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La ricerca find articoli where soggetti phrase all words 'N-DEALKYLATION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 68 riferimenti
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    1. Zablotowicz, RM; Locke, MA; Hoagland, RE; Knight, SS; Cash, B
      Fluorescent Pseudomonas isolates from Mississippi Delta oxbow lakes: In vitro herbicide biotransformations

      ENVIRONMENTAL TOXICOLOGY
    2. Iley, J; Tolando, R; Constantino, L
      Chemical and microsomal oxidation of tertiary amides: regio- and stereoselective aspects

      JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
    3. Kuttab, S; Shang, J; Castagnoli, N
      Rat liver microsomal enzyme catalyzed oxidation of 4-phenyl-trans-1-(2-phenylcyclopropyl)-1,2,3,6-tetrahydropyridine

      BIOORGANIC & MEDICINAL CHEMISTRY
    4. Ramamoorthy, Y; Tyndale, RF; Sellers, EM
      Cytochrome P450 2D6.1 and cytochrome P450 2D6.10 differ in catalytic activity for multiple substrates

      PHARMACOGENETICS
    5. Gan, JP; Skipper, PL; Tannenbaum, SR
      Oxidation of 2,6-dimethylaniline by recombinant human cytochrome P450s andhuman liver microsomes

      CHEMICAL RESEARCH IN TOXICOLOGY
    6. Shin, JG; Kane, K; Flockhart, DA
      Potent inhibition of CYP2D6 by haloperidol metabolites: stereoselective inhibition by reduced haloperidol

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    7. Hayhurst, GP; Harlow, J; Chowdry, J; Gross, E; Hilton, E; Lennard, MS; Tucker, GT; Ellis, SW
      Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6

      BIOCHEMICAL JOURNAL
    8. Fang, J; Mckay, G; Song, JX; Remillrd, A; Li, XM; Midha, K
      In vitro characterization of the metabolism of haloperidol using recombinant cytochrome P450 enzymes and human liver microsomes

      DRUG METABOLISM AND DISPOSITION
    9. Vickers, AEM; Zollinger, M; Dannecker, R; Tynes, R; Heitz, F; Fischer, V
      In vitro metabolism of tegaserod in human liver and intestine: Assessment of drug interactions

      DRUG METABOLISM AND DISPOSITION
    10. Lohmann, AB; Smith, FL
      Buprenorphine substitution ameliorates spontaneous withdrawal in fentanyl-dependent rat pups

      PEDIATRIC RESEARCH
    11. Miller, GP; Hanna, IH; Nishimura, Y; Guengerich, FP
      Oxidation of phenethylamine derivatives by cytochrome P450 2D6: The issue of substrate protonation in binding and catalysis

      BIOCHEMISTRY
    12. Caproiu, M; Florea, C; Galli, C; Petride, A; Petride, H
      Oxidation of N-benzyl aziridine by molecular iodine: Competition of electron transfer and heterolytic pathways

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    13. Hata, M; Hoshino, T; Tsuda, M
      An ultimate species in the substrate oxidation process by cytochrome P-450

      CHEMICAL COMMUNICATIONS
    14. Miyazaki, M; Maekawa, C; Iwanaga, K; Morimoto, K; Kakemi, M
      Bioavailability assessment of disopyramide using pharmacokinetic-pharmacodynamic (PK-PD) modeling in the rat

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    15. Olesen, OV; Linnet, K
      Identification of the human cytochrome P450 isoforms mediating in vitro N-dealkylation of perphenazine

      BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
    16. Feng, J; Shi, J; Sirimanne, SR; Mounier-Lee, CE; May, SW
      Kinetic and stereochemical studies on novel inactivators of C-terminal amidation

      BIOCHEMICAL JOURNAL
    17. Valoti, M; Fusi, F; Frosini, M; Pessina, F; Tipton, KF; Sgaragli, GP
      Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl

      EUROPEAN JOURNAL OF PHARMACOLOGY
    18. Boersma, MG; Primus, JL; Koerts, J; Veeger, C; Rietjens, IMCM
      Heme-(hydro)peroxide mediated O- and N-dealkylation - A study with microperoxidase

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    19. Yun, CH; Miller, GP; Guengerich, FP
      Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants

      BIOCHEMISTRY
    20. Sato, H; Guengerich, FP
      Oxidation of 1,2,4,5-tetramethoxybenzene to a cation radical by cytochromeP450

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    21. Lockwood, MA; Blubaugh, TJ; Collier, AM; Lovell, S; Mayer, JM
      Oxidations of C-H and O-H bonds by isolated copper(III) complexes

      ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
    22. Cuppoletti, A; Dagostin, C; Florea, C; Galli, C; Gentili, P; Lanzalunga, O; Petride, A; Petride, H
      The oxidation of N-benzylaziridine catalyzed by iron porphyrin: Radical versus electron transfer mechanism

      CHEMISTRY-A EUROPEAN JOURNAL
    23. Klinger, W; Oelschlager, H; Rothley, D; Karge, E; Seeling, A
      Interaction of chlormezanone enantiomers with rat liver microsomes

      EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
    24. Pan, L; Belpaire, FM
      In vitro study on the involvement of CYP1A2, CYP2D6 and CYP3A4 in the metabolism of haloperidol and reduced haloperidol

      EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
    25. Spiegelstein, O; Yagen, B; Bialer, M
      Structure-pharmacokinetic-pharmacodynamic relationships of N-alkyl derivatives of the new antiepileptic drug valproyl glycinamide

      EPILEPSIA
    26. Bronstrup, M; Schroder, D; Schwarz, H
      Oxidative dealkylation of aromatic amines by "bare" FeO+ in the gas phase

      CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE
    27. Wimalasena, K; Alliston, KR
      Mode of substrate interaction and energetics of carbon-oxygen bond formation of the dopamine beta-monooxygenase reaction

      BIOCHEMISTRY
    28. BIETTI M; CUPPOLETTI A; DAGOSTIN C; FLOREA C; GALLI C; GENTILI P; PETRIDE H; CAIA CR
      STEREOELECTRONIC INHIBITION OF DEPROTONATION IN THE RADICAL-CATION OFN-BENZYLPIPERIDINE - A CONTRIBUTION TO THE DEBATE ON THE MECHANISM OFN-DEALKYLATION OF TERTIARY-AMINES

      EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
    29. Zhao, ZY; Mabic, S; Kuttab, S; Franot, C; Castagnoli, K; Castagnoli, N
      Rat liver microsomal enzyme catalyzed oxidation of 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine

      BIOORGANIC & MEDICINAL CHEMISTRY
    30. OELSCHLAGER H; ROTHLEY D; KLINGER W; KARGE E; VOGELSANG H
      CHROMATOGRAPHIC RESOLUTION OF CIPROFIBRATE AND INTERACTION OF THE RACEMATE AND BOTH ENANTIOMERS WITH RAT-LIVER MICROSOMES IN-VITRO

      Experimental and toxicologic pathology
    31. YASSIR A; RIEU C; SOULAS G
      MICROBIAL N-DEALKYLATION OF ATRAZINE - EFFECT OF EXOGENEOUS ORGANIC SUBSTRATES AND BEHAVIOR OF THE SOIL MICROFLORA

      Pesticide science
    32. Hadley, MR; Oldham, HG; Damani, LA; Hutt, AJ
      High performance liquid chromatographic analysis of the in vitro N-dealkylated and N-oxide metabolites of N-ethyl-N-methylaniline: Methodology for the determination of enzyme activity and stereoselectivity of N-oxidation

      CHROMATOGRAPHIA
    33. RACHA JK; RETTIE AE; KUNZE KL
      MECHANISM-BASED INACTIVATION OF HUMAN CYTOCHROME-P450 1A2 BY FURAFYLLINE - DETECTION OF A 1 1-ADDUCT TO PROTEIN AND EVIDENCE FOR THE FORMATION OF A NOVEL IMIDAZOMETHIDE INTERMEDIATE/

      Biochemistry
    34. SHIN HS
      STEREOSELECTIVE METABOLISM OF FAMPROFAZONE IN HUMANS - N-DEALKYLATIONAND BETA-HYDROXYLATION AND P-HYDROXYLATION

      Chirality
    35. PEREZGILABERT M; SANCHEZFERRER A; GARCIACARMONA F
      OXIDATION OF AMINOPYRINE BY THE HYDROPEROXIDASE ACTIVITY OF LIPOXYGENASE - A NEW PROPOSED MECHANISM OF N-DEMETHYLATION

      Free radical biology & medicine
    36. KLINGER W; OELSCHLAGER H; KARGE E; ROTHLEY D
      INTERACTION OF CHLORMEZANONE WITH RAT-LIVER MICROSOMES AND ITS DEGRADATION

      European journal of drug metabolism and pharmacokinetics
    37. GHAHRAMANI P; ELLIS SW; LENNARD MS; RAMSAY LE; TUCKER GT
      CYTOCHROMES P450 MEDIATING THE N-DEMETHYLATION OF AMITRIPTYLINE

      British journal of clinical pharmacology
    38. ALZUET G; CASELLA L; VILLA ML; CARUGO O; GULLOTTI M
      COPPER MONOOXYGENASE MODELS - AROMATIC HYDROXYLATION BY A DINUCLEAR COPPER(I) COMPLEX CONTAINING METHIONINE SULFUR LIGANDS

      Journal of the Chemical Society. Dalton transactions
    39. BOUNDYMILLS KL; DESOUZA ML; MANDELBAUM RT; WACKETT LP; SADOWSKY MJ
      THE ATZB GENE OF PSEUDOMONAS SP STRAIN ADP ENCODES THE 2ND ENZYME OF A NOVEL ATRAZINE DEGRADATION PATHWAY

      Applied and environmental microbiology
    40. LIU D; MAGUIRE RJ; LAU YL; PACEPAVICIUS GJ; OKAMURA H; AOYAMA I
      TRANSFORMATION OF THE NEW ANTIFOULING COMPOUND IRGAROL-1051 BY PHANEROCHAETE-CHRYSOSPORIUM

      Water research
    41. MOUGIN C; LAUGERO C; ASTHER M; CHAPLAIN V
      BIOTRANSFORMATION OF S-TRIAZINE HERBICIDES AND RELATED DEGRADATION PRODUCTS IN LIQUID CULTURES BY THE WHITE-ROT FUNGUS PHANEROCHAETE-CHRYSOSPORIUM

      Pesticide science
    42. HANSCH C; GAO H
      COMPARATIVE QSAR - RADICAL REACTIONS OF BENZENE-DERIVATIVES IN CHEMISTRY AND BIOLOGY

      Chemical reviews
    43. KOTANI E; TAKEYA T; SHIMIZU H; EGAWA H; YAMAMOTO T; TOBINAGA S
      IRON(III) PICOLINATE-CATALYZED OXIDATIVE DEMETHYLATION OF N,N-DIMETHYLANILINE WITH HYDROGEN-PEROXIDE IN THE PRESENCE OF ACETIC-ANHYDRIDE

      Chemical and Pharmaceutical Bulletin
    44. WIMALASENA K; WIMALASENA DS; DHARMASENA S; HAINES DC; ALLISTON KR
      CHIRAL MULTISUBSTRATE INHIBITORS OF DOPAMINE BETA-MONOOXYGENASE - EVIDENCE FOR DUAL MODES OF INTERACTION

      Biochemistry
    45. MASAPHY S; LEVANON D; HENIS Y
      DEGRADATION OF ATRAZINE BY THE LIGNOCELLULOLYTIC FUNGUS PLEUROTUS-PULMONARIUS DURING SOLID-STATE FERMENTATION

      Bioresource technology
    46. SUWINSKI J; SZCZEPANKIEWICZ W
      SYNTHESIS OF 2-METHYL-4(5)-NITRO[N-15(1)((3))]IMIDAZOLE FROM 2-METHYL-4(5)-NITROIMIDAZOLE

      Journal of labelled compounds & radiopharmaceuticals
    47. ROWLAND K; ELLIS SW; LENNARD MS; TUCKER GT
      VARIABLE CONTRIBUTION OF CYP2D6 TO THE N-DEALKYLATION OF S-(-)-PROPRANOLOL BY HUMAN LIVER-MICROSOMES

      British journal of clinical pharmacology
    48. MAISH WA; HAMPTON EM; WHITSETT TL; SHEPARD JD; LOVALLO WR
      INFLUENCE OF GRAPEFRUIT JUICE ON CAFFEINE PHARMACOKINETICS AND PHARMACODYNAMICS

      Pharmacotherapy
    49. VONMOLTKE LL; GREENBLATT DJ; DUAN SX; HARMATZ JS; WRIGHT CE; SHADER RI
      INHIBITION OF TERFENADINE METABOLISM IN-VITRO BY AZOLE ANTIFUNGAL AGENTS AND BY SELECTIVE SEROTONIN REUPTAKE INHIBITOR ANTIDEPRESSANTS - RELATION TO PHARMACOKINETIC INTERACTIONS IN-VIVO

      Journal of clinical psychopharmacology
    50. SHAO ZQ; BEHKI R
      CHARACTERIZATION OF THE EXPRESSION OF THE THCB GENE, CODING FOR A PESTICIDE-DEGRADING CYTOCHROME-P-450 IN RHODOCOCCUS STRAINS

      Applied and environmental microbiology
    51. IRSHAID Y; BRANCH RA; ADEDOYIN A
      METABOLIC INTERACTIONS OF PUTATIVE CYTOCHROME P4503A SUBSTRATES WITH ALTERNATIVE PATHWAYS OF DAPSONE METABOLISM IN HUMAN LIVER-MICROSOMES

      Drug metabolism and disposition
    52. MAY SW; YOUNG FK; POWERS JL; GILLWOZNICHAK MM
      MECHANISM-BASED INACTIVATION OF DOPAMINE BETA-MONOOXYGENASE IN ADRENAL CHROMAFFIN CELLS

      Biochemical and biophysical research communications
    53. BACIOCCHI E; LANZALUNGA O; MALANDRUCCO S; IOELE M; STEENKEN S
      OXIDATION OF SULFIDES BY PEROXIDASES - INVOLVEMENT OF RADICAL CATIONSAND THE RATE OF THE OXYGEN REBOUND STEP

      Journal of the American Chemical Society
    54. HEGADOREN KM; BAKER GB; COUTTS RT
      ANALYSIS OF THE ENANTIOMERS OF 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE, EVE) AND ITS METABOLITE 3,4-METHYLENEDIOXYAMPHETAMINE (MDA) IN RAT-BRAIN

      Journal of pharmacological and toxicological methods
    55. GUENGERICH FP; BELL LC; OKAZAKI O
      INTERPRETATIONS OF CYTOCHROME-P450 MECHANISMS FROM KINETIC-STUDIES

      Biochimie
    56. SIRIMANNE SR; MAY SW
      INTERACTION OF NONCONJUGATED OLEFINIC SUBSTRATE-ANALOGS WITH DOPAMINEBETA-MONOOXYGENASE - CATALYSIS AND MECHANISM-BASED INHIBITION

      Biochemical journal
    57. KALGUTKAR AS; CASTAGNOLI N; TESTA B
      SELECTIVE INHIBITORS OF MONOAMINE-OXIDASE (MAO-A AND MAO-B) AS PROBESOF ITS CATALYTIC SITE AND MECHANISM

      Medicinal research reviews
    58. BALL SE; SCATINA JA; SISENWINE SF; FISHER GL
      THE APPLICATION OF IN-VITRO MODELS OF DRUG-METABOLISM AND TOXICITY INDRUG DISCOVERY AND DRUG DEVELOPMENT

      Drug and chemical toxicology
    59. NAGY I; COMPERNOLLE F; GHYS K; VANDERLEYDEN J; DEMOT R
      A SINGLE CYTOCHROME-P-450 SYSTEM IS INVOLVED IN DEGRADATION OF THE HERBICIDES EPTC (S-ETHYL DIPROPYLTHIOCARBAMATE) AND ATRAZINE BY RHODOCOCCUS SP STRAIN NI86 21/

      Applied and environmental microbiology
    60. CARLSON TJ; JONES JP; PETERSON L; CASTAGNOLI N; IYER KR; TRAGER WF
      STEREOSELECTIVITY AND ISOTOPE EFFECTS ASSOCIATED WITH CYTOCHROME P450-CATALYZED OXIDATION OF (S)-NICOTINE - THE POSSIBILITY OF INITIAL HYDROGEN ATOM ABSTRACTION IN THE FORMATION OF THE DELTA-1',5'-NICOTINIUM ION

      Drug metabolism and disposition
    61. VANZWIETEN L; KENNEDY IR
      RAPID DEGRADATION OF ATRAZINE BY RHODOCOCCUS SP NI86 21 AND BY AN ATRAZINE-PERFUSED SOIL/

      Journal of agricultural and food chemistry
    62. BENSOUSSAN C; DELAFORGE M; MANSUY D
      PARTICULAR ABILITY OF CYTOCHROMES P450 3A TO FORM INHIBITORY P450-IRON-METABOLITE COMPLEXES UPON METABOLIC OXIDATION OF AMINODRUGS

      Biochemical pharmacology
    63. WIMALASENA K; ALLISTON KR
      1-(2-AMINOETHYL)-1,4-CYCLOHEXADIENE - A PROBE TO EXAMINE THE CHEMISTRY AND ENERGETICS OF THE C-H BOND-CLEAVAGE IN DOPAMINE BETA-MONOOXYGENASE CATALYSIS

      Journal of the American Chemical Society
    64. GERSHBEIN LL
      HEPATOTROPHIC ACTIVITY OF BENZODIAZEPINE DRUGS IN ADULT-RATS OF EITHER SEX

      Research communications in molecular pathology and pharmacology
    65. COUTTS RT; SU P; BAKER GB
      INVOLVEMENT OF CYP2D6, CYP3A4, AND OTHER CYTOCHROME-P-450 ISOZYMES INN-DEALKYLATION REACTIONS

      Journal of pharmacological and toxicological methods
    66. MADYASTHA KM
      PREPARATIVELY USEFUL TRANSFORMATIONS OF STEROIDS AND MORPHINE ALKALOIDS BY MUCOR PIRIFORMIS

      Proceedings of the Indian Academy of Sciences. Chemical sciences
    67. LUCINI R; ORLANDI M; RINDONE B; SEBASTIANO R; TODESCHINI R
      FACTORS AFFECTING CYTOCHROME-P-450 AND HORSERADISH PEROXIDASE-CATALYZED OXIDATIVE N-DEALKYLATION OF AROMATIC TERTIARY-AMINES - A MULTIVARIATE APPROACH

      Journal of molecular catalysis
    68. SCHULTZ IR; HAYTON WL
      TOXICOKINETICS OF TRIFLURALIN IN RAINBOW-TROUT

      Aquatic toxicology


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/12/19 alle ore 01:45:58