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La ricerca find articoli where soggetti phrase all words 'MUTANT PRESENILIN-1' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 68 riferimenti
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    1. Calabrese, EJ
      Amyloid beta-peptide: Biphasic dose responses

      CRITICAL REVIEWS IN TOXICOLOGY
    2. Refolo, LM; Pappolla, MA; LaFrancois, J; Malester, B; Schmidt, SD; Thomas-Bryant, T; Tint, GS; Wang, R; Mercken, M; Petanceska, SS; Duff, KE
      A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenicmouse model of Alzheimer's disease

      NEUROBIOLOGY OF DISEASE
    3. Leissring, MA; LaFerla, FM; Callamaras, N; Parker, I
      Subcellular mechanisms of presenilin-mediated enhancement of calcium signaling

      NEUROBIOLOGY OF DISEASE
    4. Hartmann, D; Tournoy, J; Saftig, P; Annaert, W; De Strooper, B
      Implication of APP secretases in notch signaling

      JOURNAL OF MOLECULAR NEUROSCIENCE
    5. Vestling, M; Wiehager, B; Tanii, H; Cowburn, RF
      Akt activity in presenilin 1 wild-type and mutation transfected human SH-SY5Y neuroblastoma cells after serum deprivation and high glucose stress

      JOURNAL OF NEUROSCIENCE RESEARCH
    6. Popescu, BO; Cedazo-Minguez, A; Popescu, LM; Winblad, B; Cowburn, RF; Ankarcrona, M
      Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

      JOURNAL OF NEUROSCIENCE RESEARCH
    7. Matsuoka, Y; Picciano, M; La Francois, J; Duff, K
      Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse modelof Alzheimer's disease

      NEUROSCIENCE
    8. Pigino, G; Pelsman, A; Mori, H; Busciglio, J
      Presenilin-1 mutations reduce cytoskeletal association, deregulate neuritegrowth, and potentiate neuronal dystrophy and tau phosphorylation

      JOURNAL OF NEUROSCIENCE
    9. Mattson, MP; Chan, SL; Camandola, S
      Presenilin mutations and calcium signaling defects in the nervous and immune systems

      BIOESSAYS
    10. Lucas, JL; Hernandez, F; Gomez-Ramos, P; Moran, MA; Hen, R; Avila, J
      Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3 beta conditional transgenic mice

      EMBO JOURNAL
    11. Ishii, K; Lippa, C; Tomiyama, T; Miyatake, F; Ozawa, K; Tamaoka, A; Hasegawa, T; Fraser, PE; Shoji, S; Nee, LE; Pollen, DA; St George-Hyslop, PH; Ii, K; Ohtake, T; Kalaria, RN; Rossor, MN; Lantos, PL; Cairns, NJ; Farrer, LA; Mori, H
      Distinguishable effects of Presenilin-1 and APP717 mutations on amyloid plaque deposition

      NEUROBIOLOGY OF AGING
    12. Gordon, MN; King, DL; Diamond, DM; Jantzen, PT; Boyett, KV; Hope, CE; Hatcher, JM; DiCarlo, G; Gottschall, WPE; Morgan, D; Arendash, GW
      Correlation between cognitive deficits and A beta deposits in transgenic APP+PS1 mice

      NEUROBIOLOGY OF AGING
    13. Chapman, PF; Falinska, AM; Knevett, SG; Ramsay, MF
      Genes, models and Alzheimer's disease

      TRENDS IN GENETICS
    14. Le, R; Cruz, L; Urbanc, B; Knowles, RB; Hsiao-Ashe, K; Duff, K; Irizarry, MC; Stanley, HE; Hyman, BT
      Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: Implications for neural system disruption

      JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
    15. Nakajima, M; Miura, M; Aosaki, T; Shirasawa, T
      Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro

      JOURNAL OF NEUROCHEMISTRY
    16. Matsuoka, Y; Picciano, M; Malester, B; LaFrancois, J; Zehr, C; Daeschner, JM; Olschowka, JA; Fonseca, MI; O'Banion, MK; Tenner, AJ; Lemere, CA; Duff, K
      Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease

      AMERICAN JOURNAL OF PATHOLOGY
    17. Refolo, LM; Malester, B; LaFrancois, J; Bryant-Thomas, T; Wang, R; Tint, GS; Sambamurti, K; Duff, K; Pappolla, MA
      A high fat, high cholesterol diet accelerates beta-amyloid accumulation inthe CNS of a transgenic mouse model of Alzheimer's disease

      ALZHEIMER'S DISEASE
    18. Nixon, RA; Mathews, PM; Cataldo, AM; Mohan, PS; Schmidt, SD; Duff, K; Berg, M; Marks, N; Peterhoff, C; Sershen, H
      In vivo perturbation of lysosomal function promotes neuro-degeneration in the PS1(M146V)/APP(K670N,M671L) mouse model of Alzheimer's disease pathology

      ALZHEIMER'S DISEASE
    19. Van Uden, E; Kang, DE; Hoo, EH; Masliah, E
      LDL receptor-related protein (LRP) in Alzheimer's disease: Towards a unified theory of pathogenesis

      MICROSCOPY RESEARCH AND TECHNIQUE
    20. Yu, P; Oberto, G
      Alzheimer's disease: Transgenic mouse models and drug assessment

      PHARMACOLOGICAL RESEARCH
    21. Refolo, LM; Pappolla, MA; Malester, B; LaFrancois, J; Bryant-Thomas, T; Wang, R; Tint, GS; Sambamurti, K; Duff, K
      Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

      NEUROBIOLOGY OF DISEASE
    22. Kim, SH; Lah, JJ; Thinakaran, G; Levey, A; Sisodia, SS
      Subcellular localization of presenilins: Association with a unique membrane pool in cultured cells

      NEUROBIOLOGY OF DISEASE
    23. Fraser, PE; Yang, DS; Yu, G; Levesque, L; Nishimura, M; Arawaka, S; Serpell, LC; Rogaeva, E; St George-Hyslop, P
      Presenilin structure, function and role in Alzheimer disease

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    24. Janus, C; Chishti, MA; Westaway, D
      Transgenic mouse models of Alzheimer's disease

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    25. Golde, TE; Eckman, CB; Younkin, SG
      Biochemical detection of A beta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
    26. Mattson, MP
      Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy

      EXPERIMENTAL GERONTOLOGY
    27. Tanii, H; Ankarcrona, M; Flood, F; Nilsberth, C; Mehta, ND; Perez-Tur, J; Winblad, B; Benedikz, E; Cowburn, RF
      Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis

      NEUROSCIENCE
    28. Wengenack, TM; Whelan, S; Curran, GL; Duff, KE; Poduslo, JF
      Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain

      NEUROSCIENCE
    29. Czech, C; Tremp, G; Pradier, L
      Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms

      PROGRESS IN NEUROBIOLOGY
    30. Mattson, MP; Zhu, HY; Yu, J; Kindy, MS
      Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: Involvement of perturbed calcium homeostasis

      JOURNAL OF NEUROSCIENCE
    31. Siman, R; Reaume, AG; Savage, MJ; Trusko, S; Lin, YG; Scott, RW; Flood, DG
      Presenilin-1 P264L knock-in mutation: Differential effects on A beta production, amyloid deposition, and neuronal vulnerability

      JOURNAL OF NEUROSCIENCE
    32. Mucke, L; Masliah, E; Yu, GQ; Mallory, M; Rockenstein, EM; Tatsuno, G; Hu, K; Kholodenko, D; Johnson-Wood, K; McConlogue, L
      High-level neuronal expression of A beta(1-42) in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation

      JOURNAL OF NEUROSCIENCE
    33. Shoji, M; Iwakami, N; Takeuchi, S; Waragai, M; Suzuki, M; Kanazawa, I; Lippa, CF; Ono, S; Okazawa, H
      JNK activation is associated with intracellular beta-amyloid accumulation

      MOLECULAR BRAIN RESEARCH
    34. Xie, J; Guo, Q; Zhu, HY; Wooten, MW; Mattson, MP
      Protein kinase C iota protects neural cells against apoptosis induced by amyloid beta-peptide

      MOLECULAR BRAIN RESEARCH
    35. Morgan, D; Diamond, DM; Gottschall, PE; Ugen, KE; Dickey, C; Hardy, J; Duff, K; Jantzen, P; DiCarlo, G; Wilcock, D; Connor, K; Hatcher, J; Hope, C; Gordon, M; Arendash, GW
      A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

      NATURE
    36. Grilli, M; Lozza, G; Brusa, R; Casarini, M; Uberti, D; Rozmahel, R; Westaway, D; St George-Hyslop, P; Memo, M; Ongini, E
      Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    37. Barkats, M; Millecamps, S; Abrioux, P; Geoffroy, MC; Mallet, J
      Overexpression of glutathione peroxidase increases the resistance of neuronal cells to A beta-mediated neurotoxicity

      JOURNAL OF NEUROCHEMISTRY
    38. Kimberly, WT; Xia, WM; Rahmati, T; Wolfe, MS; Selkoe, DJ
      The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    39. Chan, SL; Mayne, M; Holden, CP; Geiger, JD; Mattson, MP
      Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons

      JOURNAL OF BIOLOGICAL CHEMISTRY
    40. Guo, Q; Xie, J; Du, HM
      Par-4 induces cholinergic hypoactivity by suppressing ChAT protein synthesis and inhibiting NGF-inducibility of ChAT activity

      BRAIN RESEARCH
    41. Emilien, G; Maloteaux, JM; Beyreuther, K; Masters, CL
      Alzheimer disease - Mouse models pave the way for therapeutic opportunities

      ARCHIVES OF NEUROLOGY
    42. Checler, F
      Presenilins: Multifunctional proteins involved in Alzheimer's disease pathology

      IUBMB LIFE
    43. Scheper, W; Annaert, W; Cupers, P; Saftig, P; De Strooper, B
      Function and dysfunction of the presenilins

      ALZHEIMERS REPORTS
    44. Stege, GJJ; Bosman, GJCGM
      The biochemistry of Alzheimer's disease

      DRUGS & AGING
    45. Chui, DH; Tanahashi, H; Ozawa, K; Ikeda, S; Checler, F; Ueda, O; Suzuki, H; Araki, W; Inoue, H; Shirotani, K; Takahashi, K; Gallyas, F; Tabira, T
      Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

      NATURE MEDICINE
    46. Parent, A; Linden, DJ; Sisodia, SS; Borchelt, DR
      Synaptic transmission and hippocampal long-term potentiation in transgenicmice expressing FAD-linked presenilin 1

      NEUROBIOLOGY OF DISEASE
    47. Fine, RE
      The biochemistry of Alzheimer disease

      ALZHEIMER DISEASE & ASSOCIATED DISORDERS
    48. Guo, Q; Fu, WM; Holtsberg, FW; Steiner, SM; Mattson, MP
      Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations

      JOURNAL OF NEUROSCIENCE RESEARCH
    49. Julliams, A; Vanderhoeven, I; Kuhn, S; Van Broeckhoven, C; De Jonghe, C
      No influence of presenilin 1 I143Tand G384A mutations on endogenous tau phosphorylation in human and mouse neuroblastoma cells

      NEUROSCIENCE LETTERS
    50. Wong, TP; Debeir, T; Duff, K; Cuello, AC
      Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-l and amyloid precursorprotein transgenes

      JOURNAL OF NEUROSCIENCE
    51. Guenette, SY; Tanzi, RE
      Progress toward valid transgenic mouse models for Alzheimer's disease

      NEUROBIOLOGY OF AGING
    52. Augelli-Szafran, CE; Walker, LC; LeVine, H
      beta-amyloid as a target for Alzheimer's disease therapy

      ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 34
    53. Guo, Q; Sebastian, L; Sopher, BL; Miller, MW; Glazner, GW; Ware, CB; Martin, GM; Mattson, MP
      Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    54. Kaltschmidt, B; Uherek, M; Wellmann, H; Volk, B; Kaltschmidt, C
      Inhibition of NF-kappa B potentiates amyloid beta-mediated neuronal apoptosis

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    55. Kovacs, DM; Mancini, R; Henderson, J; Na, SJ; Schmidt, SD; Kim, TW; Tanzi, RE
      Staurosporine-induced activation of caspase-3 is potentiated by presenilin1 familial Alzheimer's disease mutations in human neuroglioma cells

      JOURNAL OF NEUROCHEMISTRY
    56. Annaert, WG; Levesque, L; Craessaerts, K; Dierinck, I; Snellings, G; Westaway, D; George-Hyslop, PS; Cordell, B; Fraser, P; De Strooper, B
      Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-Golgi compartments of hippocampal neurons

      JOURNAL OF CELL BIOLOGY
    57. Stabler, SM; Ostrowski, LL; Janicki, SM; Monteiro, MJ
      A myristoylated calcium-binding protein that preferentially interacts withthe Alzheimer's disease presenilin 2 protein

      JOURNAL OF CELL BIOLOGY
    58. Nishimura, M; Yu, G; St George-Hyslop, PH
      Biology of presenilins as causative molecules for Alzheimer disease

      CLINICAL GENETICS
    59. Zhu, HY; Guo, Q; Mattson, MP
      Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation

      BRAIN RESEARCH
    60. Giannakopoulos, P; Kovari, E; Buee, L; Shioi, J; Hof, PR; Robakis, NK; Bouras, C
      Presenilin-1 expression in Pick's disease

      ACTA NEUROPATHOLOGICA
    61. Giannakopoulos, P; Kovari, E; Savioz, A; De Bilbao, F; Dubois-Dauphin, M; Hof, PR; Bouras, C
      Differential distribution of presenilin-1, Bax, and Bcl-X-L in Alzheimer'sdisease and frontotemporal dementia

      ACTA NEUROPATHOLOGICA
    62. Sisodia, SS; Thinakaran, G; Borchelt, DR; Wong, PC; Lee, MK; Price, DL
      Function and dysfunction of presenilins in Alzheimer's disease

      ALZHEIMER'S DISEASE AND RELATED DISORDERS
    63. GOATE AM
      MONOGENETIC DETERMINANTS OF ALZHEIMERS-DISEASE - APP MUTATIONS

      Cellular and molecular life sciences
    64. HARDY J; DUFF K; HARDY KG; PEREZTUR J; HUTTON M
      GENETIC DISSECTION OF ALZHEIMERS-DISEASE AND RELATED DEMENTIAS - AMYLOID AND ITS RELATIONSHIP TO TAU

      Nature neuroscience
    65. CITRON M; ECKMAN CB; DIEHL TS; CORCORAN C; OSTASZEWSKI BL; XIA WM; LEVESQUE G; HYSLOP PS; YOUNKIN SG; SELKOE DJ
      ADDITIVE EFFECTS OF PS1 AND APP MUTATIONS ON SECRETION OF THE 42-RESIDUE AMYLOID BETA-PROTEIN

      Neurobiology of disease
    66. Hsiao, K
      Transgenic mice expressing Alzheimer amyloid precursor proteins

      EXPERIMENTAL GERONTOLOGY
    67. ROSSNER S; UEBERHAM U; SCHLIEBS R; PEREZPOLO JR; BIGL V
      THE REGULATION OF AMYLOID PRECURSOR PROTEIN-METABOLISM BY CHOLINERGICMECHANISMS AND NEUROTROPHIN RECEPTOR SIGNALING

      Progress in neurobiology
    68. STEINER H; CAPELL A; PESOLD B; CITRON M; KLOETZEL PM; SELKOE DJ; ROMIG H; MENDLA K; HAASS C
      EXPRESSION OF ALZHEIMERS-DISEASE-ASSOCIATED PRESENILIN-1 IS CONTROLLED BY PROTEOLYTIC DEGRADATION AND COMPLEX-FORMATION

      The Journal of biological chemistry


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/05/20 alle ore 00:59:02