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Histamine utilizes JAK-STAT pathway in regulating cytokine production
INTERNATIONAL IMMUNOPHARMACOLOGY
Negative regulation of onconstatin M signaling by suppressor of cytokine signaling (SOCS-3)
EUROPEAN CYTOKINE NETWORK
Signal transducers and activators of transcription (Stat) are detectable in mouse trigeminal ganglion neurons
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
Growth hormone receptor interaction with Jak proteins differs between tissues
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
Involvement of proteasomes in gene induction by interferon and double-stranded RNA
CYTOKINE
Biological and clinical significance of the JAK-STAT pathway; lessons fromknockout mice
INFLAMMATION RESEARCH
SOCSI regulates interferon-gamma mediated sensory-neuron survival
NEUROREPORT
Role and fate of PML nuclear bodies in response to interferon and viral infections
ONCOGENE
G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation
ONCOGENE
New developments in interferon therapy
EUROPEAN JOURNAL OF MEDICAL RESEARCH
Analysis of gene expression using high-density and IFN-gamma-specific low-density cDNA arrays
GENOMICS
Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells
LEUKEMIA
Chemokine signaling and functional responses: The role of receptor dimerization and TK pathway activation
ANNUAL REVIEW OF IMMUNOLOGY
Interleukin-15 and interleukin-2 enhance non-REM sleep in rabbits
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
JAK/STAT signaling pathway mediates cytokine-induced iNOS expression in primary astroglial cell cultures
JOURNAL OF NEUROSCIENCE RESEARCH
Prolactin receptor heterogeneity: processing and signalling of the long and short isoforms during development
BIOCHEMICAL SOCIETY TRANSACTIONS
Advanced glycation end product-induced proliferation in NRK-49F cells is dependent on the JAK2/STAT5 pathway and cyclin D1
AMERICAN JOURNAL OF KIDNEY DISEASES
Activation of STAT proteins and growth control
BIOESSAYS
The JAK/STAT pathway and Drosophila development
BIOESSAYS
LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1
BIOCHEMICAL JOURNAL
Cytokine-like effects of prolactin in human mononuclear and polymorphonuclear leukocytes
JOURNAL OF NEUROIMMUNOLOGY
Expression of serine protease inhibitor 3 in ocular tissues in endotoxin-induced uveitis in rat
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Receptor dimerization: A key step in chemokine signaling
CELLULAR AND MOLECULAR BIOLOGY
Signaling pathway of ciliary neurotrophic factor in neuroblastoma cell lines
MEDICAL AND PEDIATRIC ONCOLOGY
Viruses and interferons
ANNUAL REVIEW OF MICROBIOLOGY
HTLV-1 cell lines differ in constitutively activated signaling pathways that can be altered by cytokine exposure
VIROLOGY
Herpes simplex virus type 1 suppresses the interferon signaling pathway byinhibiting phosphorylation of STATs and janus kinases during an early infection stage
VIROLOGY
How hepatitis C virus counteracts the interferon response: The jury is still out on NS5A
VIROLOGY
Triflusal posttreatment inhibits glial nuclear factor-kappa B, downregulates the glial response, and is neuroprotective in an excitotoxic injury model in postnatal brain
STROKE
Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Methimazole as an antioxidant and immunomodulator in thyroid cells: Mechanisms involving interferon-gamma signaling and H2O2 scavenging
MOLECULAR PHARMACOLOGY
Myocardial ischemia activates the JAK-STAT pathway through angiotensin II signaling in in vivo myocardium of rats
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Constitutive and interleukin-7-and interleukin-15-stimulated DNA binding of STAT and novel factors in cutaneous T cell lymphoma cells
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways
JOURNAL OF CLINICAL INVESTIGATION
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
JOURNAL OF BIOLOGICAL CHEMISTRY
G-protein-independent activation of Tyk2 by the platelet-activating factorreceptor
JOURNAL OF BIOLOGICAL CHEMISTRY
The signal transduction of the growth hormone receptor is regulated by theubiquitin/proteasome system and continues after endocytosis
JOURNAL OF BIOLOGICAL CHEMISTRY
Members of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway are present and active in human sperm
FERTILITY AND STERILITY
Phosphorylation of signal transducer and activator of transcription-3 (Stat3) after focal cerebral ischemia in rats
EXPERIMENTAL NEUROLOGY
Tissue-specific induction of SOCS gene expression by PRL
ENDOCRINOLOGY
Intracellular BMP signaling regulation in vertebrates: Pathway or network?
DEVELOPMENTAL BIOLOGY
Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism
CLINICAL BIOCHEMISTRY
ERK and p38 MAPK, but not NF-kappa B, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts
CIRCULATION RESEARCH
Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo
CIRCULATION RESEARCH
Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T-cell lymphoma cells
BLOOD
The deubiquitinating enzyme DUB-2 prolongs cytokine-induced signal transducers and activators of transcription activation and suppresses apoptosis following cytokine withdrawal
BLOOD
Low doses of EPO activate MAP kinases but not JAK2-STAT5 in rat vascular smooth muscle cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Comparative genome-scale analysis of gene expression profiles in T cell lymphoma cells during malignant progression using a complementary DNA microarray
AMERICAN JOURNAL OF PATHOLOGY
Unraveling distinct intracellular signals that promote survival and proliferation: Study of erythropoietin, stem cell factor, and constitutive signaling in leukemic cells
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH
Treatment of infections in the patient with Mendelian susceptibility to mycobacterial infection
MICROBES AND INFECTION
Upregulation and activation of Stat6 precede vascular smooth muscle cell proliferation in carotid artery injury model
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
The effect of burn injury on suppressors of cytokine signalling
SHOCK
A novel role for STAT3 in cardiac remodeling
TRENDS IN CARDIOVASCULAR MEDICINE
Role of the cytoplasmic domains of the type I interferon receptor subunitsin signalling
SEMINARS IN CANCER BIOLOGY
gp130-dependent signalling pathway is not enhanced in gp130 transgenic heart after LIF stimulation
CYTOKINE
The Janus kinase inhibitor, JAB/SOCS-1, is an interferon-gamma inducible gene and determines the sensitivity to interferons
LEUKEMIA & LYMPHOMA
Cytokines and their receptors in cardiovascular diseases - role of gp130 signalling pathway in cardiac myocyte growth and maintenance
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
Janus kinases: components of multiple signaling pathways
ONCOGENE
The role of STATs in transcriptional control and their impact on cellular function
ONCOGENE
MHC class I - Subversive gene functions of cytomegalovirus and their regulation by interferons - an intricate balance
VIRUS GENES
Activation of Stat3 and Stat1 DNA binding and transcriptional activity in human brain tumour cell lines by gp130 cytokines
CELLULAR SIGNALLING
The MHC class I heavy chain is a common target of the small proteins encoded by the 3 ' end of HTLV type 1 and HTLV type 2
AIDS RESEARCH AND HUMAN RETROVIRUSES
Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B
MOLECULAR ENDOCRINOLOGY
Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STATpathways
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
STAT signalling in the mature and aging brain
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
Negative regulation of cytokine signaling pathways
ANNUAL REVIEW OF IMMUNOLOGY
Mediators of the mitogenic action of human V-1 vascular vasopressin receptors
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
A unifying hypothesis for the renin-angiotensin system and hematopoiesis: sticking the pieces together with the JAK-STAT pathway
MEDICAL HYPOTHESES
Leptin activates Stat3, Stat1 and AP-1 in mouse adipose tissue
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Signaling mechanisms of cytokine receptors and their perturbances in disease
MOLECULAR AND CELLULAR ENDOCRINOLOGY
The role of Jak/STAT signaling in heart tissue renin-angiotensin system
MOLECULAR AND CELLULAR BIOCHEMISTRY
Hepatitis C virus resistance to antiviral therapy
HEPATOLOGY
Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7
MOLECULAR AND CELLULAR BIOLOGY
Cross-talk between interleukin 1 beta (IL-1 beta) and IL-6 signalling pathways: IL-1 beta selectively inhibits IL-6-activated signal transducer and activator of transcription factor 1 (STAT1) by a proteasome-dependent mechanism
BIOCHEMICAL JOURNAL
A single amino acid substitution (Trp(666) -> Ala) In the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction
BIOCHEMICAL JOURNAL
Cardiotrophin-1 increases angiotensinogen mRNA in rat cardiac myocytes through STAT3 - An autocrine loop for hypertrophy
HYPERTENSION
Activation of the Jak-Stat- and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells
MOLECULAR BRAIN RESEARCH
Activated STAT1 suppresses proliferation of cultured rat mesangial cells
KIDNEY INTERNATIONAL
Down-regulation of interferon-gamma signaling by gene transfer of Stat1 mutant in mesangial cells
KIDNEY INTERNATIONAL
The GABA(B) receptor interacts directly with the related transcription factors CREB2 and ATFx
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-alpha signaling
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Activation of signal transducers and activators of transcription by alpha(1A)-adrenergic receptor stimulation in PC12 cells
MOLECULAR PHARMACOLOGY
Cytokines that signal through the leukemia inhibitory factor receptor-betacomplex in the nervous system
JOURNAL OF NEUROCHEMISTRY
Molecular characterization of STAT5A-and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains
JOURNAL OF MOLECULAR EVOLUTION
Angiotensin blockade inhibits SIF DNA binding activities via STAT3 after myocardial infarction
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type IIFN receptor
JOURNAL OF IMMUNOLOGY
Inhibition of IFN-gamma-induced Janus kinase-1-STAT1 activation in macrophages by vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide
JOURNAL OF IMMUNOLOGY
Differentiation of monocytes to macrophages switches the Mycobacterium tuberculosis effect on HIV-1 replication from stimulation to inhibition: Modulation of interferon response and CCAAT/enhancer binding protein beta expression
JOURNAL OF IMMUNOLOGY
Expression of "suppressor of cytokine signalling" (SOCS) genes in the developing and adult mouse nervous system
JOURNAL OF COMPARATIVE NEUROLOGY
The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized Madin-Darby canine kidney cells
JOURNAL OF CELL SCIENCE
Multiple regulatory domains control IRF-7 activity in response to virus infection
JOURNAL OF BIOLOGICAL CHEMISTRY
Protein-tyrosine phosphatase PTP epsilon C inhibits Jak-STAT signaling anddifferentiation induced by interleukin-6 and leukemia inhibitory factor inM1 leukemia cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Identification of critical residues required for suppressor of cytokine signaling-specific regulation of interleukin-4 signaling
JOURNAL OF BIOLOGICAL CHEMISTRY
Role of the intracellular domain of the human type I interferon receptor 2chain (IFNAR2c) in interferon signaling - Expression of IFNAR2c truncationmutants in U5A cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Inhibition of interleukin-6 signaling by galiellalactone
FEBS LETTERS
Trichodion, a new inhibitor of inflammatory signal transduction pathways from a Trichosporiella species
FEBS LETTERS
Termination of IL-6-induced STAT activation is independent of receptor internalization but requires de novo protein synthesis
FEBS LETTERS
STAT3 regulates the growth and immunoglobulin production of BCL1 B cell lymphoma through control of cell cycle progression
CELLULAR IMMUNOLOGY
Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction
CARDIOVASCULAR RESEARCH
Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways
CARDIOVASCULAR RESEARCH