Le informazioni sugli articoli di fonte ISI sono coperte da copyright

Per ulteriori informazioni selezionare i riferimenti di interesse.

1. Thomas, T; Thomas, TJ
   Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications
   CELLULAR AND MOLECULAR LIFE SCIENCES
   
   T. Thomas e T.J. Thomas, "Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications", CELL MOL L, 58(2), 2001, pp. 244-258
2. Kartalou, M; Essigmann, JM
   Mechanisms of resistance to cisplatin
   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
   
   M. Kartalou e J.M. Essigmann, "Mechanisms of resistance to cisplatin", MUT RES-F M, 478(1-2), 2001, pp. 23-43
3. Kilpelainen, PT; Saarimies, J; Kontusaari, SI; Jarvinen, MJ; Soler, AP; Kallioinen, MJ; Hietala, OA
   Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility
   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
   
   P.T. Kilpelainen et al., "Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility", INT J BIO C, 33(5), 2001, pp. 507-520
4. Khokhar, NZ; She, Y; Rusch, VW; Sirotnak, FM
   Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: Further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums
   CLINICAL CANCER RESEARCH
   
   N.Z. Khokhar et al., "Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: Further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums", CLIN CANC R, 7(10), 2001, pp. 3199-3205
5. Perchellet, EM; Sperfslage, BJ; Qabaja, G; Jones, GA; Perchellet, JP
   Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cellsmore effectively than ellagic acid and genistein in vitro
   ANTI-CANCER DRUGS
   
   E.M. Perchellet et al., "Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cellsmore effectively than ellagic acid and genistein in vitro", ANTI-CANC D, 12(5), 2001, pp. 401-417
6. Barancik, M; Bohacova, V; Kvackajova, J; Hudecova, S; Krizanova, O; Breier, A
   SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance
   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
   
   M. Barancik et al., "SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance", EUR J PH SC, 14(1), 2001, pp. 29-36
7. Wareski, P; Motyl, T; Ryniewicz, Z; Orzechowski, A; Gajkowska, B; Wojewodzka, U; Ploszaj, T
   Expression of apoptosis-related proteins in mammary gland of goat
   SMALL RUMINANT RESEARCH
   
   P. Wareski et al., "Expression of apoptosis-related proteins in mammary gland of goat", SMALL RUMIN, 40(3), 2001, pp. 279-289
8. Bettuzzi, S; Strocchi, P; Davalli, P; Marinelli, M; Furci, L; Corti, A
   Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse
   BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
   
   S. Bettuzzi et al., "Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse", BIOC CELL B, 79(2), 2001, pp. 133-140
9. Zhu, WY; Alliegro, MA; Melera, PW
   The rate of folate receptor alpha (FR alpha) synthesis in folate depleted CHL cells is regulated by a translational mechanism sensitive to media folate levels, while stable overexpression of its mRNA is mediated by gene amplification and an increase in transcript half-life
   JOURNAL OF CELLULAR BIOCHEMISTRY
   
   W.Y. Zhu et al., "The rate of folate receptor alpha (FR alpha) synthesis in folate depleted CHL cells is regulated by a translational mechanism sensitive to media folate levels, while stable overexpression of its mRNA is mediated by gene amplification and an increase in transcript half-life", J CELL BIOC, 81(2), 2001, pp. 205-219
10. Rajgopal, A; Sierra, EE; Zhao, RB; Goldman, ID
    Expression of the reduced folate carrier SLC19A1 in IEC-6 cells results intwo distinct transport activities
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    
    A. Rajgopal et al., "Expression of the reduced folate carrier SLC19A1 in IEC-6 cells results intwo distinct transport activities", AM J P-CELL, 281(5), 2001, pp. C1579-C1586
11. de Nonancourt-Didion, M; Gueant, JL; Adjalla, C; Chery, C; Hatier, R; Namour, F
    Overexpression of folate binding protein alpha is one of the mechanism explaining the adaptation of HT29 cells to high concentration of methotrexate
    CANCER LETTERS
    
    M. de Nonancourt-Didion et al., "Overexpression of folate binding protein alpha is one of the mechanism explaining the adaptation of HT29 cells to high concentration of methotrexate", CANCER LETT, 171(2), 2001, pp. 139-145
12. Ikeda, K; Miura, K; Himeno, S; Imura, N; Naganuma, A
    Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum
    MOLECULAR AND CELLULAR BIOCHEMISTRY
    
    K. Ikeda et al., "Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum", MOL C BIOCH, 219(1-2), 2001, pp. 51-56
13. Shantz, LM; Feith, DJ; Pegg, AE
    Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy
    BIOCHEMICAL JOURNAL
    
    L.M. Shantz et al., "Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy", BIOCHEM J, 358, 2001, pp. 25-32
14. Stefanelli, C; Pignatti, C; Tantini, B; Fattori, M; Stanic, I; Mackintosh, CA; Flamigni, F; Guarnieri, C; Caldarera, CM; Pegg, AE
    Effect of polyamine depletion on caspase activation: a study with sperminesynthase-deficient cells
    BIOCHEMICAL JOURNAL
    
    C. Stefanelli et al., "Effect of polyamine depletion on caspase activation: a study with sperminesynthase-deficient cells", BIOCHEM J, 355, 2001, pp. 199-206
15. Hall, JG; Cory, AH; Hickerson, DHM; Cory, JG
    Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells
    ANTICANCER RESEARCH
    
    J.G. Hall et al., "Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells", ANTICANC R, 21(1A), 2001, pp. 173-180
16. Yuan, Q; Ray, RM; Viar, MJ; Johnson, LR
    Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    
    Q. Yuan et al., "Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells", AM J P-GAST, 280(1), 2001, pp. G130-G138
17. Matherly, LH
    Molecular and cellular biology of the human reduced folate carrier
    PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 67
    
    L.H. Matherly, "Molecular and cellular biology of the human reduced folate carrier", PROG NUCL A, 67, 2001, pp. 131-162
18. Mizutani, Y; Nakao, M; Ogawa, O; Yoshida, O; Bonavida, B; Miki, T
    Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin
    JOURNAL OF UROLOGY
    
    Y. Mizutani et al., "Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin", J UROL, 165(1), 2001, pp. 263-270
19. Valasinas, A; Sarkar, A; Reddy, VK; Marton, LJ; Basu, HS; Frydman, B
    Conformationally restricted analogues of N-1,N-14-bisethylhomospermine (BE-4-4-4): Synthesis and growth inhibitory effects on human prostate cancer cells
    JOURNAL OF MEDICINAL CHEMISTRY
    
    A. Valasinas et al., "Conformationally restricted analogues of N-1,N-14-bisethylhomospermine (BE-4-4-4): Synthesis and growth inhibitory effects on human prostate cancer cells", J MED CHEM, 44(3), 2001, pp. 390-403
20. Burns, MR; Carlson, CL; Vanderwerf, SM; Ziemer, JR; Weeks, RS; Cai, F; Webb, HK; Graminski, GF
    Amino acid/spermine conjugates: Polyamine amides as potent spermidine uptake inhibitors
    JOURNAL OF MEDICINAL CHEMISTRY
    
    M.R. Burns et al., "Amino acid/spermine conjugates: Polyamine amides as potent spermidine uptake inhibitors", J MED CHEM, 44(22), 2001, pp. 3632-3644
21. Martin, B; Posseme, F; Le Barbier, C; Carreaux, F; Carboni, B; Seiler, N; Moulinoux, JP; Delcros, JG
    N-benzylpolyamines as vectors of boron and fluorine for cancer therapy andimaging: Synthesis and biological evaluation
    JOURNAL OF MEDICINAL CHEMISTRY
    
    B. Martin et al., "N-benzylpolyamines as vectors of boron and fluorine for cancer therapy andimaging: Synthesis and biological evaluation", J MED CHEM, 44(22), 2001, pp. 3653-3664
22. Bergeron, RJ; Muller, R; Huang, GF; McManis, JS; Algee, SE; Yao, H; Weimar, WR; Wiegand, J
    Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives
    JOURNAL OF MEDICINAL CHEMISTRY
    
    R.J. Bergeron et al., "Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives", J MED CHEM, 44(15), 2001, pp. 2451-2459
23. Zhao, RB; Gao, F; Wang, YH; Diaz, GA; Gelb, BD; Goldman, ID
    Impact of the reduced folate carrier on the accumulation of active thiaminmetabolites in murine leukemia cells
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    R.B. Zhao et al., "Impact of the reduced folate carrier on the accumulation of active thiaminmetabolites in murine leukemia cells", J BIOL CHEM, 276(2), 2001, pp. 1114-1118
24. Zhao, RB; Russell, RG; Wang, YH; Liu, LB; Gao, F; Kneitz, B; Edelmann, W; Goldman, ID
    Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    R.B. Zhao et al., "Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs", J BIOL CHEM, 276(13), 2001, pp. 10224-10228
25. Cowan, DSM; Tannock, IF
    Factors that influence the penetration of methotrexate through solid tissue
    INTERNATIONAL JOURNAL OF CANCER
    
    D.S.M. Cowan e I.F. Tannock, "Factors that influence the penetration of methotrexate through solid tissue", INT J CANC, 91(1), 2001, pp. 120-125
26. Trippett, TM; Garcia, S; Manova, K; Mody, R; Cohen-Gould, L; Flintoff, W; Bertino, JR
    Localization of a human reduced folate carrier protein in the mitochondrial as well as the cell membrane of leukemia cells
    CANCER RESEARCH
    
    T.M. Trippett et al., "Localization of a human reduced folate carrier protein in the mitochondrial as well as the cell membrane of leukemia cells", CANCER RES, 61(5), 2001, pp. 1941-1947
27. Candra, E; Matsunaga, K; Fujiwara, H; Mimaki, Y; Sashida, Y; Yamakuni, T; Ohizumi, Y
    Two steroidal saponins from Camassia cusickii induce L1210 cell death through the apoptotic mechanism
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
    
    E. Candra et al., "Two steroidal saponins from Camassia cusickii induce L1210 cell death through the apoptotic mechanism", CAN J PHYSL, 79(11), 2001, pp. 953-958
28. Zhao, RB; Gao, F; Goldman, ID
    Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cells
    BIOCHEMICAL PHARMACOLOGY
    
    R.B. Zhao et al., "Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cells", BIOCH PHARM, 61(7), 2001, pp. 857-865
29. Wang, YH; Zhao, RB; Russell, RG; Goldman, ID
    Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
    
    Y.H. Wang et al., "Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis", BBA-BIOMEMB, 1513(1), 2001, pp. 49-54
30. Lee, SY; Park, HS; Lee, SJ; Choi, MU
    Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: Lack of selective activation of phospholipase A(2) by melittin
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    
    S.Y. Lee et al., "Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: Lack of selective activation of phospholipase A(2) by melittin", ARCH BIOCH, 389(1), 2001, pp. 57-67
31. Yarlett, N; Martinez, MP; Goldberg, B; Kramer, DL; Porter, CW
    Dependence of Trichomonas vaginalis upon polyamine backconversion
    MICROBIOLOGY-UK
    
    N. Yarlett et al., "Dependence of Trichomonas vaginalis upon polyamine backconversion", MICROBIO-UK, 146, 2000, pp. 2715-2722
32. Zhao, RB; Babani, S; Gao, F; Liu, LB; Goldman, ID
    The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate
    CLINICAL CANCER RESEARCH
    
    R.B. Zhao et al., "The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate", CLIN CANC R, 6(9), 2000, pp. 3687-3695
33. Sirotnak, FM; Wendel, HG; Bornmann, WGB; Tong, WP; Miller, VA; Scher, HI; Kris, MG
    Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo
    CLINICAL CANCER RESEARCH
    
    F.M. Sirotnak et al., "Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo", CLIN CANC R, 6(9), 2000, pp. 3705-3712
34. Somerville, L; Cory, JG
    Altered sensitivity of deoxyadenosine-resistant mouse leukemia L1210 cellsto apoptosis induced by 7-hydroxystaurosporine
    INTERNATIONAL JOURNAL OF ONCOLOGY
    
    L. Somerville e J.G. Cory, "Altered sensitivity of deoxyadenosine-resistant mouse leukemia L1210 cellsto apoptosis induced by 7-hydroxystaurosporine", INT J ONCOL, 17(4), 2000, pp. 797-803
35. Oldham, TC; Phillips, D
    Triplet-state photophysics of aluminium phthalocyanine sensitizer in murine cancer cells
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
    
    T.C. Oldham e D. Phillips, "Triplet-state photophysics of aluminium phthalocyanine sensitizer in murine cancer cells", J PHOTOCH B, 55(1), 2000, pp. 16-19
36. Rajski, SR; Williams, RM
    Observations on the covalent cross-linking of the binding domain (BD) of the High Mobility Group I/Y (HMG I/Y) proteins to DNA by FR66979
    BIOORGANIC & MEDICINAL CHEMISTRY
    
    S.R. Rajski e R.M. Williams, "Observations on the covalent cross-linking of the binding domain (BD) of the High Mobility Group I/Y (HMG I/Y) proteins to DNA by FR66979", BIO MED CH, 8(6), 2000, pp. 1331-1342
37. Ploszaj, T; Motyl, T; Zimowska, W; Skierski, J; Zwierzchowski, L
    Inhibition of ornithine decarboxylase by alpha-difluoromethylornithine induces apoptosis of HC11 mouse mammary epithelial cells
    AMINO ACIDS
    
    T. Ploszaj et al., "Inhibition of ornithine decarboxylase by alpha-difluoromethylornithine induces apoptosis of HC11 mouse mammary epithelial cells", AMINO ACIDS, 19(2), 2000, pp. 483-496
38. Farah, N; Dresner, HS; Searles, KJ; Winiarsky, R; Moosikasuwan, M; Cajigas, A; Hahm, S; Steinberg, JJ
    Cisplatin DNA adduct detection and depurination measured by P-32 DNA radiolabeling and two-dimensional thin-layer chromatography: A time and concentration study
    CANCER INVESTIGATION
    
    N. Farah et al., "Cisplatin DNA adduct detection and depurination measured by P-32 DNA radiolabeling and two-dimensional thin-layer chromatography: A time and concentration study", CANCER INV, 18(4), 2000, pp. 314-326
39. Tam, MN; Nam, NH; Jin, GZ; Song, GY; Ahn, BZ
    Synthesis and evaluation of the antitumor activity of 2-substituted 1,4-dihydroxy-9,10-anthraquinones
    ARCHIV DER PHARMAZIE
    
    M.N. Tam et al., "Synthesis and evaluation of the antitumor activity of 2-substituted 1,4-dihydroxy-9,10-anthraquinones", ARCH PHARM, 333(6), 2000, pp. 189-194
40. Ray, RM; Viar, MJ; Yuan, Q; Johnson, LR
    Polyamine depletion delays apoptosis of rat intestinal epithelial cells
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    
    R.M. Ray et al., "Polyamine depletion delays apoptosis of rat intestinal epithelial cells", AM J P-CELL, 278(3), 2000, pp. C480-C489
41. Honscha, W; Dotsch, KU; Thomsen, N; Petzinger, E
    Cloning and functional characterization of the bile acid-sensitive methotrexate carrier from rat liver cells
    HEPATOLOGY
    
    W. Honscha et al., "Cloning and functional characterization of the bile acid-sensitive methotrexate carrier from rat liver cells", HEPATOLOGY, 31(6), 2000, pp. 1296-1304
42. Cory, AH; Hickerson, DHM; Cory, JG
    Apoptosis induced by inhibitors of nucleotide synthesis in deoxyadenosine-resistant leukemia L1210 cells that lack p53 expression
    ANTICANCER RESEARCH
    
    A.H. Cory et al., "Apoptosis induced by inhibitors of nucleotide synthesis in deoxyadenosine-resistant leukemia L1210 cells that lack p53 expression", ANTICANC R, 20(6B), 2000, pp. 4171-4178
43. Karkabounas, S; Assimakopoulos, D; Malamas, M; Skaltsounis, AL; Leonce, S; Zelovitis, J; Stefanou, D; Evangelou, A
    Antiproliferative and anticarcinogenic effects of an aqueous preparation of Abies alba and Viscum album se abies, on a L-1210 malignant cell line andtumor-bearing Wistar rats
    ANTICANCER RESEARCH
    
    S. Karkabounas et al., "Antiproliferative and anticarcinogenic effects of an aqueous preparation of Abies alba and Viscum album se abies, on a L-1210 malignant cell line andtumor-bearing Wistar rats", ANTICANC R, 20(6B), 2000, pp. 4391-4395
44. Somerville, L; Cory, JG
    Enhanced roscovitine-induced apoptosis is mediated by a caspase-3-like activity in deoxyadenosine-resistant mouse leukemia L1210 cells
    ANTICANCER RESEARCH
    
    L. Somerville e J.G. Cory, "Enhanced roscovitine-induced apoptosis is mediated by a caspase-3-like activity in deoxyadenosine-resistant mouse leukemia L1210 cells", ANTICANC R, 20(5B), 2000, pp. 3347-3355
45. Rosowsky, A; Wright, JE; Vaidya, CM; Forsch, RA
    The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine
    PHARMACOLOGY & THERAPEUTICS
    
    A. Rosowsky et al., "The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine", PHARM THERA, 85(3), 2000, pp. 191-205
46. Khomutov, RM; Zhukov, YN; Khomutov, AR; Khurs, EN; Kramer, DL; Miller, JT; Porter, CW
    The inhibition of the L1210 cell growth by a phosphinic analogue of methionine and its transformation to the corresponding S-adenosylmethionine analogue
    BIOORGANICHESKAYA KHIMIYA
    
    R.M. Khomutov et al., "The inhibition of the L1210 cell growth by a phosphinic analogue of methionine and its transformation to the corresponding S-adenosylmethionine analogue", BIOORG KHIM, 26(9), 2000, pp. 718-720
47. Sharman, WM; Allen, CM; van Lier, JE
    Role of activated oxygen species in photodynamic therapy
    SINGLET OXYGEN, UV-A, AND OZONE
    
    W.M. Sharman et al., "Role of activated oxygen species in photodynamic therapy", METH ENZYM, 319, 2000, pp. 376-400
48. Williams, RM; Rollins, SB; Judd, TC
    Synthesis of the first photo-triggered pro-mitosene based on FR-900482
    TETRAHEDRON
    
    R.M. Williams et al., "Synthesis of the first photo-triggered pro-mitosene based on FR-900482", TETRAHEDRON, 56(4), 2000, pp. 521-532
49. Hoyt, MA; Williams-Abbott, LJ; Pitkin, JW; Davis, RH
    Cloning and expression of the S-adenosylmethionine decarboxylase gene of Neurospora crassa and processing of its product
    MOLECULAR AND GENERAL GENETICS
    
    M.A. Hoyt et al., "Cloning and expression of the S-adenosylmethionine decarboxylase gene of Neurospora crassa and processing of its product", MOL G GENET, 263(4), 2000, pp. 664-673
50. Bergeron, RJ; Muller, R; Bussenius, J; McManis, JS; Merriman, RL; Smith, RE; Yao, H; Weimar, WR
    Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives
    JOURNAL OF MEDICINAL CHEMISTRY
    
    R.J. Bergeron et al., "Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives", J MED CHEM, 43(2), 2000, pp. 224-235
51. Kuhnel, JM; Chiao, JH; Sirotnak, FM
    Contrasting effects of oncogene expression on two carrier-mediated systemsinternalizing folate compounds in fisher rat 3T3 cells
    JOURNAL OF CELLULAR PHYSIOLOGY
    
    J.M. Kuhnel et al., "Contrasting effects of oncogene expression on two carrier-mediated systemsinternalizing folate compounds in fisher rat 3T3 cells", J CELL PHYS, 184(3), 2000, pp. 364-372
52. Vujcic, S; Halmekyto, M; Diegelman, P; Gan, G; Kramer, DL; Janne, J; Porter, CW
    Effects of conditional overexpression of spermidine/spermine N-1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    S. Vujcic et al., "Effects of conditional overexpression of spermidine/spermine N-1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs", J BIOL CHEM, 275(49), 2000, pp. 38319-38328
53. Drori, S; Jansen, G; Mauritz, R; Peters, GJ; Assaraf, YG
    Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    S. Drori et al., "Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake", J BIOL CHEM, 275(40), 2000, pp. 30855-30863
54. McCloskey, DE; Pegg, AE
    Altered spermidine/spermine N-1-acetyltransferase activity as a mechanism of cellular resistance to bis(ethyl)polyamine analogues
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    D.E. McCloskey e A.E. Pegg, "Altered spermidine/spermine N-1-acetyltransferase activity as a mechanism of cellular resistance to bis(ethyl)polyamine analogues", J BIOL CHEM, 275(37), 2000, pp. 28708-28714
55. Bonneau, MJ; Poulin, R
    Spermine oxidation leads to necrosis with plasma membrane phosphatidylserine redistribution in mouse leukemia cells
    EXPERIMENTAL CELL RESEARCH
    
    M.J. Bonneau e R. Poulin, "Spermine oxidation leads to necrosis with plasma membrane phosphatidylserine redistribution in mouse leukemia cells", EXP CELL RE, 259(1), 2000, pp. 23-34
56. Belmokhtar, CA; Torriglia, A; Counis, MF; Courtois, Y; Jacquemin-Sablon, A; Segal-Bendirdjian, E
    Nuclear translocation of a leukocyte elastase inhibitor/elastase complex during staurosporine-induced apoptosis: Role in the generation of nuclear L-DNase II activity
    EXPERIMENTAL CELL RESEARCH
    
    C.A. Belmokhtar et al., "Nuclear translocation of a leukocyte elastase inhibitor/elastase complex during staurosporine-induced apoptosis: Role in the generation of nuclear L-DNase II activity", EXP CELL RE, 254(1), 2000, pp. 99-109
57. Drori, S; Sprecher, H; Shemer, G; Jansen, G; Goldman, ID; Assaraf, YG
    Characterization of a human alternatively spliced truncated reduced folatecarrier increasing folate accumulation in parental leukemia cells
    EUROPEAN JOURNAL OF BIOCHEMISTRY
    
    S. Drori et al., "Characterization of a human alternatively spliced truncated reduced folatecarrier increasing folate accumulation in parental leukemia cells", EUR J BIOCH, 267(3), 2000, pp. 690-702
58. Krejcova, R; Horska, K; Votruba, I; Holy, A
    Phosphorylation of purine (phosphonomethoxy)alkyl derivatives by mitochondrial AMP kinase (AK2 type) from L1210 cells
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
    
    R. Krejcova et al., "Phosphorylation of purine (phosphonomethoxy)alkyl derivatives by mitochondrial AMP kinase (AK2 type) from L1210 cells", COLL CZECH, 65(10), 2000, pp. 1653-1668
59. Bergeron, RJ; Merriman, RL; Olson, SG; Wiegand, J; Bender, J; Streiff, RR; Weimar, WR
    Metabolism and pharmacokinetics of N-1,N-11-diethylnorspermine in a Cebus apella primate model
    CANCER RESEARCH
    
    R.J. Bergeron et al., "Metabolism and pharmacokinetics of N-1,N-11-diethylnorspermine in a Cebus apella primate model", CANCER RES, 60(16), 2000, pp. 4433-4439
60. Volk, EL; Rohde, K; Rhee, M; McGuire, JJ; Doyle, LA; Ross, DD; Schneider, E
    Methotrexate cross-resistance in a mitoxantrone-selected multidrug-resistant MCF7 breast cancer cell line is attributable to enhanced energy-dependent drug efflux
    CANCER RESEARCH
    
    E.L. Volk et al., "Methotrexate cross-resistance in a mitoxantrone-selected multidrug-resistant MCF7 breast cancer cell line is attributable to enhanced energy-dependent drug efflux", CANCER RES, 60(13), 2000, pp. 3514-3521
61. Krejcova, R; Horska, K; Votruba, I; Holy, A
    Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenyzmes
    BIOCHEMICAL PHARMACOLOGY
    
    R. Krejcova et al., "Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenyzmes", BIOCH PHARM, 60(12), 2000, pp. 1907-1913
62. Wright, JE; Vaidya, CM; Chen, YN; Rosowsky, A
    Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine (PT523) and its B-ring analogues
    BIOCHEMICAL PHARMACOLOGY
    
    J.E. Wright et al., "Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine (PT523) and its B-ring analogues", BIOCH PHARM, 60(1), 2000, pp. 41-46
63. Finch, RA; Liu, MC; Grill, SP; Rose, WC; Loomis, R; Vasquez, KM; Cheng, YC; Sartorelli, AC
    Triapine (3-aminopyridine-2-carboxaldehydethiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity
    BIOCHEMICAL PHARMACOLOGY
    
    R.A. Finch et al., "Triapine (3-aminopyridine-2-carboxaldehydethiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity", BIOCH PHARM, 59(8), 2000, pp. 983-991
64. Brzezinska, A; Winska, P; Balinska, M
    Cellular aspects of folate and antifolate membrane transport
    ACTA BIOCHIMICA POLONICA
    
    A. Brzezinska et al., "Cellular aspects of folate and antifolate membrane transport", ACT BIOCH P, 47(3), 2000, pp. 735-749
65. Froelich, JJ; Schneller, FRG; Zahn, RK
    The influence of radiation and chemotherapy-related DNA strand breaks on carcinogenesis: An evaluation
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    
    J.J. Froelich et al., "The influence of radiation and chemotherapy-related DNA strand breaks on carcinogenesis: An evaluation", CLIN CH L M, 37(4), 1999, pp. 403-408
66. Sladek, NE
    Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines
    CURRENT PHARMACEUTICAL DESIGN
    
    N.E. Sladek, "Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines", CUR PHARM D, 5(8), 1999, pp. 607-625
67. Trippett, TM; Bertino, JR
    Therapeutic strategies targeting proteins that regulate folate and reducedfolate transport
    JOURNAL OF CHEMOTHERAPY
    
    T.M. Trippett e J.R. Bertino, "Therapeutic strategies targeting proteins that regulate folate and reducedfolate transport", J CHEMOTHER, 11(1), 1999, pp. 3-10
68. Olivares, E; Kadiata, MM; Malaisse, WJ
    Potentiation by 2-deoxy-D-glucose tetraacetate of the antitumoral action of 5-fluorouracil in mice inoculated with L1210 ascites-producing cells
    ONCOLOGY REPORTS
    
    E. Olivares et al., "Potentiation by 2-deoxy-D-glucose tetraacetate of the antitumoral action of 5-fluorouracil in mice inoculated with L1210 ascites-producing cells", ONCOL REP, 6(6), 1999, pp. 1309-1311
69. Crenshaw, TR; Cory, JG
    Mouse leukemia L1210 cells selected for resistance to the ribonucleotide reductase inhibitor, 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazoneshow altered response to DNA damaging agents
    INTERNATIONAL JOURNAL OF ONCOLOGY
    
    T.R. Crenshaw e J.G. Cory, "Mouse leukemia L1210 cells selected for resistance to the ribonucleotide reductase inhibitor, 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazoneshow altered response to DNA damaging agents", INT J ONCOL, 15(3), 1999, pp. 487-490
70. Perchellet, EM; Magill, MJ; Huang, XD; Brantis, CE; Hua, DH; Perchellet, JP
    Triptycenes: a novel synthetic class of bifunctional anticancer drugs thatinhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro
    ANTI-CANCER DRUGS
    
    E.M. Perchellet et al., "Triptycenes: a novel synthetic class of bifunctional anticancer drugs thatinhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro", ANTI-CANC D, 10(8), 1999, pp. 749-766
71. Stoika, RS; Yakymovych, MY; Yakymovych, IA; Chekhun, VF
    Cisplatin-resistant derivatives of murine L1210 leukemia cells are not susceptible to growth-inhibiting and apoptosis-inducing actions of transforming growth factor-beta 1
    ANTI-CANCER DRUGS
    
    R.S. Stoika et al., "Cisplatin-resistant derivatives of murine L1210 leukemia cells are not susceptible to growth-inhibiting and apoptosis-inducing actions of transforming growth factor-beta 1", ANTI-CANC D, 10(5), 1999, pp. 457-463
72. Minamino, T; Tamai, M; Itoh, Y; Tatsumi, Y; Nomura, M; Yokogawa, K; Suzuki, H; Sugiyama, Y; Ohshima, T; Miyamoto, K
    In vivo cisplatin resistance depending upon canalicular multispecific organic anion transporter (cMOAT)
    JAPANESE JOURNAL OF CANCER RESEARCH
    
    T. Minamino et al., "In vivo cisplatin resistance depending upon canalicular multispecific organic anion transporter (cMOAT)", JPN J CANC, 90(10), 1999, pp. 1171-1178
73. Gong, MK; Cowan, KH; Gudas, J; Moscow, JA
    Isolation and characterization of genomic sequences involved in the regulation of the human reduced folate carrier gene (RFC1)
    GENE
    
    M.K. Gong et al., "Isolation and characterization of genomic sequences involved in the regulation of the human reduced folate carrier gene (RFC1)", GENE, 233(1-2), 1999, pp. 21-31
74. Akiyama, S; Chen, ZS; Sumizawa, T; Furukawa, T
    Resistance to cisplatin
    ANTI-CANCER DRUG DESIGN
    
    S. Akiyama et al., "Resistance to cisplatin", ANTI-CAN DR, 14(2), 1999, pp. 143-151
75. Somerville, L; Cory, JG
    Altered sensitivity of deoxyadenosine-resistant mouse leukemia L1210 cellsto various kinase inhibitors
    ANTICANCER RESEARCH
    
    L. Somerville e J.G. Cory, "Altered sensitivity of deoxyadenosine-resistant mouse leukemia L1210 cellsto various kinase inhibitors", ANTICANC R, 19(2A), 1999, pp. 1021-1026
76. Yakymovych, MY; Yakymovych, IA; Tryndiak, VP; Stoika, RS
    Hyperthermia differentially induces apoptosis in murine L1210 leukemia cells sensitive and resistant to cisplatin
    EXPERIMENTAL ONCOLOGY
    
    M.Y. Yakymovych et al., "Hyperthermia differentially induces apoptosis in murine L1210 leukemia cells sensitive and resistant to cisplatin", EXP ONCOL, 21(2), 1999, pp. 154-156
77. Sirotnak, FM; Tolner, B
    Carrier-mediated membrane transport of folates in mammalian cells
    ANNUAL REVIEW OF NUTRITION
    
    F.M. Sirotnak e B. Tolner, "Carrier-mediated membrane transport of folates in mammalian cells", ANN R NUTR, 19, 1999, pp. 91-122
78. Bhushan, A; Hacker, MP; Tritton, TR
    Collateral methotrexate resistance in cisplatin-selected murine leukemia cells
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
    
    A. Bhushan et al., "Collateral methotrexate resistance in cisplatin-selected murine leukemia cells", BRAZ J MED, 32(7), 1999, pp. 827-833
79. Sierra, EE; Goldman, ID
    Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates
    SEMINARS IN ONCOLOGY
    
    E.E. Sierra e I.D. Goldman, "Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates", SEMIN ONCOL, 26(2), 1999, pp. 11-23
80. Honscha, V; Petzinger, E
    Characterization of the bile acid sensitive methotrexate carrier of rat liver cells
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    
    V. Honscha e E. Petzinger, "Characterization of the bile acid sensitive methotrexate carrier of rat liver cells", N-S ARCH PH, 359(5), 1999, pp. 411-419
81. Kool, M; van der Linden, M; de Haas, M; Scheffer, GL; de Vree, JML; Smith, AJ; Jansen, G; Peters, GJ; Ponne, N; Scheper, RJ; Elferink, RPJO; Baas, F; Borst, P
    MRP3, an organic anion transporter able to transport anti-cancer drugs
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    
    M. Kool et al., "MRP3, an organic anion transporter able to transport anti-cancer drugs", P NAS US, 96(12), 1999, pp. 6914-6919
82. Alhonen, L; Pietila, M; Halmekyto, M; Kramer, DL; Janne, J; Porter, CW
    Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N-1-acetyltransferase show enhanced sensitivity to the polyamine analog, N-1,N-11-diethylnorspermine
    MOLECULAR PHARMACOLOGY
    
    L. Alhonen et al., "Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N-1-acetyltransferase show enhanced sensitivity to the polyamine analog, N-1,N-11-diethylnorspermine", MOLEC PHARM, 55(4), 1999, pp. 693-698
83. Dobkowski, J; Kolos, R; Kaminski, J; Kowalczynska, HM
    Cell adhesion to polymeric surfaces: Experimental study and simple theoretical approach
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
    
    J. Dobkowski et al., "Cell adhesion to polymeric surfaces: Experimental study and simple theoretical approach", J BIOMED MR, 47(2), 1999, pp. 234-242
84. Wong, SC; Zhang, L; Witt, TL; Proefke, SA; Bhushan, A; Matherly, LH
    Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier
    JOURNAL OF BIOLOGICAL CHEMISTRY
    
    S.C. Wong et al., "Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier", J BIOL CHEM, 274(15), 1999, pp. 10388-10394
85. Petersen, G; Hansen, HS
    N-acylphosphatidylethanolamine-hydrolysing phospholipase D lacks the ability to transphosphatidylate
    FEBS LETTERS
    
    G. Petersen e H.S. Hansen, "N-acylphosphatidylethanolamine-hydrolysing phospholipase D lacks the ability to transphosphatidylate", FEBS LETTER, 455(1-2), 1999, pp. 41-44
86. Krejcova, R; Horska, K; Votruba, I; Holy, A
    Isoenzymes of GMP kinase from L1210 cells: Isolation and characterization
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
    
    R. Krejcova et al., "Isoenzymes of GMP kinase from L1210 cells: Isolation and characterization", COLL CZECH, 64(3), 1999, pp. 559-570
87. Jamieson, ER; Lippard, SJ
    Structure, recognition, and processing of cisplatin-DNA adducts
    CHEMICAL REVIEWS
    
    E.R. Jamieson e S.J. Lippard, "Structure, recognition, and processing of cisplatin-DNA adducts", CHEM REV, 99(9), 1999, pp. 2467-2498
88. Hooijberg, JH; Broxterman, HJ; Kool, M; Assaraf, YG; Peters, GJ; Noordhuis, P; Scheper, RJ; Borst, P; Pinedo, MM; Jansen, G
    Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2
    CANCER RESEARCH
    
    J.H. Hooijberg et al., "Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2", CANCER RES, 59(11), 1999, pp. 2532-2535
89. Assaraf, YG; Sierra, EE; Babani, S; Goldman, ID
    Inhibitory effects of prostaglandin A(1) on membrane transport of folates mediated by both the reduced folate carrier and ATP-driven exporters
    BIOCHEMICAL PHARMACOLOGY
    
    Y.G. Assaraf et al., "Inhibitory effects of prostaglandin A(1) on membrane transport of folates mediated by both the reduced folate carrier and ATP-driven exporters", BIOCH PHARM, 58(8), 1999, pp. 1321-1327
90. Zhao, RB; Gao, F; Goldman, ID
    Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier
    BIOCHEMICAL PHARMACOLOGY
    
    R.B. Zhao et al., "Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier", BIOCH PHARM, 58(10), 1999, pp. 1615-1624
91. Wang, ZJ; Fries, D; Blankenship, J
    Effect of N-8-acetylspermidine deacetylase inhibition on the growth of L1210 cells
    BIOCHEMICAL PHARMACOLOGY
    
    Z.J. Wang et al., "Effect of N-8-acetylspermidine deacetylase inhibition on the growth of L1210 cells", BIOCH PHARM, 57(10), 1999, pp. 1095-1103
92. Nakashima-Matsushita, N; Homma, T; Yu, S; Matsuda, T; Sunahara, N; Nakamura, T; Tsukano, M; Ratnam, M; Matsuyama, T
    Selective expression of folate receptor beta and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis
    ARTHRITIS AND RHEUMATISM
    
    N. Nakashima-Matsushita et al., "Selective expression of folate receptor beta and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis", ARTH RHEUM, 42(8), 1999, pp. 1609-1616
93. SEGALBENDIRDJIAN E; MANNONE L; JACQUEMINSABLON A
    ALTERATION IN P53 PATHWAY AND DEFECT IN APOPTOSIS CONTRIBUTE INDEPENDENTLY TO CISPLATIN-RESISTANCE
    Cell death and differentiation
    
    E. Segalbendirdjian et al., "ALTERATION IN P53 PATHWAY AND DEFECT IN APOPTOSIS CONTRIBUTE INDEPENDENTLY TO CISPLATIN-RESISTANCE", Cell death and differentiation, 5(5), 1998, pp. 390-400
94. ILGAN S; YANG DJ; HIGUCHI T; ZARENEYRIZI F; KIM EE; PODOLOFF DA
    IMAGING TUMOR FOLATE RECEPTORS USING (IN)-I-111-DTPA-METHOTREXATE
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
    
    S. Ilgan et al., "IMAGING TUMOR FOLATE RECEPTORS USING (IN)-I-111-DTPA-METHOTREXATE", CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 13(3), 1998, pp. 177-184
95. Ilgan, S; Yang, DJ; Higuchi, T; Zareneyrizi, F; Bayhan, H; Yu, DF; Kim, EE; Podoloff, DA
    Tc-99m-ethylenedicysteine-folate: A new tumor imaging agent. Synthesis, labeling and evaluation in animals
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
    
    S. Ilgan et al., "Tc-99m-ethylenedicysteine-folate: A new tumor imaging agent. Synthesis, labeling and evaluation in animals", CANC BIO R, 13(6), 1998, pp. 427-435
96. FINNELL RH; GREER KA; BARBER RC; PIEDRAHITA JA; SHAW GM; LAMMER EJ
    NEURAL-TUBE AND CRANIOFACIAL DEFECTS WITH SPECIAL EMPHASIS ON FOLATE PATHWAY GENES
    Critical reviews in oral biology and medicine
    
    R.H. Finnell et al., "NEURAL-TUBE AND CRANIOFACIAL DEFECTS WITH SPECIAL EMPHASIS ON FOLATE PATHWAY GENES", Critical reviews in oral biology and medicine, 9(1), 1998, pp. 38-53
97. BERGERON RJ; WIEGAND J; WEIMAR WR; SNYDER PS
    POLYAMINE ANALOG ANTIARRHYTHMICS
    Pharmacological research
    
    R.J. Bergeron et al., "POLYAMINE ANALOG ANTIARRHYTHMICS", Pharmacological research, 38(5), 1998, pp. 367-380
98. RICHARDSON DR
    ANALOGS OF PYRIDOXAL ISONICOTINOYL HYDRAZONE (PIH) AS POTENTIAL IRON CHELATORS FOR THE TREATMENT OF NEOPLASIA
    Leukemia & lymphoma
    
    D.R. Richardson, "ANALOGS OF PYRIDOXAL ISONICOTINOYL HYDRAZONE (PIH) AS POTENTIAL IRON CHELATORS FOR THE TREATMENT OF NEOPLASIA", Leukemia & lymphoma, 31(1-2), 1998, pp. 47-60
99. MOSCOW JA
    METHOTREXATE TRANSPORT AND RESISTANCE
    Leukemia & lymphoma
    
    J.A. Moscow, "METHOTREXATE TRANSPORT AND RESISTANCE", Leukemia & lymphoma, 30(3-4), 1998, pp. 215-224
100. NEWELL SW; PERCHELLET EM; LADESICH JB; FREEMAN JA; CHEN Y; LIU LZ; HUA DH; KRAFT SL; BASARABA RJ; PERCHELLET JP
     TRICYCLIC PYRONE ANALOGS - A NEW CLASS OF MICROTUBULE-DISRUPTING ANTICANCER DRUGS EFFECTIVE AGAINST MURINE LEUKEMIA-CELLS IN-VITRO
     International journal of oncology
     
     S.W. Newell et al., "TRICYCLIC PYRONE ANALOGS - A NEW CLASS OF MICROTUBULE-DISRUPTING ANTICANCER DRUGS EFFECTIVE AGAINST MURINE LEUKEMIA-CELLS IN-VITRO", International journal of oncology, 12(2), 1998, pp. 433-442