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La ricerca find articoli where soggetti phrase all words 'HORMONE RECEPTORS' sort by level,fasc_key/DESCEND, pagina_ini_num/ASCEND ha restituito 1563 riferimenti
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    1. Elinson, RP
      Direct development: An alternative way to make a frog

      GENESIS
    2. Toth, P
      Clinical data supporting the importance of vascular LH/hCG receptors of uterine blood vessels

      SEMINARS IN REPRODUCTIVE MEDICINE
    3. Kurtzman, JT; Wilson, H; Rao, CV
      A proposed role for hCC in clinical obstetrics

      SEMINARS IN REPRODUCTIVE MEDICINE
    4. Xu, L; Zerby, D; Huang, Y; Ji, H; Nyanguile, OF; de los Angeles, JE; Kadan, MJ
      A versatile framework for the design of ligand-dependent, transgene-specific transcription factors

      MOLECULAR THERAPY
    5. Blakeman, PJ; Hilton, P; Bulmer, JN
      Cellular proliferation in the female lower urinary tract with reference tooestrogen status

      BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
    6. Mochizuki, K; Suruga, K; Yagi, E; Takase, S; Goda, T
      The expression of PPAR-associated genes is modulated through postnatal development of PPAR subtypes in the small intestine

      BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
    7. Whitacre, DC; Karnas, KJ; Miesfeld, RL
      Analysis of glucocorticoid and androgen receptor gene fusions delineates domains required for transcriptional specificity

      ENDOCRINE
    8. Lonning, PE; Sorlie, T; Perou, CM; Brown, PO; Botstein, D; Borresen-Dale, AL
      Microarrays in primary breast cancer - lessons from chemotherapy studies

      ENDOCRINE-RELATED CANCER
    9. Compagno, V; Di Liegro, I; Cestelli, A; Donatelli, M
      Expression of thyroid hormone receptor isoforms in the hypertrophic heart of spontaneously hypertensive rats

      INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
    10. Zannis, VI; Kan, HY; Kritis, A; Zanni, E; Kardassis, D
      Transcriptional regulation of the human apolipoprotein genes

      FRONTIERS IN BIOSCIENCE
    11. Coleman, KM; Smith, CL
      Intracellular signaling pathways: Nongenomic actions of estrogens and ligand-independent activation of estrogen receptors

      FRONTIERS IN BIOSCIENCE
    12. Synold, TW; Dussault, I; Forman, BM
      The orphan nuclear receptor SXR coordinately regulates drug metabolism andefflux

      NATURE MEDICINE
    13. Shi, YH; Koh, JT
      Selective regulation of gene expression by an orthogonal estrogen receptor-ligand pair created by polar-group exchange

      CHEMISTRY & BIOLOGY
    14. Ferrero-Pous, M; Trassard, M; Le Doussal, V; Hacene, K; Tubiana-Hulin, M; Spyratos, F
      Comparison of enzyme immunoassay and immunohistochemical measurements of estrogen and progesterone receptors in breast cancer patients

      APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
    15. Lenhard, JM
      PPAR gamma/RXR as a molecular target for diabetes

      RECEPTORS & CHANNELS
    16. Steinmetz, ACU; Renaud, JP; Moras, D
      Binding of ligands and activation of transcription by nuclear receptors

      ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE
    17. Koibuchi, N; Yamaoka, S; Chin, WW
      Effect of altered thyroid status on neurotrophin gene expression during postnatal development of the mouse cerebellum

      THYROID
    18. Leibovich, H; Raver, N; Herman, A; Gregoraszczuk, EL; Gootwine, E; Gertler, A
      Large-scale preparation of recombinant ovine prolactin and determination of its in vitro and in vivo activity

      PROTEIN EXPRESSION AND PURIFICATION
    19. Koritschoner, NP; Madruga, J; Knespel, S; Blendinger, G; Anzinger, B; Otto, A; Zenke, M; Bartunek, P
      The nuclear orphan receptor TR4 promotes proliferation of myeloid progenitor cells

      CELL GROWTH & DIFFERENTIATION
    20. Mussig, C; Altmann, T
      Brassinosteroid signaling in plants

      TRENDS IN ENDOCRINOLOGY AND METABOLISM
    21. Sambroni, E; Gutieres, S; Cauty, C; Guiguen, Y; Breton, B; Lareyre, JJ
      Type II iodothyronine deiodinase is preferentially expressed in rainbow trout (Oncorhynchus mykiss) liver and gonads

      MOLECULAR REPRODUCTION AND DEVELOPMENT
    22. Ratajczak, T
      Protein coregulators that mediate estrogen receptor function

      REPRODUCTION FERTILITY AND DEVELOPMENT
    23. Onishi, K; Kato, MV; Bai, F; Sakai, T
      SMRT as a T3SF-binding protein

      INTERNATIONAL JOURNAL OF ONCOLOGY
    24. Pike, ACW; Brzozowski, AM; Walton, J; Hubbard, RE; Thorsell, AG; Li, YL; Gustafsson, JA; Carlquist, M
      Structural insights into the mode of action of a pure antiestrogen

      STRUCTURE
    25. Schwechheimer, C; Deng, XW
      COP9 signalosome revisited: a novel mediator of protein degradation

      TRENDS IN CELL BIOLOGY
    26. Tremblay, A; Vincent, G
      Contribution of steroid receptor coactivator-1 and CREB binding protein inligand-independent activity of estrogen receptor beta

      JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
    27. Ringberg, A; Anagnostaki, L; Anderson, H; Idvall, I; Ferno, M
      Cell biological factors in ductal carcinoma in situ (DCIS) of the breast-relationship to ipsilateral local recurrence and histopathological characteristics

      EUROPEAN JOURNAL OF CANCER
    28. Hepp, R; Grant, NJ; Espliguero, G; Aunis, D; Sarlieve, LL; Rodrigues-Pena, A; Langley, K
      Adrenal gland SNAP-25 expression is altered in thyroid hormone receptor knockout mice

      NEUROREPORT
    29. Torra, IP; Chinetti, G; Duval, C; Fruchart, JC; Staels, B
      Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice

      CURRENT OPINION IN LIPIDOLOGY
    30. Auger, AP; Meredith, JM; Snyder, GL; Blaustein, JD
      Oestradiol increases phosphorylation of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in female rat brain

      JOURNAL OF NEUROENDOCRINOLOGY
    31. Wells, T; Houston, PA
      Skeletal growth acceleration with growth hormone secretagogues in transgenic growth retarded rats: Pattern-dependent effects and mechanisms of desensitization

      JOURNAL OF NEUROENDOCRINOLOGY
    32. Thompson, PD; Remus, LS; Hsieh, JC; Jurutka, PW; Whitfield, GK; Galligan, MA; Dominguez, CE; Haussler, CA; Haussler, MR
      Distinct retinoid X receptor activation function-2 residues mediate transactivation in homodimeric and vitamin D receptor heterodimeric contexts

      JOURNAL OF MOLECULAR ENDOCRINOLOGY
    33. Bjornstrom, L; Kilic, E; Norman, M; Parker, MG; Sjoberg, M
      Cross-talk between Stat5b and estrogen receptor-alpha and -beta in mammaryepithelial cells

      JOURNAL OF MOLECULAR ENDOCRINOLOGY
    34. Salazar, EL; Sojo-Aranda, I; Lopez, R; Salcedo, M
      The evidence for an etiological relationship between oral contraceptive use and dysplastic change in cervical tissue

      GYNECOLOGICAL ENDOCRINOLOGY
    35. Li, M; Chiba, H; Warot, X; Messaddeq, N; Gerard, C; Chambon, P; Metzger, D
      RXR alpha ablation in skin keratinocytes results in alopecia and epidermalalterations

      DEVELOPMENT
    36. Hauptmann, S; Dietel, M
      Serous tumors of low malignant potential of the ovary-molecular pathology:part 2

      VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
    37. Nagpal, S; Lu, HF; Boehm, MF
      Vitamin D analogs: Mechanism of action and therapeutic applications

      CURRENT MEDICINAL CHEMISTRY
    38. Shi, YH; Downes, M; Xie, W; Kao, HY; Ordentlich, P; Tsai, CC; Hon, M; Evans, RM
      Sharp, an inducible cofactor that integrates nuclear receptor repression and activation

      GENES & DEVELOPMENT
    39. Handschin, C; Podvinec, M; Stockli, J; Hoffmann, K; Meyer, UA
      Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, andpregnane X receptor, from birds to humans

      MOLECULAR ENDOCRINOLOGY
    40. Yudt, MR; Cidlowski, JA
      Molecular identification and characterization of A and B forms of the glucocorticoid receptor

      MOLECULAR ENDOCRINOLOGY
    41. Wood, JR; Likhite, VS; Loven, MA; Nardulli, AM
      Allosteric modulation of estrogen receptor conformation by different estrogen response elements

      MOLECULAR ENDOCRINOLOGY
    42. Zilliacus, J; Holter, E; Wakui, H; Tazawa, H; Treuter, E; Gustafsson, JA
      Regulation of glucocorticoid receptor activity by 14-3-3-dependent intracellular relocalization of the corepressor RIP140

      MOLECULAR ENDOCRINOLOGY
    43. Wissink, S; van der Burg, B; Katzenellenbogen, BS; van der Saag, PT
      Synergistic activation of the serotonin-1A receptor by nuclear factor-kappa B and estrogen

      MOLECULAR ENDOCRINOLOGY
    44. Schmidt, P; Holsboer, F; Spengler, D
      beta(2)-Adrenergic receptors potentiate glucocorticoid receptor transactivation via G protein beta gamma-subunits and the phosphoinositide 3-kinase pathway

      MOLECULAR ENDOCRINOLOGY
    45. Giannoukos, G; Szapary, D; Smith, CL; Meeker, JEW; Simons, SS
      New antiprogestins with partial agonist activity: Potential selective progesterone receptor modulators (SPRMs) and probes for receptor- and coregulator-induced changes in progesterone receptor induction properties

      MOLECULAR ENDOCRINOLOGY
    46. Metivier, R; Penot, G; Flouriot, G; Pakdel, F
      Synergism between ER alpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: Requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminaldomains

      MOLECULAR ENDOCRINOLOGY
    47. Barbulescu, K; Geserick, C; Schuttke, I; Schleuning, WD; Haendler, B
      New androgen response elements in the murine Pem promoter mediate selective transactivation

      MOLECULAR ENDOCRINOLOGY
    48. Nio, Y; Iguchi, C; Yamasawa, K; Sasaki, S; Takamura, M; Toga, T; Dong, M; Itakura, M; Tamura, K
      Apoptosis and expression of Bcl-2 and Bax proteins in invasive ductal carcinoma of the pancreas

      PANCREAS
    49. Fischle, W; Kiermer, V; Dequiedt, F; Verdin, E
      The emerging role of class II histone deacetylases

      BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE
    50. Garcia-Reyero, N; Grau, E; Castillo, M; De Alda, MJL; Barcelo, D; Pina, B
      Monitoring of endocrine disruptors in surface waters by the yeast recombinant assay

      ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
    51. Heikenwalder, MF; Koritschoner, NP; Pajer, P; Chaboissier, MC; Kurz, SM; Briegel, KJ; Bartunek, P; Zenke, M
      Molecular cloning, expression and regulation of the avian tubby-like protein 1 (tulp1) gene

      GENE
    52. Gonzalez-Aguero, G; Ondarza, R; Gamboa-Dominguez, A; Cerbon, MA; Camacho-Arroyo, I
      Progesterone receptor isoforms expression pattern in human astrocytomas

      BRAIN RESEARCH BULLETIN
    53. Rose, DP; Royak-Schaler, R
      Tumor biology and prognosis in black breast cancer patients: A review

      CANCER DETECTION AND PREVENTION
    54. Lara, PN; Gandara, DR; Longmate, J; Gumerlock, PH; Martin, DHML; Edelman, J; Gandour-Edwards, R; Mack, PC; Israel, V; Raschko, J; Frankel, P; Perez, EA; Lenz, HJ; Doroshow, JH
      Activity of high-dose toremifene plus cisplatin in platinum-treated nonsmall-cell lung cancer: a phase II California Cancer Consortium Trial

      CANCER CHEMOTHERAPY AND PHARMACOLOGY
    55. Barnes, DM; Hanby, AM
      Oestrogen and progesterone receptors in breast cancer: past, present and future

      HISTOPATHOLOGY
    56. Klinge, CM
      Estrogen receptor interaction with estrogen response elements

      NUCLEIC ACIDS RESEARCH
    57. Yoo, KY; Tajima, K; Park, SK; Kang, D; Kim, SU; Hirose, K; Takeuchi, T; Miura, S
      Postmenopausal obesity as a breast cancer risk factor according to estrogen and progesterone receptor status (Japan)

      CANCER LETTERS
    58. Muyan, M; Yi, P; Sathya, G; Willmert, LJ; Driscoll, MD; Hilf, R; Bambara, RA
      Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    59. Inoue, T; Akahira, J; Takeyama, J; Suzuki, T; Darnel, AD; Kaneko, C; Kurokawa, Y; Satomi, S; Sasano, H
      Spatial and topological distribution of progesterone receptor A and B isoforms during human development

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    60. Loven, MA; Wood, JR; Nardulli, AM
      Interaction of estrogen receptors alpha and beta with estrogen response elements

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    61. Ozers, MS; Hill, JJ; Ervin, K; Royer, CA; Gorski, J
      The dissociation rate of estrogen receptor alpha from the consensus estrogen response element

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    62. Haendler, B; Schuttke, I; Schleuning, WD
      Androgen receptor signalling: comparative analysis of androgen response elements and implication of heat-shock protein 90 and 14-3-3 eta

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    63. Lizcano, F; Koibuchi, N; Fukuda, H; Dangond, F; Chin, WW
      Cell type-specific roles of histone deacetylase in TR ligand-independent transcriptional repression

      MOLECULAR AND CELLULAR ENDOCRINOLOGY
    64. Vidal, S; Cameselle-Teijeiro, J; Horvath, E; Kovacs, K; Bartke, A
      Effect of protracted estrogen administration on the thyroid of Ames dwarf mice

      CELL AND TISSUE RESEARCH
    65. Eder, IE; Culig, Z; Putz, T; Nessler-Menardi, C; Bartsch, G; Klocker, H
      Molecular biology of the androgen receptor: From molecular understanding to the clinic

      EUROPEAN UROLOGY
    66. Hermann, B; Vollmer, I; Holsboer, F; Rupprecht, R
      Antidepressants do not modulate estrogen receptor alpha-mediated gene expression

      JOURNAL OF NEURAL TRANSMISSION
    67. Zhou, YY; Gross, W; Hong, SH; Privalsky, ML
      The SMRT corepressor is a target of phosphorylation by protein kinase CK2 (casein kinase II)

      MOLECULAR AND CELLULAR BIOCHEMISTRY
    68. Idvall, I; Andersson, C; Fallenius, G; Ingvar, C; Ringberg, A; Strand, C; Akerman, M; Ferno, M
      Histopathological and cell biological factors of ductal carcinoma in situ before and after the introduction of mammographic screening

      ACTA ONCOLOGICA
    69. Chan, W; Wang, M; Martin, RJ; Trachtman, H; Hisano, S; Chan, JCM
      mRNA expression for insulin-like growth factor 1, receptors of growth hormone and IGF-1 and transforming growth factor-beta in the kidney and liver of Zucker rats

      NUTRITION RESEARCH
    70. Suzuki, T; Kinoshita, Y; Tachibana, M; Matsushima, Y; Kobayashi, Y; Adachi, W; Sotozono, C; Kinoshita, S
      Expression of sex steroid hormone receptors in human cornea

      CURRENT EYE RESEARCH
    71. Felinski, EA; Kim, J; Lu, JF; Quinn, PG
      Recruitment of an RNA polymerase II complex is mediated by the constitutive activation domain in CREB, independently of CREB phosphorylation

      MOLECULAR AND CELLULAR BIOLOGY
    72. Savory, JGA; Prefontaine, GG; Lamprecht, C; Liao, MM; Walther, RF; Lefebvre, YA; Hache, RJG
      Glucocorticoid receptor homodimers and glucocorticoid-mineralcorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfaces

      MOLECULAR AND CELLULAR BIOLOGY
    73. Asahara, H; Santoso, B; Guzman, E; Du, KY; Cole, PA; Davidson, I; Montminy, M
      Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB

      MOLECULAR AND CELLULAR BIOLOGY
    74. Hong, SH; Yang, ZH; Privalsky, ML
      Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with its transcription factor partners, including the PML-retinoic acidreceptor alpha oncoprotein found in human acute promyelocytic leukemia

      MOLECULAR AND CELLULAR BIOLOGY
    75. Guenther, MG; Barak, O; Lazar, MA
      The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

      MOLECULAR AND CELLULAR BIOLOGY
    76. Osburn, DL; Shao, G; Seidel, HM; Schulman, IG
      Ligand-dependent degradation of retinoid X receptors does not require transcriptional activity or coactivator interactions

      MOLECULAR AND CELLULAR BIOLOGY
    77. Stenoien, DL; Nye, AC; Mancini, MG; Patel, K; Dutertre, M; O'Malley, BW; Smith, CL; Belmont, AS; Mancini, MA
      Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor a-coactivator complexes in living cells

      MOLECULAR AND CELLULAR BIOLOGY
    78. Schlegel, A; Wang, CG; Pestell, RG; Lisanti, MP
      Ligand-independent activation of oestrogen receptor alpha by caveolin-1

      BIOCHEMICAL JOURNAL
    79. Hawtin, SR; Davies, ARL; Matthews, G; Wheatley, M
      Identification of the glycosylation sites utilized on the V-1a vasopressinreceptor and assessment of their role in receptor signalling and expression

      BIOCHEMICAL JOURNAL
    80. Haelens, A; Verrijdt, G; Callewaert, L; Peeters, B; Rombauts, W; Claessens, F
      Androgen-receptor-specific DNA binding to an element in the first exon of the human secretory component gene

      BIOCHEMICAL JOURNAL
    81. Kovacs, P; Csaba, G
      Effect of quinacrine treatment on the activity of acid hydrolases (phosphatase, N-acetyl-beta-glucosaminidase, glucosidase, galactosidase and esterase) in Tetrahymena

      CELL BIOCHEMISTRY AND FUNCTION
    82. Kovacs, P; Pinter, M
      Effects of phosphoprotein phosphatase inhibitors (phenylarsine oxide and cantharidin) on Tetrahymena

      CELL BIOCHEMISTRY AND FUNCTION
    83. Castoria, G; Migliaccio, A; Bilancio, A; Di Domenico, M; de Falco, A; Lombardi, M; Fiorentino, R; Varricchio, L; Barone, MV; Auricchio, F
      PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

      EMBO JOURNAL
    84. Saint-Blancard, P; Simon, F; Jancovici, R; Vaylet, F; L'Her, P; Le Vagueresse, R
      Unusual pulmonary nodules

      ANNALES DE PATHOLOGIE
    85. Ishunina, TA; Swaab, DF
      Increased expression of estrogen receptor alpha and beta in the nucleus basalis of Meynert in Alzheimer's disease

      NEUROBIOLOGY OF AGING
    86. De Miguel, MP; Marino, JM; Gonzalez-Peramato, P; Nistal, M; Regadera, J
      Epididymal growth and differentiation are altered in human cryptorchidism

      JOURNAL OF ANDROLOGY
    87. Clement, F; Monniaux, D; Stark, J; Hardy, K; Thalabard, JC; Franks, S; Claude, D
      Mathematical model of FSH-induced cAMP production in ovarian follicles

      AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
    88. Hafner, I; Schoon, HA; Schoon, D; Aupperle, H
      Disorders of differentiation in the equine endometrium - light microscopicand immunohistological studies

      PFERDEHEILKUNDE
    89. Kawata, M; Matsuda, K; Nishi, M; Ogawa, H; Ochiai, I
      Intracellular dynamics of steroid hormone receptor

      NEUROSCIENCE RESEARCH
    90. Lundholt, BK; Briand, P; Lykkesfeldt, AE
      Growth inhibition and growth stimulation by estradiol of estrogen receptortransfected human breast epithelial cell lines involve different pathways

      BREAST CANCER RESEARCH AND TREATMENT
    91. Smith, FB; del Puerto, C; Sagerman, P
      Relationship of estrogen and progesterone receptor protein levels in carcinomatous and adjacent non-neoplastic epithelium of the breast: A histopathologic and image cytometric study

      BREAST CANCER RESEARCH AND TREATMENT
    92. Fantappie, MR; Freebern, WJ; Osman, A; LaDuca, J; Niles, EG; LoVerde, PT
      Evaluation of Schistosoma mansoni retinoid X receptor (SmRXR1 and SmRXR2) activity and tissue distribution

      MOLECULAR AND BIOCHEMICAL PARASITOLOGY
    93. Ravi, M; Hopfinger, AJ; Hormann, RE; Dinan, L
      4D-QSAR analysis of a set of ecdysteroids and a comparison to CoMFA modeling

      JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
    94. Kaltreider, RC; Davis, AM; Lariviere, JP; Hamilton, JW
      Arsenic alters the function of the glucocorticoid receptor as a transcription factor

      ENVIRONMENTAL HEALTH PERSPECTIVES
    95. Safe, S
      Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions

      VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 62
    96. Wallberg, AE; Wright, A; Gustafsson, JA
      Chromatin-remodeling complexes involved in gene activation by the glucocorticoid receptor

      VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 60
    97. Hager, GL
      Understanding nuclear receptor function: From DNA to chromatin to the interphase nucleus

      PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 66
    98. Pettersson, K; Gustafsson, JA
      Role of estrogen receptor beta in estrogen action

      ANNUAL REVIEW OF PHYSIOLOGY
    99. Moller, DE; Greene, DA
      Peroxisome proliferator-activated receptor (PPAR)gamma agonists for diabetes

      ADVANCES IN PROTEIN CHEMISTRY, VOL 56
    100. Csaba, G; Inczefi-Gonda, A
      Similarities and dissimilarities of newborn and adolescent rats in the binding capacity of thymic glucocorticoid receptors

      MECHANISMS OF AGEING AND DEVELOPMENT


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/21 alle ore 10:38:19