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Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: Plasmid dependence of muscle damage and effect of poloxamer 188
MOLECULAR THERAPY
Slow accumulation of plasmid in muscle cells: Supporting evidence for a mechanism of DNA uptake by receptor-mediated endocytosis
MOLECULAR THERAPY
Epstein-Barr virus/human vector provides high-level, long-term expression of alpha(1)-antitrypsin in mice
MOLECULAR THERAPY
Intratumoral delivery of p2CMVmIL-12 using water-soluble lipopolymers
MOLECULAR THERAPY
Transfer of full-length Dmd to the diaphragm muscle of Dmd(mdx/mdx) mice through systemic administration of plasmid DNA
MOLECULAR THERAPY
Tail-vein injection of mannan-binding lectin DNA leads to high expression levels of multimeric protein in liver
MOLECULAR THERAPY
Long-term and therapeutic-level hepatic gene expression of human factor IXafter naked plasmid transfer in vivo
MOLECULAR THERAPY
Topical delivery of nucleic acids in the skin
STP PHARMA SCIENCES
Environmental adaptations as windows on molecular evolution
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Nonviral vectors in the new millennium: Delivery barriers in gene transfer
HUMAN GENE THERAPY
Sustainable systemic delivery via a single injection of lentivirus into human skin tissue
HUMAN GENE THERAPY
In vivo transfection and/or cross-priming of dendritic cells following DNAand adenoviral immunizations for immunotherapy of cancer - changes in peripheral mononuclear subsets and intracellular IL-4 and IFN-gamma lymphokine profile
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Enhanced expressions and histological characteristics of intravenously administered plasmid DNA in rat lung
JOURNAL OF KOREAN MEDICAL SCIENCE
Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1 alpha promoter
GENE THERAPY
Highly efficient gene transfer into murine liver achieved by intravenous administration of naked Epstein-Barr virus (EBV)-based plasmid vectors
GENE THERAPY
Electro transfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies
GENE THERAPY
Efficient in Vivo gene transfer by PCR amplified fragment with reduced inflammatory activity
GENE THERAPY
Electroporation microchips for in vitro gene transfection
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
Non-viral vectors in cancer gene therapy: principles and progress
ANTI-CANCER DRUGS
Long-term expression of foreign genes in normal human epidermal keratinocytes after transfection with lipid/DNA complexes
HISTOCHEMISTRY AND CELL BIOLOGY
Synergistic effect of a combined DNA and peptide vaccine against gp100 in a malignant melanoma mouse model
JOURNAL OF MOLECULAR MEDICINE-JMM
Tumor regression induced by intratumoral injection of DNA coding for humaninterleukin 12 into melanoma metastases in gray horses
JOURNAL OF MOLECULAR MEDICINE-JMM
Development of gene drug delivery systems based on pharmacokinetic studies
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Electroporation microchips for continuous gene transfection
SENSORS AND ACTUATORS B-CHEMICAL
Transfection of normal human epidermal keratinocytes with lipid/DNA complexes in vitro
JOURNAL OF LIPOSOME RESEARCH
Ultrasound gene therapy: On the road from concept to reality
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
Long-term tumor growth suppression in mice immunized with naked DNA of thehuman tumor antigen mucin (MUC1)
CANCER IMMUNOLOGY IMMUNOTHERAPY
Growth factors for therapeutic angiogenesis in cardiovascular diseases
REVISTA ESPANOLA DE CARDIOLOGIA
DNA vaccination with asparaginyl endopeptidase (Sm32) from the parasite Schistosoma mansoni: anti-fecundity effect induced in mice
VACCINE
Topical application of HIV DNA vaccine with cytokine-expression plasmids induces strong antigen-specific immune responses
VACCINE
Immunization of livestock with DNA vaccines: current studies and future prospects
VACCINE
Type I interferons and herpes simplex virus infection - A naked DNA approach as a therapeutic option?
IMMUNOLOGIC RESEARCH
The feasibility and safety of fluoroscopy-guided percutaneous intramyocardial gene injection in porcine heart
INTERNATIONAL JOURNAL OF CARDIOLOGY
Somatic gene therapy in the cardiovascular system
ANNUAL REVIEW OF PHYSIOLOGY
DNA vaccination with the Hantaan virus M gene protects hamsters against three of four HFRS hantaviruses and elicits a high-titer neutralizing antibody response in rhesus monkeys
JOURNAL OF VIROLOGY
Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo
JOURNAL OF VIROLOGY
Therapeutic angiogenesis for ischemic cardiovascular disease
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Assessment of risks associated with cardiovascular gene therapy in human subjects
CIRCULATION RESEARCH
Rabbit EPO gene and cDNA: Expression of rabbit EPO after intramuscular injection of pDNA
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Direct in vivo transfer of plasmid DNA into murine tumors: Effects of endotoxin presence and transgene localization
ACTA BIOCHIMICA POLONICA
Gene therapy for peripheral vascular disease
ISRAEL MEDICAL ASSOCIATION JOURNAL
Adeno-associated virus expresses transgenes in hair follicles and epidermis
MOLECULAR THERAPY
Gene therapy of autoimmune diseases with vectors encoding regulatory cytokines or inflammatory cytokine inhibitors
JOURNAL OF GENE MEDICINE
Gene therapy in wound repair and regeneration
WOUND REPAIR AND REGENERATION
Genetic immunization for the recovery and purification of recombinant proteins
PROTEIN EXPRESSION AND PURIFICATION
Nonviral skin gene therapy
HUMAN GENE THERAPY
Genetic correction of inherited epidermal disorders
HUMAN GENE THERAPY
T cell receptor mimic peptides and their potential application in T-cell-mediated disease
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by intramuscular injection of plasmid DNA
GENE THERAPY
Long-term expression of human alpha 1-antitrypsin gene in mouse liver achieved by intravenous administration of plasmid DNA using a hydrodynamics-based procedure
GENE THERAPY
Sodium phosphate enhances plasmid DNA expression in vivo
GENE THERAPY
Therapeutic application of T cell receptor mimic peptides or cDNA in the treatment of T cell-mediated skin diseases
GENE THERAPY
A combination of poloxamers increases gene expression of plasmid DNA in skeletal muscle
GENE THERAPY
Gene expression after intrarenal injection of plasmid DNA in the rat
PEDIATRIC NEPHROLOGY
Expression of Escherichia coli B nitroreductase in established human tumorxenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954
CANCER GENE THERAPY
Naked DNA and adenoviral immunizations for immunotherapy of prostate cancer: A phase I/II clinical trial
EUROPEAN UROLOGY
DNA vaccines: Development, standardization and regulation
INTERVIROLOGY
Immune response against Mycobacterium tuberculosis: implications for vaccine development
JOURNAL OF BIOTECHNOLOGY
Responses of chickens to a recombinant refractile body antigen of Eimeria tenella administered using various immunizing strategies
POULTRY SCIENCE
Gene gun-mediated DNA immunization primes development of mucosal immunity against bovine herpesvirus 1 in cattle
JOURNAL OF VIROLOGY
Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice
JOURNAL OF IMMUNOLOGY
In vitro and in vivo transfection of p21 gene enhances cyclosporin A-mediated inhibition of lymphocyte proliferation
JOURNAL OF IMMUNOLOGY
Cell-mediated DNA transport between distant inflammatory sites following intradermal DNA immunization in the presence of adjuvant
JOURNAL OF IMMUNOLOGY
Single-shot plasmid DNA intrasplenic immunization for the production of monoclonal antibodies - Persistent expression of DNA
JOURNAL OF IMMUNOLOGICAL METHODS
Improved expression of vascular endothelial growth factor by naked DNA in mouse skeletal muscles: Implication for gene therapy of ischemic diseases
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
In vivo gene transfer method in keratinocyte gene therapy: Intradermal injection of DNA complexed with high mobility group-1 protein in rats
ACTA DERMATO-VENEREOLOGICA
Direct transfer of IL-12 gene into growing Renca tumors
ACTA BIOCHIMICA POLONICA
Antisense RNA gene therapy for studying and modulating biological processes
CELLULAR AND MOLECULAR LIFE SCIENCES
DNA vaccination against parasites: hope or mirage?
ACTA PARASITOLOGICA
Epicutaneous and transcutaneous immunization using DNA or proteins
EUROPEAN JOURNAL OF DERMATOLOGY
Intramuscular administration of expression plasmids encoding interferon-gamma receptor/IgG1 or IL-4/IgG1 chimeric proteins protects from autoimmunity
JOURNAL OF GENE MEDICINE
A direct in vivo approach for skin gene therapy
PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS
Targeting the skin for genetic immunization
PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS
Entry sites for oral vaccines and drugs: A role for M cells, enterocytes and dendritic cells?
SEMINARS IN IMMUNOLOGY
Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein
GENE THERAPY
In vivo gene introduction into keratinocytes using jet injection
GENE THERAPY
Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice
GENE THERAPY
Uptake of exogenous DNA via the skin
JOURNAL OF MOLECULAR MEDICINE-JMM
Intradermal transfer of caspase-1 (CASP1) DNA into mouse dissects: role ofCASP1 in interleukin-1 beta associated skin inflammation and apoptotic cell death
JOURNAL OF DERMATOLOGICAL SCIENCE
Reduced melanoma tumor formation in mice immunized with DNA expressing themelanoma-specific antigen gp100/pmel17
LEUKEMIA
In vivo introduction of the interleukin-6 gene into keratinocytes
MOLECULAR MEDICINE: NOVEL FINDINGS OF GENE DIAGNOSIS, REGULATION OF GENE EXPRESSION, AND GENE THERAPY
In vivo introduction of cytokine genes into keratinocytes for approaching to cytokine gene therapy
MOLECULAR MEDICINE: NOVEL FINDINGS OF GENE DIAGNOSIS, REGULATION OF GENE EXPRESSION, AND GENE THERAPY
Vaccine delivery to animals
ADVANCED DRUG DELIVERY REVIEWS
Immunization strategies in advanced melanoma
BIOGENIC AMINES
Immunological properties of gene vaccines delivered by different routes
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
High-efficiency gene transfer into skeletal muscle mediated by electric pulses
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Dendritic cell (DC)-based anti-infective strategies: DCs engineered to secrete IL-12 are a potent vaccine in a murine model of an intracellular infection
JOURNAL OF IMMUNOLOGY
Nucleic acid immunization: concepts and techniques associated with third generation vaccines
JOURNAL OF IMMUNOLOGICAL METHODS
Demonstration of the pathogenic effect of point mutated keratin 9 in vivo
FEBS LETTERS
Successful autotransplantation of microvessel fragments into the rat heart
EUROPEAN SURGICAL RESEARCH
Efficient gene transfer into Xiphophorus muscle and melanoma by injection of supercoiled plasmid DNA
MOLECULAR MARINE BIOLOGY AND BIOTECHNOLOGY
GENETIC IMMUNIZATION WITH GLYCOPROTEIN-63 CDNA RESULTS IN A HELPER T-CELL TYPE-1 IMMUNE-RESPONSE AND PROTECTION IN A MURINE MODEL OF LEISHMANIASIS
Human gene therapy
SUPERIORITY OF THE EAR PINNA OVER MUSCLE-TISSUE AS SITE FOR DNA VACCINATION
Gene therapy
ENHANCED GENE-EXPRESSION IN MOUSE LUNG BY PROLONGING THE RETENTION TIME OF INTRAVENOUSLY INJECTED PLASMID DNA
Gene therapy
Development of a multigenic plasmid vector for HCV DNA immunization
RESEARCH IN VIROLOGY
INTRADERMAL DNA IMMUNIZATION OF MICE AGAINST INFLUENZA-A VIRUS USING THE NOVEL POWDERJECT(R) SYSTEM
Vaccine
QUANTITATIVE-ANALYSIS OF THE IMMUNOPOTENCY OF GENETICALLY TRANSFECTEDDENDRITIC CELLS
Proceedings of the National Academy of Sciences of the United Statesof America
IMMUNIZATION OF PIGS WITH A PARTICLE-MEDIATED DNA VACCINE TO INFLUENZA-A VIRUS PROTECTS AGAINST CHALLENGE WITH HOMOLOGOUS VIRUS
Journal of virology
ACTIVATION OF CUTANEOUS DENDRITIC CELLS BY CPG-CONTAINING OLIGODEOXYNUCLEOTIDES - A ROLE FOR DENDRITIC CELLS IN THE AUGMENTATION OF TH1 RESPONSES BY IMMUNOSTIMULATORY DNA
The Journal of immunology (1950)
INDUCTION OF KERATINOCYTE PROLIFERATION AND LYMPHOCYTIC INFILTRATION BY IN-VIVO INTRODUCTION OF THE IL-6 GENE INTO KERATINOCYTES AND POSSIBILITY OF KERATINOCYTE GENE-THERAPY FOR INFLAMMATORY SKIN DISEASES USING IL-6 MUTANT-GENES
The Journal of immunology (1950)