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Molecular genetics of acute myeloid leukaemia
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY
A functionally active RAR alpha nuclear receptor is expressed in retinoic acid non responsive early myeloblastic cell lines
CELL DEATH AND DIFFERENTIATION
Molecular genetics of Rett syndrome and clinical spectrum of MECP2 mutations
CURRENT OPINION IN NEUROLOGY
Role of PML and PML-RAR alpha in Mad-mediated transcriptional repression
MOLECULAR CELL
The role of DNA methyltransferase 1 in growth control
FRONTIERS IN BIOSCIENCE
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
NATURE GENETICS
Kaiso, a new protein of the BTB/POZ family, specifically binds to methylated DNA sequences
RUSSIAN JOURNAL OF GENETICS
Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice
ONCOGENE
Transcriptional regulation in acute promyelocytic leukemia
ONCOGENE
Common themes in the pathogenesis of acute myeloid leukemia
ONCOGENE
Rb-mediated chromatin structure regulation and transcriptional repression
ONCOGENE
DNA methylation, methyltransferases, and cancer
ONCOGENE
DNA methylation, chromatin inheritance, and cancer
ONCOGENE
Methyl CpG binding proteins: coupling chromatin architecture to gene regulation
ONCOGENE
The negative regulator Opi1 of phospholipid biosynthesis in yeast contactsthe pleiotropic repressor Sin3 and the transcriptional activator Ino2
MOLECULAR MICROBIOLOGY
Methylated cytosine and the brain: A new base for neuroscience
NEURON
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
GENES & DEVELOPMENT
Lsh, a member of the SNF2 family, is required for genome-wide methylation
GENES & DEVELOPMENT
Transcriptional repression: the long and the short of it
GENES & DEVELOPMENT
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor
GENES & DEVELOPMENT
The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression
MOLECULAR ENDOCRINOLOGY
CpG island of rat sphingosine kinase-1 gene: tissue-dependent DNA methylation status and multiple alternative first exons
GENOMICS
Genetic lesions and perturbation of chromatin architecture: A road to celltransformation
JOURNAL OF CELLULAR BIOCHEMISTRY
Toti-/pluripotential stem cells and epigenetic modifications
CELL STRUCTURE AND FUNCTION
Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3
GENE
Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription
NUCLEIC ACIDS RESEARCH
Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer
DIFFERENTIATION
Genomic organization and refined mapping of the human nuclear corepressor 2 (NCOR2)/silencing mediator of retinoid and thyroid hormone receptor (SMRT) gene on chromosome 12q24.3
CYTOGENETICS AND CELL GENETICS
Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satelliteregions during human hepatocarcinogenesis
HEPATOLOGY
PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors
MOLECULAR AND CELLULAR BIOLOGY
CpG binding protein is crucial for early embryonic development
MOLECULAR AND CELLULAR BIOLOGY
Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex
MOLECULAR AND CELLULAR BIOLOGY
HERP, a novel heterodimer partner of HES/E(spl) in notch signaling
MOLECULAR AND CELLULAR BIOLOGY
Embryonic but not postnatal reexpression of hepatocyte nuclear factor 1 alpha (HNF1 alpha) can reactivate the silent phenylalanine hydroxylase gene in HNF1 alpha-deficient hepatocytes
MOLECULAR AND CELLULAR BIOLOGY
Oligomerization of ETO is obligatory for corepressor interaction
MOLECULAR AND CELLULAR BIOLOGY
Methyl CpG-binding transcriptional proteins and repression
BIOESSAYS
Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos
EMBO JOURNAL
Functional interaction of STAT5 and nuclear receptor co-repressor SMRT: implications in negative regulation of STAT5-dependent transcription
EMBO JOURNAL
Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA
CELL
Signal transduction pathways and the modification of chromatin structure
PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 65
Retinoblastoma protein partners
ADVANCES IN CANCER RESEARCH, VOL 82
Acute promyelocytic leukemia with a PLZF-RAR alpha fusion protein
SEMINARS IN HEMATOLOGY
Effects of the acute myeloid leukemia-associated fusion proteins on nuclear architecture
SEMINARS IN HEMATOLOGY
Physiological and molecular basis of thyroid hormone action
PHYSIOLOGICAL REVIEWS
Nuclear hormone receptors and gene expression
PHYSIOLOGICAL REVIEWS
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The role of epigenetic modifications in retinoic acid receptor beta 2 geneexpression in human prostate cancers
LABORATORY INVESTIGATION
Methylation and colorectal cancer
JOURNAL OF PATHOLOGY
Role of MED1 (MBD4) gene in DNA repair and human cancer
JOURNAL OF CELLULAR PHYSIOLOGY
PML-RAR alpha alleviates the transcriptional repression mediated by tumor suppressor Rb
JOURNAL OF BIOLOGICAL CHEMISTRY
Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2
JOURNAL OF BIOLOGICAL CHEMISTRY
Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells
JOURNAL OF BIOLOGICAL CHEMISTRY
The ski protein family is required for MeCP2-mediated transcriptional repression
JOURNAL OF BIOLOGICAL CHEMISTRY
Silencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a transcriptional repressor
JOURNAL OF BIOLOGICAL CHEMISTRY
DNA demethylation reactivates a subset of imprinted genes in uniparental mouse embryonic fibroblasts
JOURNAL OF BIOLOGICAL CHEMISTRY
Methyl-CpG-binding proteins - Targeting specific gene repression
EUROPEAN JOURNAL OF BIOCHEMISTRY
Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia
CANCER RESEARCH
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells
CANCER RESEARCH
Loss of expression of HDAC-recruiting methyl-CpG-binding domain proteins in human cancer
BRITISH JOURNAL OF CANCER
The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling
BLOOD
GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells
AMERICAN JOURNAL OF PATHOLOGY
DNA methylation in health and disease
NATURE REVIEWS GENETICS
Identification of a CpG island in the human LRP-2 gene and analysis of itsmethylation status in parathyroid adenomas
BIOLOGICAL CHEMISTRY
MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase
GENES TO CELLS
Oligomerization of RAR and AML1 transcription factors as a novel mechanismof oncogenic activation
MOLECULAR CELL
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
NATURE GENETICS
DNA methylation and silencing of gene expression
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Transcriptional repression by nuclear hormone receptors
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Rett syndrome: a surprising result of mutation in MECP2
HUMAN MOLECULAR GENETICS
The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR
ONCOGENE
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta 2 promoter in breast cancer cells
ONCOGENE
DNA methylation and gastrointestinal malignancies: functional consequencesand clinical implications
JOURNAL OF GASTROENTEROLOGY
Co-repressors 2000
FASEB JOURNAL
Regional methylation of the 5 ' end CpG island of BRCA1 is associated withreduced gene expression in human somatic cells
FASEB JOURNAL
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness
GENES & DEVELOPMENT
De novo nucleosome assembly: new pieces in an old puzzle
GENES & DEVELOPMENT
H19 and Igf2 monoallelic expression is regulated in two distinct ways by ashared cis acting regulatory region upstream of H19
GENES & DEVELOPMENT
New agents for acute myelogenous leukemia
LEUKEMIA
Differentiation therapy in acute myelogenous leukemia (non-APL)
LEUKEMIA
Chromatin plasticity, control of gene expression and human disease
M S-MEDECINE SCIENCES
Tumor metastasis-associated human MTA1 gene: Its deduced protein sequence,localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotides
JOURNAL OF CELLULAR BIOCHEMISTRY
DNA methylation, nuclear structure, gene expression and cancer
JOURNAL OF CELLULAR BIOCHEMISTRY
MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery
NUCLEIC ACIDS RESEARCH
The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein
MOLECULAR AND CELLULAR BIOLOGY
Active repression of methylated genes by the chromosomal protein MBD1
MOLECULAR AND CELLULAR BIOLOGY
Transcriptional repression by Drosophila methyl-CpG-binding proteins
MOLECULAR AND CELLULAR BIOLOGY
Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1
MOLECULAR AND CELLULAR BIOLOGY
Characterization of carrot nuclear proteins that exhibit specific binding affinity towards conventional and non-conventional DNA methylation
PLANT MOLECULAR BIOLOGY
Transcriptional gene silencing mutants
PLANT MOLECULAR BIOLOGY
Transgene silencing by the host genome defense: implications for the evolution of epigenetic control mechanisms in plants and vertebrates
PLANT MOLECULAR BIOLOGY
Novel therapeutic agents for the treatment of myelodysplastic syndromes
SEMINARS IN ONCOLOGY
Solution structure of the interacting domains of the Mad-Sin3 complex: Implications for recruitment of a chromatin-modifying complex
CELL
Mammalian methyltransferases and methyl-CpG-binding domains: Proteins involved in DNA methylation
DNA METHYLATION AND CANCER
Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RAR alpha and PLZF-RAR alpha oncoproteins
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Gilbert's conjecture: The search for DNA (cytosine-5) demethylases and theemergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases
JOURNAL OF MOLECULAR BIOLOGY
Short TpA-rich segments of the zeta-eta region induce DNA methylation in Neurospora crassa
JOURNAL OF MOLECULAR BIOLOGY
Chromatin modification and disease
JOURNAL OF MEDICAL GENETICS
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1
JOURNAL OF BIOLOGICAL CHEMISTRY
Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long-distance gene regulation
JOURNAL OF BIOCHEMISTRY
Notch signaling: From the outside in
DEVELOPMENTAL BIOLOGY