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Expression of aryl hydrocarbon receptor nuclear translocator (ARNT) isoforms in juvenile and adult rainbow trout tissues
MARINE BIOTECHNOLOGY
Molecular mechanisms in the early phase of hemorrhagic shock
LANGENBECKS ARCHIVES OF SURGERY
Development of the primate retinal vasculature
PROGRESS IN RETINAL AND EYE RESEARCH
Mechanism, origin, and evolution of anoxia tolerance in animals
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Partial HIF-1 alpha deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Insights into the role of the von Hippel-Lindau gene product - A key player in hypoxic regulation
EXPERIMENTAL NEPHROLOGY
Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy
GENE THERAPY
Nitric oxide and the regulation of gene expression
TRENDS IN CELL BIOLOGY
Angiogenesis: the role of the microenvironment in flipping the switch
CURRENT OPINION IN GENETICS & DEVELOPMENT
Angiogenesis and G-protein-coupled receptors: signals that bridge the gap
ONCOGENE
Anaemia in end-stage renal disease: pathophysiological considerations
NEPHROLOGY DIALYSIS TRANSPLANTATION
Molecular biology of polycythemias
INTERNAL MEDICINE
Hypoxia reduces hormone responsiveness of human breast cancer cells
JAPANESE JOURNAL OF CANCER RESEARCH
Role of AP-1 and HIF-1 transcription factors in TGF-beta activation of VEGF expression
GROWTH FACTORS
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
FASEB JOURNAL
Transduction pathways involved in hypoxia-inducible FACTOR-1 phosphorylation and activation
FREE RADICAL BIOLOGY AND MEDICINE
Seeking a cellular oxygen sensor
SCIENTIST
Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors
JOURNAL OF LEUKOCYTE BIOLOGY
Biomarker analysis demonstrates a hypoxic environment in the castrated ratventral prostate gland
JOURNAL OF CELLULAR BIOCHEMISTRY
HIF-1 expression in healing wounds: HIF-1 alpha induction in primary inflammatory cells by TNF-alpha
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
Transcriptional regulation of heme oxygenases by HIF-1 alpha in renal medullary interstitial cells
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
Mitochondrial contributions to cancer cell physiology: potential for drug development
ADVANCED DRUG DELIVERY REVIEWS
Angiogenesis and leukemia
LEUKEMIA RESEARCH
Differential expression of lactate dehydrogenase isozymes (LDH) in human placenta with high expression of LDH-A(4) isozyme in the endothelial cells of pre-eclampsia villi
PLACENTA
Inhibition of HIF-1-and wild-type p53-stimulated transcription by codon Arg175 p53 mutants with selective loss of functions
CARCINOGENESIS
Cellular mechanisms of oxygen sensing
ANNUAL REVIEW OF PHYSIOLOGY
Gene therapy and the aging nervous system
MECHANISMS OF AGEING AND DEVELOPMENT
Gene expression of VEGF and its receptors Flk-1/KDR and Flt-1 in cultured and transplanted rat islets
TRANSPLANTATION
Pathogenetic mechanisms of polycythemia vera and congenital polycythemic disorders
SEMINARS IN HEMATOLOGY
HIF-1 alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The regulation of the induction of vascular endothelial growth factor at the onset of diabetes in spontaneously diabetic rats
LIFE SCIENCES
Two cysteine residues in the DNA-binding domain of CREB control binding toCRE and CREB-mediated gene expression
JOURNAL OF MOLECULAR BIOLOGY
The splice variants of vascular endothelial growth factor (VEGF) and theirreceptors
JOURNAL OF CELL SCIENCE
Regulation of vascular endothelial growth factor expression by advanced glycation end products
JOURNAL OF BIOLOGICAL CHEMISTRY
A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-1 alpha
FEBS LETTERS
Transcriptional effect of hypoxia on placental leptin
FEBS LETTERS
Binding and regulation of HIF-1 alpha, by a subunit of the proteasome complex, PSMA7
FEBS LETTERS
Transcriptional regulation of vascular development
CIRCULATION RESEARCH
Ischemic preconditioning upregulates vascular endothelial growth factor mRNA expression and neovascularization via nuclear translocation of protein kinase C epsilon in the rat ischemic myocardium
CIRCULATION RESEARCH
Therapeutic interventions for enhancing collateral development by administration of growth factors: basic principles, early results and potential hazards
CARDIOVASCULAR RESEARCH
Angiogenic activity of pyruvic acid in in vivo and in vitro angiogenesis models
CANCER RESEARCH
HIF-1 alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis
CANCER RESEARCH
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas - Itsimpact on prognosis and on neoangiogenesis
CANCER
Regulation of vascular endothelial growth factor transcription by endothelial PAS domain protein 1 (EPAS1) and possible involvement of EPAS1 in the angiogenesis of renal cell carcinoma
CANCER
Accumulation of HIF-1 alpha under the influence of nitric oxide
BLOOD
Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells
BIOCHEMICAL PHARMACOLOGY
Identification of genes differentially induced by hypoxia in pancreatic cancer cells
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1 alpha in rasV12 upregulation of VEGF
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Discovery of tissue-specific regulation of erythropoietin expression and applied biochemical study
NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY
Cellular oxygen sensing by mitochondria: old questions, new insight
JOURNAL OF APPLIED PHYSIOLOGY
Historical perspectives of cellular oxygen sensing and responses to hypoxia
JOURNAL OF APPLIED PHYSIOLOGY
HIF-1: mediator of physiological and pathophysiological responses to hypoxia
JOURNAL OF APPLIED PHYSIOLOGY
Role of HIF-1 as a transcription factor involved in embryonic development,cancer progression and apoptosis (review)
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Oxygen regulation of gene expression: A study in opposites
MOLECULAR GENETICS AND METABOLISM
Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment
CLINICAL CANCER RESEARCH
Low oxygen tension during in vitro maturation is beneficial for supportingthe subsequent development of bovine cumulus-oocyte complexes
MOLECULAR REPRODUCTION AND DEVELOPMENT
Excessive concentration of glucose during in vitro maturation impairs the developmental competence of bovine oocytes after in vitro fertilization: Relevance to intracellular reactive oxygen species and glutathione contents
MOLECULAR REPRODUCTION AND DEVELOPMENT
O-2-evoked regulation of HIF-1 alpha and NF-kappa B in perinatal lung epithelium requires glutathione biosynthesis
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Molecular events implicated in brain tumor angiogenesis and invasion
PEDIATRIC NEUROSURGERY
Development of a hypoxia-responsive vector for tumor-specific gene therapy
GENE THERAPY
Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation
EUROPEAN JOURNAL OF CANCER
Microenvironment-induced cancer metastasis
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
The human myoepithelial cell displays a multifaceted anti-angiogenic phenotype
ONCOGENE
Nitric oxide inhibits dioxin action for the stimulation of Cyp1a1 promoteractivity
BIOLOGICAL & PHARMACEUTICAL BULLETIN
Erythropoietin: Multiple physiological functions and regulation of biosynthesis
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Nitric oxide affects the production of reactive oxygen species in hepatomacells: Implications for the process of oxygen sensing
FREE RADICAL BIOLOGY AND MEDICINE
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1 alpha
GENES & DEVELOPMENT
Multiple molecular penumbras after focal cerebral ischemia
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
Physiological oxygen tensions modulate expression of the mdr1b multidrug-resistance gene in primary rat hepatocyte cultures
BIOCHEMICAL JOURNAL
Mechanism of regulation of the hypoxia-inducible factor-l alpha by the vonHippel-Lindau tumor suppressor protein
EMBO JOURNAL
Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer
ANTICANCER RESEARCH
Tissue-specific regulation of erythropoietin production in the murine kidney, brain, and uterus
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Endothelial cell responses to hypoxia: initiation of a cascade of cellularinteractions
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
Adriana and Luisa Castellucci Award Lecture 1999 - Role of oxygen in the regulation of trophoblast gene expression and invasion
PLACENTA
Hypoxic signal transduction in critical illness
CRITICAL CARE MEDICINE
Role of nitric oxide in the pathogenesis of chronic pulmonary hypertension
PHYSIOLOGICAL REVIEWS
Early expression of angiogenesis factors in acute myocardial ischemia and infarction.
NEW ENGLAND JOURNAL OF MEDICINE
Rice in deep water: "How to take heed against a sea of troubles"
NATURWISSENSCHAFTEN
Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The transcription factor EPAS-1/hypoxia-inducible factor 2 alpha plays an important role in vascular remodeling
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Tissue responses to ischemia: local and remote responses for preserving perfusion of ischemic muscle
JOURNAL OF CLINICAL INVESTIGATION
Retinal and choroidal neovascularization
JOURNAL OF CELLULAR PHYSIOLOGY
Accelerated publication - Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
JOURNAL OF BIOLOGICAL CHEMISTRY
Structural determinants for post-transcriptional stabilization of lactate dehydrogenase A mRNA by the protein kinase C signal pathway
JOURNAL OF BIOLOGICAL CHEMISTRY
Protein kinase C-beta and oxygen deprivation - A novel Egr-1-dependent pathway for fibrin deposition in hypoxemic vasculature
JOURNAL OF BIOLOGICAL CHEMISTRY
A conserved mechanism for controlling the translation of beta-F1-ATPase mRNA between the fetal liver and cancer cells
JOURNAL OF BIOLOGICAL CHEMISTRY
ERK activation upon hypoxia: involvement in HIF-1 activation
FEBS LETTERS
Cadmium blocks hypoxia-inducible factor (HIF)-1-mediated response to hypoxia by stimulating the proteasome-dependent degradation of HIF-1 alpha
EUROPEAN JOURNAL OF BIOCHEMISTRY
Identification of hypoxia-responsive messengers expressed in human microvascular endothelial cells using differential display RT-PCR
EUROPEAN JOURNAL OF BIOCHEMISTRY
Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes
CIRCULATION RESEARCH
Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1 alpha/VP16 hybrid transcription factor
CIRCULATION
DNA methylation represses the expression of the human erythropoietin gene by two different mechanisms
BLOOD
Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI3K pathway
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Molecular modeling of the hypoxia-inducible factor-1 (HIF-1)
THEORETICAL CHEMISTRY ACCOUNTS
Hypoxia/hypoxemia-induced activation of the procoagulant pathways and the pathogenesis of ischemia-associated thrombosis
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Characterization of physiologically regulated vectors for the treatment ofischemic disease
HUMAN GENE THERAPY
Differential signaling pathways of HO-1 gene expression in pulmonary and systemic vascular cells
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Oncogenic alterations of metabolism
TRENDS IN BIOCHEMICAL SCIENCES
ARNT2, a transcription factor for brain neuron survival?
EUROPEAN JOURNAL OF NEUROSCIENCE