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    1. Thomas, T; Thomas, TJ
      Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications

      CELLULAR AND MOLECULAR LIFE SCIENCES
    2. Kartalou, M; Essigmann, JM
      Mechanisms of resistance to cisplatin

      MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
    3. Kilpelainen, PT; Saarimies, J; Kontusaari, SI; Jarvinen, MJ; Soler, AP; Kallioinen, MJ; Hietala, OA
      Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility

      INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
    4. Panasci, L; Paiement, JP; Christodouplopoulos, G; Belenkov, A; Malapetsa, A; Aloyz, R
      Chlorambucil drug resistance in chronic lymphocytic leukemia: The emergingrole of DNA repair

      CLINICAL CANCER RESEARCH
    5. Khokhar, NZ; She, Y; Rusch, VW; Sirotnak, FM
      Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: Further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums

      CLINICAL CANCER RESEARCH
    6. Perchellet, EM; Sperfslage, BJ; Qabaja, G; Jones, GA; Perchellet, JP
      Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cellsmore effectively than ellagic acid and genistein in vitro

      ANTI-CANCER DRUGS
    7. Belmokhtar, CA; Hillion, J; Segal-Bendirdjian, E
      Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms

      ONCOGENE
    8. Barancik, M; Bohacova, V; Kvackajova, J; Hudecova, S; Krizanova, O; Breier, A
      SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance

      EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    9. Wareski, P; Motyl, T; Ryniewicz, Z; Orzechowski, A; Gajkowska, B; Wojewodzka, U; Ploszaj, T
      Expression of apoptosis-related proteins in mammary gland of goat

      SMALL RUMINANT RESEARCH
    10. Oda, T; Tanaka, M; Sasaki, T
      Cytotoxicity of synthetic estrogen and related compounds in various tumor-derived cells

      BIOLOGICAL & PHARMACEUTICAL BULLETIN
    11. Golab, J; Zagozdzon, R; Kaminski, R; Kozar, K; Gryska, K; Izycki, D; Mackiewicz, A; Stoklosa, T; Giermasz, A; Lasek, W; Jakobisiak, M
      Potentiated antitumor effectiveness of combined chemo-immunotherapy with interleukin-12 and 5-fluorouracil of L1210 leukemia in vivo

      LEUKEMIA
    12. Bettuzzi, S; Strocchi, P; Davalli, P; Marinelli, M; Furci, L; Corti, A
      Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse

      BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
    13. Zhu, WY; Alliegro, MA; Melera, PW
      The rate of folate receptor alpha (FR alpha) synthesis in folate depleted CHL cells is regulated by a translational mechanism sensitive to media folate levels, while stable overexpression of its mRNA is mediated by gene amplification and an increase in transcript half-life

      JOURNAL OF CELLULAR BIOCHEMISTRY
    14. Rajgopal, A; Sierra, EE; Zhao, RB; Goldman, ID
      Expression of the reduced folate carrier SLC19A1 in IEC-6 cells results intwo distinct transport activities

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    15. Stater, LM; Stupecky, M; Sweet, P; Osann, K; Eklof, A; Arquilla, ER
      Etoposide induction of tumor immunity in Lewis lung cancer

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    16. de Nonancourt-Didion, M; Gueant, JL; Adjalla, C; Chery, C; Hatier, R; Namour, F
      Overexpression of folate binding protein alpha is one of the mechanism explaining the adaptation of HT29 cells to high concentration of methotrexate

      CANCER LETTERS
    17. Ikeda, K; Miura, K; Himeno, S; Imura, N; Naganuma, A
      Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    18. Shantz, LM; Feith, DJ; Pegg, AE
      Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy

      BIOCHEMICAL JOURNAL
    19. Stefanelli, C; Pignatti, C; Tantini, B; Fattori, M; Stanic, I; Mackintosh, CA; Flamigni, F; Guarnieri, C; Caldarera, CM; Pegg, AE
      Effect of polyamine depletion on caspase activation: a study with sperminesynthase-deficient cells

      BIOCHEMICAL JOURNAL
    20. Hall, JG; Cory, AH; Hickerson, DHM; Cory, JG
      Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells

      ANTICANCER RESEARCH
    21. Yuan, Q; Ray, RM; Viar, MJ; Johnson, LR
      Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells

      AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
    22. Matherly, LH
      Molecular and cellular biology of the human reduced folate carrier

      PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 67
    23. Mizutani, Y; Nakao, M; Ogawa, O; Yoshida, O; Bonavida, B; Miki, T
      Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin

      JOURNAL OF UROLOGY
    24. Valasinas, A; Sarkar, A; Reddy, VK; Marton, LJ; Basu, HS; Frydman, B
      Conformationally restricted analogues of N-1,N-14-bisethylhomospermine (BE-4-4-4): Synthesis and growth inhibitory effects on human prostate cancer cells

      JOURNAL OF MEDICINAL CHEMISTRY
    25. Burns, MR; Carlson, CL; Vanderwerf, SM; Ziemer, JR; Weeks, RS; Cai, F; Webb, HK; Graminski, GF
      Amino acid/spermine conjugates: Polyamine amides as potent spermidine uptake inhibitors

      JOURNAL OF MEDICINAL CHEMISTRY
    26. Martin, B; Posseme, F; Le Barbier, C; Carreaux, F; Carboni, B; Seiler, N; Moulinoux, JP; Delcros, JG
      N-benzylpolyamines as vectors of boron and fluorine for cancer therapy andimaging: Synthesis and biological evaluation

      JOURNAL OF MEDICINAL CHEMISTRY
    27. Bergeron, RJ; Muller, R; Huang, GF; McManis, JS; Algee, SE; Yao, H; Weimar, WR; Wiegand, J
      Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives

      JOURNAL OF MEDICINAL CHEMISTRY
    28. Zhao, RB; Gao, F; Wang, YH; Diaz, GA; Gelb, BD; Goldman, ID
      Impact of the reduced folate carrier on the accumulation of active thiaminmetabolites in murine leukemia cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    29. Zhao, RB; Russell, RG; Wang, YH; Liu, LB; Gao, F; Kneitz, B; Edelmann, W; Goldman, ID
      Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs

      JOURNAL OF BIOLOGICAL CHEMISTRY
    30. Cowan, DSM; Tannock, IF
      Factors that influence the penetration of methotrexate through solid tissue

      INTERNATIONAL JOURNAL OF CANCER
    31. Trippett, TM; Garcia, S; Manova, K; Mody, R; Cohen-Gould, L; Flintoff, W; Bertino, JR
      Localization of a human reduced folate carrier protein in the mitochondrial as well as the cell membrane of leukemia cells

      CANCER RESEARCH
    32. Zeng, H; Chen, ZS; Belinsky, MG; Rea, PA; Kruh, GD
      Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: Effect of polyglutamylation on MTX transport

      CANCER RESEARCH
    33. Candra, E; Matsunaga, K; Fujiwara, H; Mimaki, Y; Sashida, Y; Yamakuni, T; Ohizumi, Y
      Two steroidal saponins from Camassia cusickii induce L1210 cell death through the apoptotic mechanism

      CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
    34. Zhao, RB; Gao, F; Goldman, ID
      Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cells

      BIOCHEMICAL PHARMACOLOGY
    35. Wang, YH; Zhao, RB; Russell, RG; Goldman, ID
      Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis

      BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
    36. Lee, SY; Park, HS; Lee, SJ; Choi, MU
      Melittin exerts multiple effects on the release of free fatty acids from L1210 cells: Lack of selective activation of phospholipase A(2) by melittin

      ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
    37. Park, HS; Lee, SY; Kim, YH; Kim, JY; Lee, SJ; Choi, MU
      Membrane perturbation by mastoparan 7 elicits a broad alteration in lipid composition of L1210 cells

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
    38. Yarlett, N; Martinez, MP; Goldberg, B; Kramer, DL; Porter, CW
      Dependence of Trichomonas vaginalis upon polyamine backconversion

      MICROBIOLOGY-UK
    39. Zhao, RB; Babani, S; Gao, F; Liu, LB; Goldman, ID
      The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate

      CLINICAL CANCER RESEARCH
    40. Sirotnak, FM; Wendel, HG; Bornmann, WGB; Tong, WP; Miller, VA; Scher, HI; Kris, MG
      Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo

      CLINICAL CANCER RESEARCH
    41. Eskens, FALM; Greim, GA; van Zuylen, C; Wolff, I; Denis, LJ; Planting, AST; Muskiet, FA; Wanders, J; Barbet, NC; Choi, L; Capdeville, R; Verweij, J; Hanauske, AR; Bruntsch, U
      Phase I and pharmacological study of weekly administration of the polyamine synthesis inhibitor SAM 486A (CGP 48 664) in patients with solid tumors

      CLINICAL CANCER RESEARCH
    42. Golab, J; Zagozdzon, R; Kozar, K; Kaminski, R; Giermasz, A; Stoklosa, T; Lasek, W; Jakobisiak, M
      Potentiatied anti-tumor effectiveness of combined therapy with interleukin-12 and mitoxantrone of L1210 leukemia in vivo

      ONCOLOGY REPORTS
    43. Somerville, L; Cory, JG
      Altered sensitivity of deoxyadenosine-resistant mouse leukemia L1210 cellsto apoptosis induced by 7-hydroxystaurosporine

      INTERNATIONAL JOURNAL OF ONCOLOGY
    44. Oldham, TC; Phillips, D
      Triplet-state photophysics of aluminium phthalocyanine sensitizer in murine cancer cells

      JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
    45. Rajski, SR; Williams, RM
      Observations on the covalent cross-linking of the binding domain (BD) of the High Mobility Group I/Y (HMG I/Y) proteins to DNA by FR66979

      BIOORGANIC & MEDICINAL CHEMISTRY
    46. Perchellet, EM; Magill, MJ; Huang, XD; Dalke, DM; Hua, DH; Perchellet, JP
      1,4-Anthraquinone: an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of L1210 leukemic cells in the same nanomolar range as daunorubicin in vitro

      ANTI-CANCER DRUGS
    47. Ploszaj, T; Motyl, T; Zimowska, W; Skierski, J; Zwierzchowski, L
      Inhibition of ornithine decarboxylase by alpha-difluoromethylornithine induces apoptosis of HC11 mouse mammary epithelial cells

      AMINO ACIDS
    48. Bohacova, V; Kvackajova, J; Barancik, M; Drobna, Z; Breier, A
      Glutathione S-transferase does not play a role in multidrug resistance of L1210/VCR cell line

      PHYSIOLOGICAL RESEARCH
    49. Ben-Efraim, S; Bizzini, B; Relyveld, EH
      Use of xenogenized (modified) tumor cells for treatment in experimental tumor and in human neoplasia

      BIOMEDICINE & PHARMACOTHERAPY
    50. Farah, N; Dresner, HS; Searles, KJ; Winiarsky, R; Moosikasuwan, M; Cajigas, A; Hahm, S; Steinberg, JJ
      Cisplatin DNA adduct detection and depurination measured by P-32 DNA radiolabeling and two-dimensional thin-layer chromatography: A time and concentration study

      CANCER INVESTIGATION
    51. Tam, MN; Nam, NH; Jin, GZ; Song, GY; Ahn, BZ
      Synthesis and evaluation of the antitumor activity of 2-substituted 1,4-dihydroxy-9,10-anthraquinones

      ARCHIV DER PHARMAZIE
    52. Ray, RM; Viar, MJ; Yuan, Q; Johnson, LR
      Polyamine depletion delays apoptosis of rat intestinal epithelial cells

      AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
    53. Stromhaug, A; Warren, DJ
      A comparison of the effects of nine folate analogs on early and late murine hematopoietic progenitor cells in vitro

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    54. Malvy, C; Lefrancois, M; Bertrand, JR; Markovits, J
      Modified alkaline elution allows the measurement of intact apurinic sites in mammalian genomic DNA

      BIOCHIMIE
    55. Honscha, W; Dotsch, KU; Thomsen, N; Petzinger, E
      Cloning and functional characterization of the bile acid-sensitive methotrexate carrier from rat liver cells

      HEPATOLOGY
    56. Wheate, NJ; Webster, LK; Brodie, CR; Collins, JG
      Synthesis, DNA binding and cytotoxicity of isohelical DNA groove binding platinum complexes

      ANTI-CANCER DRUG DESIGN
    57. Moinet-Hedin, V; Tabka, T; Poulain, L; Godard, T; Lechevrel, M; Saturnino, C; Lancelot, JC; Le Talaer, JY; Gauduchon, P
      Biological properties of 5,11-dimethyl-6H-pyrido[3,2-b]carbazoles: a new class of potent antitumour drugs

      ANTI-CANCER DRUG DESIGN
    58. Kameoka, M; Ota, K; Tetsuka, T; Tanaka, Y; Itaya, A; Okamoto, T; Yoshihara, K
      Evidence for regulation of NF-kappa B by poly(ADP-ribose) polymerase

      BIOCHEMICAL JOURNAL
    59. Cory, AH; Hickerson, DHM; Cory, JG
      Apoptosis induced by inhibitors of nucleotide synthesis in deoxyadenosine-resistant leukemia L1210 cells that lack p53 expression

      ANTICANCER RESEARCH
    60. Karkabounas, S; Assimakopoulos, D; Malamas, M; Skaltsounis, AL; Leonce, S; Zelovitis, J; Stefanou, D; Evangelou, A
      Antiproliferative and anticarcinogenic effects of an aqueous preparation of Abies alba and Viscum album se abies, on a L-1210 malignant cell line andtumor-bearing Wistar rats

      ANTICANCER RESEARCH
    61. Somerville, L; Cory, JG
      Enhanced roscovitine-induced apoptosis is mediated by a caspase-3-like activity in deoxyadenosine-resistant mouse leukemia L1210 cells

      ANTICANCER RESEARCH
    62. Nikolaropoulos, S; Tsavdaridis, D; Arsenou, E; Papageorgiou, A; Karaberis, E; Mourelatos, D
      Synergistic antineoplastic and cytogenetic effects by the combined action of two homo-aza-steroidal esters of nitrogen mustards on P388 and L1210 leukaemias in vivo and in vitro

      ANTICANCER RESEARCH
    63. Horber, DH; Cattaneo-Pangrazzi, RMC; von Ballmoos, P; Schott, H; Ludwig, PS; Eriksson, S; Fichtner, I; Schwendener, RA
      Cytotoxicity, cell-cycle perturbations and apoptosis in human tumor cells by lipophilic N-4-alkyl-1-beta-D-arabinofuranosylcytosine derivatives and the new heteronucleoside phosphate dimer arabinocytidylyl-(5 '-> 5 ')-N-4-octadecyl-1-beta-D-arabinofuranosylcytosine

      JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
    64. Rosowsky, A; Wright, JE; Vaidya, CM; Forsch, RA
      The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine

      PHARMACOLOGY & THERAPEUTICS
    65. Zhao, QH; Bu, WM; Liao, DZ; Jiang, ZH; Yan, SP
      Synthesis and crystal structure of tetrakis(trifluoroacetato) bis(acetone)dirhodium(II)

      POLISH JOURNAL OF CHEMISTRY
    66. Khomutov, RM; Zhukov, YN; Khomutov, AR; Khurs, EN; Kramer, DL; Miller, JT; Porter, CW
      The inhibition of the L1210 cell growth by a phosphinic analogue of methionine and its transformation to the corresponding S-adenosylmethionine analogue

      BIOORGANICHESKAYA KHIMIYA
    67. Sharman, WM; Allen, CM; van Lier, JE
      Role of activated oxygen species in photodynamic therapy

      SINGLET OXYGEN, UV-A, AND OZONE
    68. Williams, RM; Rollins, SB; Judd, TC
      Synthesis of the first photo-triggered pro-mitosene based on FR-900482

      TETRAHEDRON
    69. Breier, A; Drobna, Z; Docolomansky, P; Barancik, M
      Cytotoxic activity of several unrelated drugs on L1210 mouse leukemic cellsublines with P-glycoprotein (PGP) mediated multidrug resistance (MDR) phenotype. A QSAR study

      NEOPLASMA
    70. Hoyt, MA; Williams-Abbott, LJ; Pitkin, JW; Davis, RH
      Cloning and expression of the S-adenosylmethionine decarboxylase gene of Neurospora crassa and processing of its product

      MOLECULAR AND GENERAL GENETICS
    71. Bergeron, RJ; Muller, R; Bussenius, J; McManis, JS; Merriman, RL; Smith, RE; Yao, H; Weimar, WR
      Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives

      JOURNAL OF MEDICINAL CHEMISTRY
    72. Bavetsias, V; Marriott, JH; Melin, C; Kimbell, R; Matusiak, ZS; Boyle, FT; Jackman, AL
      Design and synthesis of cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents

      JOURNAL OF MEDICINAL CHEMISTRY
    73. Kuhnel, JM; Chiao, JH; Sirotnak, FM
      Contrasting effects of oncogene expression on two carrier-mediated systemsinternalizing folate compounds in fisher rat 3T3 cells

      JOURNAL OF CELLULAR PHYSIOLOGY
    74. Vujcic, S; Halmekyto, M; Diegelman, P; Gan, G; Kramer, DL; Janne, J; Porter, CW
      Effects of conditional overexpression of spermidine/spermine N-1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs

      JOURNAL OF BIOLOGICAL CHEMISTRY
    75. Drori, S; Jansen, G; Mauritz, R; Peters, GJ; Assaraf, YG
      Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake

      JOURNAL OF BIOLOGICAL CHEMISTRY
    76. McCloskey, DE; Pegg, AE
      Altered spermidine/spermine N-1-acetyltransferase activity as a mechanism of cellular resistance to bis(ethyl)polyamine analogues

      JOURNAL OF BIOLOGICAL CHEMISTRY
    77. Bonneau, MJ; Poulin, R
      Spermine oxidation leads to necrosis with plasma membrane phosphatidylserine redistribution in mouse leukemia cells

      EXPERIMENTAL CELL RESEARCH
    78. Belmokhtar, CA; Torriglia, A; Counis, MF; Courtois, Y; Jacquemin-Sablon, A; Segal-Bendirdjian, E
      Nuclear translocation of a leukocyte elastase inhibitor/elastase complex during staurosporine-induced apoptosis: Role in the generation of nuclear L-DNase II activity

      EXPERIMENTAL CELL RESEARCH
    79. Drori, S; Sprecher, H; Shemer, G; Jansen, G; Goldman, ID; Assaraf, YG
      Characterization of a human alternatively spliced truncated reduced folatecarrier increasing folate accumulation in parental leukemia cells

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    80. Krejcova, R; Horska, K; Votruba, I; Holy, A
      Phosphorylation of purine (phosphonomethoxy)alkyl derivatives by mitochondrial AMP kinase (AK2 type) from L1210 cells

      COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
    81. Bergeron, RJ; Merriman, RL; Olson, SG; Wiegand, J; Bender, J; Streiff, RR; Weimar, WR
      Metabolism and pharmacokinetics of N-1,N-11-diethylnorspermine in a Cebus apella primate model

      CANCER RESEARCH
    82. Volk, EL; Rohde, K; Rhee, M; McGuire, JJ; Doyle, LA; Ross, DD; Schneider, E
      Methotrexate cross-resistance in a mitoxantrone-selected multidrug-resistant MCF7 breast cancer cell line is attributable to enhanced energy-dependent drug efflux

      CANCER RESEARCH
    83. Krejcova, R; Horska, K; Votruba, I; Holy, A
      Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenyzmes

      BIOCHEMICAL PHARMACOLOGY
    84. Wright, JE; Vaidya, CM; Chen, YN; Rosowsky, A
      Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N-alpha-(4-amino-4-deoxypteroyl)-N-delta-hemiphthaloyl-L-ornithine (PT523) and its B-ring analogues

      BIOCHEMICAL PHARMACOLOGY
    85. Finch, RA; Liu, MC; Grill, SP; Rose, WC; Loomis, R; Vasquez, KM; Cheng, YC; Sartorelli, AC
      Triapine (3-aminopyridine-2-carboxaldehydethiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity

      BIOCHEMICAL PHARMACOLOGY
    86. Barnes, MJ; Taylor, GA; Newell, DR
      Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells

      BIOCHEMICAL PHARMACOLOGY
    87. Dibas, A; Howard, J; Anwar, S; Stewart, D; Khan, A
      Borato-1,2-diaminocyclohexane platinum (II), a novel anti-tumor drug

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    88. Lee, TS; Kollman, PA
      Theoretical studies suggest a new antifolate as a more potent inhibitor ofthymidylate synthase

      JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
    89. Brzezinska, A; Winska, P; Balinska, M
      Cellular aspects of folate and antifolate membrane transport

      ACTA BIOCHIMICA POLONICA
    90. Froelich, JJ; Schneller, FRG; Zahn, RK
      The influence of radiation and chemotherapy-related DNA strand breaks on carcinogenesis: An evaluation

      CLINICAL CHEMISTRY AND LABORATORY MEDICINE
    91. Jansen, BAJ; van der Zwan, J; Reedijk, J; den Dulk, H; Brouwer, J
      A tetranuclear platinum compound designed to overcome cisplatin resistance

      EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
    92. Luo, FR; Yen, TY; Wyrick, SD; Chaney, SG
      High-performance liquid chromatographic separation of the biotransformation products of oxaliplatin

      JOURNAL OF CHROMATOGRAPHY B
    93. Sladek, NE
      Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines

      CURRENT PHARMACEUTICAL DESIGN
    94. Trippett, TM; Bertino, JR
      Therapeutic strategies targeting proteins that regulate folate and reducedfolate transport

      JOURNAL OF CHEMOTHERAPY
    95. Olivares, E; Kadiata, MM; Malaisse, WJ
      Potentiation by 2-deoxy-D-glucose tetraacetate of the antitumoral action of 5-fluorouracil in mice inoculated with L1210 ascites-producing cells

      ONCOLOGY REPORTS
    96. Crenshaw, TR; Cory, JG
      Mouse leukemia L1210 cells selected for resistance to the ribonucleotide reductase inhibitor, 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazoneshow altered response to DNA damaging agents

      INTERNATIONAL JOURNAL OF ONCOLOGY
    97. Perchellet, EM; Magill, MJ; Huang, XD; Brantis, CE; Hua, DH; Perchellet, JP
      Triptycenes: a novel synthetic class of bifunctional anticancer drugs thatinhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro

      ANTI-CANCER DRUGS
    98. Takemura, Y; Kobayashi, H; Miyachi, H
      Variable expression of the folylpolyglutamate synthetase gene at the levelof mRNA transcription in human leukemia cell lines sensitive, or made resistant, to various antifolate drugs

      ANTI-CANCER DRUGS
    99. Stoika, RS; Yakymovych, MY; Yakymovych, IA; Chekhun, VF
      Cisplatin-resistant derivatives of murine L1210 leukemia cells are not susceptible to growth-inhibiting and apoptosis-inducing actions of transforming growth factor-beta 1

      ANTI-CANCER DRUGS
    100. Perchellet, EM; Ladesich, JB; Collery, P; Perchellet, JP
      Microtubule-disrupting effects of gallium chloride in vitro

      ANTI-CANCER DRUGS


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Documento generato il 08/08/20 alle ore 09:25:59