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Molecular structure and gas-phase reactivity of clonidine and rilmenidine:Two-layered ONIOM calculations
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
The TGF beta receptor activation process: An inhibitor- to substrate-binding switch
MOLECULAR CELL
Evidence for gradients of gene expression correlating with zonal topography of the olfactory sensory map
MOLECULAR AND CELLULAR NEUROSCIENCE
Protein tyrosine phosphatase activity in human endometrium
REPRODUCTION FERTILITY AND DEVELOPMENT
Expression of bone morphogenetic protein receptors in the developing mousemetanephros
EXPERIMENTAL NEPHROLOGY
An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors
EUROPEAN JOURNAL OF NEUROSCIENCE
The transcription factor Schnurri plays a dual role in mediating Dpp signaling during embryogenesis
DEVELOPMENT
Lost-a-fin encodes a type IBMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation
DEVELOPMENT
Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region
DEVELOPMENT
A positive role for short gastrulation in modulating BMP signaling during dorsoventral patterning in the Drosophila embryo
DEVELOPMENT
mtv shapes the activity gradient of the Dpp morphogen through regulation of thickveins
DEVELOPMENT
I-1 receptors, cardiovascular function, and metabolism
AMERICAN JOURNAL OF HYPERTENSION
Sequential actions of BMP receptors control neural precursor cell production and fate
GENES & DEVELOPMENT
Functional inactivation, of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes
GENES & DEVELOPMENT
Growth hormone induces bone morphogenetic proteins and bone-related proteins in the developing rat periodontium
JOURNAL OF BONE AND MINERAL RESEARCH
Expression and localization of activin receptors during endochondral bone development
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Chimeric G alpha(q) subunits can distinguish the long form of the Xenopus Me11c melatonin receptor from the mammalian mt1 and MT2 melatonin receptors
JOURNAL OF PINEAL RESEARCH
beta-carboline binding to imidazoline receptors
DRUG AND ALCOHOL DEPENDENCE
BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and-independent pathways
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Hormonal control of ovarian cell production of insulin-like growth factor binding proteins
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Central imidazoline (I-1) receptors modulate aqueous hydrodynamics
CURRENT EYE RESEARCH
Extracellular ATP or ADP induce chemotaxis of cultured microglia through G(i/o)-coupled P2Y receptors
JOURNAL OF NEUROSCIENCE
BMP4 mediates apoptotic cell death in the developing chick eye
JOURNAL OF NEUROSCIENCE
Activation of group I metabotropic glutamate receptors produces a direct excitation and disinhibition of GABAergic projection neurons in the substantia nigra pars reticulata
JOURNAL OF NEUROSCIENCE
Down-regulation of MAO-B activity and imidazoline receptors in rat brain following chronic treatment of morphine
ACTA PHARMACOLOGICA SINICA
Perspectives in the biological function, the technical and therapeutic application of bone morphogenetic proteins
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Evidence for the involvement of central I-1 imidazoline receptor in ethanol counteraction of clonidine hypotension in spontaneously hypertensive rats
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
Expression of the insulin receptor in the retina of the goldfish
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Interaction of the insulin receptor beta-subunit with phosphatidylinositol3-kinase in bovine ROS
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
Alcohol impairs protein synthesis and degradation in cultured skeletal muscle cells
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
Role of heparan sulfate proteoglycans in cell signaling and cancer
ADVANCES IN CANCER RESEARCH, VOL 83
Expression of bone morphogenetic proteins during membranous bone healing
PLASTIC AND RECONSTRUCTIVE SURGERY
Selective involvement of mGlu1 receptors in corticostriatal LTD
NEUROPHARMACOLOGY
Conditionally expressed G alpha(15) couples to endogenous receptors in GH(3) cells
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Distribution of genes for bone morphogenetic protein-4,-6, growth differentiation factor-5, and bone morphogenetic protein receptors in the process of experimental spondylosis in mice
JOURNAL OF NEUROSURGERY
Coincident signalling between the Gi/Go-coupled delta-opioid receptor and the Gq-coupled m3 muscarinic receptor at the level of intracellular free calcium in SH-SY5Y cells
JOURNAL OF NEUROCHEMISTRY
Synthesis and biological evaluation of pyrrolinic isosteres of rilmenidine. Discovery of cis-/trans-dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)-amine (LNP 509), an I-1 imidazoline receptor selective ligand with hypotensive activity
JOURNAL OF MEDICINAL CHEMISTRY
BMP3: To be or not to be a BMP
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
Proteasomal degradation of Smad1 induced by bone morphogenetic proteins.
JOURNAL OF BIOLOGICAL CHEMISTRY
Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases
JOURNAL OF BIOLOGICAL CHEMISTRY
Smad-mediated transcription is required for transforming growth factor-beta 1-induced p57(Kip2) proteolysis in osteoblastic cells
JOURNAL OF BIOLOGICAL CHEMISTRY
Differential [H-3]idazoxan and [H-3]2-(2-benzofuranyl)-2-imidazoline (2-BFI) binding to imidazoline I-2 receptors in human postmortem frontal cortex
EUROPEAN JOURNAL OF PHARMACOLOGY
Imidazoline I-1 receptor-induced activation of phosphatidylcholine-specific phospholipase C elicits mitogen-activated protein kinase phosphorylation in PC12 cells
EUROPEAN JOURNAL OF PHARMACOLOGY
Effects of cartilage-derived morphogenetic proteins and osteogenic protein-1 on osteochondrogenic differentiation of periosteum-derived cells
ENDOCRINOLOGY
Evidence for a non-adrenoceptor, imidazoline-mediated contractile responseto oxymetazoline in the porcine isolated rectal artery
BRITISH JOURNAL OF PHARMACOLOGY
G alpha(14) links a variety of G(i)- and G(s)-coupled receptors to the stimulation of phospholipase C
BRITISH JOURNAL OF PHARMACOLOGY
Plasma insulin-like growth factor binding protein-3 proteolysis is increased in primary breast cancer
BRITISH JOURNAL OF CANCER
Is G alpha(16) the optimal tool for fishing ligands of orphan G-protein-coupled receptors?
TRENDS IN PHARMACOLOGICAL SCIENCES
Mesenchymal precursor cells in the blood of normal individuals
ARTHRITIS RESEARCH
Schnurri interacts with Mad in a Dpp-dependent manner
GENES TO CELLS
Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs
MOLECULAR CELL
Insulin-like growth factor system in growth, development and carcinogenesis
JOURNAL OF CLINICAL LIGAND ASSAY
Bone morphogenetic protein receptor complexes on the surface of live cells: A new oligomerization mode for serine/threonine kinase receptors
MOLECULAR BIOLOGY OF THE CELL
Divergent cell-specific effects of activin-A on thymocyte proliferation stimulated by phytohemagglutinin, and interleukin 1 beta or interleukin 6 in vitro
CYTOKINE
Diversity of the p70 killer cell inhibitory receptor (KIR3DL) family members in a single individual
MOLECULES AND CELLS
Analysis of ALK-1 and endoglin in newborns from families with hereditary hemorrhagic telangiectasia type 2
HUMAN MOLECULAR GENETICS
Glyceraldehyde-3-phosphate dehydrogenase gene expression in human breast cancer
EUROPEAN JOURNAL OF CANCER
Interactions between imidazoline binding sites and dopamine levels in the rat nucleus accumbens
EUROPEAN JOURNAL OF NEUROSCIENCE
The juxtamembrane but not the carboxyl-terminal domain of the insulin receptor mediates insulin's metabolic functions in primary adipocytes and cultured hepatoma cells
JOURNAL OF MOLECULAR ENDOCRINOLOGY
Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family
ONCOGENE
A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehogexpression in the mouse tooth germ
DEVELOPMENT
The type IBMP receptor BMPRIB is required for chondrogenesis in the mouse limb
DEVELOPMENT
Opposing effects of bone morphogenetic proteins on neuron production and survival in the olfactory receptor neuron lineage
DEVELOPMENT
BMP4 rescues a non-cell-autonomous function of Msx1 in tooth development
DEVELOPMENT
The Decapentaplegic morphogen gradient regulates the notal wingless expression through induction of pannier and u-shaped in Drosophila
MECHANISMS OF DEVELOPMENT
Corticosteroids regulate the gene expression of FGF-1 and FGF-2 in cultured rat astrocytes
JOURNAL OF MOLECULAR NEUROSCIENCE
TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest
GENES & DEVELOPMENT
Decreased insulin-like growth factor-I receptor sites on circulating mononuclear cells from children with acute leukemia
PEDIATRIC HEMATOLOGY AND ONCOLOGY
Utilization of bone morphogenetic protein receptors during chondrocyte maturation
JOURNAL OF BONE AND MINERAL RESEARCH
Heterotopic ossification of degenerating rat skeletal muscle induced by adenovirus-mediated transfer of bone morphogenetic protein-2 gene
JOURNAL OF BONE AND MINERAL RESEARCH
Cytokine-specific induction of the TCF-beta inducible early gene (TIEG): Regulation by specific members of the TGF-beta family
JOURNAL OF CELLULAR BIOCHEMISTRY
Discrete region of the insulin receptor carboxyl terminus plays key role in insulin action
JOURNAL OF CELLULAR BIOCHEMISTRY
Exon-intron organization of the human gp130 gene
GENE
Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl acid) in the in vitro neonatal spinal cord and in an in vivo pain model
NEUROSCIENCE
I-2-Imidazoline receptors and monoamine oxidase B enzyme sites in human brain: covariation with age
NEUROSCIENCE LETTERS
One year growth hormone replacement therapy does not alter colonic epithelial cell proliferation in growth hormone deficient adults
CLINICAL ENDOCRINOLOGY
Runx2 is a common target of transforming growth factor beta 1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
MOLECULAR AND CELLULAR BIOLOGY
Insulin-like growth factors and insulin-like growth factor binding proteins in the endometrium. Effect of intrauterine levonorgestrel delivery
HUMAN REPRODUCTION
Regulation of activin's access to the cell: why is mother nature such a control freak?
BIOESSAYS
Direct transcriptional control of the Dpp target omb by the DNA binding protein Brinker
EMBO JOURNAL
Differently labeled peptide ligands for rapid investigation of receptor expression on a new human glioblastoma cell line
PEPTIDES
Immunosuppressive macromolecules of endometrial and conceptus origins in livestock species
JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Effects of moxonidine on corticocerebral blood flow under normal and ischemic conditions in conscious rabbits
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
The role of growth hormone and insulin-like growth factors for placental growth and development
PLACENTA
Mechanism of transforming growth factor-beta 1 signaling: Role of the mitogen-activated protein kinase
KIDNEY INTERNATIONAL
Transgenic mouse models to study human mineralocorticoid receptor functionin vivo
KIDNEY INTERNATIONAL
Identification of hereditary hemorrhagic telangiectasia type 1 in newbornsby protein expression and mutation analysis of endoglin
PEDIATRIC RESEARCH
Tyrosine phosphorylation of the alpha subunit of transducin and its association with Src in photoreceptor rod outer segments
JOURNAL OF NEUROCHEMISTRY
CD8(+) T cells rapidly acquire NK1.1 and NK cell-associated molecules uponstimulation in vitro and in vivo
JOURNAL OF IMMUNOLOGY
BMP-2/ALK3 and HGF signal in parallel to regulate renal collecting duct morphogenesis
JOURNAL OF CELL SCIENCE
Different sensitivity of the transforming growth factor-ss cell cycle arrest pathway to c-Myc and IMDM-2
JOURNAL OF BIOLOGICAL CHEMISTRY
Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line
JOURNAL OF BIOLOGICAL CHEMISTRY
FKBP12 is a negative regulator of transforming growth factor-beta receptorinternalization
JOURNAL OF BIOLOGICAL CHEMISTRY
A porcine intrauterine 4-MDa component with transforming growth factor-beta activity suppresses natural killer cell responses
JOURNAL OF ANIMAL SCIENCE
Effects of intra-vestibular nucleus injection of the Group I metabotropic glutamate receptor antagonist AIDA on vestibular compensation in guinea pigs
EXPERIMENTAL BRAIN RESEARCH
Signaling of transforming growth factor-beta family members through Smad proteins
EUROPEAN JOURNAL OF BIOCHEMISTRY
The zinc finger protein schnurri nets as a smad partner in mediating the transcriptional response to decapentaplegic
DEVELOPMENTAL BIOLOGY
Bmp-4 requires the presence of the digits to initiate programmed cell death in limb interdigital tissues
DEVELOPMENTAL BIOLOGY