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La ricerca find articoli where soggetti phrase all words 'MECHANOTRANSDUCTION' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 291 riferimenti
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    1. Moalli, MR; Wang, SQ; Caldwell, NJ; Patil, PV; Maynard, CR
      Mechanical stimulation induces pp125(FAK) and pp60(src) activity in an in vivo model of trabecular bone formation

      JOURNAL OF APPLIED PHYSIOLOGY
    2. Berrios, JC; Schroeder, MA; Hubmayr, RD
      Mechanical properties of alveolar epithelial cells in culture

      JOURNAL OF APPLIED PHYSIOLOGY
    3. Roberts, SR; Knight, MM; Lee, DA; Bader, DL
      Mechanical compression influences intracellular Ca2+ signaling in chondrocytes seeded in agarose constructs

      JOURNAL OF APPLIED PHYSIOLOGY
    4. Sytkowski, AJ; Davis, KL
      Erythroid cell growth and differentiation in vitro in the simulated microgravity environment of the NASA rotating wall vessel bioreactor

      IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
    5. Endlich, N; Kress, KR; Reiser, J; Uttenweiler, D; Kriz, W; Mundel, P; Endlich, K
      Podocytes respond to mechanical stress in vitro

      JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
    6. Oswari, J; Matthay, MA; Margulies, SS
      Keratinocyte growth factor reduces alveolar epithelial susceptibility to in vitro mechanical deformation

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    7. Fisher, AB; Chien, S; Barakat, AI; Nerem, RM
      Endothelial cellular response to altered shear stress

      AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
    8. Gopfert, MG; Robert, D
      Active auditory mechanics in mosquitoes

      PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
    9. Tavernarakis, N; Everett, JK; Kyrpides, NC; Driscoll, M
      Structural and functional features of the intracellular amino terminus of DEG/ENaC ion channels

      CURRENT BIOLOGY
    10. Huber, A
      Scaffolding proteins organize multimolecular protein complexes for sensorysignal transduction

      EUROPEAN JOURNAL OF NEUROSCIENCE
    11. Viana, F; de la Pena, E; Pecson, B; Schmidt, RF; Belmonte, C
      Swelling-activated calcium signalling in cultured mouse primary sensory neurons

      EUROPEAN JOURNAL OF NEUROSCIENCE
    12. Loufrani, L; Matrougui, K; Li, ZL; Levy, BI; Lacolley, P; Paulin, D; Henrion, D
      Selective microvascular dysfunction in mice lacking the gene encoding for desmin

      FASEB JOURNAL
    13. Langevin, HM; Churchill, DL; Cipolla, MJ
      Mechanical signaling through connective tissue: a mechanism for the therapeutic effect of acupuncture

      FASEB JOURNAL
    14. Ryder, KD; Duncan, RL
      Parathyroid hormone enhances fluid shear-induced [Ca2+](i) signaling in osteoblastic cells through activation of mechanosensitive and voltage-sensitive Ca2+ channels

      JOURNAL OF BONE AND MINERAL RESEARCH
    15. Hsieh, YF; Robling, AG; Ambrosius, WT; Burr, DB; Turner, CH
      Mechanical loading of diaphyseal bone in vivo: The strain threshold for anosteogenic response varies with location

      JOURNAL OF BONE AND MINERAL RESEARCH
    16. Maxwell, CA; Hendzel, MJ
      The integration of tissue structure and nuclear function

      BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
    17. Kim, RD; Stein, GS; Chari, RS
      Impact of cell swelling on proliferative signal transduction in the liver

      JOURNAL OF CELLULAR BIOCHEMISTRY
    18. Saunders, MM; You, J; Trosko, JE; Yamasaki, H; Li, Z; Donahue, HJ; Jacobs, CR
      Gap junctions and fluid flow response in MC3T3-E1 cells

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    19. Donahue, SW; Jacobs, CR; Donahue, HJ
      Flow-induced calcium oscillations in rat osteoblasts are age, loading frequency, and shear stress dependent

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    20. Chen, JX; Fabry, B; Schiffrin, EL; Wang, N
      Twisting integrin receptors increases endothelin-1 gene expression in endothelial cells

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    21. Butler, PJ; Norwich, G; Weinbaum, S; Chien, S
      Shear stress induces a time- and position-dependent increase in endothelial cell membrane fluidity

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    22. Putnam, AJ; Schultz, K; Mooney, DJ
      Control of microtubule assembly by extracellular matrix and externally applied strain

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    23. Suvatne, J; Barakat, AI; O'Donnell, ME
      Flow-induced expression of endothelial Na-K-Cl cotransport: dependence on K+ and Cl- channels

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    24. Wei, ZH; Al-Mehdi, AB; Fisher, AB
      Signaling pathway for nitric oxide generation with simulated ischemia in flow-adapted endothelial cells

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    25. Bao, XP; Lu, CY; Frangos, JA
      Mechanism of temporal gradients in shear-induced ERK1/2 activation and proliferation in endothelial cells

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    26. Demaio, L; Chang, YS; Gardner, TW; Tarbell, JM; Antonetti, DA
      Shear stress regulates occludin content and phosphorylation

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    27. Sun, D; Huang, A; Sharma, S; Koller, A; Kaley, G
      Endothelial microtubule disruption blocks flow-dependent dilation of arterioles

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    28. Sun, D; Huang, A; Recchia, FA; Cui, Y; Messina, EJ; Koller, A; Kaley, G
      Nitric oxide-mediated arteriolar dilation after endothelial deformation

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    29. Satlin, LM; Sheng, SH; Woda, CB; Kleyman, TR
      Epithelial Na+ channels are regulated by flow

      AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
    30. Lye, SJ; Mitchell, J; Nashman, N; Oldenhof, A; Ou, R; Shynlova, O; Langille, L
      Role of mechanical signals in the onset of term and preterm labor

      ENDOCRINOLOGY OF PARTURITION: BASIC SCIENCE AND CLINICAL APPLICATION
    31. Garcia-Anoveros, J; Samad, TA; Zuvela-Jelaska, L; Woolf, CJ; Corey, DR
      Transport and localization of the DEG/ENaC ion channel BNaC1 alpha to peripheral mechanosensory terminals of dorsal root ganglia neurons

      JOURNAL OF NEUROSCIENCE
    32. Gale, JE; Marcotti, W; Kennedy, HJ; Kros, CJ; Richardson, GP
      FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel

      JOURNAL OF NEUROSCIENCE
    33. Poet, M; Tauc, M; Lingueglia, E; Cance, P; Poujeol, P; Lazdunski, M; Counillon, L
      Exploration of the pore structure of a peptide-gated Na+ channel

      EMBO JOURNAL
    34. Tzima, E; del Pozo, MA; Shattil, SJ; Chien, S; Schwartz, MA
      Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

      EMBO JOURNAL
    35. Huang, H; Kamm, RD; So, PTC; Lee, RT
      Receptor-based differences in human aortic smooth muscle cell membrane stiffness

      HYPERTENSION
    36. Zhang, J; Henrion, D; Ebrahimian, T; Benessiano, J; Colucci-Guyon, E; Langa, F; Levy, BI; Boulanger, CM
      Increased contribution of L-arginine-nitric oxide pathway in aorta of micelacking the gene for vimentin

      JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
    37. Bruinink, A; Siragusano, D; Ettel, G; Brandsberg, T; Brandsberg, F; Petitmermet, M; Muller, B; Mayer, J; Wintermantel, E
      The stiffness of bone marrow cell-knit composites is increased during mechanical load

      BIOMATERIALS
    38. Sikavitsas, VI; Temenoff, JS; Mikos, AG
      Biomaterials and bone mechanotransduction

      BIOMATERIALS
    39. John, K; Barakat, AI
      Modulation of ATP/ADP concentration at the endothelial surface by shear stress: Effect of flow-induced ATP release

      ANNALS OF BIOMEDICAL ENGINEERING
    40. Garcia-Cardena, G; Comander, J; Anderson, KR; Blackman, BR; Gimbrone, MA
      Biomechanical activation of vascular endothelium as a determinant of its functional phenotype

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    41. Wang, HB; Dembo, M; Hanks, SK; Wang, YL
      Focal adhesion kinase is involved in mechanosensing during fibroblast migration

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    42. Wang, N; Naruse, K; Stamenovic, D; Fredberg, JJ; Mijailovich, SM; Toric-Norrelykke, IM; Polte, T; Mannix, R; Ingber, DE
      Mechanical behavior in living cells consistent with the tensegrity model

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    43. Sun, D; Huang, A; Koller, A; Kaley, G
      Endothelial K-Ca channels mediate flow-dependent dilation of arterioles ofskeletal muscle and mesentery

      MICROVASCULAR RESEARCH
    44. Barakat, AI
      A model for shear stress-induced deformation of a flow sensor on the surface of vascular endothelial cells

      JOURNAL OF THEORETICAL BIOLOGY
    45. Koyama, T; Oike, M; Ito, Y
      Involvement of Rho-kinase and tyrosine kinase in hypotonic stress-induced ATP release in bovine aortic endothelial cells

      JOURNAL OF PHYSIOLOGY-LONDON
    46. Ohata, H; Tanaka, K; Maeyama, N; Yamamoto, M; Momose, K
      Visualization of elementary mechanosensitive Ca2+-influx events, Ca2+ spots, in bovine lens epithelial cells

      JOURNAL OF PHYSIOLOGY-LONDON
    47. Ishijima, M; Rittling, SR; Yamashita, T; Tsuji, K; Kurosawa, H; Nifuji, A; Denhardt, DT; Noda, M
      Enhancement of osteoclastic bone resorption and suppression of osteoblastic bone formation in response to reduced mechanical stress do not occur in the absence of osteopontin

      JOURNAL OF EXPERIMENTAL MEDICINE
    48. Robling, AG; Burr, DB; Turner, CH
      Recovery periods restore mechanosensitivity to dynamically loaded bone

      JOURNAL OF EXPERIMENTAL BIOLOGY
    49. Holtman, M; Thurm, U
      Variations of concentric hair cells in a cnidarian sensory epithelium (Coryne tubulosa)

      JOURNAL OF COMPARATIVE NEUROLOGY
    50. Geng, WD; Boskovic, G; Fultz, ME; Li, C; Niles, RM; Ohno, S; Wright, GL
      Regulation of expression and activity of four PKC isozymes in confluent and mechanically stimulated UMR-108 osteoblastic cells

      JOURNAL OF CELLULAR PHYSIOLOGY
    51. Edlich, M; Yellowley, CE; Jacobs, CR; Donahue, HJ
      Oscillating fluid flow regulates cytosolic calcium concentration in bovinearticular chondrocytes

      JOURNAL OF BIOMECHANICS
    52. Ohata, H; Tanaka, K; Maeyama, N; Ikeuchi, T; Kamada, A; Yamamoto, M; Momose, K
      Physiological and pharmacological role of lysophosphatidic acid as modulator in mechanotransduction

      JAPANESE JOURNAL OF PHARMACOLOGY
    53. Albuquerque, MLC; Flozak, AS
      Patterns of living beta-actin movement in wounded human coronary artery endothelial cells exposed to shear stress

      EXPERIMENTAL CELL RESEARCH
    54. Davis, ME; Cai, H; Drummond, GR; Harrison, DG
      Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways

      CIRCULATION RESEARCH
    55. Tanaka, H; Takamatsu, T
      Calcium spots - Elementary signals in response to mechanical stress in vascular eudothelial cells

      CIRCULATION RESEARCH
    56. Ohata, H; Ikeuchi, T; Kamada, A; Yamamoto, M; Momose, K
      Lysophosphatidic acid positively regulates the fluid flow-induced local Ca2+ influx in bovine aortic endothelial cells

      CIRCULATION RESEARCH
    57. Chrissobolis, S; Sobey, CG
      Evidence that Rho-kinase activity contributes to cerebral vascular tone invivo and is enhanced during chronic hypertension - Comparison with proteinkinase C

      CIRCULATION RESEARCH
    58. Redmond, EM; Cullen, JP; Cahill, PA; Sitzmann, JV; Stefansson, S; Lawrence, DA; Okada, SS
      Endothelial cells inhibit flow-induced smooth muscle cell migration - Roleof plasminogen activator inhibitor-1

      CIRCULATION
    59. Lacolley, P; Challande, P; Boumaza, S; Cohuet, G; Laurent, S; Boutouyrie, P; Grimaud, JA; Paulin, D; Lamaziere, JMD; Li, ZL
      Mechanical properties and structure of carotid arteries in mice lacking desmin

      CARDIOVASCULAR RESEARCH
    60. Kubis, N; Checoury, A; Tedgui, A; Levy, BI
      Adaptive common carotid arteries remodeling after unilateral internal carotid artery occlusion in adult patients

      CARDIOVASCULAR RESEARCH
    61. Babuty, D; Lab, MJ
      Mechanoelectric contributions to sudden cardiac death

      CARDIOVASCULAR RESEARCH
    62. Weinbaum, S; Guo, P; You, LD
      A new view of mechanotransduction and strain amplification in cells with microvilli and cell processes

      BIORHEOLOGY
    63. Secomb, TW; Hsu, R; Pries, AR
      Effect of the endothelial surface layer on transmission of fluid shear stress to endothelial cells

      BIORHEOLOGY
    64. Denhardt, DT; Burger, EH; Kazanecki, C; Krishna, S; Semeins, CM; Klein-Nulend, J
      Osteopontin-deficient bone cells are defective in their ability to produceNO in response to pulsatile fluid flow

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    65. Warden, SJ; Favaloro, JM; Bennell, KL; McMeeken, JM; Ng, KW; Zajac, JD; Wark, JD
      Low-intensity pulsed ultrasound stimulates a bone-forming response in UMR-106 cells

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    66. Chowdhury, TT; Bader, DL; Lee, DA
      Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1 beta-stimulated chondrocytes cultured in agarose constructs

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    67. Miyazaki, T; Ohata, H; Yamamoto, M; Momose, K
      Spontaneous and flow-induced Ca2+ transients in retracted regions in endothelial cells

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    68. Jin, M; Frank, EH; Quinn, TM; Hunziker, EB; Grodzinsky, AJ
      Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    69. Donahue, HJ
      Gap junctions and biophysical regulation of bone cell differentiation

      BONE
    70. Liu, MY; Post, M
      Invited review: Mechanochemical signal transduction in the fetal lung

      JOURNAL OF APPLIED PHYSIOLOGY
    71. Dos Santos, CC; Slutsky, AS
      Cellular responses to mechanical stress invited review: Mechanisms of ventilator-induced lung injury: a perspective

      JOURNAL OF APPLIED PHYSIOLOGY
    72. Ingber, DE; Heidemann, SR; Lamoureux, P; Buxbaum, RE
      Opposing views on tensegrity as a structural framework for understanding cell mechanics

      JOURNAL OF APPLIED PHYSIOLOGY
    73. Heidemann, SR; Lamoureaux, P; Buxbaum, RE
      Opposing views on tensegrity as a structural framework for understanding cell mechanics

      JOURNAL OF APPLIED PHYSIOLOGY
    74. Felix, JA; Dirksen, ER; Woodruff, ML
      PKC activation inhibits Ca2+ signaling in tracheal epithelial cells kept in simulated microgravity

      JOURNAL OF APPLIED PHYSIOLOGY
    75. Asthagiri, AR; Lauffenburger, DA
      Bioengineering models of cell signaling

      ANNUAL REVIEW OF BIOMEDICAL ENGINEERING
    76. Grodzinsky, AJ; Levenston, ME; Jin, M; Frank, EH
      Cartilage tissue remodeling in response to mechanical forces

      ANNUAL REVIEW OF BIOMEDICAL ENGINEERING
    77. Weatherby, TM; Lenz, PH
      Mechanoreceptors in calanoid copepods: designed for high sensitivity

      ARTHROPOD STRUCTURE & DEVELOPMENT
    78. Schiffers, PMH; Henrion, D; Boulanger, CM; Colucci-Guyon, E; Langa-Vuves, F; van Essen, H; Fazzi, GE; Levy, BI; De Mey, JGR
      Altered flow-induced arterial remodeling in vimentin-deficient mice

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    79. Millward-Sadler, SJ; Wright, MO; Lee, HS; Caldwell, H; Nuki, G; Salter, DM
      Altered electrophysiological responses to mechanical stimulation and abnormal signalling through alpha 5 beta 1 integrin in chondrocytes from osteoarthritic cartilage

      OSTEOARTHRITIS AND CARTILAGE
    80. Xu, QB
      Biomechanical-stress-induced signaling and gene expression in the development of arteriosclerosis

      TRENDS IN CARDIOVASCULAR MEDICINE
    81. Marchenko, SM; Sage, SO
      Effects of shear stress on [Ca2+](i) and membrane potential of vascular endothelium of intact rat blood vessels

      EXPERIMENTAL PHYSIOLOGY
    82. Huson, A
      Anatomy 2000: On the threshold of a new millennium

      EUROPEAN JOURNAL OF MORPHOLOGY
    83. Pawson, L; Slepecky, NB; Bolanowski, SJ
      Immunocytochemical identification of proteins within the Pacinian corpuscle

      SOMATOSENSORY AND MOTOR RESEARCH
    84. Salter, DM; Wallace, WHB; Robb, JE; Caldwell, H; Wright, MO
      Human bone cell hyperpolarization response to cyclical mechanical strain is mediated by an interleukin-1 beta autocrine/paracrine loop

      JOURNAL OF BONE AND MINERAL RESEARCH
    85. Lee, HS; Millward-Sadler, SJ; Wright, MO; Nuki, G; Salter, DM
      Integrin and mechanosensitive ion channel-dependent tyrosine phosphorylation of focal adhesion proteins and beta-catenin in human articular chondrocytes after mechanical stimulation

      JOURNAL OF BONE AND MINERAL RESEARCH
    86. Moalli, MR; Caldwell, NJ; Patil, PV; Goldstein, SA
      An in vivo model for investigations of mechanical signal transduction in trabecular bone

      JOURNAL OF BONE AND MINERAL RESEARCH
    87. Yellowley, CE; Li, ZY; Zhou, ZY; Jacobs, CR; Donahue, HJ
      Functional gap junctions between osteocytic and osteoblastic cells

      JOURNAL OF BONE AND MINERAL RESEARCH
    88. Lee, RT; Huang, H
      Mechanotransduction and arterial smooth muscle cells: new insight into hypertension and atherosclerosis

      ANNALS OF MEDICINE
    89. Ogata, T
      Fluid flow-induced tyrosine phosphorylation and participation of growth factor signaling pathway in osteoblast-like cells

      JOURNAL OF CELLULAR BIOCHEMISTRY
    90. Wang, HB; Dembo, M; Wang, YL
      Substrate flexibility regulates growth and apoptosis of normal but not transformed cells

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    91. An, SS; Hai, CM
      Mechanical signals and mechanosensitive modulation of intracellular [Ca2+]in smooth muscle

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    92. Bennett, SH; Eldridge, MW; Zaghi, D; Zaghi, SE; Milstein, JM; Goetzman, BW
      Form and function of fetal and neonatal pulmonary arterial bifurcations

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    93. Bao, XP; Clark, CB; Frangos, JA
      Temporal gradient in sheer-induced signaling pathway: involvement of MAP kinase, c-fos, and connexin43

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    94. Park, H; Go, YM; Darji, R; Choi, JW; Lisanti, MP; Maland, MC; Jo, H
      Caveolin-1 regulates sheer stress-dependent activation of extracellular signal-regulated kinase

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    95. Hill, MA; Zou, H; Davis, MJ; Potocnik, SJ; Price, S
      Transient increases in diameter and [Ca2+](i) are not obligatory for myogenic constriction

      AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    96. Khalsa, PS; Zhang, C; Sommerfeldt, D; Hadjiargyrou, M
      Expression of integrin alpha 2 beta 1 in axons and receptive endings of neurons in rat, hairy skin

      NEUROSCIENCE LETTERS
    97. Collinsworth, AM; Torgan, CE; Nagda, SN; Rajalingam, RJ; Kraus, WE; Truskey, GA
      Orientation and length of mammalian skeletal myocytes in response to a unidirectional stretch

      CELL AND TISSUE RESEARCH
    98. Fricke, B; Lints, R; Stewart, G; Drummond, H; Dodt, G; Driscoll, M; von During, M
      Epithelial Na+ channels and stomatin are expressed in rat trigeminal mechanosensory neurons

      CELL AND TISSUE RESEARCH
    99. Tanabe, Y; Saito, M; Ueno, A; Nakamura, M; Takeishi, K; Nakayama, K
      Mechanical stretch augments PDGF receptor beta expression and protein tyrosine phosphorylation in pulmonary artery tissue and smooth muscle cells

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    100. Klaus, D
      Atherosclerosis and arteriosclerosis in hypertension

      NIEREN-UND HOCHDRUCKKRANKHEITEN


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Documento generato il 30/10/20 alle ore 13:57:41