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    1. Weinreb, M; Machwate, M; Shir, N; Abramovitz, M; Rodan, GA; Harada, S
      Expression of the prostaglandin E-2 (PGE(2)) receptor subtype EP4 and its regulation by PGE(2) in osteoblastic cell lines and adult rat bone tissue

      BONE
    2. Simsir, A; Fetsch, P; Bedrossian, CWM; Ioffe, OB; Abati, A
      Absence of SV-40 large T antigen (Tag) in malignant mesothelioma effusions: An immunocytochemical study

      DIAGNOSTIC CYTOPATHOLOGY
    3. Corti, S; Salani, S; Del Bo, R; Torrente, Y; Strazzer, S; Belicchi, M; Paganoni, S; Li, Z; Comi, GP; Bresolin, N; Paulin, D; Scarlato, G
      T-antigen regulated expression reduces apoptosis of Tag-transformed human myoblasts

      CELLULAR AND MOLECULAR LIFE SCIENCES
    4. Tascou, S; Nayernia, K; Meinhardt, A; Schweyer, S; Engel, W; Trappe, R; Burfeind, P
      Targeted expression of SV40 large tumour antigen (TAg) induces a transientenhancement of spermatocyte proliferation and apoptosis

      MOLECULAR HUMAN REPRODUCTION
    5. Jasani, B; Jones, CJ; Radu, C; Wynford-Thomas, D; Navabi, H; Mason, M; Adams, M; Gibbs, A
      Simian virus 40 detection in human mesothelioma: Reliability and significance of the available molecular evidence

      FRONTIERS IN BIOSCIENCE
    6. Tlsty, TD; Romanov, SR; Kozakiewicz, BK; Holst, CR; Haupt, LM; Crawford, YPG
      Loss of chromosomal integrity in human mammary epithelial cells subsequentto escape from senescence

      JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    7. Abou Merhi, R; Guillaud, L; Delouis, C; Cotinot, C
      Establishment and characterization of immortalized ovine Sertoli cell lines

      IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
    8. Leung, EHL; Leung, PCK; Auersperg, N
      Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature-sensitive SV40 T antigen

      IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
    9. Rickert, CH; Paulus, W
      Tumors of the choroid plexus

      MICROSCOPY RESEARCH AND TECHNIQUE
    10. Strickler, HD; Goedert, JJ; Butel, JS; Daniel, R; Freymuth, F; Gibbs, A; Griffiths, DJ; Jablons, D; Jasani, B; Jones, C; Lednicky, JA; Miller, CW; Radu, C; Richards, WG; Shah, KV; You, L; Corson, JM; Gerwin, B; Harris, C; Sugarbaker, DJ; Egan, W; Lewis, AM; Krause, PR; Peden, K; Levine, AS; Melnick, S; Cosentino, M; da Costa, M; Devairrakam, V; Ji, J; Palefsky, J; Rasmussen, L; Shea, K; Wacholder, S; Waters, D; Wright, T
      A multicenter evaluation of assays for detection of SV40 DNA and results in masked mesothelioma specimens

      CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
    11. Chang, S; Khoo, C; DePinho, RA
      Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse

      SEMINARS IN CANCER BIOLOGY
    12. Pipas, JM; Levine, AJ
      Role of T antigen interactions with p53 in tumorigenesis

      SEMINARS IN CANCER BIOLOGY
    13. Testa, JR; Giordano, A
      SV40 and cell cycle perturbations in malignant mesothelioma

      SEMINARS IN CANCER BIOLOGY
    14. Lednicky, JA; Butel, JS
      Simian virus 40 regulatory region structural diversity and the associationof viral archetypal regulatory regions with human brain tumors

      SEMINARS IN CANCER BIOLOGY
    15. Jasani, B; Cristaudo, A; Emri, SA; Gazdar, AF; Gibbs, A; Krynska, B; Miller, C; Mutti, L; Radu, C; Tognon, M; Procopio, A
      Association of SV40 with human tumours

      SEMINARS IN CANCER BIOLOGY
    16. Schrump, DS; Waheed, I
      Strategies to circumvent SV40 oncoprotein expression in malignant pleural mesotheliomas

      SEMINARS IN CANCER BIOLOGY
    17. Egelkrout, EM; Robertson, D; Hanley-Bowdoin, L
      Proliferating cell nuclear antigen transcription is repressed through an E2F consensus element and activated by geminivirus infection in mature leaves

      PLANT CELL
    18. Klawitz, I; Preuss, U; Scheidtmann, KH
      Interaction of SV40 large T antigen with components of the nucleo/cytoskeleton

      INTERNATIONAL JOURNAL OF ONCOLOGY
    19. Deb, D; Lanyi, A; Scian, M; Keiger, J; Brown, DR; Le Roith, D; Deb, SP; Deb, S
      Differential modulation of cellular and viral promoters by p73 and p53

      INTERNATIONAL JOURNAL OF ONCOLOGY
    20. Park, SB; Standaert, RF
      A photoregulated ligand for the nuclear import receptor karyopherin alpha

      BIOORGANIC & MEDICINAL CHEMISTRY
    21. Kobayashi, N; Noguchi, H; Westerman, KA; Watanabe, T; Matsumura, T; Totsugawa, T; Fujiwara, T; Leboulch, P; Tanaka, N
      Successful retroviral gene transfer of simian virus 40 T antigen and herpes simplex virus-thymidine kinase into human hepatocytes

      CELL TRANSPLANTATION
    22. Kobayashi, N; Noguchi, H; Westerman, KA; Watanabe, T; Matsumura, T; Totsugawa, T; Fujiwara, T; Leboulch, P; Tanaka, N
      Cre/loxP-based reversible immortalization of human hepatocytes

      CELL TRANSPLANTATION
    23. McMurray, HR; Nguyen, D; Westbrook, TF; McCance, DJ
      Biology of human papillomaviruses

      INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
    24. Munger, K; Basile, JR; Duensing, S; Eichten, A; Gonzalez, SL; Grace, M; Zacny, VL
      Biological activities and molecular targets of the human papillomavirus E7oncoprotein

      ONCOGENE
    25. Saenz-Robles, MT; Sullivan, CS; Pipas, JM
      Transforming functions of Simian Virus 40

      ONCOGENE
    26. Imperiale, MJ
      Oncogenic transformation by the human polyomaviruses

      ONCOGENE
    27. Deneen, B; Denny, CT
      Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation

      ONCOGENE
    28. Jiang, M; Axe, T; Holgate, R; Rubbi, CP; Okorokov, AL; Mee, T; Milner, J
      p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress

      ONCOGENE
    29. Parreno, M; Garriga, J; Limon, A; Albrecht, JH; Grana, X
      E1A modulates phosphorylation of p130 and p107 by differentially regulating the activity of G1/S cyclin/CDK complexes

      ONCOGENE
    30. Weggen, S; Preuss, U; Pietsch, T; Hilger, N; Klawitz, I; Scheidtmann, KH; Wiestler, OD; Bayer, TA
      Identification of amplified genes from SV40 large T antigen-induced rat PNET cell lines by subtractive cDNA analysis and radiation hybrid mapping

      ONCOGENE
    31. Taylor, WR; Stark, GR
      Regulation of the G2/M transition by p53

      ONCOGENE
    32. Moens, U; Van Ghelue, M; Kristoffersen, AK; Johansen, B; Rekvig, OP; Degre, M; Rollag, H
      Simian virus 40 large T-antigen, but not small T-antigen, trans-activates the human cytomegalovirus major immediate early promoter

      VIRUS GENES
    33. Terasaki, T; Hosoya, K
      Conditionally immortalized cell lines as a new in vitro model for the study of barrier functions

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    34. Seebach, JD; Schneider, MKJ; Comrack, CA; LeGuern, A; Kolb, SA; Knolle, PA; Germana, S; DerSimonian, H; LeGuern, C; Sachs, DH
      Immortalized bone-marrow derived pig endothelial cells

      XENOTRANSPLANTATION
    35. Hatakeyama, S; Ohara-Nemoto, Y; Yanai, N; Obinata, M; Hayashi, S; Satoh, M
      Establishment of gingival epithelial cell lines from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene

      JOURNAL OF ORAL PATHOLOGY & MEDICINE
    36. Yeh, CC; Lee, C; Huang, MC; Dahiya, R
      Loss of mismatch repair activity in simian virus 40 large T antigen-immortaIized BPH-1 human prostatic epithelial cell line

      MOLECULAR CARCINOGENESIS
    37. Derer, W; Easwaran, HP; Leonhardt, H; Cardoso, MC
      A novel approach to induce cell cycle reentry in terminally differentiatedmuscle cells

      FASEB JOURNAL
    38. Hanover, JA
      Glycan-dependent signaling: O-linked N-acetylglucosamine

      FASEB JOURNAL
    39. Andley, UP; Song, Z; Wawrousek, EF; Brady, JP; Bassnett, S; Fleming, TP
      Lens epithelial cells derived from alpha B-crystallin knockout mice demonstrate hyperproliferation and genomic instability

      FASEB JOURNAL
    40. Haynes, RL; Brune, B; Townsend, AJ
      Apoptosis in raw 264.7 cells exposed to 4-hydroxy-2-nonenal: Dependence oncytochrome c release but not p53 accumulation

      FREE RADICAL BIOLOGY AND MEDICINE
    41. Choi, SJ; Han, JH; Roodman, GD
      ADAM8: A novel osteoclast stimulating factor

      JOURNAL OF BONE AND MINERAL RESEARCH
    42. Kim, BH; Sung, SR; Park, JK; Kim, YI; Kim, KJ; Dong, SH; Kim, HJ; Chang, YW; Lee, JI; Chang, R
      Survival of conditionally immortalized hepatocytes in the spleen of syngeneic rats

      JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
    43. Gurney, JG; Smith, MA; Olshan, AF; Hecht, SS; Kasum, CM
      Clues to the etiology of childhood brain cancer: N-nitroso compounds, polyomaviruses, and other factors of interest

      CANCER INVESTIGATION
    44. Kitaoka, E; Satomura, K; Hayashi, E; Yamanouchi, K; Tobiume, S; Kume, K; Obinata, M; Nagayama, M
      Establishment and characterization of chondrocyte cell lines from the costal cartilage of SV40 large T antigen transgenic mice

      JOURNAL OF CELLULAR BIOCHEMISTRY
    45. Hattori, K; Muta, M; Toi, M; Iizasa, H; Shinsei, M; Terasaki, T; Obinata, M; Ueda, M; Nakashima, E
      Establishment of bone marrow-derived endothelial cell lines from ts-SV40 T-antigen gene transgenic rats

      PHARMACEUTICAL RESEARCH
    46. van Leeuwen, EBM; Wisman, GBA; Tervaert, JWC; Palmans, LL; van Wijk, RT; Veenstra, R; Molema, G; van der Zee, AGJ; van der Meer, J; Ruiters, MHJ
      An SV40 large T-antigen immortalized human umbilical vein endothelial cellline for anti-endothelial cell antibody detection

      CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
    47. Zhen, HN; Zhang, X; Zhang, ZW; Fei, Z; He, XS; Liang, JW; Huang, WJ; Liu, XZ; Zhang, P
      Simian virus 40 large tumor antigen forms specific complexes with p53 and pRb in human brain tumors

      CHINESE MEDICAL JOURNAL
    48. Takacs-Jarrett, M; Sweeney, WE; Avner, ED; Cotton, CU
      Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2K(b)-tsA58 transgene

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    49. Li, TK; Liu, LF
      Tumor cell death induced by topoisomerase-targeting drugs

      ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY
    50. Yuan, RQ; Meng, QH; Hu, H; Goldberg, ID; Rosen, EM; Fan, SJ
      P53-independent downregulation of p73 in human cancer cells treated with Adriamycin

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    51. Adams, PD
      Regulation of the retinoblastoma tumor suppressor protein by cyclin/cdks

      BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
    52. David, H; Mendoza, S; Konishi, T; Miller, CW
      Simian virus 40 is present in human lymphomas and normal blood

      CANCER LETTERS
    53. Batchu, RB; Shammas, MA; Wang, JY; Reis, RJS; Munshi, NC
      Expression of AAV Rep proteins in SV40-transformed and untransformed cells: Reciprocal interaction with host DNA synthesis

      INTERVIROLOGY
    54. Chen, KH; Azar, D; Joyce, NC
      Transplantation of adult human corneal endothelium ex vivo - A morphologicstudy

      CORNEA
    55. Dehde, S; Rohaly, G; Schub, O; Nasheuer, HP; Bohn, W; Chemnitz, J; Deppert, W; Dornreiter, I
      Two immunologically distinct human DNA polymerase alpha-primase subpopulations are involved in cellular DNA replication

      MOLECULAR AND CELLULAR BIOLOGY
    56. Collins, I; Weber, A; Levens, D
      Transcriptional consequences of topoisomerase inhibition

      MOLECULAR AND CELLULAR BIOLOGY
    57. Bird, CH; Blink, EJ; Hirst, CE; Buzza, MS; Steele, PM; Sun, JR; Jans, SA; Bird, PI
      Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1

      MOLECULAR AND CELLULAR BIOLOGY
    58. Xing, J; Sheppard, HM; Corneillie, SI; Liu, X
      P53 stimulates TFIID-TFIIA-promoter complex assembly, and p53-T antigen complex inhibits TATA binding protein-TATA interaction

      MOLECULAR AND CELLULAR BIOLOGY
    59. Briggs, LJ; Johnstone, RW; Elliot, RM; Xiao, CY; Dawson, M; Trapani, JA; Jans, DA
      Novel properties of the protein kinase CK2-site-regulated nuclear-localization sequence of the interferon-induced nuclear factor IFI 16

      BIOCHEMICAL JOURNAL
    60. Kim, HY; Ahn, BY; Cho, Y
      Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen

      EMBO JOURNAL
    61. Kolettas, E; Evangelou, A; Gonos, ES
      nu-FBR-fos oncogene fails to rescue mammalian cells from growth arrest butaffects the responses of human fibroblasts to heparin

      ANTICANCER RESEARCH
    62. Taylor, MD; Mainprize, TG; Squire, JA; Rutka, JT
      Molecular genetics of pineal region neoplasms

      JOURNAL OF NEURO-ONCOLOGY
    63. Sandberg, AA; Bridge, JA
      Updates on the cytogenetics and molecular genetics of bone and soft tissuetumors. Mesothelioma

      CANCER GENETICS AND CYTOGENETICS
    64. Kim, TY; Kim, WI; Smith, RE; Kay, EP
      Role of p27(Kip1) in cAMP- and TGF-beta 2-mediated antiproliferation in rabbit corneal endothelial cells

      INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
    65. Bullock, SK; Kaufmann, WK; Cordeiro-Stone, M
      Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant

      CARCINOGENESIS
    66. Nitta, M; Katabuchi, H; Ohtake, H; Tashiro, H; Yamaizumi, M; Okamura, H
      Characterization and tumorigenicity of human ovarian surface epithelial cells immortalized by SV40 large T antigen

      GYNECOLOGIC ONCOLOGY
    67. Hubner, S; Jans, DA; Drenckhahn, D
      Roles of cytoskeletal and junctional plaque proteins in nuclear signaling

      INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 208
    68. Champoux, JJ
      DNA topoisomerases: Structure, function, and mechanism

      ANNUAL REVIEW OF BIOCHEMISTRY
    69. Pourquier, P; Pommier, Y
      Topoisomerase I-mediated DNA damage

      ADVANCES IN CANCER RESEARCH, VOL 80
    70. Sullivan, CS; Pipas, JM
      The virus-chaperone connection

      VIROLOGY
    71. Kulaeva, OI; Lutter, LC
      TATA box occupancy in the SV40 transcription elongation complex

      VIROLOGY
    72. Yokoyama, A; Kawaguchi, Y; Kitabayashi, I; Ohki, M; Hirai, K
      The conserved domain CR2 of Epstein-Barr virus nuclear antigen leader protein is responsible not only for nuclear matrix association but also for nuclear localization

      VIROLOGY
    73. Sullivan, CS; Gilbert, SP; Pipas, JM
      ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation

      JOURNAL OF VIROLOGY
    74. West, M; Flanery, D; Woytek, K; Rangasamy, D; Wilson, VG
      Functional mapping of the DNA binding domain of bovine papillomavirus E1 protein

      JOURNAL OF VIROLOGY
    75. Chen, L; Fluck, M
      Kinetic analysis of the steps of the polyomavirus lytic cycle

      JOURNAL OF VIROLOGY
    76. Gonzalez, SL; Stremlau, M; He, X; Basile, JR; Munger, K
      Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and isseparable from proteasomal degradation of E7

      JOURNAL OF VIROLOGY
    77. Purviance, JD; Prack, AE; Barbaro, B; Bullock, PA
      In the simian virus 40 in vitro replication system, start site selection by the polymerase alpha-primase complex is not significantly altered by changes in the concentration of ribonucleotides

      JOURNAL OF VIROLOGY
    78. Reuther, FJ; Lohler, J; Herms, J; Hugo, HH; Schindler, C; Leithauser, F; Melzner, I; Moller, P; Scheil, S
      Low incidence of SV40-like sequences in ependymal tumours

      JOURNAL OF PATHOLOGY
    79. Kouhata, T; Fukuyama, K; Hagihara, N; Tabuchi, K
      Detection of simian virus 40 DNA sequence in human primary glioblastomas multiforme

      JOURNAL OF NEUROSURGERY
    80. Haidweger, E; Novy, M; Rotheneder, H
      Modulation of Sp1 activity by a cyclin A/CDK complex

      JOURNAL OF MOLECULAR BIOLOGY
    81. Tognon, M; Martini, F; Iaccheri, L; Cultrera, R; Contini, C
      Investigation of the simian polyomavirus SV40 as a potential causative agent of human neurological disorders in AIDS patients

      JOURNAL OF MEDICAL MICROBIOLOGY
    82. Johne, R; Muller, H
      Avian polyomavirus agnoprotein 1a is incorporated into the virus particle as a fourth structural protein, VP4

      JOURNAL OF GENERAL VIROLOGY
    83. Wassarman, DA; Sauer, F
      TAF(II)250: a transcription toolbox

      JOURNAL OF CELL SCIENCE
    84. Grammatikakis, N; Jaronczyk, K; Siganou, A; Vultur, A; Brownell, HL; Benzaquen, M; Rausch, C; Lapointe, R; Gjoerup, O; Roberts, TM; Raptis, L
      Simian virus 40 large tumor antigen modulates the Raf signaling pathway

      JOURNAL OF BIOLOGICAL CHEMISTRY
    85. White, PW; Pelletier, A; Brault, K; Titolo, S; Welchner, E; Thauvette, L; Fazekas, M; Cordingley, MG; Archambault, J
      Characterization of recombinant HPV6 and 11 E1 helicases - Effect of ATP on the interaction of E1 with E2 and mapping of a minimal helicase domain

      JOURNAL OF BIOLOGICAL CHEMISTRY
    86. Hodel, MR; Corbett, AH; Hodel, AE
      Dissection of a nuclear localization signal

      JOURNAL OF BIOLOGICAL CHEMISTRY
    87. Trentin, GA; Yin, XH; Tahir, S; Lhotak, S; Farhang-Fallah, J; Li, Y; Rozakis-Adcock, M
      A mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel pas GTPase-activating protein (RasGAP)-binding protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    88. Gu, XS; Shin, BH; Akbarali, Y; Weiss, A; Boltax, J; Oettgen, P; Libermann, TA
      Tel-2 is a novel transcriptional repressor related to the Ets factor Tel/ETV-6

      JOURNAL OF BIOLOGICAL CHEMISTRY
    89. Tabuchi, Y
      Characterization and application of a gastric surface mucous cell line GSM06 established from temperature-sensitive simian virus 40 large T-antigen transgenic mice

      JAPANESE JOURNAL OF PHARMACOLOGY
    90. Ehrlich, ME; Conti, L; Toselli, M; Taglietti, L; Fiorillo, E; Taglietti, V; Ivkovic, S; Guinea, B; Tranberg, A; Sipione, S; Rigamonti, D; Cattaneo, E
      ST14A cells have properties of a medium-size spiny neuron

      EXPERIMENTAL NEUROLOGY
    91. Hosoya, K; Tomi, M; Ohtsuki, S; Takanaga, H; Ueda, M; Yanai, N; Obinata, M; Terasaki, T
      Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat

      EXPERIMENTAL EYE RESEARCH
    92. Tedesco, D; Vesco, C
      MyoD activity upregulates E2F1 and enhances transcription from the cyclin E promoter in differentiating myoblasts lacking a functional retinoblastomaprotein

      EXPERIMENTAL CELL RESEARCH
    93. Harms, W; Rothamel, T; Miller, K; Harste, G; Grassman, M; Heim, A
      Characterization of human myocardial fibroblasts immortalized by HPV16 E6-E7 genes

      EXPERIMENTAL CELL RESEARCH
    94. Yang, Y; Sowden, MP; Yang, Y; Smith, HC
      Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein B mRNA

      EXPERIMENTAL CELL RESEARCH
    95. Classon, M; Dyson, N
      p107 and p130: Versatile proteins with interesting pockets

      EXPERIMENTAL CELL RESEARCH
    96. Brunskill, EW; Witte, DP; Yutzey, KE; Potter, SS
      Novel cell lines promote the discovery of genes involved in early heart development

      DEVELOPMENTAL BIOLOGY
    97. Green, JE; Shibata, MA; Shibata, E; Moon, RC; Anver, MR; Kelloff, G; Lubet, R
      2-difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumorprogression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice

      CANCER RESEARCH
    98. Paggi, MG; Giordano, A
      Who is the boss in the Retinoblastoma family? The point of view of Rb2/p130, the little brother

      CANCER RESEARCH
    99. Shridhar, V; Bible, KC; Staub, J; Avula, R; Lee, YK; Kalli, K; Huang, HJ; Hartmann, LC; Kaufmann, SH; Smith, DI
      Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer

      CANCER RESEARCH
    100. Powers, A; Rizzo, P; Di Resta, I; Matker, C; Kast, WM; Mutti, L; Pass, HI; Carbone, M
      Simian virus 40, asbestos, and the development of malignant mesotheliomas

      CANADIAN MINERALOGIST


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Documento generato il 21/10/20 alle ore 19:27:24