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Involvement of a novel C-terminal kinase domain of Kir6.2 in the K-ATP channel rundown reactivation
JOURNAL OF MOLECULAR MODELING
Caged thiophosphotyrosine peptides
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
The three dimensional structure of the type I insulin-like growth factor receptor
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells
MOLECULAR CELL
Papillary renal cell carcinoma: Analysis of germline mutations in the MET proto-oncogene in a clinic-based population
GENETIC TESTING
Sharpin, a novel postsynaptic density protein that directly interacts withthe Shank family of proteins
MOLECULAR AND CELLULAR NEUROSCIENCE
Characterization of the separate kinase domain of chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
PROGRESS IN NATURAL SCIENCE
Differential requirement of the last C-terminal tail of Met receptor for cell transformation and invasiveness
ONCOGENE
C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET
ONCOGENE
Role of FGFs in the control of programmed cell death during limb development
DEVELOPMENT
Three novel mutations in the RET proto-oncogene
JOURNAL OF MOLECULAR MEDICINE-JMM
How familial cancer genes and environmentally induced oncogenes have changed the endocrine landscape
MODERN PATHOLOGY
Genetic markers in thyroid neoplasia
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
Human growth factor receptor bound 14 binds the activated insulin receptorand alters the insulin-stimulated tyrosine phosphorylation levels of multiple proteins
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
Familial medullary thyroid carcinoma (FMTC). Study of one family (treatment criteria)
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY
Molecular therapy for multiple myeloma
HAEMATOLOGICA
Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Intrasteric inhibition of ATP binding is not required to prevent unregulated autophosphorylation or signaling by the insulin receptor
MOLECULAR AND CELLULAR BIOLOGY
Specificity of Cdk activation in vivo by the two Caks Mcs6 and Csk1 in fission yeast
EMBO JOURNAL
A novel KIT mutation results in piebaldism with progressive depigmentation
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Calcium-mediated signal transduction in plants: A perspective on the role of Ca2+ and CDPKs during early plant development
JOURNAL OF PLANT PHYSIOLOGY
In vitro activity of MEKK2 and MEKK3 in detergents is a function of a valine to serine difference in the catalytic domain
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY
Discovery of a small molecule insulin receptor activator
RECENT PROGRESS IN HORMONE RESEARCH, VOL 56
Quasispecies heterogeneity of the carboxy-terminal part of the E2 gene including the PePHD and sensitivity of hepatitis C virus 1b isolates to antiviral therapy
VIROLOGY
Purification and characterization of a Ca2+-dependent protein kinase from sandalwood (Santalum album L.): evidence for Ca2+-induced conformational changes
PHYTOCHEMISTRY
Type a syndrome of insulin resistance: Anterior chamber anomalies of the eye and effects of insulin-like growth factor-1 on the retina
OPHTHALMOLOGICA
Molecular evolution of calmodulin-like domain protein kinases (CDPKs) in plants and protists
JOURNAL OF MOLECULAR EVOLUTION
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain
JOURNAL OF MOLECULAR BIOLOGY
Structure and function of cyclin-dependent Pho85 kinase of Saccharomyces cerevisiae
JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY
Familial medullary thyroid carcinoma with noncysteine RET mutations: Phenotype-genotype relationship in a large series of patients
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
Evidence for association of polycystic ovary syndrome in Caucasian women with a marker at the insulin receptor gene locus
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
Self-assembly and binding of a sorting nexin to sorting endosomes
JOURNAL OF CELL SCIENCE
Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly
JOURNAL OF CELL BIOLOGY
PDZ protein interactions regulating glutamate receptor function and plasticity
JOURNAL OF CELL BIOLOGY
p75 co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains
JOURNAL OF BIOLOGICAL CHEMISTRY
Role of receptor-interacting protein in tumor necrosis factor-alpha-dependent MEKK1 activation
JOURNAL OF BIOLOGICAL CHEMISTRY
Binding of ATP to the fructose-2,6-bisphosphatase domain of chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase leads to activation ofits 6-phosphofructo-2-kinase
JOURNAL OF BIOLOGICAL CHEMISTRY
Characterization of insulin-like growth factor I (IGF-I) receptor mutants for their effects on IGF-I- and interleukin 4-mediated DNA synthesis of 32Dcells
JOURNAL OF BIOLOGICAL CHEMISTRY
Molecular mechanisms regulating the differential association of kainate receptor subunits with SAP90/PSD-95 and SAP97
JOURNAL OF BIOLOGICAL CHEMISTRY
A novel alternatively spliced fibroblast growth factor receptor 3 isoform lacking the acid box domain is expressed during chondrogenic differentiation of ATDC5 cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Prognostic value of codon 918 (ATG -> ACG) RET proto-oncogene mutations insporadic medullary thyroid carcinoma
INTERNATIONAL JOURNAL OF CANCER
Genetic interactions of Spt4-Spt5 and TFIIS with the RNA polymerase IICTD and CTD modifying enzymes in Saccharomyces cerevisiae
GENETICS
Molecular identification of phenylalanine ammonia-lyase as a substrate of a specific constitutively active Arabidopsis CDPK expressed in maize protoplasts
FEBS LETTERS
Phosphorylation of plant actin-depolymerising factor by calmodulin-like domain protein kinase
FEBS LETTERS
The BPS domain of Grb10 inhibits the catalytic activity of the insulin andIGF1 receptors
FEBS LETTERS
A novel small molecule that directly sensitizes the insulin receptor in vitro and in vivo
DIABETES
Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa
CANCER
Allosteric regulatory step and configuration of the ATP-binding pocket in atrial natriuretic factor receptor guanylate cyclase transduction mechanism
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Properties of small molecules affecting insulin receptor function
BIOCHEMISTRY
Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Multiple endocrine neoplasias
SEMINARS IN SURGICAL ONCOLOGY
Fibroblast growth factors and their inhibitors
CURRENT PHARMACEUTICAL DESIGN
Human oral squamous cell carcinoma cell lines promote angiogenesis via expression of vascular endothelial growth factor and upregulation of KDR/flk-1expression in endothelial cells
ORAL ONCOLOGY
I kappa B/NF-kappa B mediated cisplatin resistance in HeLa cells after low-dose gamma-irradiation is associated with altered SODD expression
APOPTOSIS
Induced proximity model attracts NF-kappa B researchers
CELL DEATH AND DIFFERENTIATION
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
IMMUNITY
RET and GDNF gene scanning in Hirschprung patients using two dual denaturing gel systems
HUMAN MUTATION
Function of fibroblast growth factors and vascular endothelial growth factors and their receptors in angiogenesis
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
Structure of the Tie2 RTK domain: Self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail
STRUCTURE
Synaptic targeting and localization of Discs-large is a stepwise process controlled by different domains of the protein
CURRENT BIOLOGY
Spatiotemporal expression of noncatalytic TrkC NC2 isoform during early and late CNS neurogenesis: a comparative study with TrkC catalytic and p75(NTR) receptors
EUROPEAN JOURNAL OF NEUROSCIENCE
The Ron oncogenic activity induced by the MEN2B-like substitution overcomes the requirement for the multifunctional docking site
ONCOGENE
Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP
ONCOGENE
FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development
DEVELOPMENT
A RET double mutation in the germline of a kindred with FMTC
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
Comparative modeling studies of the calmodulin-like domain of calcium-dependent protein kinase from soybean
PROTEINS-STRUCTURE FUNCTION AND GENETICS
In vivo and in vitro phosphorylation and subcellular localization of trypanosomatid cytoskeletal giant proteins
CELL MOTILITY AND THE CYTOSKELETON
Functional characteristics of insulin receptors with a Thr -> Ser(1200) mutation overexpressed in Chinese hamster ovary cells
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Somatic trinucleotide change encompassing codons 882 and 883 of the RET proto-oncogene in a patient with sporadic medullary thyroid carcinoma
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): Differential conservation of CAKs in yeast and metazoa
MOLECULAR BIOLOGY AND EVOLUTION
Evolution of two-component signal transduction
MOLECULAR BIOLOGY AND EVOLUTION
mLin-7 is localized to the basolateral surface of renal epithelia via its NH2 terminus
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
C-cell hyperplasia, pheochromocytoma and sympathoadrenal malformation in amouse model of multiple endocrine neoplasia type 2B
EMBO JOURNAL
RTK mutations and human syndromes - when good receptors turn bad
TRENDS IN GENETICS
Trisomy 4 leading to duplication of a mutated KIT allele in acute myeloid leukemia with mast cell involvement
CANCER GENETICS AND CYTOGENETICS
The molecular and genetic basis of fibroblast growth factor receptor 3 disorders: The achondroplasia family of skeletal dysplasias, Muenke craniosynostosis, and Crouzon syndrome with acanthosis nigricans
ENDOCRINE REVIEWS
Differential effects of ethanol on insulin-like growth factor-I receptor signaling
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
Estimating local backbone structural deviation in homology models
COMPUTERS & CHEMISTRY
Signaling - 2000 and beyond
CELL
Purification and autophosphorylation of retinal guanylate cyclase
VERTEBRATE PHOTOTRANSDUCTION AND THE VISUAL CYCLE, PART A
Phosphorylation of the RAP74 subunit of TFIIF correlates with Tat-activated transcription of the HIV-1 long terminal repeat
VIROLOGY
Variable expressivity of familial medullary thyroid carcinoma (FMTC) due to a RET V804M (GTG -> ATG) mutation
SURGERY
The Drosophila Ret gene is transcribed in multiple alternatively spliced forms
MOLECULAR AND GENERAL GENETICS
Evolutionary analysis of the ErbB receptor and ligand families
JOURNAL OF MOLECULAR EVOLUTION
Ligand-induced conformational change in the minimized insulin receptor
JOURNAL OF MOLECULAR BIOLOGY
RET genotypes comprising specific haplotypes of polymorphic variants predispose to isolated Hirschsprung disease
JOURNAL OF MEDICAL GENETICS
Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesis
JOURNAL OF MEDICAL GENETICS
Ultrastructural localization of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) receptor-2 (FLK-1, KDR) in normal mouse kidney and in the hyperpermeable vessels induced by VPF/VEGF-expressing tumors and adenoviral vectors
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
Receptor-selective variants of human vascular endothelial growth factor - Generation and characterization
JOURNAL OF BIOLOGICAL CHEMISTRY
GAKIN, a novel kinesin-like protein associates with the human homologue ofthe Drosophila discs large tumor suppressor in T lymphocytes
JOURNAL OF BIOLOGICAL CHEMISTRY
The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor Flt-1
JOURNAL OF BIOLOGICAL CHEMISTRY
Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteins
JOURNAL OF BIOLOGICAL CHEMISTRY
Stable plasma membrane expression of the soluble domain of the human insulin receptor in yeast
FEBS LETTERS
The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor
FEBS LETTERS
Molecular genetics of neuroendocrine tumors
DIGESTION
Kinase mutant Btk results in atypical X-linked agammaglobulinaemia phenotype
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Development of dextran sulphate sodium-induced experimental colitis is suppressed in genetically mast cell-deficient Ws/Ws rats
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
CANCER RESEARCH
A two-hit model for development of multiple endocrine neoplasia type 2B byRET mutations
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES