONCOGENE
    44. Ikeda, K; Saitoh, S; Kobayashi, M; Suzuki, Y; Suzuki, F; Tsubota, A; Arase, Y; Chayama, K; Murashima, N; Kumada, H
      Hepatic vascular side effects of styrene maleic acid neocarzinostatin in the treatment of hepatocellular carcinoma

      JOURNAL OF GASTROENTEROLOGY
    45. Okada, S
      How can we avert hepatic vascular complications in SMANCS therapy for hepatocellular carcinoma?

      JOURNAL OF GASTROENTEROLOGY
    46. Abe, S; Okubo, Y; Ejiri, Y; Kume, K; Otsuki, M
      Focal therapeutic efficacy of transcatheter arterial infusion of styrene maleic acid neocarzinostatin for hepatocellular carcinoma

      JOURNAL OF GASTROENTEROLOGY
    47. Suffert, J; Raeppel, S; Raeppel, F; Didier, B
      Straightforward access to [6]metacyclophene-based enynes by an inter-intramolecular tandem etherification through a one-pot double SNAr reaction

      SYNLETT
    48. Khan, S; Kato, N; Hirama, M
      Stereoselective synthesis of functionalized (Z)-keto-enyne and its epoxide

      SYNLETT
    49. Rothchild, R; Sapse, AM; Balkova, A; Lown, JW
      Ab initio calculations on (-)-calicheamicinone and some of its reactions involved in its activation and interaction with DNA

      JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
    50. Harsch, A; Marzilli, LA; Bunt, RC; Stubbe, J; Vouros, P
      Accurate and rapid modeling of iron-bleomycin-induced DNA damage using tethered duplex oligonucleotides and electrospray ionization ion trap mass spectrometric analysis

      NUCLEIC ACIDS RESEARCH
    51. Pitie, R; Burrows, CJ; Meunier, B
      Mechanisms of DNA cleavage by copper complexes of 3-Clip-Phen and of its conjugate with a distamycin analogue

      NUCLEIC ACIDS RESEARCH
    52. Mukai, C; Kasamatsu, E; Ohyama, T; Hanaoka, M
      Studies on synthesis of optically active twelve-membered diynes: a convergent construction of a twelve-membered diketodiyne compound with C-2 symmetry

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
    53. Liu, W; Shen, B
      Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027apoprotein

      ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
    54. Boger, DL; Aquila, BM; Tse, WC; Searcey, M
      Synthesis and evaluation of a novel bleomycin A(2) analogue: continuing assessment of the linker domain

      TETRAHEDRON LETTERS
    55. Bradley, AZ; Link, AJ; Biswas, K; Kahne, D; Schwartz, J; Jones, M; Zhu, ZD; Platz, MS
      Hydrogen abstraction on photolysis of a naphthocarborane

      TETRAHEDRON LETTERS
    56. Wakayama, M; Suzuki, I; Kawakami, T; Nemoto, H; Shibuya, M
      Decarboxylative cycloaromatization of enediyne model compounds - mechanismof the radical and ionic pathway

      TETRAHEDRON LETTERS
    57. Caddick, S; Khan, S; Frost, LM; Smith, NJ; Cheung, S; Pairaudeau, G
      Studies toward the synthesis of natural and unnatural dienediynes. Part 2:A practical approach to functionalised cyclopentenones

      TETRAHEDRON
    58. Yakura, T; Tanaka, K; Kitano, T; Uenishi, J; Ikeda, M
      Stereoselective conjugate addition of alkyl groups to (S)-4-(tert-butyldimethylsilyloxy)-2-cyclopentenone derivatives

      TETRAHEDRON
    59. Alami, M; Peyrat, JF; Brion, JD
      1,2-dihalogenoalkenes: Useful linchpins to unsaturated compounds via palladium or nickel catalysis

      SYNTHESIS-STUTTGART
    60. Araki, Y; Konoike, T
      Olefin formation by deoxystannylation

      JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN
    61. Brunette, SR; Lipton, MA
      Oxyanion-accelerated C-2-C-6 cyclization of benzannulated enyne-allenes

      JOURNAL OF ORGANIC CHEMISTRY
    62. Dabdoub, MJ; Baroni, ACM
      Hydrozirconation of stannylacetylenes. Synthesis and reactions of ketene stannyl(telluro) acetals

      JOURNAL OF ORGANIC CHEMISTRY
    63. Sudhahar, GCP; Balamurugan, K; Chin, DH
      Release of the neocarzinostatin chromophore from the holoprotein does not require major conformational change of the tertiary and secondary structures induced by trifluoroethanol

      JOURNAL OF BIOLOGICAL CHEMISTRY
    64. Heyd, B; Lerat, G; Adjadj, E; Minard, P; Desmadril, M
      Reinvestigation of the proteolytic activity of neocarzinostatin

      JOURNAL OF BACTERIOLOGY
    65. Yet, L
      Metal-mediated synthesis of medium-sized rings

      CHEMICAL REVIEWS
    66. Zang, H; Gates, KS
      DNA binding and alkylation by the "left half" of azinomycin B

      BIOCHEMISTRY
    67. Jones, GB; Wright, JM; Plourde, GW; Hynd, G; Huber, RS; Mathews, JE
      A direct and stereocontrolled route to conjugated enediynes

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    68. Wenthold, PG; Lipton, MA
      A density functional molecular orbital study of the C-2-C-7 and C-2-C-6 cyclization pathways of 1,2,4-heptatrien-6-ynes. The role of benzannulation

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    69. Kraka, E; Cremer, D
      Computer design of anticancer drugs. A new enediyne warhead

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    70. Okuno, Y; Iwashita, T; Sugiura, Y
      Structural basis for reaction mechanism and drug delivery system of chromoprotein antitumor antibiotic C-1027

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    71. Oyoshi, T; Sugiyama, H
      Mechanism of DNA strand scission induced by (1,10-phenanthroline)copper complex: Major direct DNA cleavage is not through 1 ',2 '-dehydronucleotide intermediate nor beta-elimination of forming ribonolactone

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    72. Nakatani, K; Sando, S; Saito, I
      Recognition of a single guanine bulge by 2-acylamino-1,8-naphthyridine

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    73. Wender, PA; Jeon, R
      Bromoacetophenone-based photonucleases: Photoinduced cleavage of DNA by 4 '-bromoacetophenone-pyrrolecarboxamide conjugates

      ORGANIC LETTERS
    74. Nakatani, K; Okamoto, A; Saito, I
      Specific alkylation of guanine opposite to a single nucleotide bulge: A chemical probe for the bulged structure of DNA

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    75. Cabrero, J; Ben-Amor, N; Caballol, R
      Singlet-triplet gap in alpha-n-dehydrotoluene and related biradicals: An ab initio configuration interaction study

      JOURNAL OF PHYSICAL CHEMISTRY A
    76. Cook, GP; Chen, TQ; Koppisch, AT; Greenberg, MM
      The effects of secondary structure and O-2 on the formation of direct strand breaks upon UV irradiation of 5-bromodeoxyuridine-containing oligonucleotides

      CHEMISTRY & BIOLOGY
    77. Taniguchi, I; Akiyoshi, K; Sunamoto, J
      Self-aggregate nanoparticles of cholesteryl and galactoside groups-substituted pullulan and their specific binding to galactose specific lectin, RCA(120)

      MACROMOLECULAR CHEMISTRY AND PHYSICS
    78. Chakrabarti, S; Mahmood, A; Makrigiorgos, GM
      Fluorescent labelling of closely-spaced aldehydes induced in DNA by bleomycin-Fe(III)

      INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
    79. Chin, DH
      Rejection by neocarzinostatin protein through charges rather than sizes

      CHEMISTRY-A EUROPEAN JOURNAL
    80. Bruckner, R; Suffert, J
      The bis(enol triflate) route to dienediyne models of the biradical formingand DNA-cleaving natural product neocarzinostatin chromophore

      SYNLETT
    81. Takahashi, K; Hagiwara, M; Ashizawa, S; Hirama, M
      Concise synthesis of the naphthoate component of N1999-A2

      SYNLETT
    82. Hwang, JT; Tallman, KA; Greenberg, MM
      The reactivity of the 2-deoxyribonolactone lesion in single-stranded DNA and its implication in reaction mechanisms of DNA damage and repair

      NUCLEIC ACIDS RESEARCH
    83. Hughes, TS; Carpenter, BK
      Parallel mechanisms for the cycloaromatization of enyne allenes

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
    84. Zhi, YG; Teng, YW; Zhang, LF; George, J
      The synthesis of the precursor of the bicyclic enediyne - 6-sulfony-13-oxo-bicyclo[9.3.0]-tetradec-3, 8-diyne(II)

      CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
    85. Yoshida, H; Onda, M; Tajiri, T; Uchida, E; Arima, Y; Mamada, Y; Yamamoto, K; Kaneko, M; Terada, Y; Kumazaki, T
      Experience with intraarterial infusion of styrene maleic acid neocarzinostatin (SMANCS)-Lipiodol in pancreatic cancer

      HEPATO-GASTROENTEROLOGY
    86. Thorson, JS; Shen, B; Whitwam, RE; Liu, W; Li, Y; Ahlert, J
      Enediyne biosynthesis and self-resistance: A progress report

      BIOORGANIC CHEMISTRY
    87. Yoshimura, F; Kawata, S; Hirama, M
      Synthetic study of kedarcidin chromophore: atropselective construction of the ansamacrolide

      TETRAHEDRON LETTERS
    88. Wright, JM; Jones, GB
      Stereochemical control in the metallohalocarbenoid route to linear enediynes

      TETRAHEDRON LETTERS
    89. Lear, MJ; Hirama, M
      Convenient route to derivatives of the 2-deoxysugar subunits of the kedarcidin chromophore: L-mycarose and L-kedarosamine

      TETRAHEDRON LETTERS
    90. Kawai, K; Saito, I; Kawashima, E; Ishido, Y; Sugiyama, H
      Intrastrand 2 'beta hydrogen abstraction of 5 '-adjacent deoxyguanosine bydeoxyuridin-5-yl in Z-form DNA

      TETRAHEDRON LETTERS
    91. Caddick, S; Delisser, VM; Doyle, VE; Khan, S; Avent, AG; Vile, S
      Studies toward the synthesis of natural and unnatural dienediynes 1. Approaches to a functionalised bicyclic ring system

      TETRAHEDRON
    92. Kittaka, A; Kato, H; Tanaka, H; Nonaka, Y; Amano, M; Nakamura, KT; Miyasaka, T
      Face selective 6,1 '-(1-oxo)ethano bridge formation of uracil nucleosides under hypoiodite reaction conditions

      TETRAHEDRON
    93. Dopico, PG; Finn, MG
      Synthesis and cycloaromatization kinetics of aromatic allene enynes

      TETRAHEDRON
    94. Wang, KK; Zhang, HR; Petersen, JL
      Thermolysis of benzoenyne-allenes to form biradicals and subsequent intramolecular trapping with a tetraarylallene to generate two triarylmethyl radical centers

      JOURNAL OF ORGANIC CHEMISTRY
    95. Kittaka, A; Asakura, T; Kuze, T; Tanaka, H; Yamada, N; Nakamura, KT; Miyasaka, T
      Cyclization reactions of nucleoside anomeric radical with olefin tethered on base: Factors that induce anomeric stereochemistry

      JOURNAL OF ORGANIC CHEMISTRY
    96. Saalfrank, RW; Haubner, M; Deutscher, C; Bauer, W; Clark, T
      Cation-mediated, substituent-controlled, C-2-C-7 cycloaromatization of an enyne-allene

      JOURNAL OF ORGANIC CHEMISTRY
    97. Srinivasan, V; Jebaratnam, DJ; Budil, DE
      Toward enediyne mimics: Methanolysis of azoesters and a bisazoester

      JOURNAL OF ORGANIC CHEMISTRY
    98. Dai, WM; Wu, JL; Fong, KC; Lee, MYH; Lau, CW
      Regioselective synthesis of acyclic cis-enediynes via an acid-catalyzed rearrangement of 1,2-dialkynylallyl alcohols. Syntheses, computational calculations, and mechanism

      JOURNAL OF ORGANIC CHEMISTRY
    99. Casadevall, M; Fresco, PD; Kortenkamp, A
      Chromium(VI)-mediated DNA damage: oxidative pathways resulting in the formation of DNA breaks and abasic sites

      CHEMICO-BIOLOGICAL INTERACTIONS
    100. Furstner, A
      Carbon-carbon bond formations involving organochromium(III) reagents

      CHEMICAL REVIEWS


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Documento generato il 27/10/20 alle ore 17:11:14