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La ricerca find articoli where soggetti phrase all words 'MUTAGENIC SUBSTRATE' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 72 riferimenti
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    1. Chang, DY; Gu, Y; Lu, AL
      Fission yeast (Schizosaccharomyces pombe) cells defective in the MutY-homologous glycosylase activity have a mutator phenotype and are sensitive to hydrogen peroxide

      MOLECULAR GENETICS AND GENOMICS
    2. Iida, T; Furuta, A; Kawashima, M; Nishida, J; Nakabeppu, Y; Iwaki, T
      Accumulation of 8-oxo-2 '-deoxyguanosine and increased expression of hMTH1protein in brain tumors

      NEURO-ONCOLOGY
    3. Nakabeppu, Y
      Molecular genetics and structural biology of human MutT homolog, MTH1

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    4. Kasprzak, KS; Nakabeppu, Y; Kakuma, T; Sakai, Y; Tsuruya, K; Sekiguchi, M; Ward, JM; Diwan, BA; Nagashima, K; Kasprzak, BH
      Intracellular distribution of the antimutagenic enzyme MTH1 in the liver, kidney and testis of F344 rats and its modulation by cadmium

      EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
    5. Suzuki, T; Masuda, M; Friesen, MD; Ohshima, H
      Formation of spiroiminodihydantoin nucleoside by reaction of 8-oxo-7,8-dihydro-2 '-deoxyguanosine with hypochlorous acid or a myeloperoxidase-H2O2-Cl- system

      CHEMICAL RESEARCH IN TOXICOLOGY
    6. Fujikawa, K; Kamiya, H; Yakushiji, H; Nakabeppu, Y; Kasai, H
      Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP

      NUCLEIC ACIDS RESEARCH
    7. Kim, HN; Morimoto, Y; Tsuda, T; Ootsuyama, Y; Hirohashi, M; Hirano, T; Tanaka, I; Lim, Y; Yun, IG; Kasai, H
      Changes in DNA 8-hydroxyguanine levels, 8-hydroxyguanine repair activity, and hOGG1 and hMTH1 mRNA expression in human lung alveolar epithelial cellsinduced by crocidolite asbestos

      CARCINOGENESIS
    8. Nakabeppu, Y
      Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage

      PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 68
    9. Nishimura, S
      Mammalian Ogg1/Mmh gene plays a major role in repair of the 8-hydroxyguanine lesion in DNA

      PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 68
    10. Tsuzuki, T; Egashira, A; Igarashi, H; Iwakuma, T; Nakatsura, Y; Tominaga, Y; Kawate, H; Nakao, K; Nakamura, K; Ide, F; Kura, S; Nakabeppu, Y; Katsuki, M; Ishikawa, T; Sekiguchi, M
      Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    11. Einolf, HJ; Guengerich, FP
      Fidelity of nucleotide insertion at 8-Oxo-7,8-dihydroguanine by mammalian DNA polymerase delta - Steady-state and pre-steady-state kinetic analysis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    12. Kamiya, H; Murata-Kamiya, N; Iida, E; Harashima, H
      Hydrolysis of oxidized nucleotides by the Escherichia coli Orf135 protein

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    13. Zhang, HZ; Xu, Y; Kamendulis, LM; Klaunig, JE
      Morphological transformation by 8-hydroxy-2 '-deoxyguanosine in Syrian hamster embryo (SHE) cells

      TOXICOLOGICAL SCIENCES
    14. Cooke, MS; Evans, MD; Herbert, KE; Lunec, J
      Urinary 8-oxo-2 '-deoxyguanosine - Source, significance and supplements

      FREE RADICAL RESEARCH
    15. Takama, F; Kanuma, T; Wang, D; Nishida, JI; Nakabeppu, Y; Wake, N; Mizunuma, H
      Mutation analysis of the hMTH1 gene in sporadic human ovarian cancer

      INTERNATIONAL JOURNAL OF ONCOLOGY
    16. Bialkowski, K; Kasprzak, KS
      Activity of the antimutagenic enzyme 8-oxo-2 '-deoxyguanosine 5 '-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) in cultured Chinese hamster ovarycells: Effects of cell cycle, proliferation rate, and population density

      FREE RADICAL BIOLOGY AND MEDICINE
    17. Ohtsubo, T; Nishioka, K; Imaiso, Y; Iwai, S; Shimokawa, H; Oda, H; Fujiwara, T; Nakabeppu, Y
      Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

      NUCLEIC ACIDS RESEARCH
    18. Shimokawa, H; Fujii, Y; Furuichi, M; Sekiguchi, M; Nakabeppu, Y
      Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein

      NUCLEIC ACIDS RESEARCH
    19. Meyer, F; Fiala, E; Westendorf, J
      Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress

      TOXICOLOGY
    20. Kasprzak, KS; Bialkowski, K
      Inhibition of antimutagenic enzymes, 8-oxo-dGTPases, by carcinogenic metals. Recent developments

      JOURNAL OF INORGANIC BIOCHEMISTRY
    21. Asagoshi, K; Yamada, T; Terato, H; Ohyama, Y; Monden, Y; Arai, T; Nishimura, S; Aburatani, H; Lindahl, T; Ide, H
      Distinct repair activities of human 7,8-dihydro-8 oxoguanine DNA glycosylase and formamidopyrimidine DNA glycosylase for formamidopyrimidine and 7,8-dihydro-8-oxoguanine

      JOURNAL OF BIOLOGICAL CHEMISTRY
    22. Miyako, K; Takamatsu, C; Umeda, S; Tajiri, T; Furuichi, M; Nakabeppu, Y; Sekiguchi, M; Hamasaki, N; Takeshige, K; Kang, D
      Accumulation of adenine DNA glycosylase-sensitive sites in human mitochondrial DNA

      JOURNAL OF BIOLOGICAL CHEMISTRY
    23. Harris, TK; Wu, G; Massiah, MA; Mildvan, AS
      Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase

      BIOCHEMISTRY
    24. Evans, MD; Cooke, MS; Akil, M; Samanta, A; Lunec, J
      Aberrant processing of oxidative DNA damage in systemic lupus erythematosus

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    25. Nishioka, K; Ohtsubo, T; Oda, H; Fujiwara, T; Kang, DC; Sugimachi, K; Nakabeppu, Y
      Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1mRNAs

      MOLECULAR BIOLOGY OF THE CELL
    26. Bialkowski, K; Bialkowska, A; Anderson, LM; Kasprzak, KS
      Higher activity of 8-oxo-2 '-deoxyguanosine 5 '-triphosphate pyrophosphohydrolase (8-oxo-dGTPase) coincides with lower background levels of 8-oxo-2 '-deoxyguanosine in DNA of fetal compared with maternal mouse organs

      FREE RADICAL BIOLOGY AND MEDICINE
    27. Oda, H; Taketomi, A; Maruyama, R; Itoh, R; Nishioka, K; Yakushiji, H; Suzuki, T; Sekiguchi, M; Nakabeppu, Y
      Multi-forms of human MTH1 polypeptides produced by alternative translationinitiation and single nucleotide polymorphism

      NUCLEIC ACIDS RESEARCH
    28. Gasmi, L; Cartwright, JL; McLennan, AG
      Cloning, expression and characterization of YSA1H, a human adenosine 5 '-diphosphosugar pyrophosphatase possessing a MutT motif

      BIOCHEMICAL JOURNAL
    29. Bialkowski, K; Bialkowska, A; Kasprzak, KS
      Cadmium(II), unlike nickel(II), inhibits 8-oxo-dGTPase activity and increases 8-oxo-dG level in DNA of the rat testis, a target organ for cadmium(II)carcinogenesis

      CARCINOGENESIS
    30. Fujii, Y; Shimokawa, H; Sekiguchi, M; Nakabeppu, Y
      Functional significance of the conserved residues for the 23-residue module among MTH1 and MutT family proteins

      JOURNAL OF BIOLOGICAL CHEMISTRY
    31. Fujikawa, K; Kamiya, H; Yakushiji, H; Fujii, Y; Nakabeppu, Y; Kasai, H
      The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    32. Hayakawa, H; Hofer, A; Thelander, L; Kitajima, S; Cai, Y; Oshiro, S; Yakushiji, H; Nakabeppu, Y; Kuwano, M; Sekiguchi, M
      Metabolic fate of oxidized guanine ribonucleotides in mammalian cells

      BIOCHEMISTRY
    33. LINN S
      DNA-DAMAGE BY IRON AND HYDROGEN-PEROXIDE IN-VITRO AND IN-VIVO

      Drug metabolism reviews
    34. ALAMO MJP; JURADO J; FRANCASTEL E; LAVAL F
      RAT 7,8-DIHYDRO-8-OXOGUANINE DNA GLYCOSYLASE - SUBSTRATE-SPECIFICITY,KINETICS AND CLEAVAGE MECHANISM AT AN APURINIC SITE

      Nucleic acids research
    35. BIALKOWSKI K; KASPRZAK KS
      A NOVEL ASSAY OF 8-OXO-2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE PYROPHOSPHOHYDROLASE (8-OXO-DGTPASE) ACTIVITY IN CULTURED-CELLS AND ITS USE FOR EVALUATION OF CADMIUM(II) INHIBITION OF THIS ACTIVITY

      Nucleic acids research
    36. WANI G; MILO GE; DAMBROSIO SM
      ENHANCED EXPRESSION OF THE 8-OXO-7,8-DIHYDRODEOXYGUANOSINE TRIPHOSPHATASE GENE IN HUMAN BREAST-TUMOR CELLS

      Cancer letters
    37. OHTSUBO T; MATSUDA O; IBA K; TERASHIMA I; SEKIGUCHI M; NAKABEPPU Y
      MOLECULAR-CLONING OF ATMMH, AN ARABIDOPSIS-THALIANA ORTHOLOG OF THE ESCHERICHIA-COLI MUTM GENE, AND ANALYSIS OF FUNCTIONAL DOMAINS OF ITS PRODUCT

      MGG. Molecular & general genetics
    38. OHANDLEY SF; FRICK DN; DUNN CA; BESSMAN MJ
      ORF186 REPRESENTS A NEW MEMBER OF THE NUDIX HYDROLASES, ACTIVE ON ADENOSINE(5')TRIPHOSPHO(5')ADENOSINE, ADP-RIBOSE, AND NADH

      The Journal of biological chemistry
    39. LU AL; FAWCETT WP
      CHARACTERIZATION OF THE RECOMBINANT MUTY HOMOLOG, AN ADENINE DNA GLYCOSYLASE, FROM YEAST SCHIZOSACCHAROMYCES-POMBE

      The Journal of biological chemistry
    40. SHEIKH S; OHANDLEY SF; DUNN CA; BESSMAN MJ
      IDENTIFICATION AND CHARACTERIZATION OF THE NUDIX HYDROLASE FROM THE ARCHAEON, METHANOCOCCUS-JANNASCHII, AS A HIGHLY SPECIFIC ADP-RIBOSE PYROPHOSPHATASE

      The Journal of biological chemistry
    41. COOKE MS; EVANS MD; PODMORE ID; HERBERT KE; MISTRY N; MISTRY P; HICKENBOTHAM PT; HUSSIENI A; GRIFFITHS HR; LUNEC J
      NOVEL REPAIR ACTION OF VITAMIN-C UPON IN-VIVO OXIDATIVE DNA-DAMAGE

      FEBS letters
    42. KENNEDY CH; CUETO R; BELINSKY SA; LECHNER JF; PRYOR WA
      OVEREXPRESSION OF HMTH1 MESSENGER-RNA - A MOLECULAR MARKER OF OXIDATIVE STRESS IN LUNG-CANCER CELLS

      FEBS letters
    43. Kwee, JK; Armelin, MS; Stefani, HA; Augusto, O
      Cell proliferation induced by 8-oxoguanosine and 8-methylguanosine, two adducts produced by free radical attack on ribonucleosides and RNA

      CHEMICO-BIOLOGICAL INTERACTIONS
    44. EINOLF HJ; SCHNETZBOUTAUD N; GUENGERICH FP
      STEADY-STATE AND PRE-STEADY-STATE KINETIC-ANALYSIS OF 8-OXO-7, 8-DIHYDROGUANOSINE TRIPHOSPHATE INCORPORATION AND EXTENSION BY REPLICATIVE AND REPAIR DNA-POLYMERASES

      Biochemistry
    45. SUMIDA S; DOI T; SAKURAI M; YOSHIOKA Y; OKAMURA K
      EFFECT OF A SINGLE BOUT OF EXERCISE AND BETA-CAROTENE SUPPLEMENTATIONON THE URINARY-EXCRETION OF 8-HYDROXY-DEOXYGUANOSINE IN HUMANS

      Free radical research
    46. LU RZ; NASH HM; VERDINE GL
      A MAMMALIAN DNA-REPAIR ENZYME THAT EXCISES OXIDATIVELY DAMAGED GUANINES MAPS TO A LOCUS FREQUENTLY LOST IN LUNG-CANCER

      Current biology
    47. YAKUSHIJI H; MARABOEUF F; TAKAHASHI M; DENG ZS; KAWABATA S; NAKABEPPU Y; SEKIGUCHI M
      BIOCHEMICAL AND PHYSICOCHEMICAL CHARACTERIZATION OF NORMAL AND VARIANT FORMS OF HUMAN MTH1 PROTEIN WITH ANTIMUTAGENIC ACTIVITY

      Mutation research. DNA repair
    48. IDE H; KOW YW; CHEN BX; ERLANGER BF; WALLACE SS
      ANTIBODIES TO OXIDATIVE DNA-DAMAGE - CHARACTERIZATION OF ANTIBODIES TO 8-OXOPURINES

      Cell biology and toxicology
    49. CAI JP; KAWATE H; IHARA K; YAKUSHIJI H; NAKABEPPU Y; TSUZUKI T; SEKIGUCHI M
      SIGNIFICANCE OF THE CONSERVED AMINO-ACID-SEQUENCE FOR HUMAN MTH1 PROTEIN WITH ANTIMUTATOR ACTIVITY

      Nucleic acids research
    50. LI AW; CATHERINE KTL; KNEE R; WILKINSON M; MURPHY PR
      FGF-2 ANTISENSE RNA ENCODES A NUCLEAR-PROTEIN WITH MUTT-LIKE ANTIMUTATOR ACTIVITY

      Molecular and cellular endocrinology
    51. BJORAS M; LUNA L; JOHNSON B; HOFF E; HAUG T; ROGNES T; SEEBERG E
      OPPOSITE BASE-DEPENDENT REACTIONS OF A HUMAN BASE EXCISION-REPAIR ENZYME ON DNA CONTAINING 7,8-DIHYDRO-8-OXOGUANINE AND ABASIC SITES

      EMBO journal
    52. PORTER DW; YAKUSHIJI H; NAKABEPPU Y; SEKIGUCHI M; FIVASH MJ; KASPRZAK KS
      SENSITIVITY OF ESCHERICHIA-COLI (MUTT) AND HUMAN (MTH1) 8-OXO-DGTPASES TO IN-VITRO INHIBITION BY THE CARCINOGENIC METALS, NICKEL(II), COPPER(II), COBALT(II) AND CADMIUM(II)

      Carcinogenesis
    53. TADDEI F; HAYAKAWA H; BOUTON MF; CIRINESI AM; MATIC I; SEKIGUCHI M; RADMAN M
      COUNTERACTION BY MUTT PROTEIN OF TRANSCRIPTIONAL ERRORS CAUSED BY OXIDATIVE DAMAGE

      Science
    54. IGARASHI H; TSUZUKI T; KAKUMA T; TOMINAGA Y; SEKIGUCHI M
      ORGANIZATION AND EXPRESSION OF THE MOUSE MTH1 GENE FOR PREVENTING TRANSVERSION MUTATION

      The Journal of biological chemistry
    55. LIN J; ABEYGUNAWARDANA C; FRICK DN; BESSMAN MJ; MILDVAN AS
      SOLUTION STRUCTURE OF THE QUATERNARY MUTT-M(2-AMPCPP-M(2+) COMPLEX AND MECHANISM OF ITS PYROPHOSPHOHYDROLASE ACTION())

      Biochemistry
    56. NASH HM; BRUNER SD; SCHARER OD; KAWATE T; ADDONA TA; SPONNER E; LANE WS; VERDINE GL
      CLONING OF A YEAST 8-OXOGUANINE DNA GLYCOSYLASE REVEALS THE EXISTENCEOF A BASE-EXCISION DNA-REPAIR PROTEIN SUPERFAMILY

      Current biology
    57. PORTER DW; NELSON VC; FIVASH MJ; KASPRZAK KS
      MECHANISTIC STUDIES OF THE INHIBITION OF MUTT DGTPASE BY THE CARCINOGENIC METAL NI(II)

      Chemical research in toxicology
    58. BESSMAN MJ; FRICK DN; OHANDLEY SF
      THE MUTT PROTEINS OR NUDIX HYDROLASES, A FAMILY OF VERSATILE, WIDELY DISTRIBUTED, HOUSECLEANING ENZYMES

      The Journal of biological chemistry
    59. SLUPSKA MM; BAIKALOV C; LUTHER WM; CHIANG JH; WEI YF; MILLER JH
      CLONING AND SEQUENCING A HUMAN HOMOLOG (HMYH) OF THE ESCHERICHIA-COLIMUTY GENE WHOSE FUNCTION IS REQUIRED FOR THE REPAIR OF OXIDATIVE DNA-DAMAGE

      Journal of bacteriology
    60. OKAMOTO K; TOYOKUNI S; KIM WJ; OGAWA O; KAKEHI Y; ARAO S; HIAI H; YOSHIDA O
      OVEREXPRESSION OF HUMAN MUTT HOMOLOG GENE MESSENGER-RNA IN RENAL-CELLCARCINOMA - EVIDENCE OF PERSISTENT OXIDATIVE STRESS IN CANCER

      International journal of cancer
    61. BULYCHEV NV; VARAPRASAD CV; DORMAN G; MILLER JH; EISENBERG M; GROLLMAN AP; JOHNSON F
      SUBSTRATE-SPECIFICITY OF ESCHERICHIA-COLI MUTY PROTEIN

      Biochemistry
    62. TAJIRI T; MAKI H; SEKIGUCHI M
      FUNCTIONAL COOPERATION OF MUTT, MUTM AND MUTY PROTEINS IN PREVENTING MUTATIONS CAUSED BY SPONTANEOUS OXIDATION OF GUANINE-NUCLEOTIDE IN ESCHERICHIA-COLI

      Mutation research. DNA repair
    63. MCGOLDRICK JP; YEH YC; SOLOMON M; ESSIGMANN JM; LU AL
      CHARACTERIZATION OF A MAMMALIAN HOMOLOG OF THE ESCHERICHIA-COLI MUTY MISMATCH REPAIR PROTEIN

      Molecular and cellular biology
    64. WANI G; DAMBROSIO SM
      CELL-TYPE-SPECIFIC EXPRESSION OF HUMAN 8-OXO-7,8-DIHYDROGUANOSINE TRIPHOSPHATASE IN NORMAL BREAST AND SKIN TISSUES IN-VIVO

      Carcinogenesis
    65. CAI JP; KAKUMA T; TSUZUKI T; SEKIGUCHI M
      CDNA AND GENOMIC SEQUENCES FOR RAT 8-OXO-DGTPASE THAT PREVENTS OCCURRENCE OF SPONTANEOUS MUTATIONS DUE TO OXIDATION OF GUANINE-NUCLEOTIDES

      Carcinogenesis
    66. KAKUMA T; NISHIDA J; TSUZUKI T; SEKIGUCHI M
      MOUSE MTH1 PROTEIN WITH 8-OXO-7,8-DIHYDRO-2'-DEOXYGUANOSINE 5'-TRIPHOSPHATASE ACTIVITY THAT PREVENTS TRANSVERSION MUTATION - CDNA CLONING AND TISSUE DISTRIBUTION

      The Journal of biological chemistry
    67. KANG D; NISHIDA J; IYAMA A; NAKABEPPU Y; FURUICHI M; FUJIWARA T; SEKIGUCHI M; TAKESHIGE K
      INTRACELLULAR-LOCALIZATION OF 8-OXO-DGTPASE IN HUMAN-CELLS, WITH SPECIAL REFERENCE TO THE ROLE OF THE ENZYME IN MITOCHONDRIA

      The Journal of biological chemistry
    68. ABEYGUNAWARDANA C; WEBER DJ; GITTIS AG; FRICK DN; LIN J; MILLER AF; BESSMAN MJ; MILDVAN AS
      SOLUTION STRUCTURE OF THE MUTT ENZYME, A NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE

      Biochemistry
    69. FRICK DN; WEBER DJ; ABEYGUNAWARDANA C; GITTIS AG; BESSMAN MJ; MILDVAN AS
      NMR-STUDIES OF THE CONFORMATIONS AND LOCATION OF NUCLEOTIDES BOUND TOTHE ESCHERICHIA-COLI MUTT ENZYME

      Biochemistry
    70. WU C; NAGASAKI H; MARUYAMA K; NAKABEPPU Y; SEKIGUCHI M; YUASA Y
      POLYMORPHISMS AND PROBABLE LACK OF MUTATION IN A HUMAN MUTT HOMOLOG, HMTH1, IN HEREDITARY NONPOLIPOSIS COLORECTAL-CANCER

      Biochemical and biophysical research communications
    71. FURUICHI M; YOSHIDA MC; ODA H; TAJIRI T; NAKABEPPU Y; TSUZUKI T; SEKIGUCHI M
      GENOMIC STRUCTURE AND CHROMOSOME LOCATION OF THE HUMAN MUTT HOMOLOG GENE MTH1 ENCODING 8-OXO-DGTPASE FOR PREVENTION OF A-T TO C-G TRANSVERSION

      Genomics
    72. MINNICK DT; PAVLOV YI; KUNKEL TA
      THE FIDELITY OF THE HUMAN LEADING AND LAGGING-STRAND DNA-REPLICATION APPARATUS WITH 8-OXODEOXYGUANOSINE TRIPHOSPHATE

      Nucleic acids research


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Documento generato il 13/08/20 alle ore 22:30:28