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    1. Shashkin, PN; Wasner, HK; Ortmeyer, HK; Hansen, BC
      Prostaglandylinositol cyclic phosphate (cPIP): a novel second messenger ofinsulin action. Comparative analysis of two kinds of 'insulin mediators'

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    2. Paez-Espinosa, V; Rocha, EM; Velloso, LA; Saad, MJA
      Regulation of insulin-stimulated tyrosine phosphorylation of Shc and Shc/Grb2 association in liver, muscle, and adipose tissue of epinephrine- and streptozotocin-treated rats

      ENDOCRINE
    3. Romano, G; Reiss, K; Tu, X; Peruzzi, F; Belletti, B; Wang, JY; Zanocco-Marani, T; Baserga, R
      Efficient in vitro and in vivo gene regulation of a retrovirally deliveredpro-apoptotic factor under the control of the Drosophila HSP70 promoter

      GENE THERAPY
    4. Litherland, GJ; Hajduch, E; Hundal, HS
      Intracellular signalling mechanisms regulating glucose transport in insulin-sensitive tissues

      MOLECULAR MEMBRANE BIOLOGY
    5. Gingras, SB; Cote, S; Simard, J
      Multiple signal transduction pathways mediate interleukin-4-induced 3 beta-hydroxysteroid dehydrogenase/Delta 5-Delta 4 isomerase in normal and tumoral target tissues

      JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
    6. Reiss, K; Wang, JY; Romano, G; Tu, X; Peruzzi, F; Baserga, R
      Mechanisms of regulation of cell adhesion and motility by insulin receptorsubstrate-1 in prostate cancer cells

      ONCOGENE
    7. Morrione, A; Navarro, M; Romano, G; Dews, M; Reiss, K; Valentinis, B; Belletti, B; Baserga, R
      The role of the insulin receptor substrate-1 in the differentiation of rathippocampal neuronal cells

      ONCOGENE
    8. Wang, JY; Del Valle, L; Gordon, J; Rubini, M; Romano, G; Croul, S; Peruzzi, F; Khalili, K; Reiss, K
      Activation of the IGF-IR system contributes to malignant growth of human and mouse medulloblastomas

      ONCOGENE
    9. Melillo, RM; Carlomagno, F; De Vita, G; Formisano, P; Vecchio, G; Fusco, A; Billaud, M; Santoro, M
      The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret

      ONCOGENE
    10. Sesti, G; Federici, M; Hribal, ML; Lauro, D; Sbraccia, P; Lauro, R
      Defects of the insulin receptor substrate (IRS) system in human metabolic disorders

      FASEB JOURNAL
    11. Sykiotis, GP; Papavassiliou, AG
      Serine phosphorylation of insulin receptor substrate-1: A novel target forthe reversal of insulin resistance

      MOLECULAR ENDOCRINOLOGY
    12. Ouwens, DM; van der Zon, GCM; Maassen, JA
      Modulation of insulin-stimulated glycogen synthesis by Src homology phosphatase 2

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    13. Tu, YZ; Liang, L; Frank, SJ; Wu, CY
      Src homology 3 domain-dependent interaction of Nck-2 with insulin receptorsubstrate-1

      BIOCHEMICAL JOURNAL
    14. Suryawan, A; Nguyen, HV; Bush, JA; Davis, TA
      Developmental changes in the feeding-induced activation of the insulin-signaling pathway in neonatal pigs

      AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
    15. Ouwens, DM; de Mesquita, DSG; Dekker, J; Maassen, JA
      Hyperosmotic stress activates the insulin receptor in CHO cells

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
    16. Park, CR
      Cognitive effects of insulin in the central nervous system

      NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
    17. Le Roith, D; Zick, Y
      Recent advances in our understanding of insulin action and insulin resistance

      DIABETES CARE
    18. Nunes, ALB; Carvalheira, JBC; Carvalho, CRO; Brenelli, SL; Saad, MJA
      Tissue-specific regulation of early steps in insulin action in septic rats

      LIFE SCIENCES
    19. Carrillo, MC; Favre, C; Monti, JA; Alvarez, ML; Carnovale, CE
      Insulin hyperresponsiveness in partially hepatectomized diabetic rats

      LIFE SCIENCES
    20. Barzik, M; Carl, UD; Schubert, WD; Frank, R; Wehland, J; Heinz, DW
      The N-terminal domain of Homer/Vesl is a new class II EVH1 domain

      JOURNAL OF MOLECULAR BIOLOGY
    21. Armon, A; Graur, D; Ben-Tal, N
      ConSurf: An algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic information

      JOURNAL OF MOLECULAR BIOLOGY
    22. Pelegrinelli, FFF; Thirone, ACP; Gasparetti, AL; Araujo, EP; Velloso, LA; Saad, MJA
      Early steps of insulin action in the skin of intact rats

      JOURNAL OF INVESTIGATIVE DERMATOLOGY
    23. Kawazoe, Y; Naka, T; Fujimoto, M; Kohzaki, H; Morita, Y; Narazaki, M; Okumura, K; Saitoh, H; Nakagawa, R; Uchiyama, Y; Akira, S; Kishimoto, T
      Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1(IRS-1) phosphorylation

      JOURNAL OF EXPERIMENTAL MEDICINE
    24. Miranda, C; Creco, A; Miele, C; Pierotti, MA; Van Obberghen, E
      IRS-1 and IRS-2 are recruited by TrkA receptor and oncogenic TRK-T1

      JOURNAL OF CELLULAR PHYSIOLOGY
    25. Ravichandran, LV; Esposito, DL; Chen, J; Quon, MJ
      Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin

      JOURNAL OF BIOLOGICAL CHEMISTRY
    26. Jacobs, AR; LeRoith, D; Taylor, SI
      Insulin receptor substrate-1 pleckstrin homology and phosphotyrosine-binding domains are both involved in plasma membrane targeting

      JOURNAL OF BIOLOGICAL CHEMISTRY
    27. Oriente, F; Formisano, P; Miele, C; Fiory, F; Maitan, MA; Vigliotta, G; Trencia, A; Santopietro, S; Caruso, M; Van Obberghen, E; Beguinot, F
      Insulin receptor substrate-2 phosphorylation is necessary for protein kinase C zeta activation by insulin in L6hIR cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    28. Vainshtein, I; Kovacina, KS; Roth, RA
      The insulin receptor substrate (IRS)-1 pleckstrin homology domain functions in downstream signaling

      JOURNAL OF BIOLOGICAL CHEMISTRY
    29. Osipo, C; Dorman, S; Frankfater, A
      Loss of insulin-like growth factor II receptor expression promotes growth in cancer by increasing intracellular signaling from both IGF-I and insulinreceptors

      EXPERIMENTAL CELL RESEARCH
    30. Van Obberghen, E; Baron, V; Delahaye, L; Emanuelli, B; Filippa, N; Giorgetti-Peraldi, S; Lebrun, P; Mothe-Satney, I; Peraldi, P; Rocchi, S; Sawka-Verhelle, D; Tartare-Deckert, S; Giudicelli, J
      Surfing the insulin signaling web

      EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
    31. Esposito, DL; Li, YH; Cama, A; Quon, MJ
      Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells

      ENDOCRINOLOGY
    32. Sasaoka, T; Ishiki, M; Wada, T; Hori, H; Hirai, H; Haruta, T; Ishihara, H; Kobayashi, M
      Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis

      ENDOCRINOLOGY
    33. Kaburagi, Y; Satoh, S; Yamamoto-Honda, R; Ito, T; Ueki, K; Akanuma, Y; Sekihara, H; Kimura, S; Kadowaki, T
      Insulin-independent and wortmannin-resistant targeting of IRS-3 to the plasma membrane via its pleckstrin homology domain mediates a different interaction with the insulin receptor from that of IRS-1

      DIABETOLOGIA
    34. Baroni, MG; Arca, M; Sentinelli, F; Buzzetti, R; Capici, F; Lovari, S; Vitale, M; Romeo, S; Di Mario, U
      The G972R variant of the Insulin Receptor Substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance

      DIABETOLOGIA
    35. Stumvoll, M; Fritsche, A; Volk, A; Stefan, N; Madaus, A; Maerker, E; Teigeler, A; Koch, M; Machicao, F; Haring, H
      The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans

      DIABETES
    36. Mauro, L; Salerno, M; Panno, ML; Bellizzi, D; Sisci, D; Miglietta, A; Surmacz, E; Ando, S
      Estradiol increases IRS-1 gene expression and insulin signaling in breast cancer cells

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    37. Grigsby, RJ; Dobrowsky, RT
      Inhibition of ceramide production reverses TNF-induced insulin resistance

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    38. Li, ZG; Qiang, XL; Sima, AAF; Grunberger, G
      C-peptide attenuates protein tyrosine phosphatase activity and enhances glycogen synthesis in L6 myoblasts

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    39. Hartman, ME; Villela-Bach, M; Chen, J; Freund, GG
      FRAP-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
    40. Giovannone, B; Scaldaferri, ML; Federici, M; Porzio, O; Lauro, D; Fusco, A; Sbraccia, P; Borboni, P; Lauro, R; Sesti, G
      Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

      DIABETES-METABOLISM RESEARCH AND REVIEWS
    41. Gosbell, AD; Favilla, I; Baxter, KM; Jablonski, P
      Insulin receptor and insulin receptor substrate-1 in rat retinae

      CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
    42. Carvalho, CRO; Maeda, L; Brenelli, SL; Saad, MJA
      Tissue-specific regulation of IRS-2/PI 3-kinase association in aged rats

      BIOLOGICAL CHEMISTRY
    43. Surmacz, E
      Function of the IGF-I receptor in breast cancer

      JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
    44. Zhou, MM
      Phosphothreonine recognition comes into focus

      NATURE STRUCTURAL BIOLOGY
    45. Fruman, DA; Mauvais-Jarvis, F; Pollard, DA; Yballe, CM; Brazil, D; Bronson, RT; Kahn, CR; Cantley, LC
      Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

      NATURE GENETICS
    46. Ueno, H; Kondo, E; Yamamoto-Honda, R; Tobe, K; Nakamoto, T; Sasaki, K; Mitani, K; Furusaka, A; Tanaka, T; Tsujimoto, Y; Kadowaki, T; Hirai, H
      Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function

      MOLECULAR BIOLOGY OF THE CELL
    47. Benecke, H; Topak, H; zur Muhlen, AV; Schuppert, F
      A study on the genetics of obesity: Influence of polymorphisms of the beta-3-adrenergic receptor and insulin receptor substrate 1 in relation to weight loss, waist to hip ratio and frequencies of common cardiovascular risk factors

      EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
    48. Kato, H; Okubo, Y; Matsumura, Y; Roberts, CT; Sugahara, K; LeRoith, D
      The tyrosine kinase activity of the chicken insulin receptor is similar tothat of the human insulin receptor

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
    49. Haruta, T; Uno, T; Kawahara, J; Takano, A; Egawa, K; Sharma, PM; Olefsky, JM; Kobayashi, M
      A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1

      MOLECULAR ENDOCRINOLOGY
    50. Razzini, G; Ingrosso, A; Brancaccio, A; Sciacchitano, S; Esposito, DL; Falasca, M
      Different subcellular localization and phosphoinositides binding of insulin receptor substrate protein pleckstrin homology domains

      MOLECULAR ENDOCRINOLOGY
    51. Zeng, WM; Peng, J; Wan, XX; Chen, SH; Song, HP
      The mutation of insulin receptor substrate-1 gene in Chinese patients withnon-insulin-dependent diabetes mellitus

      CHINESE MEDICAL JOURNAL
    52. Ariga, M; Nedachi, T; Akahori, M; Sakamoto, H; Ito, Y; Hakuno, F; Takahashi, S
      Signalling pathways of insulin-like growth factor-I that are augmented by cAMP in FRTL-5 cells

      BIOCHEMICAL JOURNAL
    53. Morisco, C; Condorelli, G; Orzi, F; Vigliotta, G; Di Grezia, R; Beguinot, F; Trimarco, B; Lembo, G
      Insulin-stimulated cardiac glucose uptake is impaired in spontaneously hypertensive rats: role of early steps of insulin signalling

      JOURNAL OF HYPERTENSION
    54. Hamada, K; Shimizu, T; Matsui, T; Tsukita, S; Tsukita, S; Hakoshima, T
      Structural basis of the membrane-targeting and unmasking mechanisms of theradixin FERM domain

      EMBO JOURNAL
    55. Park, CR; Seeley, RJ; Craft, S; Woods, SC
      Intracerebroventricular insulin enhances memory in a passive-avoidance task

      PHYSIOLOGY & BEHAVIOR
    56. Krutzfeldt, J; Raasch, W; Klein, HH
      Ramipril increases the protein level of skeletal muscle IRS-1 and alters protein tyrosine phosphatase activity in spontaneously hypertensive rats

      NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
    57. Szanto, I; Kahn, CR
      Selective interaction between leptin and insulin signaling pathways in a hepatic cell line

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    58. Hribal, ML; Federici, M; Porzio, O; Lauro, D; Borboni, P; Accili, D; Lauro, R; Sesti, G
      The Gly -> Arg(972) amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells

      JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
    59. Kausch, C; Hamann, A; Uphues, I; Niendorf, A; Muller-Wieland, D; Joost, HG; Algenstaedt, P; Dreyer, M; Rudiger, HW; Haring, HU; Eckel, J; Matthaei, S
      Association of impaired phosphatidylinositol 3-kinase activity in GLUT1-containing vesicles with malinsertion of glucose transporters into the plasmamembrane of fibroblasts from a patient with severe insulin resistance and clinical features of Werner syndrome

      JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
    60. Goldstein, BJ; Bittner-Kowalczyk, A; White, MF; Harbeck, M
      Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B - Possible facilitation by the formation of a ternary complex with the GRB2 adaptor protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    61. Farhang-Fallah, J; Yin, XH; Trentin, G; Cheng, AM; Rozakis-Adcock, M
      Cloning and characterization of PHIP, a novel insulin receptor substrate-1pleckstrin homology domain interacting protein

      JOURNAL OF BIOLOGICAL CHEMISTRY
    62. Zhang, H; Hoff, H; Sell, C
      Insulin-like growth factor I-mediated degradation of insulin receptor substrate-1 is inhibited by epidermal growth factor in prostate epithelial cells

      JOURNAL OF BIOLOGICAL CHEMISTRY
    63. Wang, LQ; Shao, JH; Muhlenkamp, P; Liu, S; Klepcyk, P; Ren, JM; Friedman, JE
      Increased insulin receptor substrate-1 and enhanced skeletal muscle insulin sensitivity in mice lacking CCAAT/enhancer-binding protein beta

      JOURNAL OF BIOLOGICAL CHEMISTRY
    64. Bosc, DG; Graham, KC; Saulnier, RB; Zhang, CJ; Prober, D; Gietz, RD; Litchfield, DW
      Identification and characterization of CKIP-1, a novel pleckstrin homologydomain-containing protein that interacts with protein kinase CK2

      JOURNAL OF BIOLOGICAL CHEMISTRY
    65. Molloy, CA; May, FEB; Westley, BR
      Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line

      JOURNAL OF BIOLOGICAL CHEMISTRY
    66. White, MK; Strayer, DS
      Surfactant protein a regulates pulmonary surfactant secretion via activation of phosphatidylinositol 3-kinase in type II alveolar cells

      EXPERIMENTAL CELL RESEARCH
    67. Fehm, HL; Perras, B; Smolnik, R; Kern, W; Born, J
      Manipulating neuropeptidergic pathways in humans: a novel approach to neuropharmacology?

      EUROPEAN JOURNAL OF PHARMACOLOGY
    68. Egawa, K; Nakashima, N; Sharma, PM; Maegawa, H; Nagai, Y; Kashiwagi, A; Kikkawa, R; Olefsky, JM
      Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes

      ENDOCRINOLOGY
    69. Knight, JB; Cao, KT; Gibson, GV; Olson, AL
      Expression of a prenylation-deficient Rab4 interferes with propagation of insulin signaling through insulin receptor substrate-1

      ENDOCRINOLOGY
    70. Dean, DJ; Cartee, GD
      Calorie restriction increases insulin-stimulated tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 in rat skeletal muscle

      ACTA PHYSIOLOGICA SCANDINAVICA
    71. Greco, P; Vimercati, A; Giorgino, F; Perrini, S; Scioscia, M; Selvaggi, L
      Intrauterine growth restriction and insulin-like growth factors

      FETUS AS A PATIENT
    72. Baroni, MG; D'Andrea, MP; Montali, A; Pannitteri, G; Barilla, F; Campagna, F; Mazzei, E; Lovari, S; Seccareccia, F; Campa, PP; Ricci, G; Pozzilli, P; Urbinati, G; Arca, M
      A common mutation of the insulin receptor substrate-1 gene is a risk factor for coronary artery disease

      ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
    73. van der Geer, P; Wiley, S; Pawson, T
      Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site

      ONCOGENE
    74. Folli, F; Saad, MJA; Velloso, L; Hansen, H; Carandente, O; Feener, EP; Kahn, CR
      Crosstalk between insulin and angiotensin II signalling systems

      EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
    75. Nelms, K; O'Neill, TJ; Li, SQ; Hubbard, SR; Gustafson, TA; Paul, WE
      Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain

      MAMMALIAN GENOME
    76. de la Monte, SM; Ganju, N; Wands, JR
      Microtiter immunocytochemical ELISA assay

      BIOTECHNIQUES
    77. Nelms, K; Keegan, AD; Zamorano, J; Ryan, JJ; Paul, WE
      The IL-4 receptor: Signaling mechanisms and biologic functions

      ANNUAL REVIEW OF IMMUNOLOGY
    78. Paez-Espinosa, EV; Rocha, EM; Velloso, LA; Boschero, AC; Saad, MJA
      Insulin-induced tyrosine phosphorylation of Shc in liver, muscle and adipose tissue of insulin resistant rats

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    79. Li, DX; Dobrowolska, G; Krebs, EG
      Identification of proteins that associate with protein kinase CK2

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    80. Abbott, MA; Wells, DG; Fallon, JR
      The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

      JOURNAL OF NEUROSCIENCE
    81. Begum, N; Ragolia, L
      Role of Janus kinase-2 in insulin-mediated phosphorylation and inactivation of protein phosphatase-2A and its impact on upstream insulin signalling components

      BIOCHEMICAL JOURNAL
    82. Herbst, R; Zhang, XL; Qin, J; Simon, MA
      Recruitment of the protein tyrosine phosphatase CSW by DOS is an essentialstep during signaling by the Sevenless receptor tyrosine kinase

      EMBO JOURNAL
    83. Shpakov, AO; Pertseva, MN
      The structure-function characterization of proteins, substrates of insulinreceptor, and molecular mechanisms of their interaction with insulin superfamily tyrosine kinase receptors and effector proteins

      BIOLOGICHESKIE MEMBRANY
    84. Del Aguila, LF; Claffey, KP; Kirwan, JP
      TNF-alpha impairs insulin signaling and insulin stimulation of glucose uptake in C2C12 muscle cells

      AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
    85. Houmard, JA; Shaw, CD; Hickey, MS; Tanner, CJ
      Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in human skeletal muscle

      AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
    86. Liu, ZH; Guan, TJ; Chen, ZH; Li, LS
      Glucose transporter (GLUT1) allele (XbaI-) associated with nephropathy in non-insulin-dependent diabetes mellitus

      KIDNEY INTERNATIONAL
    87. Dhe-Paganon, S; Ottinger, EA; Nolte, RT; Eck, MJ; Shoelson, SE
      Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
    88. Spector, SA; Olson, ET; Gumbs, AA; Friess, H; Buchler, MW; Seymour, NE
      Human insulin receptor and insulin signaling proteins in hepatic disease

      JOURNAL OF SURGICAL RESEARCH
    89. Baskin, DG; Schwartz, MW; Seeley, RJ; Woods, SC; Porte, D; Breininger, JF; Jonak, Z; Schaefer, J; Krouse, M; Burghardt, C; Campfield, LA; Burn, P; Kochan, JP
      Leptin receptor long-form splice-variant protein expression in neuron cellbodies of the brain and co-localization with neuropeptide Y mRNA in the arcuate nucleus

      JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
    90. Dupont, J; Derouet, M; Simon, J; Taouis, M
      Corticosterone alters insulin signaling in chicken muscle and liver at different steps

      JOURNAL OF ENDOCRINOLOGY
    91. Kulkami, RN; Winnay, JN; Daniels, M; Bruning, JC; Flier, SN; Hanahan, D; Kahn, CR
      Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

      JOURNAL OF CLINICAL INVESTIGATION
    92. Qu, BH; Karas, M; Koval, A; LeRoith, D
      Insulin receptor substrate-4 enhances insulin-like growth factor-I-inducedcell proliferation

      JOURNAL OF BIOLOGICAL CHEMISTRY
    93. Liu, SCH; Wang, Q; Lienhard, GE; Keller, SR
      Insulin receptor substrate 3 is not essential for growth or glucose homeostasis

      JOURNAL OF BIOLOGICAL CHEMISTRY
    94. Brown, RA; Domino, J; Arcaro, A; Waterfield, MD; Shepherd, PR
      Insulin activates the alpha isoform of class II phosphoinositide 3-kinase

      JOURNAL OF BIOLOGICAL CHEMISTRY
    95. Li, JP; DeFea, K; Roth, RA
      Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

      JOURNAL OF BIOLOGICAL CHEMISTRY
    96. Farooq, A; Plotnikova, O; Zeng, L; Zhou, MM
      Phosphotyrosine binding domains of Shc and insulin receptor substrate 1 recognize the NPXpY motif in a thermodynamically distinct manner

      JOURNAL OF BIOLOGICAL CHEMISTRY
    97. Salerno, M; Sisci, D; Mauro, L; Guvakova, MA; Ando, S; Surmacz, E
      Insulin receptor substrate 1 is a target for the pure antiestrogen ICI 182,780 in breast cancer cells

      INTERNATIONAL JOURNAL OF CANCER
    98. Urso, B; Brown, RA; O'Rahilly, S; Shepherd, PR; Siddle, K
      The alpha-isoform of class II phosphoinositide 3-kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs

      FEBS LETTERS
    99. Yau, L; Lukes, H; McDiarmid, H; Werner, J; Zahradka, P
      Insulin-like growth factor-I (IGF-I)-dependent activation of pp42/44 mitogen-activated protein kinase occurs independently of IGF-I receptor kinase activation and IRS-1 tyrosine phosphorylation

      EUROPEAN JOURNAL OF BIOCHEMISTRY
    100. Fantin, VR; Lavan, BE; Wang, Q; Jenkins, NA; Gilbert, DJ; Copeland, NG; Keller, SR; Lienhard, GE
      Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene

      ENDOCRINOLOGY


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Documento generato il 11/08/20 alle ore 03:27:19