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Design of nonpeptides from peptide ligands for peptide receptors
G PROTEIN PATHWAYS, PT A, RECEPTORS
Regulation of G protein-coupled receptor kinase 2
G PROTEIN PATHWAYS, PT A, RECEPTORS
Three-dimensional structure of the large cytoplasmic H-4-H-5 loop of Na+/K+-ATPase deduced by restraint-based comparative modeling shows only one ATPbinding site
JOURNAL OF MOLECULAR MODELING
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer
NATURE IMMUNOLOGY
Insecticidal and binding activities of N3-substituted imidacloprid derivatives against the housefly Musca domestica and the alpha-bungarotoxin binding sites of nicotinic acetylcholine receptors
PEST MANAGEMENT SCIENCE
Toxicity and nicotinic acetylcholine receptor interaction of imidacloprid and its metabolites in Apis mellifera (Hymenoptera : Apidae)
PEST MANAGEMENT SCIENCE
Structure and diversity of insect nicotinic acetylcholine receptors
PEST MANAGEMENT SCIENCE
Synthesis and DNA cleavage activity of a novel bleomycin A(5) glycoconjugate
ORGANIC LETTERS
Comparison of block among cloned cardiac potassium channels by non-antiarrhythmic drugs
EUROPEAN HEART JOURNAL SUPPLEMENTS
Towards a modular approach for heparin synthesis
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Potential roles of decidual prolactin in early pregnancy
REPRODUCTION
The activation of fibroblast growth factors by heparin: Synthesis, structure, and biological activity of heparin-like oligosaccharides
CHEMBIOCHEM
Synthesis of conformationally locked carbohydrates: A skew-boat conformation of L-iduronic acid governs the antithrombotic activity of heparin
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Indoloparacyclophanes: Synthesis and dopamine receptor binding of a novel arylbioisostere
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Analysis of the RGD sequence in protein structures: comparison to the conformations of the RGDW and (D)RGDW peptides determined by molecular dynamicssimulations
THEORETICAL CHEMISTRY ACCOUNTS
On the existence of cytokines in invertebrates
CELLULAR AND MOLECULAR LIFE SCIENCES
Nitrate and nitrite transport in bacteria
CELLULAR AND MOLECULAR LIFE SCIENCES
Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain
JOURNAL OF PEPTIDE RESEARCH
Nonhost resistance to Phytophthora: novel prospects for a classical problem
CURRENT OPINION IN PLANT BIOLOGY
Lead compounds discovered from libraries
CURRENT OPINION IN CHEMICAL BIOLOGY
The IGF system in thyroid cancer: new concepts
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY
Antibody libraries in drug and target discovery
DRUG DISCOVERY TODAY
Dopamine D-2/D-3-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics
MOLECULAR PSYCHIATRY
Sequence-specific interaction between HIV-1 matrix protein and viral genomic RNA revealed by in vitro genetic selection
RNA-A PUBLICATION OF THE RNA SOCIETY
CCK2 receptor antagonists
EXPERT OPINION ON THERAPEUTIC PATENTS
Inhibitors of p56(lck): assessing their potential as tools for manipulating T-lymphocyte activation
EXPERT OPINION ON THERAPEUTIC PATENTS
Different adhesins for type IV collagen on Candida albicans: identification of a lectin-like adhesin recognizing the 7S(IV) domain
MICROBIOLOGY-SGM
Enhanced expression of basement-membrane-type heparan sulfate proteoglycanin tumor fibro-myxoid stroma of intrahepatic cholangiocarcinoma
PATHOLOGY INTERNATIONAL
Pathogenesis of beta(2)-microglobulin amyloidosis
PATHOLOGY INTERNATIONAL
Stimulatory and inhibitory signals originating from the macrophage Fc gamma receptors
MICROBES AND INFECTION
The new generation of GABA enhancers - Potential in the treatment of epilepsy
CNS DRUGS
Activation of Fc epsilon RI-positive eosinophils in bullous pemphigoid
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions
MOLECULAR CELL
Cellular uptake of taurine by lactating porcine mammary tissue
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
Development and evaluation of high throughput functional assay methods forhERG potassium channel
JOURNAL OF BIOMOLECULAR SCREENING
Fondaparinux sodium: A selective inhibitor of factor Xa
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
Expression levels of the nerve growth factor receptors TrkA and p75 in effusions and solid tumors of serous ovarian carcinoma patients
CLINICAL CANCER RESEARCH
New conformationally homogeneous beta-turn antagonists of the human B-2 kinin receptor
JOURNAL OF PEPTIDE SCIENCE
Pharmacokinetic analysis of lectin-dependent biodistribution of fucosylated bovine serum albumin: A possible carrier for Kupffer cells
JOURNAL OF DRUG TARGETING
Characterization, stability and in-vivo distribution of asialofetuin glycopeptide incorporating DSPC/CHOL liposomes prepared by mild cholate incubation
JOURNAL OF DRUG TARGETING
Reconstitution of human 5-hydroxytryptamine(5A) receptor-G protein coupling in E-coli and Sf9 cell membranes with membranes from Sf9 cells expressingmammalian G proteins
RECEPTORS & CHANNELS
Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): Mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor
HUMAN MUTATION
Congenital insensitivity to pain with anhidrosis (CIPA): Novel mutations of the TRK4 (NTRK1) gene, a putative uniparental disomy, and a linkage of the mutant TRKA and PKLR genes in a family with CIPA and pyruvate kinase deficiency
HUMAN MUTATION
Model of the BzR binding site: Correlation of data from site-directed mutagenesis and the pharmacophore/receptor model
MEDICINAL CHEMISTRY RESEARCH
Potentials and pitfalls using high affinity radioligands in PET and SPET determinations on regional drug induced D2 receptor occupancy - A simulationstudy based on experimental data
NEUROIMAGE
Production of correctly folded Fab antibody fragment in the cytoplasm of Escherichia coli trxB gor mutants via the coexpression of molecular chaperones
PROTEIN EXPRESSION AND PURIFICATION
Expression and characterization of recombinant human antithrombin III in Pichia pastoris
PROTEIN EXPRESSION AND PURIFICATION
Neurotrophins and neurotrophin receptors in human lung cancer
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Inhibition of immunologic and nonimmunologic stimulation-mediated anaphylactic reactions by water extract of white eggplant (Solanum melongena)
PHARMACOLOGICAL RESEARCH
Gonadotropin-releasing hormone antagonist: how good is the new hope?
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
Preclinical and clinical data with bispecific antibodies recruiting myeloid effector cells for tumor therapy
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
A harpin binding site in tobacco plasma membranes mediates activation of the pathogenesis-related gene HIN1 independent of extracellular calcium but dependent on mitogen-activated protein kinase activity
PLANT CELL
Surfactant protein A and lipid are internalized via the coated-pit pathwayby type II pneumocytes
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
Binding of phage-displayed HIV-1 Tat to TAR RNA in the presence of cyclin T1
JOURNAL OF BIOMEDICAL SCIENCE
Detection of mRNA expression of gonadotropin-releasing hormone and its receptor in normal and neoplastic rat prostates
INTERNATIONAL JOURNAL OF ONCOLOGY
Allergy to dermatophagoides in a group of Spanish gypsies: Genetic restrictions
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Fc epsilon RI-mediated activation of transcription factors in antigen-presenting coils
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
A comparison of Fc epsilon RI-mediated RANTES release from human plateletsbetween allergic patients and healthy individuals
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Regulation of surface Fc epsilon RI expression an human eosinophils by IL-4 and IgE
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Unexpected functions of Fc epsilon RI on antigen-presenting cells
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Studies of different aspects of the pole of protein kinase C in mast cells
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
Differential effects of vascular endothelial growth factor-C and placentalgrowth factor-1 on the hydraulic conductivity of frog mesenteric capillaries
JOURNAL OF VASCULAR RESEARCH
Expression and characterization of a recombinant Fab fragment derived froman anti-human alpha-fetoprotein monoclonal antibody
MOLECULES AND CELLS
Induction of alpha 1-acid glycoprotein mRNA by cytokines and differentiation in human colon carcinoma cell
MOLECULES AND CELLS
Impaired glutamate uptake in the R6 Huntington's disease transgenic mice
NEUROBIOLOGY OF DISEASE
[C-11]Raclopride binding was reduced in vivo by sigma(1) receptor ligand SA4503 in the mouse brain, while [C-11]SA4503 binding was not by raclopride
NUCLEAR MEDICINE AND BIOLOGY
Molecular modeling, structure-activity relationships and functional antagonism studies of 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketones as a novel class of dopamine transporter inhibitors
BIOORGANIC & MEDICINAL CHEMISTRY
Synthesis of tropane and nortropane analogues with phenyl substitutions asserotonin transporter ligands
BIOORGANIC & MEDICINAL CHEMISTRY
N-terminal carboxyl and tetrazole-containing amides as adjuvants to Grb2 SH2 domain ligand binding
BIOORGANIC & MEDICINAL CHEMISTRY
Synthesis and pharmacological evaluation of imidazoline sites I-1 and I-2 selective ligands
BIOORGANIC & MEDICINAL CHEMISTRY
Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex
BIOORGANIC & MEDICINAL CHEMISTRY
6-(4-benzylpiperazin-1-yl)benzodioxanes as selective ligands at cloned primate dopamine D-4 receptors
BIOORGANIC & MEDICINAL CHEMISTRY
Synthesis of galactosyl compounds for targeted gene delivery
BIOORGANIC & MEDICINAL CHEMISTRY
The role of backbone conformation in deltorphin II binding: A QSAR study of new analogues modified in the 5-, 6-positions of the address domain
BIOORGANIC & MEDICINAL CHEMISTRY
2-arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands
BIOORGANIC & MEDICINAL CHEMISTRY
Glutamate transporters combine transporter- and channel-like features
TRENDS IN BIOCHEMICAL SCIENCES
pH dependent conformational changes within the iron responsive element
BIOMETALS
Congenital insensitivity to pain with anhidrosis (CIPA): effect of TRKA (NTRK1) missense mutations on autophosphorylation of the receptor tyrosine kinase for nerve growth factor
HUMAN MOLECULAR GENETICS
Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains
CURRENT BIOLOGY
Synthesis of potent and selective dopamine D-4 antagonists as candidate radioligands
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Proteins involved in the production and perception of oligosaccharides in relation to plant and animal development
CURRENT OPINION IN STRUCTURAL BIOLOGY
Retinoid X receptor and its partners in the nuclear receptor family
CURRENT OPINION IN STRUCTURAL BIOLOGY
Piceatannol is an effective inhibitor of IgE-mediated secretion from humanbasophils but is neither selective for this receptor nor acts on syk kinase at concentrations where mediator release inhibition occurs
CLINICAL AND EXPERIMENTAL ALLERGY
Feeding suppression by fibroblast growth factor-1 is accompanied by selective induction of heat shock protein 27 in hypothalamic astrocytes
EUROPEAN JOURNAL OF NEUROSCIENCE
IgE receptors
CURRENT OPINION IN IMMUNOLOGY
Estrogen response element binding induces alterations in estrogen receptor-alpha conformation as revealed by susceptibility to partial proteolysis
JOURNAL OF MOLECULAR ENDOCRINOLOGY
Functional characterization of two anti-estradiol antibodies as deduced from modelling and site-directed mutagenesis experiments
JOURNAL OF MOLECULAR RECOGNITION
Recognition between flexible protein molecules: induced and assisted folding
JOURNAL OF MOLECULAR RECOGNITION
Glial tumor cell adhesion is mediated by binding of the FNIII domain of receptor protein tyrosine phosphatase beta (RPTP beta) to tenascin C
ONCOGENE
Overexpression of p97(Eps8) leads to cellular transformation: implication of pleckstrin homology domain in p97(Eps8)-mediated ERK activation
ONCOGENE
Dermatan sulphate is released by proteinases of common pathogenic bacteriaand inactivates antibacterial alpha-defensin
MOLECULAR MICROBIOLOGY
Experimental proof for the structure of a thrombin-inhibiting heparin molecule
CHEMISTRY-A EUROPEAN JOURNAL
Synthesis of conformationally locked L-iduronic acid derivatives: Direct evidence for a critical role of the skew-boat S-2(0) conformer in the activation of antithrombin by heparin
CHEMISTRY-A EUROPEAN JOURNAL
Serotonin receptor and transporter ligands - Current status
CURRENT MEDICINAL CHEMISTRY
Agonists at the alpha 4 beta 2 nicotinic acetylcholine receptors: Structure-activity relationships and molecular modelling
CURRENT MEDICINAL CHEMISTRY
Antagonists of the Src homology 2 (SH2) domains of Grb2, Src, Lck and ZAP-70
CURRENT MEDICINAL CHEMISTRY
The inhibitory neural circuitry as target of antiepileptic drugs
CURRENT MEDICINAL CHEMISTRY
Inhibitors of AMPA and kainate receptors
CURRENT MEDICINAL CHEMISTRY
Receptor properties of cyclic peptides composed of alternating natural amino acids and 3-aminobenzoic acid derivatives
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
Different affinity states of CCK1 receptors on pancreatic acini and gastric smooth muscle in the rat
JOURNAL OF PHYSIOLOGY-PARIS