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    1. Gerber, JG; Rosenkranz, S; Segal, Y; Aberg, J; D'Amico, R; Mildvan, D; Gulick, R; Hughes, V; Flexner, C; Aweeka, F; Hsu, A; Gal, J
      Effect of ritonavir/saquinavir on stereoselective pharmacokinetics of methadone: Results of AIDS clinical trials group (ACTG) 401

      JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
    2. Kulkarni, AP
      Role of biotransformation in conceptal toxicity of drugs and other chemicals

      CURRENT PHARMACEUTICAL DESIGN
    3. Lucas, ACS; Bermejo, AM; Tabernero, MJ; Fernandez, P; Campora, P
      Influence of concomitant drugs on methadone elimination half-life in patients under a maintenance treatment

      ADDICTION BIOLOGY
    4. Moolchan, ET; Umbricht, A; Epstein, D
      Therapeutic drug monitoring in methadone maintenance: Choosing a matrix

      JOURNAL OF ADDICTIVE DISEASES
    5. Zhang, TY; Oyama, T; Aoshima, A; Hidaka, H; Zhao, JC; Serpone, N
      Photooxidative N-demethylation of methylene blue in aqueous TiO2 dispersions under UV irradiation

      JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
    6. Lang, T; Klein, K; Fischer, J; Nussler, AK; Neuhaus, P; Hofmann, U; Eichelbaum, M; Schwab, M; Zanger, UM
      Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

      PHARMACOGENETICS
    7. Gervasini, G; Martinez, C; Agundez, JAG; Garcia-Gamito, FJ; Benitez, J
      Inhibition of cytochrome P4502C9 activity in vitro by 5-hydroxytryptamine and adrenaline

      PHARMACOGENETICS
    8. Hiep, BT; Fernandez, C; Tod, M; Banide, H; Thuillier, A; Lacour, B; Farinotti, R; Gimenez, F
      Intestinal absorption and metabolism of chlorpheniramine enantiomers in rat

      CHIRALITY
    9. Guengerich, FP
      Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

      CHEMICAL RESEARCH IN TOXICOLOGY
    10. Boulton, DW; Arnaud, P; DeVane, CL
      A single dose of methadone inhibits cytochrome P-4503A activity in healthyvolunteers as assessed by the urinary cortisol ratio

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    11. Oda, Y; Hamaoka, N; Hiroi, T; Imaoka, S; Hase, I; Tanaka, K; Funae, Y; Ishizaki, T; Asada, A
      Involvement of human liver cytochrome P4502B6 in the metabolism of propofol

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    12. Yokono, A; Morita, S; Someya, T; Hirokane, G; Okawa, M; Shimoda, K
      The effect of CYP2C19 and CYP2D6 genotypes on the metabolism of clomipramine in Japanese psychiatric patients

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    13. Eap, CB; Bondolfi, G; Zullino, D; Savary-Cosendai, L; Powell-Golay, K; Kosel, M; Baumann, P
      Concentrations of the enantiomers of fluoxetine and norfluoxetine after multiple doses of fluoxetine in cytochrome P4502D6 poor and extensive metabolizers

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    14. Eap, CB; Broly, F; Mino, A; Hammig, R; Deglon, JJ; Uehlinger, C; Meili, D; Chevalley, AF; Bertschy, G; Zullino, D; Kosel, M; Preisig, M; Baumann, P
      Cytochrome P450 2D6 genotype and methadone steady-state concentrations

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    15. Bart, PA; Rizzardi, PG; Gallant, S; Golay, KP; Baumann, P; Pantaleo, G; Eap, CB
      Methadone blood concentrations are decreased by the administration of abacavir plus amprenavir

      THERAPEUTIC DRUG MONITORING
    16. Charlier, C; Dessalles, MC; Plomteux, G
      Methadone maintenance treatment: Is it possible to adapt the daily doses to the metabolic activity of the patient?

      THERAPEUTIC DRUG MONITORING
    17. Al-Alaiyan, S; Al-Rawithi, S; Raines, D; Yusuf, A; Legayada, E; Shoukri, MM; El-Yazigi, A
      Caffeine metabolism in premature infants

      JOURNAL OF CLINICAL PHARMACOLOGY
    18. Venkatakrishnan, K; von Moltke, LL; Greenblatt, DJ
      Human drug metabolism and the cytochromes P450: Application and relevance of in vitro models

      JOURNAL OF CLINICAL PHARMACOLOGY
    19. Venkatakrishnan, K; Schmider, J; Harmatz, JS; Ehrenberg, BL; von Moltke, LL; Graf, JA; Mertzanis, P; Corbett, KE; Rodriguez, MC; Shader, RI; Greenblatt, DJ
      Relative contribution of CYP3A to amitriptyline clearance in humans: In vitro and in vivo studies

      JOURNAL OF CLINICAL PHARMACOLOGY
    20. Von Moltke, LL; Greenblatt, DJ; Giancarlo, GM; Granda, BW; Harmatz, JS; Shader, RI
      Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram

      DRUG METABOLISM AND DISPOSITION
    21. Stormer, E; Perloff, MD; Von Moltke, LL; Greenblatt, DJ
      Methadone inhibits rhodamine123 transport in Caco-2 cells

      DRUG METABOLISM AND DISPOSITION
    22. Yu, AM; Haining, RL
      Comparative contribution to dextromethorphan metabolism by cytochrome P450isoforms in vitro: Can dextromethorphan be used as a dual probe for both CYP2D6 and CYP3A activities?

      DRUG METABOLISM AND DISPOSITION
    23. Kosuge, K; Jun, Y; Watanabe, H; Kimura, M; Nishimoto, M; Ishizaki, T; Ohashi, K
      Effects of CYP3A4 inhibition by diltiazem on pharmacokinetics and dynamicsof diazepam in relation to CYP2C19 genotype status

      DRUG METABOLISM AND DISPOSITION
    24. Kobayashi, K; Kogo, M; Tani, M; Shimada, N; Ishizaki, T; Numazawa, S; Yoshida, T; Yamamoto, T; Kuroiwa, Y; Chiba, K
      Role of CYP2C19 in stereoselective hydroxylation of mephobarbital by humanliver microsomes

      DRUG METABOLISM AND DISPOSITION
    25. Fraile, LJ; Bregante, MA; Garcia, MA; Solans, C
      Altered diltiazem metabolism in the neonatal rabbit following intra-uterine chronic exposure to diltiazem

      XENOBIOTICA
    26. Fujimaki, Y; Arai, N; Nakazawa, T; Fujimaki, M
      Nefiracetam metabolism by human liver microsomes: role of cytochrome P450 3A4 and cytochrome P450 1A2 in 5-hydroxynefiracetam formation

      JOURNAL OF PHARMACY AND PHARMACOLOGY
    27. Oda, Y; Kharasch, ED
      Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): Potential contribution of intestinal metabolism to presysternic clearance and bioactivation

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    28. Ring, BJ; Eckstein, JA; Gillespie, JS; Binkley, SN; Vandenbranden, M; Wrighton, SA
      Identification of the human cytochromes P450 responsible for in vitro formation of R- and S-norfluoxetine

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    29. Venkatakrishnan, K; Von Moltke, LL; Greenblatt, DJ
      Application of the relative activity factor approach in scaling from heterologously expressed cytochromes P450 to human liver microsomes: Studies on amitriptyline as a model substrate

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    30. Oda, Y; Kharasch, ED
      Metabolism of levo-alpha-acetylmethadol (LAAM) by human liver cytochrome P450: Involvement of CYP3A4 characterized by atypical kinetics with two binding sites

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    31. Klein, PD
      C-13 breath tests: Visions and realities

      JOURNAL OF NUTRITION
    32. Wang, JH; Liu, ZQ; Wang, W; Chen, XP; Shu, Y; He, N; Zhou, HH
      Pharmacokinetics of sertraline in relation to genetic polymorphism of CYP2C19

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    33. Boulton, DW; Arnaud, P; DeVane, CL
      Pharmacokinetics and pharmacodynamics of methadone enantiomers after a single oral dose of racemate

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    34. Bottiger, Y; Sawe, J; Brattstrom, C; Tollemar, J; Burke, JT; Hass, G; Zimmerman, JJ
      Pharmacokinetic interaction between single oral doses of ditiazem and sirolimus in healthy volunteers

      CLINICAL PHARMACOLOGY & THERAPEUTICS
    35. Ariyoshi, N; Miyazaki, M; Toide, K; Sawamura, Y; Kamataki, T
      A single nucleotide polymorphism of CYP2B6 found in Japanese enhances catalytic activity by autoactivation

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    36. Ezzat, AR; el-Din, SHS; Ebeid, FA
      Effect of praziquantel treatment on the activities of some liver microsomal enzymes in mice infected with Schistosoma mansoni

      ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
    37. Court, MH; Duan, SX; Hesse, LM; Venkatakrishnan, K; Greenblatt, DJ
      Cytochrome P-4502B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes

      ANESTHESIOLOGY
    38. Kirchheiner, J; Brosen, K; Dahl, ML; Gram, LF; Kasper, S; Roots, I; Sjoqvist, F; Spina, E; Brockmoller, J
      CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages

      ACTA PSYCHIATRICA SCANDINAVICA
    39. Iley, J; Tolando, R
      The oxidative dealkylation of tertiary amides: mechanistic aspects

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
    40. Foster, DJR; Somogyi, AA; Bochner, F
      Stereoselective quantification of methadone and its major oxidative metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, in human urine using high-performance liquid chromatography

      JOURNAL OF CHROMATOGRAPHY B
    41. Ereshefsky, L; Dugan, D
      Review of the pharmacokinetics, pharmacogenetics, and drug interaction potential of antidepressants: Focus on venlafaxine

      DEPRESSION AND ANXIETY
    42. Fukuzumi, S
      Electron transfer chemistry of metalloporphyrins and related metal complexes

      JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
    43. Ozeryanskii, VA; Pozharskii, AF; Vistorobskii, NV
      peri-naphthylenediamines. 28. Nitration of 1,8-bis(dimethylamino)naphthalene and 5,6-bis(dimethylamino)acenaphthene in neutral and weakly acidic media. The first case of isolation of o-nitro and o,o '-dinitro derivatives of "proton sponges"

      RUSSIAN CHEMICAL BULLETIN
    44. Haritos, VS; Ghabrial, H; Ahokas, JT; Ching, MS
      Role of cytochrome P450 2D6 (CYP2D6) in the stereospecific metabolism of E- and Z-doxepin

      PHARMACOGENETICS
    45. Paine, MF; Davis, CL; Shen, DD; Marsh, CL; Raisys, VA; Thummel, KE
      Can oral midazolam predict oral cyclosporine disposition?

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    46. Niwa, T; Tsutsui, M; Kishimoto, K; Yabusaki, Y; Ishibashi, F; Katagiri, M
      Inhibition of drug-metabolizing enzyme activity in human hepatic cytochrome P450s by bisphenol A

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    47. Feyk, LA; Giesy, JP; Bosveld, ATC; van den Berg, M
      Changes in cytochrome P4501A activity during development in common tern chicks fed polychlorinated biphenyls, as measured by the caffeine breath test

      ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
    48. Eap, CB; Bourquin, M; Martin, JL; Spagnoli, J; Livoti, S; Powell, K; Baumann, P; Deglon, JJ
      Plasma concentrations of the enantiomers of methadone and therapeutic response in methadone maintenance treatment

      DRUG AND ALCOHOL DEPENDENCE
    49. Wilcox, RA; Owen, H
      Variable cytochrome P450 2D6 expression and metabolism of codeine and other opioid prodrugs: Implications for the Australian anaesthetist

      ANAESTHESIA AND INTENSIVE CARE
    50. Ong, CE; Coulter, S; Birkett, DJ; Bhasker, CR; Miners, JO
      The xenobiotic inhibitor profile of cytochrome P4502C8

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    51. Foster, DJR; Somogyi, AA; Dyer, KR; White, JM; Bochner, F
      Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    52. McLure, JA; Miners, JO; Birkett, DJ
      Nonspecific binding of drugs to human liver microsomes

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    53. Hover, CG; Kulkarni, AP
      Hydroperoxide specificity of plant and human tissue lipoxygenase: an in vitro evaluation using N-demethylation of phenothiazines

      BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
    54. Geletko, SM; Erickson, AD
      Decreased methadone effect after ritonavir initiation

      PHARMACOTHERAPY
    55. Ferreira, VS; Magalhaes, DB; Kling, SH; da Silva, JG; Bon, EPS
      N-demethylation of methylene blue by lignin peroxidase from Phanerochaete chrysosporium - Stoichiometric relation for H2O2 consumption

      APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
    56. Fehr, C; Grunder, G; Hiemke, C; Dahmen, N
      Increase in serum clomipramine concentrations caused by valproate

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    57. Olesen, OV; Linnet, K
      Fluvoxamine-clozapine drug interaction: Inhibition in vitro of five cytochrome P450 isoforms involved in clozapine metabolism

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
    58. Shu, Y; Zhou, HH
      Individual and ethnic differences in CYP2C19 activity in Chinese populations

      ACTA PHARMACOLOGICA SINICA
    59. Liu, ZQ; Cheng, ZN; Wang, W; Tan, ZR; Ou-Yang, DS; Zhou, HH
      Determination of fluoxetine and its metabolite norfluoxetine in human liver microsomes by reversed-phase HPLC in vitro

      ACTA PHARMACOLOGICA SINICA
    60. Wieling, J; Tamminga, WJ; Sakiman, EP; Oosterhuis, B; Wemer, J; Jonkman, JHG
      Evaluation of analytical and clinical performance of a dual-probe phenotyping method for CYP2D6 polymorphism and CYP3A4 activity screening

      THERAPEUTIC DRUG MONITORING
    61. Haffen, E; Paintaud, G; Berard, M; Masuyer, C; Bechtel, Y; Bechtel, PR
      On the assessment of drug metabolism by assays of codeine and its main metabolites

      THERAPEUTIC DRUG MONITORING
    62. Zheng, ZC; Jamour, M; Klotz, U
      Stereoselective HPLC-assay for citalopram and its metabolites

      THERAPEUTIC DRUG MONITORING
    63. Khan, A; Shad, MU; Preskorn, SH
      Lack of sertraline efficacy probably due to an interaction with carbamazepine

      JOURNAL OF CLINICAL PSYCHIATRY
    64. Houston, JB; Kenworthy, KE
      In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model

      DRUG METABOLISM AND DISPOSITION
    65. Molden, E; Christensen, H; Sund, RB
      Extensive metabolism of diltiazem and P-glycoprotein-mediated efflux of desacetyl-diltiazem (M1) by rat jejunum in vitro

      DRUG METABOLISM AND DISPOSITION
    66. Venkatakrishnan, K; Von Moltke, LL; Court, MH; Harmatz, JS; Crespi, CL; Greenblatt, DJ
      Comparison between cytochrome P450 (CYP) content and relative activity approaches to scaling from cDNA-expressed CYPs to human liver microsomes: Ratios of accessory proteins as sources of discrepancies between the approaches

      DRUG METABOLISM AND DISPOSITION
    67. McGinnity, DF; Parker, AJ; Soars, M; Riley, RJ
      Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s

      DRUG METABOLISM AND DISPOSITION
    68. Stormer, E; Von Moltke, LL; Shader, RI; Greenblatt, DJ
      Metabolism of the antidepressant mirtazapine in vitro: Contribution of cytochromes P-450 1A2, 2D6, and 3A4

      DRUG METABOLISM AND DISPOSITION
    69. Hesse, LM; Venkatakrishnan, K; Court, MH; Von Moltke, LL; Duan, SX; Shader, RI; Greenblatt, DJ
      CYP2B6 mediates the in vitro hydroxylation of bupropion: Potential drug interactions with other antidepressants

      DRUG METABOLISM AND DISPOSITION
    70. Faucette, SR; Hawke, RL; Lecluyse, EL; Shord, SS; Yan, BF; Laethem, RM; Lindley, CM
      Validation of bupropion hydroxylation as a selective marker of human cytochrome P4502B6 catalytic activity

      DRUG METABOLISM AND DISPOSITION
    71. Renwick, AB; Surry, D; Price, RJ; Lake, BG; Evans, DC
      Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms

      XENOBIOTICA
    72. Scharf, ME; Siegfried, BD; Meinke, LJ; Wright, RJ; Chandler, LD
      Cytochrome P450-mediated N-demethylation activity and induction in insecticide-resistant and susceptible western corn rootworm populations (Coleoptera : Chrysomelidae)

      PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
    73. Chladek, J; Zimova, G; Beranek, M; Martinkova, J
      In-vivo indices of CYP2D6 activity: comparison of dextromethorphan metabolic ratios in 4-h urine and 3-h plasma

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    74. Fukuda, T; Nishida, Y; Zhou, Q; Yamamoto, I; Kondo, S; Azuma, J
      The impact of the CYP2D6 and CYP2C19 genotypes on venlafaxine pharmacokinetics in a Japanese population

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    75. Fleischhacker, W; Richter, B
      Novel ring systems in morphinoides II: C8,17-ethano-bridged 4,5-epoxyhasubanans

      MONATSHEFTE FUR CHEMIE
    76. Ladona, MG; Gonzalez, ML; Rane, A; Peter, RM; de la Torre, R
      Cocaine metabolism in human fetal and adult liver microsomes is related tocytochrome P450 3A expression

      LIFE SCIENCES
    77. Stormer, ES; von Moltke, LL; Greenblatt, DJ
      Scaling drug biotransformation data from cDNA-expressed cytochrome P-450 to human liver: A comparison of relative activity factors and human liver abundance in studies of mirtazapine metabolism

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    78. Shu, Y; Wang, LS; Xu, ZH; He, N; Xiao, WM; Wang, W; Huang, SL; Zhou, HH
      5-hydroxylation of omeprazole by human liver microsomal fractions from Chinese populations related to CYP2C19 gene dose and individual ethnicity

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    79. Venkatakrishnan, K; von Moltke, LL; Obach, RS; Greenblatt, DJ
      Microsomal binding of amitriptyline: Effect on estimation of enzyme kinetic parameters in vitro

      JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
    80. Van Haandel, MJH; Saraber, FCE; Boersma, MG; Laane, C; Fleming, Y; Weenen, H; Rietjens, IMCM
      Characterization of different commercial soybean peroxidase preparations and use of the enzyme for N-demethylation of methyl N-methylanthranilate to produce the food flavor methylanthranilate

      JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
    81. Hover, CG; Kulkarni, AP
      Lipoxygenase-mediated hydrogen peroxide-dependent N-demethylation of N,N-dimethylaniline and related compounds

      CHEMICO-BIOLOGICAL INTERACTIONS
    82. Voirol, P; Jonzier-Perey, M; Porchet, F; Reymond, MJ; Janzer, RC; Bouras, C; Strobel, HW; Kosel, M; Eap, CB; Baumann, P
      Cytochrome P-450 activities in human and rat brain microsomes

      BRAIN RESEARCH
    83. Zalma, A; von Moltke, LL; Granda, BW; Harmatz, JS; Shader, RI; Greenblatt, DJ
      In vitro metabolism of trazodone by CYP3A: Inhibition by ketoconazole and human immunodeficiency viral protease inhibitors

      BIOLOGICAL PSYCHIATRY
    84. Hosea, NA; Miller, GP; Guengerich, FP
      Elucidation of distinct ligand binding sites for cytochrome P450 3A4

      BIOCHEMISTRY
    85. Cho, AK; Narimatsu, S; Kumagai, Y
      Metabolism of drugs of abuse by cytochromes P450

      ADDICTION BIOLOGY
    86. Reid, JM; Kuffel, MJ; Miller, JK; Rios, R; Ames, MM
      Metabolic activation of dacarbazine by human cytochromes P450: The role ofCYP1A1, CYP1A2, and CYP2E1

      CLINICAL CANCER RESEARCH
    87. Rostami-Hodjegan, A; Kroemer, HK; Tucker, GT
      In-vivo indices of enzyme activity: the effect of renal impairment on the assessment of CYP2D6 activity

      PHARMACOGENETICS
    88. Lucas, D; Ferrara, R; Gonzalez, E; Bodenez, P; Albores, A; Manno, M; Berthou, F
      Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans

      PHARMACOGENETICS
    89. Daniel, WA; Syrek, M; Wojcikowski, J
      The influence of selective serotonin reuptake inhibitors on the plasma andbrain pharmacokinetics of the simplest phenothiazine neuroleptic promazinein the rat

      EUROPEAN NEUROPSYCHOPHARMACOLOGY
    90. Wang, JS; Backman, JT; Wen, X; Taavitsainen, P; Neuvonen, PJ; Kivisto, KT
      Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro

      PHARMACOLOGY & TOXICOLOGY
    91. Bouer, R; Barthe, L; Philibert, C; Tournaire, C; Woodley, J; Houin, G
      The roles of P-glycoprotein and intracellullar metabolism in the intestinal absorption of methadone: in vitro studies using the rat everted intestinal sac

      FUNDAMENTAL & CLINICAL PHARMACOLOGY
    92. Chladek, J; Zimova, G; Martinkova, J; Tuma, I
      Intra-individual variability and influence of urine collection period on dextromethorphan metabolic ratios in healthy subjects

      FUNDAMENTAL & CLINICAL PHARMACOLOGY
    93. Ekins, S; Wrighton, SA
      The role of CYP2B6 in human xenobiotic metabolism

      DRUG METABOLISM REVIEWS
    94. Schmider, J; Von Moltke, LL; Shader, RI; Harmatz, JS; Greenblatt, DJ
      Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: Evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine

      DRUG METABOLISM REVIEWS
    95. Kenworthy, KE; Bloomer, JC; Clarke, SE; Houston, JB
      CYP3A4 drug interactions: correlation of 10 in vitro probe substrates

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    96. Rostami-Hodjegan, A; Wolff, K; Hay, AWM; Raistrick, D; Calvert, R; Tucker, GT
      Population pharmacokinetics of methadone in opiate users: characterizationof time-dependent changes

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    97. Foster, DJR; Somogyi, AA; Bochner, F
      Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    98. Tan, JY; Levin, GM
      Citalopram in the treatment of depression and other potential uses in psychiatry

      PHARMACOTHERAPY
    99. Min, DI; Ku, YM; Vichiendilokkul, A; Fleckenstein, LL
      A urine metabolic ratio of dextromethorphan and 3-methoxymorphinan as a probe for CYP3A activity and prediction of cyclosporine clearance in healthy volunteers

      PHARMACOTHERAPY
    100. Greenblatt, DJ; Von Moltke, LL; Harmatz, JS; Shader, RI
      Human cytochromes and some newer antidepressants: Kinetics, metabolism, and drug interactions

      JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY


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Documento generato il 28/02/20 alle ore 22:51:52