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PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex
GENES TO CELLS
Mutation in the prp12(+) gene encoding a homolog of SAP130/SF3b130 causes differential inhibition of pre-mRNA splicing and arrest of cell-cycle progression in Schizosaccharomyces pombe
RNA-A PUBLICATION OF THE RNA SOCIETY
Overexpression of caspase-1 in pancreatic disorders: Implications for a function besides apoptosis
JOURNAL OF GASTROINTESTINAL SURGERY
Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity
CURRENT OPINION IN CELL BIOLOGY
Apoptosis induction in prostate cancer cells by a novel gene product, pHyde, involves caspase-3
ONCOGENE
Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria
NUCLEIC ACIDS RESEARCH
Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a Src kinase pathway
MOLECULAR AND CELLULAR BIOLOGY
Translation initiation control by heme-regulated eukaryotic initiation factor 2 alpha kinase in erythroid cells under cytoplasmic stresses
MOLECULAR AND CELLULAR BIOLOGY
Glial cell development in the Drosophila embryo
BIOESSAYS
Heme-regulated eIF2 alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency
EMBO JOURNAL
The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
EMBO JOURNAL
Deficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed rats
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Chronicles of a switch hunt: gcm genes in development
TRENDS IN GENETICS
Familial isolated hypoparathyroidism caused by a mutation in the gene for the transcription factor GCMB
JOURNAL OF CLINICAL INVESTIGATION
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2 alpha
JOURNAL OF CELL BIOLOGY
Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent N-alpha-tosyl-1-phenylalanyl chloromethyl ketone
JOURNAL OF BIOLOGICAL CHEMISTRY
IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or I kappa B kinase but is blocked by vaccinia virus E3L protein
JOURNAL OF BIOLOGICAL CHEMISTRY
Limited proteolysis of filamin is catalyzed by caspase-3 in U937 and Jurkat cells
JOURNAL OF BIOCHEMISTRY
Inhibition of caspase-3-like activity reduces glutamate induced cell deathin adult rat retina
BRAIN RESEARCH
Human centromeres and neocentromeres show identical distribution patterns of > 20 functionally important kinetochore-associated proteins
HUMAN MOLECULAR GENETICS
Caspase-3/CPP32 immunoreactivity and its correlation with frequency of apoptotic bodies in human prostatic carcinomas and benign nodular hyperplasias
HISTOPATHOLOGY
Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry
EMBO JOURNAL
Monitoring activity of caspases and their regulators in yeast Saccharomyces cerevisiae
APOPTOSIS
Transient transfection assay of cell death genes
APOPTOSIS
Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Wild-type p53-dependent etoposide-induced apoptosis mediated by caspase-3 activation in human glioma cells
JOURNAL OF NEUROSURGERY
Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Involvement of the ubiquitin-proteasome pathway in the degradation of nontyrosine kinase-type cytokine receptors of IL-9, IL-2, and erythropoietin
JOURNAL OF IMMUNOLOGY
Inhibition of insulin-induced glucose uptake by atypical protein kinase C isotype-specific interacting protein in 3T3-L1 adipocytes
JOURNAL OF BIOLOGICAL CHEMISTRY
The prodomain of caspase-1 enhances Fas-mediated apoptosis through facilitation of caspase-8 activation
JOURNAL OF BIOLOGICAL CHEMISTRY
Structure, expression, and function of the Xenopus laevis caspase family
JOURNAL OF BIOLOGICAL CHEMISTRY
Morphological changes in the nucleus and actin cytoskeleton in the processof Fas-induced apoptosis in Jurkat T cells
HISTOCHEMICAL JOURNAL
Rapid upregulation of caspase-3 in rat spinal cord after injury: mRNA, protein, and cellular localization correlates with apoptotic cell death
EXPERIMENTAL NEUROLOGY
Ubiquitin-dependent protein processing controls radiation-induced apoptosis through the N-end rule pathway
EXPERIMENTAL CELL RESEARCH
Interferon-gamma-induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8-dependent activation of caspase 3 family members
BLOOD
Regulation of phosphatidylserine exposure and phagocytosis of apoptotic T lymphocytes
CELL DEATH AND DIFFERENTIATION
Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells
ONCOLOGY REPORTS
Mutations in FL5.12 cells conferring resistance to apoptosis induced by interleukin-3 deprivation
INTERNATIONAL JOURNAL OF ONCOLOGY
Role of caspases and possible involvement of retinoblastoma protein duringTGF beta-mediated apoptosis of human B lymphocytes
ONCOGENE
C-elegans MAC-1, an essential member of the AAA family of ATPases, can bind CED-4 and prevent cell death
DEVELOPMENT
Proteolytic activation of protein kinase C delta and epsilon by caspase-3 in U937 cells during chemotherapeutic agent-induced apoptosis
CELLULAR SIGNALLING
A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development
GENES & DEVELOPMENT
Recruitment of apoptotic cysteine proteases (caspases) in influenza virus-induced cell death
MICROBIOLOGY AND IMMUNOLOGY
Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade
NEUROSCIENCE
Endogenous inhibitors of caspases
JOURNAL OF CLINICAL IMMUNOLOGY
Activation of caspase-3-like proteases in apoptosis induced by sphingosineand other long-chain bases in Hep3B hepatoma cells
BIOCHEMICAL JOURNAL
Fas-mediated apoptosis in T cells involves the dephosphorylation of the retinoblastoma protein by type 1 protein phosphatases
HUMAN IMMUNOLOGY
Molecular cloning and biochemical characterization of a VCP homolog in African trypanosomes
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1
JOURNAL OF IMMUNOLOGY
Chromatin-association of the Polycomb group protein BMI1 is cell cycle-regulated and correlates with its phosphorylation status
JOURNAL OF CELL SCIENCE
Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1
JOURNAL OF BIOLOGICAL CHEMISTRY
The mouse p97 (CDC48) gene - Genomic structure, definition of transcriptional regulatory sequences, gene expression, and characterization of a pseudogene
JOURNAL OF BIOLOGICAL CHEMISTRY
Insulin-like growth factor-I prevents apoptosis in sympathetic neurons exposed to high glucose
HORMONE AND METABOLIC RESEARCH
Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3
GENETICS
Caspase-1 is not involved in CD95/Fas-induced apoptosis in Jurkat T cells
EXPERIMENTAL CELL RESEARCH
Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis
CANCER RESEARCH
Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: Overexpression of caspase-7 as a new gene therapy strategy for prostate cancer
CANCER RESEARCH
Liposomal ET-18-OCH3 induces cytochrome c-mediated apoptosis independentlyof CD95 (APO-1/Fas) signaling
BLOOD
The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G
BLOOD
WORTMANNIN ENHANCES ACTIVATION OF CPP32 (CASPASE-3) INDUCED BY TNF ORANTI-FAS
Cell death and differentiation
Investigation of glucocorticoid-induced apoptotic pathway: Processing of Caspase-6 but not Caspase-3
CELL DEATH AND DIFFERENTIATION
ACTIVATION OF INTERLEUKIN-1-BETA-CONVERTING ENZYME BY NIGERICIN IS INDEPENDENT OF APOPTOSIS
Cytokine (Philadelphia, Pa. Print)
INVOLVEMENT OF CASPASE FAMILY PROTEASES IN FPT INHIBITOR III-INDUCED APOPTOSIS IN HUMAN OVARIAN-CANCER CELLS
International journal of oncology
Biological role of SCC antigen
TUMOR BIOLOGY
ENHANCEMENT OF CHEMOSENSITIVITY TOWARD ANTICANCER DRUGS BY HIGH EXPRESSION OF CASPASE-1 IN NIH 3T3 CELLS
Anti-cancer drugs
ACCELERATION OF APOPTOTIC CELL-DEATH AFTER THE CLEAVAGE OF BCL-X-L PROTEIN BY CASPASE-3-LIKE PROTEASES
Oncogene
SIGNALING BY PROTEOLYSIS - DEATH RECEPTORS INDUCE APOPTOSIS
International journal of clinical & laboratory research
TRANSFORMING GROWTH-FACTOR-BETA-1 POTENTLY ACTIVATES CPP32-LIKE PROTEASES IN HUMAN HEPATOMA-CELLS
Cellular signalling
PEROXYNITRITE INDUCES APOPTOSIS OF HL-60 CELLS BY ACTIVATION OF A CASPASE-3 FAMILY PROTEASE
American journal of physiology. Cell physiology
IDENTIFICATION OF GENE FAMILY OF CASPASES IN RAT-KIDNEY AND ALTERED EXPRESSION IN ISCHEMIA-REPERFUSION INJURY
American journal of physiology. Renal, fluid and electrolyte physiology
NEED FOR CASPASE-2 IN APOPTOSIS OF GROWTH-FACTOR-DEPRIVED PC12 CELLS
Journal of neuroscience research
The fission yeast prp10(+) gene involved in pre-mRNA splicing encodes a homologue of highly conserved splicing factor, SAP155
NUCLEIC ACIDS RESEARCH
CASPASE PROTEASES MEDIATE APOPTOSIS INDUCED BY ANTICANCER AGENT PREACTIVATED MC540 IN HUMAN TUMOR-CELL LINES
Cancer letters
IDENTIFICATION OF BCAR3 BY A RANDOM SEARCH FOR GENES INVOLVED IN ANTIESTROGEN RESISTANCE OF HUMAN BREAST-CANCER CELLS
EMBO journal
MITOCHONDRIAL CYTOCHROME-C RELEASE IN APOPTOSIS OCCURS UPSTREAM OF DEVD-SPECIFIC CASPASE ACTIVATION AND INDEPENDENTLY OF MITOCHONDRIAL TRANSMEMBRANE DEPOLARIZATION
EMBO journal
Immunohistochemistry of Caspase3/CPP32 in human stomach and its correlation with cell proliferation and apoptosis
ANTICANCER RESEARCH
Anti-Fas antibody differentially regulates apoptosis in Fas ligand resistant carcinoma lines via the caspase 3 family of cell death proteases but independently of bcl2 expression
ANTICANCER RESEARCH
EXPRESSION OF NEDD2 ICH-1 (CASPASE-2) IN THE DEVELOPING RAT RETINA/
Neuroscience research
LYMPHOCYTE GRANULE-MEDIATED APOPTOSIS - MATTERS OF VIRAL MIMICRY AND DEADLY PROTEASES
Immunology today
MURINE CASPASE-11, AN ICE-INTERACTING PROTEASE, IS ESSENTIAL FOR THE ACTIVATION OF ICE
Cell
APOPTOSIS OF MOTOR-NEURONS WITH INDUCTION OF CASPASES IN THE SPINAL-CORD AFTER ISCHEMIA
Stroke
Molecular cloning and identification of murine caspase-8
JOURNAL OF MOLECULAR BIOLOGY
PARTIAL-PURIFICATION AND CHARACTERIZATION OF 2 DISTINCT TYPES OF CASPASES FROM HUMAN EPIDERMIS
Journal of investigative dermatology
GRANULYSIN-INDUCED APOPTOSIS - I - INVOLVEMENT OF AT LEAST 2 DISTINCTPATHWAYS
The Journal of immunology (1950)
APOPTOSIS MEDIATED BY FAS BUT NOT TUMOR-NECROSIS-FACTOR RECEPTOR-1 PREVENTS CHRONIC DISEASE IN MICE INFECTED WITH MURINE CYTOMEGALOVIRUS
The Journal of clinical investigation
CAPTURING NOVEL MOUSE GENES ENCODING CHROMOSOMAL AND OTHER NUCLEAR PROTEINS
Journal of Cell Science
TRANSITION FROM CASPASE-DEPENDENT TO CASPASE-INDEPENDENT MECHANISMS AT THE ONSET OF APOPTOTIC EXECUTION
The Journal of cell biology
REGULATION OF PROTEIN PHOSPHATASE 2A ACTIVITY BY CASPASE-3 DURING APOPTOSIS
The Journal of biological chemistry
CERAMIDE FORMATION LEADS TO CASPASE-3 ACTIVATION DURING HYPOXIC PC12 CELL-DEATH - INHIBITORY EFFECTS OF BCL-2 ON CERAMIDE FORMATION AND CASPASE-3 ACTIVATION
The Journal of biological chemistry
Shigella-induced apoptosis is dependent on Caspase-1 which binds to IpaB
JOURNAL OF BIOLOGICAL CHEMISTRY
INVOLVEMENT OF BOTH CASPASE-LIKE PROTEASES AND SERINE PROTEASES IN APOPTOTIC CELL-DEATH INDUCED BY RICIN, MODECCIN, DIPHTHERIA-TOXIN, AND PSEUDOMONAS TOXIN
Journal of Biochemistry (Tokyo)
PEROXYNITRITE-INDUCED THYMOCYTE APOPTOSIS - THE ROLE OF CASPASES AND POLY (ADP-RIBOSE) SYNTHETASE (PARS) ACTIVATION
Immunology
SELECTIVE INVOLVEMENT OF CASPASE-3 IN CERAMIDE INDUCED APOPTOSIS IN AK-5 TUMOR-CELLS
FEBS letters
CASPASE 7-INDUCED CLEAVAGE OF KINECTIN IN APOPTOTIC CELLS
FEBS letters
APOPTOTIC CELL-DEATH OF CULTURED CEREBRAL CORTICAL-NEURONS INDUCED BYWITHDRAWAL OF ASTROGLIAL TROPHIC SUPPORT
Experimental neurology
Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2
EXPERIMENTAL CELL RESEARCH
INHIBITION OF CPP32 BLOCKS SURFACE IGM-MEDIATED APOPTOSIS AND D4-GDI CLEAVAGE IN HUMAN BL60 BURKITT-LYMPHOMA CELLS
European Journal of Immunology
APOPTOSIS AND GENE-REGULATION
Current Science (Bangalore)
MODULATION BY PROINFLAMMATORY CYTOKINES OF FAS FAS LIGAND-MEDIATED APOPTOTIC CELL-DEATH OF SYNOVIAL-CELLS IN PATIENTS WITH RHEUMATOID-ARTHRITIS (RA)/
Clinical and experimental immunology