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BI Lyncis: A hydrogen-deficient binary consisting of two low-mass giants of spectral types early-B and G
ASTRONOMY & ASTROPHYSICS
Period and amplitude variations in the high-amplitude delta Scuti star AE Ursae Majoris
ASTRONOMY & ASTROPHYSICS
B-cell kinase Lyn deficiency in patients with systemic lupus erythematosus
JOURNAL OF INVESTIGATIVE MEDICINE
Murine lupus genetics: lessons learned
CURRENT OPINION IN RHEUMATOLOGY
Piceatannol is an effective inhibitor of IgE-mediated secretion from humanbasophils but is neither selective for this receptor nor acts on syk kinase at concentrations where mediator release inhibition occurs
CLINICAL AND EXPERIMENTAL ALLERGY
Apoptotic response of eosinophils in chronic eosinophilic pneumonia
EUROPEAN RESPIRATORY JOURNAL
B cell receptor signaling and autoimmunity
FASEB JOURNAL
Expression of B cell receptor-associated signaling molecules in human lupus
AUTOIMMUNITY
Regulation of the very late antigen-4-mediated adhesive activity of normaland nonreleaser basophils: roles for Src, Syk, and phosphatidylinositol 3-kinase
JOURNAL OF LEUKOCYTE BIOLOGY
Characteristics of the free cytosolic calcium timelag following IgE-mediated stimulation of human basophils: significance for the nonreleasing basophil phenotype
JOURNAL OF LEUKOCYTE BIOLOGY
B cell development pathways
ANNUAL REVIEW OF IMMUNOLOGY
Suppression of apoptosis and granulocyte colony-stimulating factor-induceddifferentiation by an oncogenic form of Cbl
EXPERIMENTAL HEMATOLOGY
Stem cell factor prevents Fas-mediated apoptosis of human erythroid precursor cells with Src-family kinase dependency
EXPERIMENTAL HEMATOLOGY
Recent progress in the understanding of B-cell functions in autoimmunity
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
A unique role for fyn in CNS myelination
JOURNAL OF NEUROSCIENCE
beta-Amyloid stimulation of microglia and monocytes results in TNF alpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
JOURNAL OF NEUROSCIENCE
Ubiquitination of Lyn-kinase in rat basophilic leukemia RBL-2H3 cells
IMMUNOLOGY LETTERS
Controlling allergic inflammation by signaling regulation of eosinophils
ALLERGY
Signal transduction by the high-affinity immunoglobulin E receptor Fc epsilon RI: Coupling form to function
ADVANCES IN IMMUNOLOGY, VOL. 76
Mechanisms of human neutrophil oxidant production after severe injury
SURGERY
Immunoseparation of sphingolipid-enriched membrane domains enriched in Srcfamily protein tyrosine kinases and in the neuronal adhesion molecule TAG-1 by anti-GD3 ganglioside monoclonal antibody
JOURNAL OF NEUROCHEMISTRY
Overcoming the signaling defect of Lyn-sequestering, signal-curtailing Fc epsilon RI dimers: Aggregated dimers can dissociate from Lyn and form signaling complexes with Syk
JOURNAL OF IMMUNOLOGY
CD19 can regulate B lymphocyte signal transduction independent of complement activation
JOURNAL OF IMMUNOLOGY
Negative control of store-operated Ca2+ influx by B cell receptor cross-linking
JOURNAL OF IMMUNOLOGY
A filarial nematode-secreted phosphorylcholine-containing glycoprotein uncouples the B cell antigen receptor from extracellular signal-regulated kinase-mitogen-activated protein kinase by promoting the surface Ig-mediated recruitment of Src homology 2 domain-containing tyrosine phosphatase-1 and Pac-1 mitogen-activated kinase-phosphatase
JOURNAL OF IMMUNOLOGY
Lyn is essential for Fc gamma receptor III-mediated systemic anaphylaxis but not for the Arthus reaction
JOURNAL OF EXPERIMENTAL MEDICINE
CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1
JOURNAL OF BIOLOGICAL CHEMISTRY
Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Functional analysis of Csk and CHK kinases in breast cancer cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Role of a JAK3-dependent biochemical signaling pathway in platelet activation and aggregation
JOURNAL OF BIOLOGICAL CHEMISTRY
CD45 negatively regulates monocytic cell differentiation by inhibiting phorbol 12-myristate 13-acetate-dependent activation and tyrosine phosphorylation of protein kinase C delta
JOURNAL OF BIOLOGICAL CHEMISTRY
Detergent-resistant membrane domains are required for mast cell activationbut dispensable for tyrosine phosphorylation upon aggregation of the high affinity receptor for IgE
JOURNAL OF BIOCHEMISTRY
Nitrotyrosine mimics phosphotyrosine binding to the SH2 domain of the src family tyrosine kinase lyn
FEBS LETTERS
B cell receptor signaling involves physical and functional association of FAK with Lyn and IgM
FEBS LETTERS
The clustered Fc gamma receptor II is recruited to Lyn-containing membranedomains and undergoes phosphorylation in a cholesterol-dependent manner
EUROPEAN JOURNAL OF IMMUNOLOGY
Differential sensitivity to acute cholesterol lowering of activation mediated via the high-affinity IgE receptor and Thy-1 glycoprotein
EUROPEAN JOURNAL OF IMMUNOLOGY
Maturation of erythroid cells and erythroleukemia development are affectedby the kinase activity of Lyn
CANCER RESEARCH
Signaling pathways activated by daunorubicin
BLOOD
Erythropoietin-stimulated Raf-1 tyrosine phosphorylation is associated with the tyrosine kinase Lyn in J2E erythroleukemic cells
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Antibody regulation of B cell development
NATURE IMMUNOLOGY
Epitope mimics and determinant spreading: pathways to autoimmunity
CELLULAR AND MOLECULAR LIFE SCIENCES
CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification
IMMUNITY
Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cellsignalling
SEMINARS IN IMMUNOLOGY
The tyrosine kinases p53/56lyn and p72syk are differentially expressed at the protein level but not at the messenger RNA level in nonreleasing human basophils
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
A requirement for lipid rafts in B cell receptor induced Ca2+ flux
CURRENT BIOLOGY
Regulation of CD45-induced signaling by galectin-1 in Burkitt lymphoma B cells
GLYCOBIOLOGY
Regulation of mast cell signaling through high-affinity IgE receptor by CD45 protein tyrosine phosphatase
INTERNATIONAL IMMUNOLOGY
Involvement of Shc and Cbl-PI 3-kinase in Lyn-dependent proliferative signaling pathways for G-CSF
ONCOGENE
Role of the rasGAP-associated docking protein p62(dok) in negative regulation of B cell receptor-mediated signaling
GENES & DEVELOPMENT
Src kinase-mediated signaling in leukocytes
JOURNAL OF LEUKOCYTE BIOLOGY
Small molecule inhibitors of Src family kinases
DRUGS OF THE FUTURE
Characteristic expression of Hck in human B-cell precursors (vol 28, pg 55, 2000)
EXPERIMENTAL HEMATOLOGY
Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest
EXPERIMENTAL HEMATOLOGY
Globotriaosyl ceramide (CD77/Gb3) in the glycolipid-enriched membrane domain participates in B-cell receptor-mediated apoptosis by regulating Lyn kinase activity in human B cells
EXPERIMENTAL HEMATOLOGY
Characteristic expression of Hck in human B-cell precursors
EXPERIMENTAL HEMATOLOGY
The B-cell-specific src-family kinase Blk is dispensable for B-cell development and activation
MOLECULAR AND CELLULAR BIOLOGY
The C-terminus of NIPP1 (nuclear inhibitor of protein phosphatase-1) contains a novel binding site for protein phosphatase-1 that is controlled by tyrosine phosphorylation and RNA binding
BIOCHEMICAL JOURNAL
CD19 regulates intrinsic B lymphocyte signal transduction and activation through a novel mechanism of processive amplification
IMMUNOLOGIC RESEARCH
Analysis of galectin 1-mediated cell signaling by combined precipitation and electrophoresis techniques
ELECTROPHORESIS
Immunologically mediated signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human Fc epsilon R1 signaling pathway
IMMUNOPHARMACOLOGY
An unsolved problem of the clonal selection theory and the model of an oligomeric B-cell antigen receptor
IMMUNOLOGICAL REVIEWS
CD72, a negative regulator of B-cell responsiveness
IMMUNOLOGICAL REVIEWS
B-cell antigen receptor competence regulates B-lymphocyte selection and survival
IMMUNOLOGICAL REVIEWS
The role of Bruton's tyrosine kinase in B-cell development and function: agenetic perspective
IMMUNOLOGICAL REVIEWS
Signal transduction via the B-cell antigen receptor: The role of protein tyrosine kinases and protein tyrosine phosphatases
SIGNAL TRANSDUCTION AND THE COORDINATION OF B LYMPHOCYTE DEVELOPMENT AND FUNCTION I
The B-cell antigen receptor: Formation of signaling complexes and the function of adaptor proteins
SIGNAL TRANSDUCTION AND THE COORDINATION OF B LYMPHOCYTE DEVELOPMENT AND FUNCTION I
Receptor modulators of B-cell receptor signalling - CD19/CD22
SIGNAL TRANSDUCTION AND THE COORDINATION OF B LYMPHOCYTE DEVELOPMENT AND FUNCTION I
Tyrosine kinase activation in the decision between growth, differentiation, and death responses initiated from the B cell antigen receptor
ADVANCES IN IMMUNOLOGY, VOL 75
Interactions between AMPA receptors and intracellular proteins
NEUROPHARMACOLOGY
A sensitized genetic system for the analysis of murine B lymphocyte signaltransduction pathways dependent on Bruton's tyrosine kinase
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Dysregulated expression of the Cd22 gene as a result of a short interspersed nucleotide element insertion in Cd22(a) lupus-prone mice
JOURNAL OF IMMUNOLOGY
Quantitative genetic variation in CD19 expression correlates with autoimmunity
JOURNAL OF IMMUNOLOGY
CD72 negatively regulates signaling through the antigen receptor of B cells
JOURNAL OF IMMUNOLOGY
Akt-dependent cytokine production in mast cells
JOURNAL OF EXPERIMENTAL MEDICINE
The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells
JOURNAL OF EXPERIMENTAL MEDICINE
p53/56(lyn) antisense shifts the 1,25-dihydroxyvitamin D3-induced G1/S block in HL60 cells to S phase
JOURNAL OF CELLULAR PHYSIOLOGY
Interactions between Fc epsilon RI and lipid raft components are regulatedby the actin cytoskeleton
JOURNAL OF CELL SCIENCE
Interaction of folate receptor with signaling molecules lyn and G alpha(i-3) in detergent-resistant complexes from the ovary carcinoma cell line IGROV1
JOURNAL OF CELL SCIENCE
Observing Fc epsilon RI signaling from the inside of the mast cell membrane
JOURNAL OF CELL BIOLOGY
CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway
JOURNAL OF BIOLOGICAL CHEMISTRY
Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress
JOURNAL OF BIOLOGICAL CHEMISTRY
Distinctive functions of Syk N-terminal and C-terminal SH2 domains in the signaling cascade elicited by oxidative stress in B cells
JOURNAL OF BIOCHEMISTRY
Syk-deficient eosinophils show normal interleukin-5-mediated differentiation, maturation, and survival but no longer respond to Fc gamma R activation
BLOOD
Norcantharidin-induced post-G(2)/M apoptosis is dependent on wild-type p53gene
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
uvby photometry of the magnetic CP stars HD 36668, 36 Lyncis, HD 86592, and HR 8861
ASTRONOMY AND ASTROPHYSICS
The genes of systemic autoimmunity
PROCEEDINGS OF THE ASSOCIATION OF AMERICAN PHYSICIANS
CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation
IMMUNITY
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
IMMUNITY
Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop
IMMUNITY
Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors
IMMUNITY
The chosen few? Positive selection and the generation of naive B lymphocytes
IMMUNITY
Apoptosis in inflammatory diseases
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Protein tyrosine kinase p53/p56(lyn) forms complexes with gamma-tubulin inrat basophilic leukemia cells
INTERNATIONAL IMMUNOLOGY
Co-receptors on B lymphocytes
CURRENT OPINION IN IMMUNOLOGY
B cell development: signal transduction by antigen receptors and their surrogates
CURRENT OPINION IN IMMUNOLOGY
Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1
ONCOGENE
Association of src-kinase Lyn and non-src-kinase Syk with the granulocyte colony-stimulating factor receptor (G-CSFR) is not abrogated in neutrophilsfrom severe congenital neutropenia patients with point mutations in the G-CSFR mRNA
INTERNATIONAL JOURNAL OF HEMATOLOGY
CD19 is a central response regulator of B lymphocyte signaling thresholds governing autoimmunity
JOURNAL OF DERMATOLOGICAL SCIENCE
Metabolic oxidative stress activates signal transduction and gene expression during glucose deprivation in human tumor cells
FREE RADICAL BIOLOGY AND MEDICINE
Therapeutic targeting of Src-kinase Lyn in myeloid leukemic cell growth
LEUKEMIA