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Genetic manipulation of the renin-angiotensin system
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
Effects of gestation on ovine fetal and maternal angiotensin receptor subtypes in the heart and major blood vessels
EXPERIMENTAL PHYSIOLOGY
Genetic engineering in hypertension research
INTERNAL MEDICINE
Mechanism of the cardioprotective effect of inhibition of the renin-angiotensin system on ischemia/reperfusion-induced myocardial injury
Hypertension research
Role of the angiotensin AT(2) receptor in blood pressure regulation and therapeutic implications
AMERICAN JOURNAL OF HYPERTENSION
Tonic suppression of spontaneous baroreceptor reflex by endogenous angiotensins via AT(2) subtype receptors at nucleus reticularis ventrolateralis inthe rat
SYNAPSE
Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
AT(2) receptor-mediated vasodilation in the heart: effect of myocardial infarction
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Role of the renin-angiotensin system during alterations of sodium intake in conscious mice
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
Electrophysiological characterization of murine myocardial ischemia and infarction
BASIC RESEARCH IN CARDIOLOGY
Determination of catecholamines and their 3-O-methyl metabolites in mouse plasma
BIOMEDICAL CHROMATOGRAPHY
Left ventricular function in mice lacking the AT(2) receptor
JOURNAL OF HYPERTENSION
Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase
HYPERTENSION
Normal blood pressure and renal function in mice lacking the bradykinin B-2 receptor
HYPERTENSION
Angiotensin and its AT(2) receptor: new insights into an old system
REGULATORY PEPTIDES
Genetic deletion of angiotensin AT2 receptor leads to increased cell numbers in different brain structures of mice
REGULATORY PEPTIDES
Transgenic mouse models of angiotensin receptor subtype function in the cardiovascular system
REGULATORY PEPTIDES
Measuring normal and pathological anxiety-like behaviour in mice: a review
BEHAVIOURAL BRAIN RESEARCH
Angiotensin receptors: distribution, signalling and function
CLINICAL SCIENCE
The genetic factor in acute myocardial infarction with hypertension
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
Perinatal dietary NaCl level: effect on angiotensin-induced thermal and dipsogenic responses in adult rats
PHYSIOLOGY & BEHAVIOR
Intracellular third loops in AT1 and AT2 receptors determine subtype specificity
LIFE SCIENCES
Elevated sympathetic nervous activity in mice deficient in alpha CGRP
CIRCULATION RESEARCH
Canine ventricular myocytes possess a renin-angiotensin system that is upregulated with heart failure
CIRCULATION RESEARCH
AT(2), judgment day - Which angiotensin receptor is the culprit in cardiachypertrophy?
CIRCULATION
Combined angiotensin converting enzyme inhibition and angiotensin AT(1) receptor blockade up-regulates myocardial AT(2) receptors in remodeled myocardium post-infarction
CARDIOVASCULAR RESEARCH
Pivotal role of tyrosine phosphatase SHP-1 in AT2 receptor-mediated apoptosis in rat fetal vascular smooth muscle cell
CARDIOVASCULAR RESEARCH
Effect of angiotensin II type 2 receptor on tyrosine kinase Pyk2 and c-JunNH2-terminal kinase via SHP-1 tyrosine phosphatase activity: Evidence fromvascular-targeted transgenic mice of AT2 receptor
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Increased vasoconstrictor sensitivity in obstructive sleep apnea
JOURNAL OF APPLIED PHYSIOLOGY
X chromosome genes and premature ovarian failure
SEMINARS IN REPRODUCTIVE MEDICINE
Inflammation influences vascular remodeling through AT(2) receptor expression and signaling
PHYSIOLOGICAL GENOMICS
A phenotype map of the mouse X chromosome: Models for human X-linked disease
GENOME RESEARCH
Transgenic animals in cardiovascular disease research
EXPERIMENTAL PHYSIOLOGY
Blocking the tissue renin-angiotensin system: the future cornerstone of therapy
JOURNAL OF HUMAN HYPERTENSION
The role of the AT(2) receptor in hypertension
AMERICAN JOURNAL OF HYPERTENSION
Localization and function of angiotensin AT(1) receptors
AMERICAN JOURNAL OF HYPERTENSION
Angiotensin II receptor subtypes determine induced NO production in rat glomerular mesangial cells
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Expression and localization of angiotensin subtype receptor proteins in the hypertensive rat heart
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
The acute vascular effects of frusemide in heart failure
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Transactivation of EGF receptor induced by angiotensin II regulates fibronectin and TGF-beta gene expression via transcriptional and post-transcriptional mechanisms
MOLECULAR AND CELLULAR BIOCHEMISTRY
Kidney angiotensin receptors and their role in renal pathophysiology
SEMINARS IN NEPHROLOGY
Long-term blood pressure telemetry in AT(2) receptor-disrupted mice
JOURNAL OF HYPERTENSION
Towards understanding the kallikrein-kinin system: insights from measurement of kinin peptides
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
Importance of quantitative genetic variations in the etiology of hypertension
KIDNEY INTERNATIONAL
Understanding hypertension through genetic manipulation in mice
KIDNEY INTERNATIONAL
Inhibition of pressure natriuresis in mice lacking the AT(2) receptor
KIDNEY INTERNATIONAL
Pain threshold, learning and formation of brain edema in mice lacking the angiotensin II type 2 receptor
LIFE SCIENCES
Vascular reactivity of isolated thoracic aorta of the C57BL/6J mouse
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Effect of pressure overload on angiotensin receptor expression in the rat heart during early postnatal life
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Localization of G protein alpha-subunits in the human fetal adrenal gland
ENDOCRINOLOGY
Functional reconstitution of the angiotensin II type 2 receptor and G(i) activation
CIRCULATION RESEARCH
Interferon-gamma induces AT(2) receptor expression in fibroblasts by Jak/STAT pathway and interferon regulatory factor-1
CIRCULATION RESEARCH
Inhibition of p53 function prevents renin-angiotensin system activation and stretch-mediated myocyte apoptosis
AMERICAN JOURNAL OF PATHOLOGY
Up-regulation of AT1 and AT(2) receptors in postinfarcted hypertrophied myocytes and stretch-mediated apoptotic cell death
AMERICAN JOURNAL OF PATHOLOGY
Gene targeting approaches to analyzing hypertension
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Effects of candesartan on the proteinuria of chronic glomerulonephritis
JOURNAL OF HUMAN HYPERTENSION
What have we learned from gene targeting studies for the renin angiotensinsystem of the kidney?
INTERNAL MEDICINE
Influence of active immunization against angiotensin AT(1) or AT(2) receptor on hypertension development in young and adult SHR
PHYSIOLOGICAL RESEARCH
Proapoptotic effects of ANG II in human coronary artery endothelial cells:role of AT(1) receptor and PKC activation
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Distribution of angiotensin AT(1) and AT(2) receptor subtypes in the rat kidney
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Angiotensin receptors: Molecular biology and signalling
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Differential kinetics of circulating angiotensin IV and II after treatmentwith angiotensin II Type 1 receptor antagonist and their plasma levels in patients with chronic renal failure
CLINICAL NEPHROLOGY
The X chromosome and ovarian failure
CLINICAL ENDOCRINOLOGY
Characterization of AT(2) receptor expression in NIH 3T3 fibroblasts
CELLULAR AND MOLECULAR NEUROBIOLOGY
Renin-angiotensin genes in renal development and the occurrence and progression of renal diseases
SEMINARS IN NEPHROLOGY
Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages
JOURNAL OF HYPERTENSION
AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats
HYPERTENSION
AT(2) receptor and vascular smooth muscle cell differentiation in vasculardevelopment
HYPERTENSION
Differential regulation of renal angiotensin subtype AT(1A) and AT(2) receptor protein in rats with angiotensin-dependent hypertension
HYPERTENSION
Interferon regulatory factors regulate interleukin-1 beta-converting enzyme expression and apoptosis in vascular smooth muscle cells
HYPERTENSION
Transgenic and knockout models in renin-angiotensin system
IMMUNOPHARMACOLOGY
The renin-angiotensin system and its receptors
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Renal renin-angiotensin system dysregulation caused by partial bladder outlet obstruction in fetal sheep
KIDNEY INTERNATIONAL
Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth
JOURNAL OF CLINICAL INVESTIGATION
Lipopolysaccharides and cytokines downregulate the angiotensin II type 2 receptor in rat cardiac fibroblasts
EUROPEAN JOURNAL OF PHARMACOLOGY
Interactions between AT(1) and AT(2) receptors in uterine arteries from pregnant ewes
EUROPEAN JOURNAL OF PHARMACOLOGY
Angiotensin II-induced transactivation of epidermal growth factor receptorregulates fibronectin and transforming growth factor-beta synthesis via transcriptional and posttranscriptional mechanisms
CIRCULATION RESEARCH
Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing
CIRCULATION RESEARCH
Anxiety-like behavior in mice lacking the angiotensin II type-2 receptor
BRAIN RESEARCH
Role of angiotensin AT(1) and AT(2) receptors in cardiac hypertrophy and disease
AMERICAN JOURNAL OF CARDIOLOGY
TRANSGENESIS AND GENE TARGETING IN THE MOUSE - TOOLS FOR STUDYING GENETIC-DETERMINANTS OF HYPERTENSION
Trends in cardiovascular medicine
REVERSAL OF CONVENTION - FROM MAN TO EXPERIMENTAL ANIMAL IN ELUCIDATING THE FUNCTION OF THE RENAL AMILORIDE-SENSITIVE SODIUM-CHANNEL
Experimental nephrology
WHAT CAN WE EXPECT FROM SUBTYPE-2 ANGIOTENSIN RECEPTORS (AT(2))
Journal of molecular medicine
GENETIC DELETION AND OVEREXPRESSION OF ANGIOTENSIN-II RECEPTORS
Journal of molecular medicine
ACE knockout mice - lessons for adult nephrology
NEPHROLOGY DIALYSIS TRANSPLANTATION
DEPRESSOR ROLE OF ANGIOTENSIN AT(2) RECEPTORS IN THE (MREN-2)27 TRANSGENIC RAT
American journal of hypertension
VENTRICULAR REMODELING IN A MOUSE MODEL OF MYOCARDIAL-INFARCTION
American journal of physiology. Heart and circulatory physiology
EFFECTS OF ACUTE AT(1) RECEPTOR BLOCKADE BY CANDESARTAN ON ARTERIAL-PRESSURE AND RENAL-FUNCTION IN RATS
American journal of physiology. Renal, fluid and electrolyte physiology
DOCUMENTATION OF ANGIOTENSIN-II RECEPTORS IN GLOMERULAR EPITHELIAL-CELLS
American journal of physiology. Renal, fluid and electrolyte physiology
EFFECTS OF CHRONIC INHIBITION OF ACE AND AT(1) RECEPTORS ON GLOMERULAR INJURY IN DAHL SALT-SENSITIVE RATS
American journal of physiology. Regulatory, integrative and comparative physiology
ANGIOTENSIN RECEPTORS IN THE NERVOUS-SYSTEM
Brain research bulletin
HYPERTENSION AND THE RENIN-ANGIOTENSIN SYSTEM - EVIDENCE FROM GENETICAND TRANSGENIC STUDIES
Basic research in cardiology
MOLECULAR APPROACHES TO RENAL PHYSIOLOGY AND THERAPEUTICS
Seminars in nephrology
Mapping tissue angiotensin-converting enzyme and angiotensin AT(1), AT(2) and AT(4) receptors
JOURNAL OF HYPERTENSION
Role of angiotensin in the development of the kidney and urinary tract
NEPHROLOGIE
CHRONIC SODIUM-BALANCE AND BLOOD-PRESSURE RESPONSE TO CAPTOPRIL IN CONSCIOUS MICE
Hypertension
A memorial to Robert Tiegerstedt - The centennial of renin discovery
HYPERTENSION
SCIATIC-NERVE TRANSECTION EVOKES LASTING UP-REGULATION OF ANGIOTENSINAT(2) AND AT(1) RECEPTOR MESSENGER-RNA IN ADULT-RAT DORSAL-ROOT GANGLIA AND SCIATIC-NERVES
Molecular brain research
ANGIOTENSIN RECEPTORS AND NOREPINEPHRINE NEUROMODULATION - IMPLICATIONS OF FUNCTIONAL COUPLING
Regulatory peptides