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A computational model of the 5-HT3 receptor extracellular domain: search for ligand binding sites
THEORETICAL CHEMISTRY ACCOUNTS
Characterisation of neuropeptide Y receptor subtypes by synthetic NPY analogues and by anti-receptor antibodies
MOLECULES
Src inhibitors: genomics to therapeutics
EXPERT OPINION ON INVESTIGATIONAL DRUGS
SH2 and SH3 domains as targets for anti-proliferative agents
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Thermodynamic aspects of hydrophobicity and biological QSAR
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
Crystal structure of a truncated form of porcine odorant-binding protein
PROTEINS-STRUCTURE FUNCTION AND GENETICS
Pharmacological characterization of STKR, an insect G protein-coupled receptor for tachykinin-like peptides
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin beta subunits
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Structural mimicry in G protein-coupled receptors: Implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors
MOLECULAR PHARMACOLOGY
Structural determinants of adenophostin A activity at inositol trisphosphate receptors
MOLECULAR PHARMACOLOGY
Dissection of the promoter region of the inositol 1,4,5-trisphosphate receptor gene, itr-1, in C-elegans: A molecular basis for cell-specific expression of IP3R isoforms
JOURNAL OF MOLECULAR BIOLOGY
Requirements of basic amino acid residues within the lectin-like domain ofLOX-1 for the binding of oxidized low-density lipoprotein
FEBS LETTERS
Peptide-derived antagonists of the urokinase receptor. Affinity maturationby combinatorial chemistry, identification of functional epitopes, and inhibitory effect on cancer cell intravasation
BIOCHEMISTRY
Mass spectrometric analysis of cyanogen bromide fragments of integral membrane proteins at the picomole level: Application to rhodopsin
ANALYTICAL BIOCHEMISTRY
Mini-review: Computational structure-based design of inhibitors that target protein surfaces
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
The urokinase plasminogen activator system as a novel target for tumour therapy
FIBRINOLYSIS & PROTEOLYSIS
Evolutionary relationships among proteins encoded by the regulator of complement activation gene cluster
MOLECULAR BIOLOGY AND EVOLUTION
5-HT6 receptors as emerging targets for drug discovery
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
Interaction between PAK and Nck: a template for Nck targets and role of PAK autophosphorylation
MOLECULAR AND CELLULAR BIOLOGY
Monoclonal antibodies identity residues 199-216 of the integrin alpha 2 vWFA domain as a functionally important region within alpha 2 beta 1
BIOCHEMICAL JOURNAL
Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
ENDOCRINE REVIEWS
The role of receptor structure in determining adenosine receptor activity
PHARMACOLOGY & THERAPEUTICS
Differential modulation of inositol 1,4,5-trisphosphate receptor type 1 and type 3 by ATP
CELL CALCIUM
An isoleucine-based allosteric switch controls affinity and shape shiftingin integrin CD11b A-domain
JOURNAL OF BIOLOGICAL CHEMISTRY
Factors determining the composition of inositol trisphosphate receptor hetero-oligomers expressed in COS cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Expression of full-length and truncated recombinant human brain type I inositol 1,4,5-trisphosphate receptors in mammalian and insect cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
MULTICLUSTAL: a systematic method for surveying Clustal W alignment parameters
BIOINFORMATICS
Molecular modelling of the 5-hydroxytryptamine receptors
RECEPTORS & CHANNELS
Molecular dynamics of NPYY1 receptor activation
BIOORGANIC & MEDICINAL CHEMISTRY
Use of phosphorofluoridate analogues of D-myo-inositol 1,4,5-trisphosphateto assess the involvement of ionic interactions in its recognition by the receptor and metabolising enzymes
CELLULAR SIGNALLING
Modelling G-protein-coupled receptors for drug design
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON BIOMEMBRANES
3D modeling, ligand binding and activation studies of the cloned mouse delta, mu and kappa opioid receptors
PROTEIN ENGINEERING
Interactive binding to the two principal ligand binding sites of human serum albumin: effect of the neutral-to-base transition
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
Expression of inositol trisphosphate receptors
CELL CALCIUM
Inositol 1,4,5-trisphosphate receptors are strongly expressed in the nervous system, pharynx, intestine, gonad and excretory cell of Caenorhabditis elegans and are encoded by a single gene (itr-1)
JOURNAL OF MOLECULAR BIOLOGY
Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC
JOURNAL OF MOLECULAR BIOLOGY
Possible role for ligand binding of histidine 81 in the second transmembrane domain of the rat prostaglandin F-2 alpha receptor
FEBS LETTERS
Adenosine A(2A) receptor interactions with receptors for other neurotransmitters and neuromodulators
EUROPEAN JOURNAL OF PHARMACOLOGY
Human formyl peptide receptor function - Role of conserved and nonconserved charged residues
EUROPEAN JOURNAL OF BIOCHEMISTRY
Functional role of Arg-Gly-Asp (RGD)-binding sites on beta(1) integrin in embryo implantation using mouse blastocysts and human decidua
BIOLOGY OF REPRODUCTION
Antibodies against the PH domain of phospholipase C-delta 1 inhibit Ins(1,4,5)P-3-mediated Ca2+ release from the endoplasmic reticulum
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Inositol trisphosphate receptors: Ca2+-modulated intracellular Ca2+ channels
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
THERMAL UNFOLDING OF SMALL PROTEINS WITH SH3 DOMAIN FOLDING PATTERN
Proteins
New insights into the molecular mechanisms of A(1) adenosine receptor action
DRUG DEVELOPMENT RESEARCH
PREDICTION OF PROTEIN HYDRATION SITES FROM SEQUENCE BY MODULAR NEURALNETWORKS
Protein engineering
MUSCLE-SPECIFIC MESSENGER-RNA ISOFORM ENCODES A PROTEIN COMPOSED MAINLY OF THE N-TERMINAL-175 RESIDUES OF TYPE-2 INS(1,4,5)P-3 RECEPTOR
Biochemical journal
INOSITOL TRISPHOSPHATE MEDIATES A RAS-INDEPENDENT RESPONSE TO LET-23 RECEPTOR TYROSINE KINASE ACTIVATION IN C-ELEGANS
Cell
SH3 IN MUSCLES - SOLUTION STRUCTURE OF THE SH3 DOMAIN FROM NEBULIN
Journal of Molecular Biology
PROBING OF THE NEUROPEPTIDE Y-Y-1-RECEPTORS INTERACTION WITH ANTIRECEPTOR ANTIBODIES
European journal of biochemistry
THE ACCESSIBLE SURFACE OF THE NICOTINIC ACETYLCHOLINE-RECEPTOR - IDENTIFICATION BY CHEMICAL MODIFICATION AND CROSS-LINKING WITH C-14-DIMETHYL SUBERIMIDATE
European journal of biochemistry
SOLUTION STRUCTURE OF THE SH3 DOMAIN FROM BRUTONS TYROSINE KINASE
Biochemistry
THE FOLDING KINETICS AND THERMODYNAMICS OF THE FYN-SH3 DOMAIN
Biochemistry
SUBSTANCE-P DERIVATIVES WITH PHOTOACTIVATABLE LABELS IN THE N-TERMINAL PART OF THE MOLECULE
The journal of peptide research
GETTING IT TOGETHER - SIGNAL-TRANSDUCTION IN G-PROTEIN COUPLED RECEPTORS BY ASSOCIATION OF RECEPTOR DOMAINS
Chemistry & biology
THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER
Nature structural biology
IDENTIFICATION OF CLASS-DETERMINING RESIDUES IN G-PROTEIN-COUPLED RECEPTORS BY SEQUENCE-ANALYSIS
Receptors & channels
THE INSP(3) RECEPTOR AND INTRACELLULAR CA2+ SIGNALING
Current opinion in neurobiology
INTEGRIN ALPHA(IIB)BETA(3) AND PLATELET-FUNCTION
Thrombosis and haemostasis
DIFFERENTIAL REGULATION OF TYPE-1 AND TYPE-3 INOSITOL TRISPHOSPHATE RECEPTORS BY CYTOSOLIC CA2+
Biochemical journal
BETA-ADRENOCEPTOR SUBTYPES AND THEIR DESENSITIZATION MECHANISMS
Journal of autonomic pharmacology
ANTAGONISTS OF THE TACHYKININ RECEPTORS
Bioorganiceskaa himia
THE ESTRADIOL PHARMACOPHORE - LIGAND STRUCTURE-ESTROGEN RECEPTOR-BINDING AFFINITY RELATIONSHIPS AND A MODEL FOR THE RECEPTOR-BINDING SITE
Steroids
GALANIN RECEPTORS - INVOLVEMENT IN FEEDING, PAIN, DEPRESSION AND ALZHEIMERS-DISEASE
Life sciences
SOLUTION STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A10-RESIDUE PEPTIDE DERIVED FROM SOS - DIRECT REFINEMENT AGAINST NOES,J-COUPLINGS AND H-1 AND C-13 CHEMICAL-SHIFTS
Journal of Molecular Biology
MUTAGENESIS REVEALS STRUCTURE-ACTIVITY PARALLELS BETWEEN HUMAN A(2A)-ADENOSINE RECEPTORS AND BIOGENIC-AMINE G-PROTEIN-COUPLED RECEPTORS
Journal of medicinal chemistry
MOLECULAR AND FUNCTIONAL EVIDENCE FOR MULTIPLE CA2-BINDING DOMAINS INTHE TYPE-1 INOSITOL 1,4,5,-TRISPHOSPHATE RECEPTOR()
The Journal of biological chemistry
A NOVEL PEPTIDE MOTIF FOR PLATELET FIBRINOGEN RECEPTOR RECOGNITION
The Journal of biological chemistry
FUNCTIONAL RELEVANCE DURING LYMPHOCYTE MIGRATION AND CELLULAR-LOCALIZATION OF ACTIVATED BETA-1 INTEGRINS
European Journal of Immunology
BONA-FIDE PREDICTIONS OF PROTEIN SECONDARY STRUCTURE USING TRANSPARENT ANALYSES OF MULTIPLE SEQUENCE ALIGNMENTS
Chemical reviews
RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS
Annual review of cell and developmental biology
STABILITY AND FOLDING OF THE SH3 DOMAIN OF BRUTONS TYROSINE KINASE
Proteins
RATIONAL DESIGN FOR THE DEVELOPMENT OF EPIDERMAL GROWTH-FACTOR RECEPTOR ANTAGONISTS
Pathology research and practice
A RAS-GTPASE-ACTIVATING PROTEIN SH3-DOMAIN-BINDING PROTEIN
Molecular and cellular biology
A 3D MODEL OF THE DELTA-OPIOID RECEPTOR AND LIGAND-RECEPTOR COMPLEXES
Protein engineering
NOE-DERIVED CONFORMATION OF GRGDSP CELL-ADHESION RECOGNITION SITE IN THE PRESENCE OF SDS MICELLES AND INTEGRIN RECEPTOR GPIIB IIIA/
Biochimica et biophysica acta. Protein structure and molecular enzymology
CHARACTERIZATION OF SITE-I ON HUMAN SERUM-ALBUMIN - CONCEPT ABOUT THESTRUCTURE OF A DRUG-BINDING SITE
Biochimica et biophysica acta. Protein structure and molecular enzymology
CRYSTAL-STRUCTURE OF P13K SH3 DOMAIN AT 2.0 ANGSTROM RESOLUTION
Journal of Molecular Biology
NMR ANALYSIS OF INTERACTING SOLUBLE FORMS OF THE CELL-CELL RECOGNITION MOLECULES CD2 AND CD48
Biochemistry
INTEGRIN RECEPTOR GPIIB IIIA BOUND-STATE CONFORMATION OF THE FIBRINOGEN GAMMA-CHAIN C-TERMINAL PEPTIDE-400-411 - NMR AND TRANSFER NOE STUDIES/
Biochemistry
INTEGRINS - EMERGING PARADIGMS OF SIGNAL-TRANSDUCTION
Annual review of cell and developmental biology
DYNAMIC REGULATION OF INTEGRINS
Stem cells
GABA(A) RECEPTOR SUBTYPES - WHICH, WHERE AND WHY
Seminars in the neurosciences
ADENOSINE RECEPTOR SUBTYPES - CHARACTERIZATION AND THERAPEUTIC REGULATION
Annual review of pharmacology and toxicology
PLATELET INTEGRINS
Thrombosis and haemostasis
CHARACTERIZATION OF FUS1 OF SCHIZOSACCHAROMYCES-POMBE - A DEVELOPMENTALLY CONTROLLED FUNCTION NEEDED FOR CONJUGATION
Molecular and cellular biology
PROTEIN 3-DIMENSIONAL STRUCTURE AND DRUG DESIGN - SOME EXAMPLES FROM INTRACELLULAR COMPONENTS OF THE SIGNAL-TRANSDUCTION PATHWAY
European journal of medicinal chemistry
ANTI-GPIIB IIIA ANTIBODIES - POWERFUL TOOLS TO INVESTIGATE FUNCTION AND REGULATION OF AN INTEGRIN/
Seminars in thrombosis and hemostasis
LIGHT-INDUCED AND THERMAL RELAXATION IN A PROTEIN
Physical review letters
ADENOSINE RECEPTORS
Neuropharmacology
MUSCARINIC ACETYLCHOLINE-RECEPTORS - STRUCTURAL BASIS OF LIGAND-BINDING AND G-PROTEIN COUPLING
Life sciences
THE CRYSTAL-STRUCTURE OF THE N-TERMINAL SH3 DOMAIN OF GRB2
Journal of Molecular Biology
A SINGLE AMINO-ACID EXCHANGE, ARG-45 TO ALA, GENERATES AN EPIDERMAL GROWTH-FACTOR (EGF) MUTANT WITH HIGH-AFFINITY FOR THE CHICKEN EGF RECEPTOR
The Journal of biological chemistry
CHARACTERIZATION OF THE MAMMALIAN YAP (YES-ASSOCIATED PROTEIN) GENE AND ITS ROLE IN DEFINING A NOVEL PROTEIN MODULE, THE WW DOMAIN
The Journal of biological chemistry
SEQUENCES AND STRUCTURES OF RETINAL PROTEINS
Israel Journal of Chemistry
THE IMPORTANCE OF 2 SPECIFIC DOMAINS IN LIGAND-BINDING TO THE AMPA KAINATE GLUTAMATE RECEPTORS GLUR2 AND GLURG/
FEBS letters
COMPLETE NUCLEOTIDE-SEQUENCE, EXPRESSION, AND CHROMOSOMAL LOCALIZATION OF HUMAN MIXED-LINEAGE KINASE-2
European journal of biochemistry
STRUCTURAL CHARACTERIZATION OF FOLDED AND UNFOLDED STATES OF AN SH3 DOMAIN IN EQUILIBRIUM IN AQUEOUS BUFFER
Biochemistry
ADENOSINE RECEPTORS - PROTEIN AND GENE STRUCTURE
Archives internationales de pharmacodynamie et de therapie
HIGH-RESOLUTION CRYSTAL-STRUCTURES OF TYROSINE KINASE SH3 DOMAINS COMPLEXED WITH PROLINE-RICH PEPTIDES
Nature structural biology
SIGNALING AN INTEREST
Nature structural biology